keyword
MENU ▼
Read by QxMD icon Read
search

0303

keyword
https://www.readbyqxmd.com/read/27745718/-the-alexithymia-questionnaire-for-children-aqc-psychometric-properties-in-a-sample-of-105-adolescents-hospitalized-in-an-adolescent-psychiatric-department
#1
M Delhaye, F Orts, F Bury, G Loas
OBJECTIVE: The 20-item Toronto Alexithymia Scale (TAS-20) is the most widely used measure of alexithymia in non-clinical or clinical populations. The TAS-20 evaluates three dimensions of the alexithymia construct: the difficulty identifying feelings (DIF), the difficulty describing feelings (DDF) and externally oriented thinking (EOT). The TAS-20 is also used in adolescents or children, and the psychometric properties of the scale have not been systematically evaluated in these populations...
October 10, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27189628/distribution-of-hla-drb1-and-hla-dqb1-alleles-in-lak-population-of-iran
#2
Ali Mohammad Varzi, Farhad Shahsavar, Mohammad Javad Tarrahi
Human leukocyte antigen (HLA) genes are the most polymorphic loci in the human genome and encode the highly polymorphic molecules critically involved in immune responses. Anthropological studies based on highly polymorphic HLA genes provide useful information for bone marrow donor registry, forensic medicine, disease association studies, as well as designing peptide vaccines against tumors, and infectious or autoimmune diseases. The aim of this study was to determine the HLA-DRB1 and HLA-DQB1 allele frequencies in 100 unrelated Lak individuals from Lorestan province of Iran...
July 2016: Human Immunology
https://www.readbyqxmd.com/read/27138859/development-of-emulsifying-property-in-persian-gum-using-octenyl-succinic-anhydride-osa
#3
S Mohammadi, S Abbasi, M G Scanlon
In the present study, the influence of octenyle succinic anhydride (OSA),gum concentration, pH, temperature and reaction time on esterification of Persian gum (PG), and its soluble (SFPG) and insoluble (IFPG) fractions, were investigated by response surface methodology (RSM) in order to optimize the reaction conditions based on the degree of substitution (DS). The individual effect of all independent variables as well as the interactive effects of temperature-OSA concentration, and OSA-PG concentrations on DS was significant...
August 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27123247/association-between-the-hla-dqb1-polymorphisms-and-the-susceptibility-of-chronic-hepatitis-b-a-comprehensive-meta-analysis
#4
Jinmei Huang, Liangshi Xiong, Jin Wang, Yongfang Liu, Qirong Zhu, Jun Lei, Zhonghui Zhou
: Single-nucleotide polymorphisms in the human leukocyte antigen (HLA)-DQB1 gene are associated with chronic inflammatory and immunological diseases. Host genetic factors have a key role in the development of chronic hepatitis B (CHB). The aim of the present study was to investigate the association between the HLA-DQB1 polymorphisms and the susceptibility to CHB. PubMed, Embase, CNKI and Wanfang databases were searched for the studies that reported the association of the HLA-DQB1 polymorphisms with CHB between January 1, 1966 and July 30, 2015...
May 2016: Biomedical Reports
https://www.readbyqxmd.com/read/27008621/impaired-pancreatic-beta-cell-compensatory-function-is-the-main-cause-of-type-2-diabetes-in-individuals-with-high-genetic-risk-a-9%C3%A2-year-prospective-cohort-study-in-the-chinese-population
#5
Jing Yan, Danfeng Peng, Feng Jiang, Rong Zhang, Miao Chen, Tao Wang, Dandan Yan, Shiyun Wang, Xuhong Hou, Yuqian Bao, Cheng Hu, Weiping Jia
AIMS/HYPOTHESIS: We aimed to evaluate the combined effects of type 2 diabetes risk variants on predicting deterioration of blood glucose and progression of beta cell function and insulin sensitivity in a 9 year prospective cohort from the Chinese population. METHODS: We constructed a weighted genetic risk score (GRS) model based on 40 variants associated with type 2 diabetes validated in an established cross-sectional Chinese population (n = 6,822). The weighted scores were categorised into tertiles to assess the predictive capacity for incidence of type 2 diabetes and impaired glucose regulation (IGR), as well as for changes in Stumvoll first- and second-phase insulin secretion indices and Gutt's insulin sensitivity index (ISI) in a community-based 9 year prospective cohort (n = 2,495), including 2,192 individuals with normal glucose tolerance and 303 with IGR at baseline, through logistic, Cox and multiple linear regression tests...
