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Posterior uveitis

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https://www.readbyqxmd.com/read/28630786/ophthoselfie-detailed-self-imaging-of-cornea-and-anterior-segment-by-smartphone
#1
Abdullah Kaya
OBJECTIVES: To describe the ophthoselfie, a method by which everyone can take detailed self-images of the cornea and anterior segment with a smartphone. MATERIALS AND METHODS: A 90-diopter non-contact double aspheric lens was attached to posterior camera of the smartphone by clear tape. Images of one eye on the screen of the smartphone could be seen with the other eye in the mirror and images were taken. RESULTS: Accurate and detailed images of the cornea and anterior segment of the eye could be taken...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28629400/characteristics-of-syphilitic-uveitis-in-northern-china
#2
Xiaomin Zhang, Qian Du, Feifei Ma, Yinglong Lu, Meiyan Wang, Xiaorong Li
BACKGROUND: To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS: A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS: Twenty-one patients (33 eyes) were diagnosed as syphilitic uveitis. Posterior segment involvement was found in 32 eyes (97.0%). Vitreous haze, neuroretinitis, and posterior placoid chorioretinitis were mainly found in patients with a relatively short duration of the disease, while diffuse chorioretinitis, pseudoretinitis pigmentosa, cystoid macular edema, and epiretinal membrane were found in patients with relatively long duration of ocular involvement...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28624167/longitudinal-vision-related-quality-of-life-for-patients-with-noninfectious-uveitis-treated-with-fluocinolone-acetonide-implant-or-systemic-corticosteroid-therapy
#3
Elizabeth A Sugar, Vidya Venugopal, Jennifer E Thorne, Kevin D Frick, Gary N Holland, Robert C Wang, Robert Almanzor, Douglas A Jabs, Janet T Holbrook
PURPOSE: To evaluate longitudinal vision-related quality of life (VRQoL) in patients with noninfectious uveitis. DESIGN: Cohort study using randomized controlled trial data. PARTICIPANTS: Patients with active or recently active intermediate uveitis, posterior uveitis, or panuveitis enrolled in the Multicenter Steroid Treatment Trial and Follow-up Study. METHODS: Data from the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) for the first 3 years after randomization were evaluated semiannually...
June 14, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28602016/long-term-results-of-cataract-surgery-in-patients-with-anterior-uveitis
#4
Ozgur Balta, Gulten Sungur, Mehmet Akif Acar, Mustafa Kosker, Mehmet Yakin, Firdevs Ornek
PURPOSE: This study was aimed to assess the long-term results of phacoemulsification and posterior chamber intraocular lens implantation in patients with anterior uveitis. METHODS: Patients with complicated cataract secondary to anterior uveitis who underwent phacoemulsification and posterior chamber intraocular lens implantation were included in this study. Long-term results and all complications were evaluated throughout the postoperative 4 years. RESULTS: A total of 55 eyes of 48 patients were identified in this study...
June 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28601910/the-clinical-outcomes-of-surgical-management-of-anterior-chamber-migration-of-a-dexamethasone-implant-ozurdex%C3%A2
#5
Hyunseung Kang, Min Woo Lee, Suk Ho Byeon, Hyoung Jun Koh, Sung Chul Lee, Min Kim
PURPOSE: Our purpose was to describe the clinical course, and individualized management approaches, of patients with migration of a dexamethasone implant into the anterior chamber. METHODS: This was a retrospective review of four patients with seven episodes of anterior chamber migration of a dexamethasone implant. RESULTS: After 924 intravitreal dexamethasone injections, anterior migration of the implant occurred in four eyes of four patients (0...
June 10, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28591283/outcomes-of-phacoemulsification-in-patients-with-uveitis-at-a-tertiary-center-in-s%C3%A3-o-paulo-brazil-a-review-of-cases-from-2007-to-2012
#6
Patrícia M G Cerqueira, Felipe T B Gaspar C da Silva, Pedro Carlos Carricondo, Edilberto Olivalves, Carlos Eduardo Hirata, Joyce Hisae Yamamoto
Purpose: To evaluate the outcomes of phacoemulsification with intraocular lens (IOL) implantation in eyes with uveitis. Methods: Consecutive patients with uveitis and cataracts who had phacoemulsification and acrylic IOL implantation during 2007-2012 were evaluated for visual outcomes, etiology, and complications. Inflammation was controlled for at least 3 months before surgery, and oral prednisone (0.5 mg/kg/day) was administered to patients with non-infectious uveitis...
