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https://www.readbyqxmd.com/read/28684101/acquired-unilateral-scotoma
#1
Amir H Marvasti, Kevin C Chen, Henry A Ferreyra, Julie Falardeau
A 54-year-old white man presented with a "blind spot" temporally in his left eye. Best-corrected visual acuity in the affected eye was 20/20 and Humphrey visual field revealed an enlarged blind spot. Funduscopic examination revealed subtle peripapillary pigmentary changes corresponding to a well-demarcated peripapillary region of hyper- and hypoautofluorescence on fundus autofluorescence (FAF). Outer retinal degenerative changes were detected on spectral domain optical coherence tomography (SD-OCT). A diagnosis of Acute zonal occult outer retinopathy (AZOOR) was made based on clinical history and imaging studies...
July 3, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28573534/the-clinical-characteristics-and-prognosis-of-acute-zonal-occult-outer-retinopathy
#2
Shancheng Si, Wei Song, Yifan Song, Yuntao Hu
PURPOSE: This prospective observational case series study aimed to observe the clinical characteristics of acute zonal occult outer retinopathy (AZOOR) and its prognosis in Chinese Han patients. METHODS: Six eyes of 5 female patients diagnosed with AZOOR were followed up for 4 months to observe the natural disease course. All enrolled subjects underwent a series of ocular examinations at the onset and each return visit, including best corrected visual acuity (BCVA), split lamp microscopy, fundus photography, optical coherence tomography (OCT), perimetry, multifocal electroretinogram and fundus fluorescein angiography...
June 1, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28297032/ultra-wide-field-fundus-autofluorescence-and-spectral-domain-optical-coherence-tomography-findings-in-syphilitic-outer-retinitis
#3
Mohamed G A Saleh, John Peter Campbell, Paul Yang, Phoebe Lin
BACKGROUND AND OBJECTIVE: To determine the ultra-wide-field fundus autofluorescence (UWFFAF) and optical coherence tomography (OCT) features of syphilitic outer retinopathy (SOR). PATIENTS AND METHODS: Retrospective chart review. RESULTS: Three patients with SOR were investigated. Treatment with parenteral penicillin led to improvement of outer retinopathy, visual acuity, and symptoms. UWFFAF showed speckled hyperautofluorescence, hypoautofluorescence, and normal autofluorescence, similar to what has been described as a trizonal pattern in acute zonal occult outer retinopathy (AZOOR) in the chronic case of SOR, but with hyperautofluorescent areas in the two acute cases...
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28253223/observation-and-clinical-pattern-in-patients-with-white-dot-syndromes-the-role-of-color-photography-in-monitoring-ocular-changes-in-long-term-observation
#4
Joanna Brydak-Godowska, Joanna Gołębiewska, Monika Turczyńska, Joanna Moneta-Wielgoś, Agnieszka Samsel, Piotr K Borkowski, Michał Ciszek, Agnieszka Płonecka-Rodzoch, Aleksandra Kużnik-Borkowska, Joanna Ciszewska, Elżbieta Makomaska-Szaroszyk, Lidia B Brydak, Dariusz Kęcik
BACKGROUND The aim of this study was to assess the clinical course and distinctive features of different white dot syndromes (WDS) in patients attending the Ophthalmology Department, Medical University of Warsaw in the years 1995-2015. MATERIAL AND METHODS Sixty-two (62) patients (43 females and 19 males), aged 18 to 77 years, referred with a WDS were included in this prospective study, with observation period ranging from 5 months to 16 years. All patients underwent a complete ophthalmological examination and multimodal imaging studies...
March 2, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28252457/acute-zonal-occult-outer-retinopathy-associated-with-retrobulbar-optic-neuritis
#5
Jay C Wang, Avni P Finn, Lindsay A Grotting, Lucia Sobrin
A 17-year-old girl presented with unilateral retrobulbar optic neuritis as well as bilateral funduscopic findings and outer retinal dysfunction suggestive of acute zonal occult outer retinopathy (AZOOR). Fundus autofluorescence abnormalities, visual field loss, and electroretinographic changes were supportive of bilateral AZOOR. MRI was consistent with the diagnosis of clinically isolated syndrome (CIS), which is defined as a central nervous system demyelinating event that may herald the onset of multiple sclerosis (MS)...