July 2016: Diabetologia
https://www.readbyqxmd.com/read/26940654/systolic-diastolic-functional-coupling-in-healthy-children-and-in-those-with-dilated-cardiomyopathy
#6
Mark K Friedberg, Renee Margossian, Minmin Lu, Laura Mercer-Rosa, Heather T Henderson, Arni Nutting, Kevin Friedman, Kimberly M Molina, Karen Altmann, Charles Canter, Lynn A Sleeper, Steven D Colan
Systolic and diastolic function affect dilated cardiomyopathy (DCM) outcomes. However, systolic-diastolic coupling, as a distinct characteristic, may itself affect function but is poorly characterized. We hypothesized that echocardiographic left ventricular (LV) longitudinal systolic tissue velocities (S') correlate with diastolic longitudinal velocities (E') and that their relationship is associated with ventricular function and that this relationship is impaired in pediatric DCM. We analyzed data from the Pediatric Heart Network Ventricular Volume Variability study, using linear regression and generalized additive modeling to assess relationships between S' and E' at the lateral and septal mitral annulus...
June 1, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/26866570/hla-genetic-discrepancy-between-latent-autoimmune-diabetes-in-adults-and-type-1-diabetes-lada-china-study-no-6
#7
Shuoming Luo, Jian Lin, Zhiguo Xie, Yufei Xiang, Peilin Zheng, Gan Huang, Xia Li, Yu Liao, William A Hagopian, Cong-Yi Wang, Zhiguang Zhou
The focus of current study is to address HLA-conferred risks to T1D and LADA susceptibility, and determine their discrepancies for the HLA-conferred risks. The risks for Chinese T1D and LADA patients conferred by HLA genes significantly differ from those patients with Caucasian origin.
April 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26843554/ancient-hybrid-origin-of-the-eastern-wolf-not-yet-off-the-table-a-comment-on-rutledge-et-al-2015
#8
COMMENT
Kristina M Sefc, Stephan Koblmüller
A recent study of North American canids by Rutledge et al. (Biol. Lett. 11, 20150303 (doi:10.1098/rsbl.2015.0303)) refutes the hypothesized hybrid origin of the eastern wolf (EW) based on genomic evidence against very recent hybridization. However, the analyses do not rule out the possibility of more ancient hybridization. Claims to have resolved the evolutionary origin of the EW are therefore inappropriate. Importantly, though, we plead that uncertainty about the ancient history of the taxon should not affect current conservation policy...
February 2016: Biology Letters
https://www.readbyqxmd.com/read/26830802/-3-1-incommensurately-modulated-crystal-structure-of-cs3scsi6o15
#9
Clivia Hejny, Volker Kahlenberg, Daniela Schmidmair, Predrag Dabić
Single-crystal X-ray diffraction of Cs3ScSi6O15 shows the presence of main reflections and satellite reflections up to the fourth order along the c* direction. The (3+1)-dimensional incommensurately modulated structure was solved in superspace group X3m1(00gamma)0s0 [a = 13.861 (1), c = 6.992 (1) Å, V = 1163.4 (2) Å(3)] with a modulation wavevector q = 0.14153 (2)c*. Refinement of three modulation waves for positional and anisotropic displacement parameter values for all atoms converged to R(obs) values for all, main and satellite reflections of first, second and third order of 0...
February 2016: Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
https://www.readbyqxmd.com/read/26759224/systemic-sclerosis-and-silica-exposure-a-rare-association-in-a-large-brazilian-cohort
#10
Luiza F Rocha, Ana Paula Luppino Assad, Roberta G Marangoni, Ana Paula Toledo Del Rio, João Francisco Marques-Neto, Percival D Sampaio-Barros
The objective of this study is to describe the characteristics of patients with Erasmus syndrome (ES) in a large SSc Brazilian cohort. Nine hundred and forty-seven SSc patients attended at the Scleroderma Outpatient Clinic at two academic medical centers in Brazil and classified as SSc according to the ACR/EULAR criteria were retrospectively studied. Information on demographics, clinical, and laboratory features was obtained by chart review. ES patients had their HLA class II characterized by PCR-SSO method as available...
