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Paracentral acute middle maculopathy

Yanyan Chen, Yuedong Hu
We report a case of idiopathic paracentral acute middle maculopathy with typical optical imaging and clinical features. A 26-year-old Chinese policeman presented with a 20-day history of paracentral scotoma in the left eye after early wake-up and long-time working in front of computer the day before. He experienced sudden-onset strong flash in his left eye. Paracentral scotoma appeared in his left eye after 6hours of rest. The general history was negative. His best corrected visual acuity was 20/20 OU. Anterior segment, dilated fundus examination, papillary evaluation and intraocular pressure were normal...
September 2017: Photodiagnosis and Photodynamic Therapy
Cheryl Haskes, Shannon Santapaola, Jordan Zinn
PURPOSE: This is a case presentation of paracentral acute middle maculopathy in a 33-year-old white man with borderline hyperlipidemia. Paracentral acute middle maculopathy was originally thought to be a variant of acute macular neuroretinopathy; however, it is now generally accepted that these two conditions are separate disease entities. The etiology, evolution, and pathophysiology of acute macular neuroretinopathy and paracentral acute middle maculopathy are discussed, as well as current diagnostic techniques...
August 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Rene Y Choi, Russell J Swan, Aimee Hersh, Albert T Vitale
PURPOSE: To review a case of bilateral diffuse chorioretinopathy as a presenting sign of juvenile dermatomyositis (JDM) and review the literature regarding retinal manifestations associated with this disease. METHODS: Review of case record and literature regarding retinal manifestations related to juvenile dermatomyositis. RESULTS: A 13-year-old girl presented with bilateral diffuse chorioretinopathy as the presenting sign of juvenile dermatomyositis...
April 27, 2017: Ocular Immunology and Inflammation
Syed Amal Hussnain, Patrick A Coady, Kathleen M Stoessel
We present a case of paracentral acute middle maculopathy (PAMM) in a patient with sickle cell disease (SCD). Though gradual capillary loss may contribute to pathophysiology of sickle cell retinopathy as well, our case suggests that PAMM may be the precursor lesion to macular thinning commonly observed in patients with SCD. In addition, fluorescein angiography may be unable to detect these acute vascular events occurring at the deep capillary plexus.
April 26, 2017: BMJ Case Reports
Michael N Cohen, Sabin Dang, Michelle C Liang
No abstract text is available yet for this article.
April 2017: Ophthalmology
Katarina Creese, Daini Ong, Sukhpal S Sandhu, David Ware, C Alex Harper, Salmaan H Al-Qureshi, Sanjeewa S Wickremasinghe
IMPORTANCE: Paracentral acute middle maculopathy (PAMM) diagnosed by spectral domain optical coherence tomography (SD-OCT) in patients with poor visual outcome post cataract surgery. BACKGROUND: Case series of severe vision loss due to PAMM after cataract surgery. DESIGN: Retrospective case series. PARTICIPANTS: Cases from five surgical centres in Victoria, Australia. METHODS: Retrospective analysis of cases with unexplained 'patch-off' vision loss post cataract surgery...
March 13, 2017: Clinical & Experimental Ophthalmology
Khalil Ghasemi Falavarjani, Nopasak Phasukkijwatana, K Bailey Freund, Emmett T Cunningham, Ananda Kalevar, H Richard McDonald, Rosa Dolz-Marco, Philipp K Roberts, Irena Tsui, Richard Rosen, Lee M Jampol, Srinivas R Sadda, David Sarraf
PURPOSE: To assess the spectrum of perivenular ischemia in eyes with retinal vascular obstruction (typically central or hemicentral retinal vein obstruction) using en face optical coherence tomography (OCT). DESIGN: Retrospective observational case series. METHODS: Eyes with recent retinal vascular occlusion illustrating paracentral acute middle maculopathy (PAMM) in a perivenular fern-like pattern with en face OCT were evaluated in this study...
May 2017: American Journal of Ophthalmology
Matthew G J Trese, Aristomenis Thanos, Yoshihiro Yonekawa, Sandeep Randhawa
The authors present the first case of paracentral acute middle maculopathy as a manifestation of primary antiphospholipid syndrome (APS) with multimodal imaging, including optical coherence tomography angiography (OCTA). The association between APS and ophthalmic sequela is well-known. Recent advances in multimodal imaging, specifically OCTA, allow for better characterization of the mechanism and extent by which retinal arterial thrombosis can cause vision loss. Using advanced imaging modalities, the authors provide a comprehensive assessment of retinal ischemia, which showed not only localized capillary occlusion, but also ischemia of the deep retinal capillary plexus...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
David J Browning, Omar S Punjabi, Chong Lee
PURPOSE: To determine the relationship between different spectral domain optical coherence tomography (SD-OCT) signs of retinal ischemia in acute central retinal vein occlusion (CRVO) and whether they predict anterior segment neovascularization (ASNV). DESIGN: Retrospective, observational study. SUBJECTS: Thirty-nine consecutive patients with acute CRVO and 12 months of follow-up. METHODS: We graded baseline SD-OCTs for increased reflectivity of the inner retina, loss of definition of inner retinal layers, presence of a prominent middle-limiting membrane (p-MLM) sign, and presence of paracentral acute middle maculopathy (PAMM)...
2017: Clinical Ophthalmology
Jayanth Sridhar, Abtin Shahlaee, Wen-Shi Shieh, Ehsan Rahimy
PURPOSE: To report a single case of paracentral acute middle maculopathy in association with retinal artery occlusion in the setting of ipsilateral facial cosmetic filler injection. METHODS: Case report. PATIENT: A 35-year-old woman presenting with sudden vision loss to finger count vision immediately after left nasal fat pad cosmetic filler injection. RESULTS: Dilated funduscopic examination revealed a swollen optic disc with multiple branch arterial occlusions with visible embolic material...