February 28, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28245443/fundus-autofluorescence-imaging-in-the-assessment-of-acute-zonal-occult-outer-retinopathy
#6
Qian Wang, Libin Jiang, Weiyu Yan, Wenbin Wei, Timothy Y Y Lai
PURPOSE: To evaluate the fundus autofluorescence (FAF) findings in eyes with acute zonal occult outer retinopathy (AZOOR) and the relationships between the FAF, spectral-domain optical coherence tomography (SD-OCT), and Humphrey visual field (HVF) findings. METHODS: We performed a retrospective review of the clinical features and FAF, SD-OCT, and HVF findings of 23 eyes of 22 consecutive patients with AZOOR. The mean deviation (MD) values of HVF were compared between areas of normal and abnormal FAF...
2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27993590/prevalence-of-antiretinal-antibodies-in-acute-zonal-occult-outer-retinopathy-a%C3%A2-comprehensive-review-of-25-cases
#7
Cynthia X Qian, Angeline Wang, David L DeMill, Thiran Jayasundera, Kari Branham, Maria Fernanda Abalem, Naheed Khan, John R Heckenlively
PURPOSE: To perform a comprehensive review and to investigate the presence and role of autoimmune antibodies in 25 cases of acute zonal occult outer retinopathy (AZOOR) identified using the classification originally proposed by J. Donald Gass. DESIGN: Observational case series. METHODS: Setting: Institutional. STUDY POPULATION: Twenty-five patients were identified by characteristic symptoms (abrupt onset of photopsias, followed by large scotomata at or connected to the blind spot), ocular findings (paucity of pigmentary changes with no sign of vitreous inflammation and abnormal electroretinogram in at least 1 eye), and a negative family history for retinitis pigmentosa...
April 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27824724/multiple-evanescent-white-dot-syndrome-with-central-visual-loss
#8
REVIEW
Gaetano R Barile, Sarah A Harmon
PURPOSE: To report the clinical case of a 64-year-old man who developed several features of multiple evanescent white dot syndrome (MEWDS) but with central visual loss that persisted because of significant structural macular disease. METHODS: A case report was generated by a review of the clinical course and imaging investigations of one patient, along with review of the literature. RESULTS: A 64-year-old man noted decreased vision in the right eye for 2 weeks, associated with a central scotoma with shimmering, gauze effect of the vision...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27755372/ultra-wide-field-fundus-autofluorescence-findings-in-patients-with-acute-zonal-occult-outer-retinopathy
#9
Amde Selassie Shifera, Mark E Pennesi, Paul Yang, Phoebe Lin
PURPOSE: To determine whether ultra-wide-field fundus autofluorescence (UWFFAF) findings in acute zonal occult outer retinopathy correlated well with perimetry, optical coherence tomography, and electroretinography findings. METHODS: Retrospective observational study on 16 eyes of 10 subjects with AZOOR seen at a single referral center from October 2012 to March 2015 who had UWFFAF performed. Chi-square analysis was performed to compare categorical variables, and Mann-Whitney U test used for comparisons of nonparametric continuous variables...
June 2017: Retina
https://www.readbyqxmd.com/read/27693838/pure-small-cell-carcinoma-of-the-prostate-preceded-by-acute-zonal-occult-outer-retinopathy-a-case-report
#10
Daniel Ching, Matthew Brown, Cindy Forrest, Dickon Hayne
INTRODUCTION: Pure small cell prostate cancer (SCPC) cases are very rare. Acute zonal occult outer retinopathy (AZOOR) has been described as a non-neoplastic retinopathy. We report the first case of pure SCPC preceded by AZOOR in the literature. CASE REPORT: A 59year old gentleman presented with an obstructed infected urinary system. He had a diagnosis of AZOOR 6 months ago that was investigated with full body imaging without any suspicious findings. However, the most recent CT findings demonstrated extensive disease dissemination...
