keyword
MENU ▼
Read by QxMD icon Read
search

Vogt Koyanagi Harada

keyword
https://www.readbyqxmd.com/read/29023176/induction-of-vogt-koyanagi-harada-disease-by-interferon-alpha-and-ribavirin-treatment-in-patients-with-hepatitis-c-a-case-report-and-review-of-the-literature
#1
Jialiang Duan, Yang Wang, Danyan Liu, Jingxue Ma
PURPOSE: To describe a case of Vogt-Koyanagi-Harada disease (VKH) presenting in a hepatitis C patient after interferon-alpha (IFN-α) and ribavirin treatment. METHODS: A retrospective review of our patient and a review of the published literature. RESULTS: A 59 year-old man developed VKH after the four months of IFN-α and ribavirin therapy for hepatitis C. The patient's VKH was controlled by systemic corticosteroids. The relationship between VKH and IFN-α is discussed based on the published literature...
October 12, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29020488/unilateral-ocular-manifestations-of-vogt-koyanagi-harada-disease
#2
Edmund Tsui, Alexander Bottini, Quraish Ghadiali, Chandrakumar Balaratnasingam, Irene Barbazetto
PURPOSE: To describe a case of unilateral Vogt-Koyanagi-Harada (VKH) disease and associated multimodal imaging. METHODS: Retrospective case report. RESULTS: A 50-year-old Hispanic male presented with three days of painless decreased vision in his left eye, headache, and decreased hearing. His visual acuity was 20/20 in the right eye and counting fingers in the left eye. Examination of his right eye was unremarkable. Funduscopic examination of his left eye revealed multiple serous retinal detachments...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28984712/acute-angle-closure-secondary-to-tubercular-choroidal-granuloma
#3
Sushmita Kaushik, Ramandeep Singh, Atul Arora, Gunjan Joshi, Kusum Sharma, Basavraj Tigari
Acute angle closure is usually thought to be secondary to pupillary block which is relieved by laser iridotomy. Anterior rotation of the ciliary body at the scleral spur following development of an inflammatory cilio-choroidal detachment may result in a presentation of acute angle closure. It is imperative to recognize this condition correctly, because the management is with cycloplegics and anti-inflammatory drugs, which is diametrically opposite to the treatment of primary angle closure. More importantly, it has been reported as a consequence of serious systemic disease such as HIV infection and Vogt Koyanagi Harada(VKH) syndrome...
September 3, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28983414/anti-tnf%C3%AE-therapy-and-switching-in-severe-uveitis-related-to-vogt-koyanagi-harada-syndrome
#4
Bryan Josue Flores Robles, Juan Blanco-Madrigal, Abel Alejandro Sanabria Sanchinel, Dixie Huntley Pascual, Rosario Demetrio-Pablo, Ricardo Blanco
The study aimed to describe the effectiveness of switching the anti-TNFα agent when an acceptable clinical response has not been obtained with the first anti-TNFα agent in patients with uveitis in VKH syndrome. Patients diagnosed with VKH syndrome being evaluated from the uveitis unit of a single tertiary hospital from January 1, 2000, to October 30, 2015. Patients who presented uveitis with an inadequate response to a first anti-TNFα and required switching to a second anti-TNFα were selected. Complete clinical response was assumed in patients whose visual acuity was normal and those who showed absence of inflammatory findings (inflammatory cells in the anterior chamber and vitritis) or absence of macular thickening in upon OCT...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28979622/-vitiligo-revealing-vogt-koyanagi-harada-disease
#5
Mohamed El Amraoui, Youssef Zemmez, Ahmed Bouhamidi, Rachid Frikh, Naoufal Hjira, Mohammed Boui
Vitiligo is a chronic auto-immune skin disease, often associated or discovers other autoimmune pathologies. His association with Ophthalmological type pan uveitis and/or neurological type of meningitis and/or inner ear type of hearing loss determines the disease or Vogt -Koyanagi-Harada syndrome (VKH). We related the case of a young woman who consulted for recurrent uveitis for a year, and it was only with the onset of vitiligo lesions that VKH disease diagnosis was discussed and confirmed.
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28972425/lord-nelson-s-1758-1805-left-eye
#6
William Pryse-Phillips
Following the loss of his right eye at Calvi in 1794, Lord Nelson suffered increasing left-sided visual loss, here considered most likely to have been due to the ocular inflammatory condition 'sympathetic ophthalmia'. It is also argued that his succeeding episodes of violent headaches with nausea and prostration, and possible depigmentation of hair, reflected the development of an uveomeningoencephalitic syndrome akin to that of Vogt-Koyanagi-Harada disease, which is best regarded as the same condition with a different aetiology...