May 2016: Rheumatology International
https://www.readbyqxmd.com/read/26632725/tubulointerstitial-nephritis-and-uveitis-syndrome-in-an-elderly-man-case-report-and-literature-review
#11
Wen-Hui Lei, Jun Xin, Xue-Ping Yu, Jie Li, Ming-Feng Mao, Jian-Song Ji, Chui-Fen Wu, Chao-Yong Zhu, Lie Jin
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease of unknown etiology defined by the combination of tubulointerstitial nephritis, uveitis, and biochemical abnormalities. It has been reported that TINU mainly affects adolescents and young women. Here we reported a special case regarding a 60-year-old man with acute renal failure due to TINU syndrome documented by renal biopsy.We present a rare case of an elderly patient, who had been suffering from a fever for 2 weeks, characterized by sudden onset and resolving spontaneously, and accompanied by extreme fatigue, loss of appetite, and shivering...
November 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26452350/comprehensive-study-into-the-activation-of-the-plasma-enzyme-systems-during-attacks-of-hereditary-angioedema-due-to-c1-inhibitor-deficiency
#12
Dorottya Csuka, Nóra Veszeli, Éva Imreh, Zsuzsanna Zotter, Judit Skopál, Zoltán Prohászka, Lilian Varga, Henriette Farkas
BACKGROUND: The activation of plasma enzyme systems contributes to hereditary angioedema attacks. We aimed to study the activation markers of the fibrinolytic, coagulation, and contact systems in a larger number of paired samples obtained from the same C1-INH-HAE patients in symptom-free periods and during attacks. METHODS: Eleven parameters (Factors XI, XII, and C1-inhibitor activity; the concentrations of the D-dimer, prothrombin fragments 1 + 2, plasminogen, plasminogen activator inhibitor-1 [PAI-1], thrombin-anti-thrombin III [TAT] complex, fibrinogen) were measured along with prothrombin time and activated partial thromboplastin time (aPTT), using commercial kits...
2015: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/26304950/evaluating-utility-gloves-as-a-potential-reservoir-for-pathogenic-bacteria
#13
Kathy L Grant, E Donald Naber, William A Halteman
PURPOSE: This pilot study sought to determine the rate and degree to which gram-negative Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa and gram-positive Staphylococcus aureus occurred on the inside of utility gloves used at University of Maine at Augusta, Dental Health Programs' dental hygiene clinic. METHODS: Five steam autoclave utility gloves were randomly selected to serve as control and a convenience sample of 10 used utility gloves were selected from the sterilization area...
August 2015: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/26216678/reduction-of-epileptiform-activity-through-local-valproate-implants-in-a-rat-neocortical-epilepsy-model
#14
Michael P Rassner, Jonas M Hebel, Dirk-Matthias Altenmüller, Silvanie Volz, Laura S Herrmann, Thomas J Feuerstein, Thomas M Freiman
PURPOSE: Pharmacotherapy of epilepsies is limited due to low concentrations at epileptogenic foci, side effects of high systemic doses and that some potentially efficient substances do not pass the blood-brain barrier. To overcome these limitations, we tested the efficacy of local valproate (VPA)-containing polymer implants in a model of necocortical injected tetanus toxin (TeT) in the rat. METHODS: Tetanus toxin was injected intracortically and cobalt (II) chloride (CoCl2) was applied on the cortical surface...
August 2015: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/26199980/semaphorins-and-neuropilins-expression-in-salivary-gland-tumors
#15
Felipe P Fonseca, Lynne Bingle, Alan R Santos-Silva, Márcio A Lopes, Oslei P de Almeida, Bruno A B de Andrade, Fernanda V Mariano, Luiz P Kowalski, Ana L C A Rangel, Manoela D Martins, Luise Meurer, Paul M Speight, Pablo A Vargas
BACKGROUND: Salivary gland tumors (SGT) account for 3-10% of all head and neck neoplasms, and little is known about their angiogenic properties. Despite semaphorins and neuropilins have been demonstrated to be prognostic determinants in many human cancers, they remain to be investigated in SGT. Therefore, the objective of this study was to analyze the clinical significance of the expression of class 3 semaphorins A (Sema3A) and B (Sema3B) and neuropilins-1 (Np-1) and neuropilins-2 (Np-2), in SGT...