September 22, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27243784/acute-zonal-occult-outer-retinopathy-affecting-the-peripheral-retina-with-centripetal-progression
#11
Anna C S Tan, Jerome Sherman, Lawrence A Yannuzzi
PURPOSE: To describe a variant of acute zonal occult outer retinopathy (AZOOR) that has concentric involvement of the peripheral retina with centripetal progression toward the posterior pole. METHODS: Three patients with AZOOR were reported to show peripheral concentric zonal involvement with centripetal progression of their disease from the periphery to the posterior fundus. RESULTS: All three cases involved elderly hyperopic women with a history of autoimmune disease...
April 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/26266044/the-fundus-autofluorescence-spectrum-of-punctate-inner-choroidopathy
#12
Miaoling Li, Xiongze Zhang, Feng Wen
Purpose. To investigate the fundus autofluorescence (FAF) spectrum of punctate inner choroidopathy (PIC). Methods. This is a retrospective observational case series of 27 consecutive patients with PIC admitted from October 2013 to March 2015, who underwent short-wavelength- (SW-) and near-infrared- (NIR-) FAF imaging, spectral domain optical coherence tomography (SD-OCT), fluorescein angiography (FA), and indocyanine green angiography (ICGA). Results. There were three primary findings on the FAF imaging of patients with PIC...
2015: Journal of Ophthalmology
https://www.readbyqxmd.com/read/26258275/improved-photoreceptor-function-in-male-acute-zonal-occult-outer-retinopathy
#13
Tsutomu Sakai, Tamaki Gekka, Kenichi Kohzaki, Hiroshi Horiguchi, Keigo Shikishima, Hiroshi Tsuneoka
PURPOSE: To describe male acute zonal occult outer retinopathy (AZOOR) patients with improvement of photoreceptor structure and visual function. CASE SERIES: Medical records for eight eyes in seven patients (mean age, 36.9 years; range, 22 to 57 years) with AZOOR were reviewed retrospectively. Of the seven patients, four were treated with high-dose methylprednisolone therapy and three were not treated. All patients presented with photopsias and severe vision loss in the affected eyes...
October 2015: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/25930180/-progressive-scotoma-with-perception-of-photopsia
#14
S Bemme, U Pleyer, N Salehi, S Naxer, J Callizo, H Hoerauf, N Feltgen
Acute annular outer retinopathy (AAOR) is a very rare variant of acute zonal occult outer retinopathy (AZOOR). Both variants are characterized by the perception of a progressive visual field defect and can be accompanied by photopsia. In contrast to AZOOR, a progressive whitish and annular demarcation of the involved retina is observed in AAOR using ophthalmoscopy. Optical coherence tomography (OCT) reveals morphological changes predominantly in the outer retinal layers. Although there is no proof of an effective therapy, in the case presented here further progression could be stopped by a combination of antiviral and immunosuppressive therapy...
January 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/25923954/near-infrared-reflectance-imaging-in-eyes-with-acute-zonal-occult-outer-retinopathy
#15
Shinji Ueno, Kenichi Kawano, Yasuki Ito, Eimei Ra, Ayami Nakanishi, Masatoshi Nagaya, Hiroko Terasaki
PURPOSE: To investigate the confocal scanning laser ophthalmoscopic images obtained with near-infrared (IR) light in eyes with acute zonal occult outer retinopathy (AZOOR). METHODS: Observational case series. The medical records of 12 eyes of 10 patients with AZOOR were reviewed. Scanning laser ophthalmoscopic images obtained from the AZOOR eyes were compared with images obtained by spectral-domain optical coherence tomography, by fundus autofluorescence, and by an adaptive optics fundus camera...