January 1, 2017: Journal of Medical Biography
https://www.readbyqxmd.com/read/28972028/microrna-20a-5p-suppresses-il-17-production-by-targeting-osm-and-ccl1-in-patients-with-vogt-koyanagi-harada-disease
#7
Rui Chang, Shenglan Yi, Xiao Tan, Yang Huang, Qingfeng Wang, Guannan Su, Chunjiang Zhou, Qingfeng Cao, Gangxiang Yuan, Aize Kijlstra, Peizeng Yang
AIM: To elucidate the role of microRNA-20a-5p (miR-20a-5p) in the pathogenesis of Vogt-Koyanagi-Harada (VKH) disease. METHODS: Quantitative real-time PCR was used to quantify miR-20a-5p expression in CD4(+) T cells from patients with active VKH and normal controls. The promoter methylation status of miR-20a-5p was detected by bisulfite sequencing PCR. Targets were evaluated by a luciferase reporter assay. The functional effects of miR-20a-5p on CD4(+) T cells from patients with active VKH were assessed by upregulation or downregulation of its expression using liposomes...
September 28, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28914578/the-choroidal-vascularity-index-decreases-and-choroidal-thickness-increases-in-vogt-koyanagi-harada-disease-patients-during-a-recurrent-anterior-uveitis-attack
#8
Shulin Liu, Liping Du, Qingyun Zhou, Qi Zhang, Ke Hu, Jian Qi, Liang Liang, Chunjiang Zhou, Aize Kijlstra, Peizeng Yang
PURPOSE: To measure changes in the choroidal vascularity index (CVI) in chronic Vogt-Koyanagi-Harada (VKH) disease during a recurrent anterior uveitis attack. METHODS: Forty VKH patients and 40 normal controls were included in this study. Choroidal images were recorded before and during a recurrent anterior uveitis attack, as well as after appropriate treatment. CVI was measured by the binarization technique using ImageJ software (Bethesda, MD). RESULTS: The CVI was 0...
September 15, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28910557/vogt-koyanagi-harada-syndrome-in-a-group-of-patients-in-two-ophthalmology-referral-centers-in-bogot%C3%A3-colombia
#9
Carol L Guayacán, Brahyan Galindo-Mendez, Alejandra de-la-Torre
PURPOSE: To describe the clinical presentation of Vogt-Koyanagi-Harada (VKH) syndrome in a group of patients in Colombia. METHODS: Retrospective review of 2638 medical records of patients with uveitis in two centers during 17 years. RESULTS: A total of 25 patients with uveitis were diagnosed with VKH syndrome (0.95%), 23 patients were included in the data analysis (0.87%), 78.3% females, and mean age of diagnosis was 37 years (SD ± 29)...
September 14, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28905833/unusual-case-of-vitiligo-reversal-in-vogt-koyanagi-harada-syndrome
#10
Praveen Subudhi, Zahiruddin Khan, B Nageswar Rao Subudhi, Silla Sitaram
No abstract text is available yet for this article.
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28868031/optical-coherence-tomography-angiography-employing-a-novel-technique-for-investigation-in-vogt-koyanagi-harada-disease
#11
Panagiotis Giannakouras, Konstantinos Andreanos, Barbara Giavi, Andreas Diagourtas
PURPOSE: To report a case of Vogt-Koyanagi-Harada (VKH) disease and describe the imaging findings by means of optical coherence tomography angiography (OCTA). METHODS: Medical and ophthalmological history, ophthalmological examination, laboratory evaluation, B-scan ultrasonography, fluorescein and indocyanine angiography, and optical coherence tomography (OCT) were performed at baseline, as well as OCTA. RESULTS: A 50-year-old healthy female presented with decreased vision in both eyes...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28863408/polarization-sensitive-optical-coherence-tomographic-documentation-of-choroidal-melanin-loss-in-chronic-vogt-koyanagi-harada-disease
#12
Masahiro Miura, Shuichi Makita, Yoshiaki Yasuno, Rintaro Tsukahara, Yoshihiko Usui, Narsing A Rao, Yasushi Ikuno, Sato Uematsu, Tetsuya Agawa, Takuya Iwasaki, Hiroshi Goto
Purpose: Vogt-Koyanagi-Harada (VKH) disease is a systemic autoimmune disorder that affects organs with melanocytes. The sunset glow fundus (SGF) in VKH disease was evaluated with polarization-sensitive optical coherence tomography (PS-OCT). Methods: The study involved 28 eyes from 14 patients with chronic VKH disease, 21 eyes from 21 age-matched controls, and 22 eyes from 22 high-myopic patients with a tessellated fundus. VKH eyes were grouped into sunset or non-sunset groups on the basis of color fundus images...
September 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28846771/association-of-a-pdcd1-polymorphism-with-sympathetic-ophthalmia-in-han-chinese
#13
Jing Deng, Jiayue Hu, Handan Tan, Guannan Su, Qingfeng Cao, Xinyue Huang, Aize Kijlstra, Peizeng Yang
Purpose: Several studies have shown that sympathetic ophthalmia (SO) and Vogt-Koyanagi-Harada (VKH) disease possess many similarities concerning their clinical manifestations. The aim of this study was to investigate whether single nucleotide polymorphisms that have been shown to be associated with VKH disease in earlier studies may also be associated with SO. Methods: There were 114 SO patients and 1230 healthy controls included in a case-control study, whereby 24 VKH-related single nucleotide polymorphisms (SNPs) were tested...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28845331/atypical-central-serous-chorioretinopathy
#14
Zafer Cebeci, Merih Oray, Şerife Bayraktar, İlknur Tuğal-Tutkun, Nur Kır
Bullous central serous chorioretinopathy (CSCR) is a rare variant of CSCR characterized by severe serous retinal detachment which especially involves the inferior quadrants. Corticosteroid therapy administered for systemic or ocular misdiagnoses may induce and exacerbate CSCR. The purpose of this study was to report diagnosis and treatment results of an unusual case of bullous CSCR induced by systemic and periocular corticosteroid therapy received at another medical center due to a misdiagnosis of Vogt-Koyanagi-Harada disease...