January 2017: Retinal Cases & Brief Reports
Nicholas A Iafe, Tania Onclinx, Irena Tsui, David Sarraf
PURPOSE: To report a case of reperfused central retinal artery occlusion causing a globular pattern of paracentral acute middle maculopathy with en face optical coherence tomography (OCT). METHODS: Retrospective case report. Widefield fluorescein angiography, en face OCT, and OCT-angiography were performed. Retinal capillary plexus vessel density (mm) was measured using OCT-angiography analysis and was defined as total vessel length (mm) per area (mm). RESULTS: A 76-year-old female presented with decreased vision in the left eye for 1 day...
January 2017: Retinal Cases & Brief Reports
Nopasak Phasukkijwatana, Mansour Rahimi, Nicholas Iafe, David Sarraf
A 21-year-old healthy female presented with acute-onset vision loss in the left eye. Multimodal imaging, including fundus photography and fluorescein angiography, was unremarkable. En face optical coherence tomography (OCT) demonstrated paracentral acute middle maculopathy (PAMM) lesions in a perivenular fern-like pattern leading to the diagnosis of central retinal vein occlusion (CRVO). En face OCT can be an important modality to identify the distribution of abnormalities of the middle retina such as PAMM...
September 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Azadeh Khatibi
PURPOSE: To report a case of Purtscher-like retinopathy with paracentral acute middle maculopathy preceded by febrile illness after filler injection into the buttock muscles bilaterally for cosmesis to achieve a "Brazilian booty." METHODS: Retrospective case report. RESULTS: A 35-year-old female presented with febrile illness and then decreased vision after repeat polymethyl methacrylate injections into her buttock muscles in Mexico. Examination was significant for retinal whitening, especially in the perifoveal areas, and intraretinal hemorrhages...
August 22, 2016: Retinal Cases & Brief Reports
Paul Baciu, Candice M Nofar, Justin Spaulding, Hua Gao
PURPOSE: To report the occurrence of a branch retinal artery occlusion with paracentral acute middle maculopathy in an otherwise healthy young man with a history of livedo reticularis (LR). METHODS: Retrospective case report. PATIENTS: A 21-year-old man with a history of LR being treated with pentoxifylline developed an acute branch retinal artery occlusion with initial best-corrected visual acuity at presentation of 20/80. RESULTS: A thorough diagnostic work up was negative for potential causes of branch retinal artery occlusion or LR...
October 2017: Retinal Cases & Brief Reports
Motoharu Tokimitsu, Masako Murata, Yuichi Toriyama, Takao Hirano, Yasuhiro Iesato, Toshinori Murata
BACKGROUND: Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in a chronic case of unexplained scotoma that developed after femoral fracture. The patient exhibited normal fluorescein angiography (FA) findings and a normal retinal appearance...
July 19, 2016: BMC Ophthalmology
G Casalino, M Williams, C McAvoy, F Bandello, U Chakravarthy
PurposeTo report the clinical course and the optical coherence tomography angiography (OCTA) findings of patients presenting with paracentral acute middle maculopathy (PAMM) and central retinal vein occlusion (CRVO).MethodsRetrospective case series. Clincal records and multimodal imaging findings of patients presenting with PAMM and CRVO were reviewed.ResultsThree eyes of three patients (2 males; mean age: 66 years) were included in the study. Mean follow-up was 9 months and images using OCTA (AngioVue OCT angiography system, Optovue, Inc...
June 2016: Eye
Julia Nemiroff, Nopasak Phasukkijwatana, David Sarraf
Paracentral acute middle maculopathy (PAMM) is defined by the spectral-domain optical coherence tomography (OCT) finding of paracentral hyper-reflective band-like lesions of the inner nuclear layer (INL) of the macula that progress to corresponding areas of severe INL thinning. En face analysis has enabled more detailed analyses and quantifications of these lesions and has provided insights into the pathogenesis of this abnormality. While there is a wealth of demographic and anatomical data indicating that these PAMM lesions are the result of an INL infarct, OCT angiography is the first modality to provide direct evidence...
2016: Developments in Ophthalmology
Julia Nemiroff, Laura Kuehlewein, Ehsan Rahimy, Irena Tsui, Rishi Doshi, Alain Gaudric, Michael B Gorin, SriniVas Sadda, David Sarraf
PURPOSE: To assess microvascular blood flow of the deep retinal capillary plexus in eyes with paracentral acute middle maculopathy using optical coherence tomography (OCT) angiography. DESIGN: Retrospective, multicenter observational case series. METHODS: Clinical and multimodal imaging findings from 8 patients with paracentral acute middle maculopathy were reviewed and analyzed. OCT angiography scans were analyzed and processed, and vessel density was calculated...
February 2016: American Journal of Ophthalmology
Paula E Pecen, Adiel G Smith, Justis P Ehlers
No abstract text is available yet for this article.
December 2015: JAMA Ophthalmology
M Ali Khan, Ehsan Rahimy, Abtin Shahlaee, Jason Hsu, Allen C Ho
The authors describe a case of para-central acute middle maculopathy (PAMM) in a 75-year-old man who had recently undergone cardiac catheterization. Imaging with simultaneous en face optical coherence tomography (OCT) and OCT angiography (OCTA) revealed signal abnormalities localized to the deep capillary plexus. This case highlights the ability of OCTA to image and localize retinal disease by vascular distribution, previously difficult with conventional fluorescein angiography, and lends evidence to the belief that PAMM is caused by vascular injury to the intermediate and deep capillary plexus...
October 2015: Ophthalmic Surgery, Lasers & Imaging Retina
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