August 2015: Retina
https://www.readbyqxmd.com/read/25919689/acute-zonal-occult-outer-retinopathy-in-japanese-patients-clinical-features-visual-function-and-factors-affecting-visual-function
#16
Saho Saito, Wataru Saito, Michiyuki Saito, Yuki Hashimoto, Shohei Mori, Kousuke Noda, Kenichi Namba, Susumu Ishida
PURPOSE: To evaluate the clinical features and investigate their relationship with visual function in Japanese patients with acute zonal occult outer retinopathy (AZOOR). METHODS: Fifty-two eyes of 38 Japanese AZOOR patients (31 female and 7 male patients; mean age at first visit, 35.0 years; median follow-up duration, 31 months) were retrospectively collected: 31 untreated eyes with good visual acuity and 21 systemic corticosteroid-treated eyes with progressive visual acuity loss...
2015: PloS One
https://www.readbyqxmd.com/read/25653869/systemic-corticosteroids-therapy-in-the-management-of-acute-zonal-occult-outer-retinopathy
#17
San-Ni Chen, Chang-Hao Yang, Chung-May Yang
Purpose. To report the efficacy of systemic steroid in treating acute zonal occult outer retinopathy (AZOOR). Methods. Retrospective study of 9 consecutive patients of AZOOR, who received systemic steroid therapy in Changhua Christian Hospital from 2005 to 2013, is presented. The duration of therapy was at least 3 months. Patients were evaluated with best corrected visual acuity (BCVA), optical coherence tomography (OCT), fluorescein angiography (FA), indocyanine green angiography (ICG), visual field test, and electroretinography (ERG)...
2015: Journal of Ophthalmology
https://www.readbyqxmd.com/read/25390985/unilateral-cone-dysfunction-as-a-manifestation-of-acute-zonal-occult-outer-retinopathy
#18
Shigeki Machida, Junya Kizawa, Takamitsu Fujiwara, Ken-Ichi Murai, Eriko Sugawara, Noriko Imaizumi
PURPOSE: To report a patient with unilateral cone dysfunction (UCD) who later developed acute zonal occult outer retinopathy (AZOOR) in the contralateral eye. METHODS: A 19-year-old Japanese woman was referred complaining of decreased vision and photopsia of the left eye. Static perimetry, full-field electroretinography (ERG), and multifocal ERGs (mfERGs) were performed to evaluate her visual functions. She returned 9 months later with visual field defect and photopsia in the right eye...
2007: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/25390984/choroidal-neovascularization-in-peripapillary-acute-zonal-occult-outer-retinopathy
#19
Salomon Y Cohen, Lee M Jampol
BACKGROUND: Acute zonal occult outer retinopathy (AZOOR) is a disease of unknown etiology in young or middle-aged patients that is characterized by acute loss of one or more zones of outer retinal function, photopsia, minimal initial ophthalmoscopic changes, and electroretinographic abnormalities. AZOOR may represent part of the spectrum of a single disease, the so-called AZOOR complex. In contrast with most other ocular diseases that may be part of this AZOOR complex, AZOOR has not, to our knowledge, been reported in association with choroidal neovascularization (CNV)...
2007: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/25356549/changes-in-outer-retinal-microstructures-during-six-month-period-in-eyes-with-acute-zonal-occult-outer-retinopathy-complex
#20
Yoshitsugu Matsui, Hisashi Matsubara, Shinji Ueno, Yasuki Ito, Hiroko Terasaki, Mineo Kondo
PURPOSE: To study the changes in the outer retinal microstructures during a six month period after the onset of acute zonal occult outer retinopathy (AZOOR)-complex by spectral-domain optical coherence tomography (SD-OCT). METHODS: Seventeen eyes of 17 patients with the AZOOR-complex were studied. The integrity of the external limiting membrane (ELM), ellipsoid zone (EZ; also called the inner/outer segment junction), and interdigitation zone (IDZ; also called the cone outer segment tips) were evaluated in the SD-OCT images obtained at the initial visit and at six months...
2014: PloS One
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