August 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28795548/-vogt-koyanagi-harada-syndrome
#15
A-C Chapelle, E Duchateau, B Locht
We present the case of a patient who had a decrease of the visual acuity associated with headaches, diagnosed as vogt-koyanagi-harada syndrome. This is a rare multisystemic pathology that affects organs with high concentration of melanocytes. This syndrome needs to be identified on time as corticotherapy has to be administrated urgently. This paper also summarizes the literature on this disease.
July 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28761327/expression-and-role-of-interleukin-9-in-vogt-koyanagi-harada-disease
#16
Zhixi Peng, Shaoqiu Jiang, Mingxing Wu, Xiyuan Zhou, Qian Wang
PURPOSE: Vogt-Koyanagi-Harada (VKH) disease is a systemic autoimmune disease that can lead to blindness. This study was designed to investigate whether interleukin (IL)-9 plays a role in the development of VKH disease. METHODS: IL-9, IL-17, and interferon (IFN)-γ levels, present in the supernatants of cultured peripheral blood mononuclear cells (PBMCs) and CD4+T cells, were assessed with enzyme-linked immunosorbent assay. IL-9 mRNA expression in PBMCs was measured with real-time quantitative PCR...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28752697/clinical-features-of-pregnancy-associated-retinal-and-choroidal-diseases-causing-acute-visual-disturbance
#17
Young Joo Park, Kyu Hyung Park, Se Joon Woo
PURPOSE: To report clinical features of patients with retinal and choroidal diseases presenting with acute visual disturbance during pregnancy. METHODS: In this retrospective case series, patients who developed acute visual loss during pregnancy (including puerperium) and visited a tertiary hospital from July 2007 to June 2015, were recruited by searching electronic medical records. Patients were categorized according to the cause of visual loss. Clinical features and required diagnostic modalities were analyzed in the retinal and choroidal disease group...
August 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28700251/choroidal-and-retinal-anatomical-responses-following-systemic-corticosteroid-therapy-in-vogt-koyanagi-harada-disease-using-swept-source-optical-coherence-tomography
#18
Durgasri Jaisankar, Rajiv Raman, Hitesh R Sharma, Neha Khandelwal, Muna Bhende, Rupesh Agrawal, Sridharan Sudharshan, Jyotirmay Biswas
PURPOSE: To assess structural changes in retina and choroid after systemic corticosteroid therapy in Vogt-Koyanagi-Harada (VKH) disease using swept-source optical coherence tomography (SS-OCT). METHODS: SS-OCT was conducted before treatment and during first-month follow-up in 16 eyes treated with systemic corticosteroids for active VKH. Retina was divided into five zones depending on pretreatment choroidal thickness (CT) of <100, >100 to <200, >200 to <300, >300 to <400 and >400μm, and changes in retinal thickness and CT after treatment in these zones were compared with baseline...
July 12, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28695542/wide-field-fluorescein-and-indocyanine-green-angiography-findings-in-the-eyes-with-vogt-koyanagi-harada-disease
#19
Ryo Kurobe, Yoshio Hirano, Naomi Niwa, Kazuhiko Sugitani, Tsutomu Yasukawa, Munenori Yoshida, Yuichiro Ogura
BACKGROUND: The purpose of this study is to report wide-field angiography findings before and after steroid therapy in a case with bilateral Vogt-Koyanagi-Harada (VKH) disease. RESULTS: A 44-year-old woman presented with bilateral blurred vision and metamorphopsia accompanied by symptoms of headache and tinnitus. The baseline best-corrected visual acuity was 20/20 in both eyes. Ophthalmic examination revealed a shallow anterior chamber and panuveitis accompanied by multiple serous retinal detachments in both eyes and ciliochoroidal detachments in the left eye...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28678751/association-between-cd40-rs1883832-and-immune-related-diseases-susceptibility-a-meta-analysis
#20
Jiaxuan Qin, Jinchun Xing, Rongfu Liu, Bin Chen, Yuedong Chen, Xuan Zhuang
BACKGROUND/OBJECTIVE: It has been reported that CD40 rs1883832 might be associated with immune-related diseases susceptibility. Owing to mixed and inconclusive results, we conducted a meta-analysis of case-control studies to summarize and clarify this association.Methods/main results: A systematic search of studies on the association between CD40 rs1883832 and immune-related diseases susceptibility was conducted in databases. Odds ratios and 95% confidence intervals were used to pool the effect size...
June 28, 2017: Oncotarget
keyword
keyword
79841
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"