March 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28585111/morphometric-features-on-enhanced-depth-imaging-optical-coherence-tomography-scans-in-idiopathic-posterior-uveitis-or-panuveitis
#7
Rupesh Agrawal, Rashi Arora, Pearse A Keane, Aniruddha Agarwal, Carlos Pavesio
PURPOSE: Enhanced depth imaging (EDI) optical coherence tomography (OCT) has emerged as a novel tool for qualitative and quantitative choroidal assessment in posterior uveitis. The objective of this study was to investigate the role of EDI-OCT to assess the choroidal and retinal changes in posterior uveitis. METHODS: In this retrospective study, EDI-OCT scans of patients with idiopathic posterior uveitis or panuveitis were reviewed. Morphological features from retina and choroid from the OCT scans were assessed and compared to the fellow normal eyes...
June 5, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28540008/predictors-of-successful-laser-capsulotomy-for-significant-posterior-capsule-opacification-after-phacoemulsification
#8
Brijesh Takkar, Parijat Chandra, Shreyas Temkar, Ashutosh Kumar Singh, Indrish Bhatia
PURPOSE: This study aimed to determine the reasons behind the failure of laser capsulotomy (LC) performed for significant posterior capsular opacification (PCO). METHODS: Eighty-eight eyes of 88 patients referred for LC at a tertiary care center were retrospectively analyzed. The data recorded included the cause of cataract, visual acuity, duration of PCO, location of PCO, intraocular lens (IOL) position, IOL type, and lens capsule status. These data were later analyzed for determining the requirement of high pulse energy during LC and the success rate of primary LC...
April 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28539679/the-association-of-pathergy-reaction-and-active-clinical-presentations-of-beh%C3%A3-et-s-disease
#9
Shirin Assar, Bahar Sadeghi, Fereydoun Davatchi, Seyyedeh Zahra Ghodsi, Abdolhadi Nadji, Farhad Shahram, Farimah Ashofte, Seyyedeh Roghieh Larimi, Masoud Sadeghi
OBJECTIVES: The pathergy skin test is a hypersensitivity reaction to a prick skin trauma caused by a pin or a needle, which is considered as a specific presentation in Behçet's disease (BD) and the precise mechanism of this test is not well elucidated. This study was designed to evaluate the association of pathergy reaction (PR) with the active clinical manifestations of BD patients, to assess the clinical importance of PR. MATERIALS AND METHODS: This was a cohort study on 1675 BD patients who fulfilled the entry criteria based on the International Criteria for Behçet's Disease (ICBD) from 1975 to 2011...
2017: Reumatologia
https://www.readbyqxmd.com/read/28537523/the-pattern-of-uveitis-in-sri-lanka
#10
Jay Siak, Mirna Kumaradas, Soon-Phaik Chee
PURPOSE: To describe the pattern of uveitis at a tertiary uveitis referral clinic in Sri Lanka. METHODS: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed. RESULTS: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). 485 (65%) were idiopathic...
May 24, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28524639/high-dose-intravenous-steroid-pulse-therapy-in-ocular-involvement-of-behcet-s-disease-a-pilot-double-blind-control-study
#11
Mastaneh Mohammadi, Farhad Shahram, Hormoz Shams, Massoomeh Akhlaghi, Farimah Ashofteh, Fereydoun Davatchi
AIM: To evaluate the efficacy of intravenous high-dose pulses of methylprednisolone (IVPM) for treatment of ocular involvement in Behcet's disease (BD). METHOD: In a double-blind control study, we randomized BD patients with posterior uveitis (PU) and/or retinal vasculitis (RV) into two groups. They received either IVPM (1000 mg methylprednisolone) or placebo for 3 consecutive days. Both groups received combination therapy with IV cyclophosphamide, azathioprine and prednisolone for 6 months...