February 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/26131205/correlation-of-hla-dqb1-gene-polymorphism-of-xinjiang-uygur-with-outcome-of-hbv-infection
#16
Yongping Zhang, Fengcong Zhao, Liu Lan, Zhao Qin, Liang Jun
BACKGROUND: The aim of this study was to explore the correlation of gene polymorphisms of human leukocyte antigen-DQB1 (HLA-DQB1) with the infection outcome and replication status of hepatitis B virus (HBV) positive patients in the Xinjiang Uygur population in China. METHODS: 110 cases of chronic hepatitis B (CHB) of Xinjiang Uygur were examined clinically, which were named as the CHB group; 100 cases carrying chronic HBV (ASC) served as ASC group; 80 cases of self-limited HBV infection (RHBS) were recorded as RHBS group...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26125722/characterization-and-phylogenetic-analysis-of-the-swine-leukocyte-antigen-3-gene-from-korean-native-pigs
#17
H Y Chung, Y C Choi, H N Park
We investigated the phylogenetic relationships between pig breeds, compared the genetic similarity between humans and pigs, and provided basic genetic information on Korean native pigs (KNPs), using genetic variants of the swine leukocyte antigen 3 (SLA-3) gene. Primers were based on sequences from GenBank (accession Nos. AF464010 and AF464009). Polymerase chain reaction analysis amplified approximately 1727 bp of segments, which contained 1086 bp of coding regions and 641 bp of the 3'- and 5'-untranslated regions...
2015: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/26009879/concurrent-deletion-of-16q23-and-pten-is-an-independent-prognostic-feature-in-prostate-cancer
#18
Martina Kluth, Frederic Runte, Philipp Barow, Jazan Omari, Zaid M Abdelaziz, Lisa Paustian, Stefan Steurer, Maria Christina Tsourlakis, Margit Fisch, Markus Graefen, Pierre Tennstedt, Hartwig Huland, Uwe Michl, Sarah Minner, Guido Sauter, Ronald Simon, Meike Adam, Thorsten Schlomm
The deletion of 16q23-q24 belongs to the most frequent chromosomal changes in prostate cancer, but the clinical consequences of this alteration have not been studied in detail. We performed fluorescence in situ hybridization analysis using a 16q23 probe in more than 7,400 prostate cancers with clinical follow-up data assembled in a tissue microarray format. Chromosome 16q deletion was found in 21% of cancers, and was linked to advanced tumor stage, high Gleason grade, accelerated cell proliferation, the presence of lymph node metastases (p < 0...
November 15, 2015: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/25926118/sleep-and-glycemic-control-in-type-1-diabetes
#19
Mark Thomaz Ugliara Barone, Daniela Wey, Fabiola Schorr, Denise Reis Franco, Mario Kehdi Carra, Geraldo Lorenzi Filho, Luiz Menna-Barreto
OBJECTIVE: Our aim in the present study was to elucidate how type 1 diabetes mellitus (T1DM) and sleep parameters interact, which was rarely evaluated up to the moment. MATERIALS AND METHODS: Eighteen T1DM subjects without chronic complications, and 9 control subjects, matched for age and BMI, were studied. The following instruments used to evaluate sleep: the Epworth Sleepiness Scale, sleep diaries, actimeters, and polysomnography in a Sleep Lab. Glycemic control in T1DM individuals was evaluated through: A1C, home fingertip glucometer for 10 days (concomitant with the sleep diary and actimeter), and CGM or concomitant with continuous glucose monitoring (during the polysomnography night)...
February 2015: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/25845749/association-between-hla-drb1-0405-dqb1-0401-and-dqa1-0303-alleles-and-lamotrigine-induced-cutaneous-adverse-drug-reactions-a-pilot-case-control-study-from-japan
#20
Akiko Ito, Hiromitsu Shimada, Kazushi Ishikawa, Naoko Takeo, Yutaka Hatano, Kazumoto Katagiri, Kentaro Kohno, Yasuo Araki, Takeshi Terao, Hiroto Kojima, Chikashi Terao, Nobuoki Eshima, Sakuhei Fujiwara
BACKGROUND: Human leukocyte antigen (HLA) genotypes in lamotrigine -induced (LTG-induced) cutaneous adverse drug reactions (cADRs) have been described in several reports but controversy remains even for a given ethnic group. We attempted to clarify a possible association between LTG-induced cADRs and HLA alleles in Japanese patients. METHOD: Sixteen subjects, including eight patients with LTG-induced cADRs and eight LTG-tolerant controls were included in this study...
July 1, 2015: Journal of Affective Disorders
keyword
keyword
79852
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"