May 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28520640/twenty-four-month-follow-up-of-tocilizumab-therapy-for-refractory-uveitis-related-macular-edema
#12
Marina Mesquida, Blanca Molins, Victor Llorenç, María V Hernández, Gerard Espinosa, Maite Sainz de la Maza, Alfredo Adán
BACKGROUND: To report the 24-month efficacy and safety of the interleukin-6 receptor antagonist tocilizumab (TCZ) for refractory uveitis-related macular edema (ME). METHODS: Data were obtained by standardized chart review. Patients with quiescent uveitis seen at a single tertiary referral center, for whom ME was the principal cause of reduced visual acuity. OUTCOME MEASURES: Central foveal thickness measured by optical coherence tomography; degree of anterior and posterior chamber; inflammation (Standardization of Uveitis Nomenclature Working Group criteria); and visual acuity (Snellen and logarithm of the minimum angle of resolution) were recorded in all patients during TCZ therapy at months 1, 3, 6, 12, 18, and 24...
May 16, 2017: Retina
https://www.readbyqxmd.com/read/28516270/-ocular-sarcoidosis
#13
REVIEW
C Springer-Wanner, T Brauns
Ocular manifestation of sarcoidosis occurs in up to 60% of patients with confirmed systemic sarcoidosis and represents one of the most common forms of noninfectious uveitis. In known pulmonary sarcoidosis, ocular involvement can occur in up to 80% of cases. Sarcoidosis can also present only in the eye, without a systemic manifestation (ocular sarcoidosis). Typically, ocular sarcoidosis shows bilateral granulomatous uveitis and can involve all parts of the eye. Apart from an acute anterior uveitis, chronic intermediate or posterior uveitis can be found...
June 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28508165/frequency-of-toxoplasma-gondii-in-the-retina-in-eye-banks-in-brazil
#14
Deise F Costa, Heloisa Nascimento, Aline Sutili, Fernando A J Nobrega, Flavio Fowler, Mario Junqueira Nobrega, Cristina Garrido, Janaina de Oliveira Dias, Consuelo B D Adán, Luiz Vicente Rizzo, Claudio Silveira, Rubens Belfort, Alessandra G Commodaro
Ocular toxoplasmosis is the main cause of posterior uveitis worldwide frequently leading to vision loss. In Brazil, the seroprevalence of Toxoplasma gondii infection ranges from 50 to 80% depending of the region studied. The frequency of toxoplasmic retinal scar may reach 18% of the adults in the South of Brazil. Our goal was to determine the frequency of T. gondii DNA in retinas from eye banks from different regions in Brazil. A total of 162 eyes were obtained from eye banks in Manaus (n = 60), Sao Paulo (n = 60), Chapeco (n = 26), and Joinville (n = 16)...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28503960/management-of-severe-complications-in-beh%C3%A3-et-s-disease-with-tnf-inhibitors
#15
A C Desbois, H Vallet, F Domont, C Comarmond, P Cacoub, D Saadoun
The efficacy of anti-TNFα agents has been recently evaluated in many studies in Behçet's disease (BD), particularly in ocular and life-threatening manifestations such as neurological and vascular disease. Areas covered: The following article aims to summarize the currently available efficacy and safety data of anti-TNFα agents in BD. Expert opinion: Most studies have shown dramatic and rapid efficacy with anti-TNFα agents on the main BD-associated issues including posterior uveitis, gastro-intestinal and neurological complications as well as major vessel disease...
July 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28503298/patterns-of-ocular-inflammation-in-patients-with-miliary-tuberculosis
#16
Salil Mehta
BACKGROUND: Ocular morbidity associated with systemic tuberculosis is common. The clinical picture varies from anterior uveitis, intermediate uveitis and posterior uveitis to even panuveitis. There is little data on the correlation between specific systemic presentations and the ocular inflammation. We conducted a retrospective review of the ocular findings in the case records of patients admitted with a diagnosis of miliary tuberculosis. These patients were then referred for a more detailed ophthalmic evaluation...
2017: F1000Research
https://www.readbyqxmd.com/read/28501709/calcium-ion-coordinated-dexamethasone-supramolecular-hydrogel-as-therapeutic-alternative-for-control-of-non-infectious-uveitis
#17
Wei Wu, Zhaoliang Zhang, Taotao Xiong, Wenguang Zhao, Rou Jiang, Hao Chen, Xingyi Li
Supramolecular hydrogel formed by the self-assembly of therapeutic agents have received considerable attention due to its high drug payload and carrier-free features. Herein, we constructed a dexamethasone sodium phosphate (Dex) supramolecular hydrogel in combination of Dex and calcium ion (Ca(2+)) and further demonstrated its therapeutic efficacy in the control of ocular inflammation. The developed supramolecular hydrogel was thoroughly characterized by rheology, TEM, FTIR and XRD. Calcium ions and Dex concentration had markedly influence on the sol-gel transition behaviour of hydrogel and the proposed Dex supramolecular hydrogel displayed thixotropic property...
May 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28496372/choroidal-extranodal-marginal-zone-lymphoma-diagnosed-by-full-thickness-retinochoroidal-biopsy-case-report-and-review-of-the-literature
#18
Ali Dirani, Guy Allaire, Sonia Callejo, Marie Lyne Belair, Katarzyna Biernacki, Christine Corriveau, Karim Hammamji
The case of an 89-year-old man who was referred for a painless decrease of vision in his right eye (RE) is reported. Fundus examination of the RE showed an elevated amelanotic lesion located in the posterior pole with an adjacent focal round pigmented lesion. There was also a more peripheral amelanotic lesion extending from 6 to 9 o'clock clockwise inferotemporally. Uveitis workup and imaging studies of brain and orbits were normal. A retinochoroidal biopsy was done and showed the presence of choroidal extranodal marginal zone lymphoma...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28492430/spectral-domain-optical-coherence-tomography-findings-in-endogenous-candida-endophthalmitis-and-their-clinical-relevance
#19
Alessandro Invernizzi, Richard Symes, Elisabetta Miserocchi, Mariano Cozzi, Matteo Cereda, Giovanni Fogliato, Giovanni Staurenghi, Luca Cimino, Peter McCluskey
PURPOSE: To describe vitreal, retinal, and choroidal features of eyes affected by Endogenous candida endophthalmitis (ECE) analyzed by spectral domain optical coherence tomography (SD-OCT) and to evaluate their clinical impact. METHODS: Medical records and SD-OCT images from eyes diagnosed with ECE at four retina and uveitis tertiary referral centers were retrospectively evaluated. Spectral domain optical coherence tomography images were analyzed to evaluate the structural changes occurring in the vitreous, the retina, and the choroid in areas involved by ECE...
May 10, 2017: Retina
https://www.readbyqxmd.com/read/28484648/the-effectiveness-of-pre-and-postoperative-infliximab-in-controlling-beh%C3%A3-et-s-disease-posterior-uveitis-in-patients-undergoing-vitrectomy-a-preliminary-study
#20
Hossam El Din Mohamed Khalil, Heba A El Gendy, Hala Ahmed Raafat, Hazem Effat Haroun, Tamer Atef Gheita, Hossam Mahmoud Bakir
Purpose. To evaluate the short-term effectiveness of infliximab in controlling ocular manifestations in Behçet's Disease (BD) patients candidate for pars plana vitrectomy, if given in a regimen before and after the planned procedure. Patients and Methods. 30 eyes of 27 adult male BD patients with a mean age of 35.56 yrs presented with refractory posterior uveitis not responding to immunosuppressive drugs and candidate for vitrectomy were included. Infliximab was given in a dose of 5 mg/kg intravenous infusion once every two weeks for 3 treatment sessions before the intended vitrectomy followed by 3 treatment sessions at two-week intervals, after vitrectomy...
2017: Journal of Ophthalmology
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