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https://www.readbyqxmd.com/read/29665013/planhab-hypoxia-does-not-worsen-the-impairment-of-skeletal-muscle-oxidative-function-induced-by-bed-rest-alone
#1
Desy Salvadego, Michail E Keramidas, Roger Kölegård, Lorenza Brocca, Stefano Lazzer, Irene Mavelli, Jörn Rittweger, Ola Eiken, Igor B Mekjavic, Bruno Grassi
KEY POINTS: Superposition of hypoxia on 21 day bed rest did not worsen the impairment of skeletal muscle oxidative function induced by bed rest alone. A significant impairment of maximal oxidative performance was identified downstream of cardiovascular O2 delivery, involving both the intramuscular matching between O2 supply and utilization and mitochondrial respiration. These chronic adaptations appear to be relevant in terms of exposure to spaceflights and reduced gravity habitats (Moon or Mars), as characterized by low gravity and hypoxia, in patients with chronic diseases characterized by hypomobility/immobility and hypoxia, as well as in ageing...
April 17, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29663541/eccentric-exercise-increases-circulating-fibroblast-activation-protein-but-not-bioactive-fibroblast-growth-factor-21-in-healthy-humans
#2
Biraj Parmar, Jo E Lewis, Ricardo J Samms, Francis J P Ebling, Christine C Cheng, Andrew C Adams, Joanne Mallinson, Scott Cooper, Tariq Taylor, Reza Ghasemi, Francis B Stephens, Kostas Tsintzas
NEW FINDINGS: What is the central question of this study? The role of FGF21 as an exercise-induced myokine remains controversial. The aim of this study was to determine whether eccentric exercise would augment the release of FGF21 and/or its regulatory enzyme Fibroblast Activation Protein (FAP) from skeletal muscle tissue into the systemic circulation of healthy human volunteers. What is the main finding and its importance? Eccentric exercise does not release total or bioactive FGF21 from human skeletal muscle...
April 16, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29663478/superb-microvascular-imaging-of-the-median-nerve-in-carpal-tunnel-syndrome-an-electrodiagnostic-and-ultrasonographic-study
#3
Ali Yavuz Karahan, Serdar Arslan, Banu Ordahan, Suleyman Bakdik, Timur Ekiz
OBJECTIVE: To evaluate intraneural blood flow of the median nerve using superb microvascular imaging (SMI) and power Doppler ultrasonography (PDUS), and to examine their correlation with electroneuromyography in patients with carpal tunnel syndrome (CTS). METHODS: A cross-sectional survey was used, and the study was conducted in the research unit of a training and research hospital. Patients diagnosed with CTS according to electroneuromyography studies were included in the study...
April 16, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29659999/increased-body-mass-index-associated-with-reduced-risk-of-delayed-cerebral-ischemia-and-subsequent-infarction-after-aneurysmal-subarachnoid-hemorrhage
#4
Lorenzo Rinaldo, Alejandro A Rabinstein, Giuseppe Lanzino
BACKGROUND: Increased body mass index (BMI) may be protective against cerebral ischemia in certain clinical contexts. OBJECTIVE: To investigate whether increased BMI was associated with delayed cerebral ischemia (DCI) and subsequent infarction after aneurysmal subarachnoid hemorrhage (aSAH). METHODS: We retrospectively reviewed the clinical course of patients presenting to our institution for management of aSAH. Patient were segregated according to BMI< or ≥29...
April 4, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29658370/changes-in-endothelial-function-arterial-stiffness-and-blood-pressure-in-pregnant-women-after-consumption-of-high-flavanol-and-high-theobromine-chocolate-a-double-blind-randomized-clinical-trial
#5
Asma Babar, Emmanuel Bujold, Vicky Leblanc, Élise Lavoie-Lebel, Joalee Paquette, Laurent Bazinet, Simone Lemieux, Isabelle Marc, Belkacem Abdous, Sylvie Dodin
OBJECTIVES: The aim of this 2-group, parallel, double blind single-centre RCT was to evaluate the acute and chronic impacts of high flavanol high theobromine (HFHT) chocolate consumption on endothelial function, arterial stiffness and blood pressure (BP) in women at risk of preeclampsia. METHODS: 131 pregnant women considered at risk of preeclampsia based on uterine artery Doppler ultrasound were divided into two groups (HFHT or low flavanol and theobromine chocolate (LFLT)...
April 16, 2018: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/29657758/temporal-and-spatial-changes-in-wall-shear-stress-during-atherosclerotic-plaque-progression-in-mice
#6
R Xing, A M Moerman, Y Ridwan, M J Daemen, A F W van der Steen, F J H Gijsen, K van der Heiden
Wall shear stress (WSS) is involved in atherosclerotic plaque initiation, yet its role in plaque progression remains unclear. We aimed to study (i) the temporal and spatial changes in WSS over a growing plaque and (ii) the correlation between WSS and plaque composition, using animal-specific data in an atherosclerotic mouse model. Tapered casts were placed around the right common carotid arteries (RCCA) of ApoE-/- mice. At 5, 7 and 9 weeks after cast placement, RCCA geometry was reconstructed using contrast-enhanced micro-CT...
March 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29657604/the-role-of-intestinal-ultrasound-in-diagnostics-of-bowel-diseases
#7
REVIEW
Magdalena Andrzejewska, Marian Grzymisławski
Intestinal ultrasound is a safe and inexpensive method that allows visualisation of the gastrointestinal tract and detection of abnormalities. This examination involves the use of two different ultrasound transducers: a low-frequency convex probe and high-frequency linear probe. When needed, the performance of these methods can be enhanced by the use of contrast media or Doppler techniques. Intestinal ultrasound is mostly utilised for the diagnosis and follow-up of patients with inflammatory bowel diseases, helping to avoid frequent use of invasive and expensive diagnostic procedures and leading to early implementation of suitable treatment...
2018: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29657139/power-doppler-ultrasound-evaluation-of-peripheral-joint-entheses-tendon-and-bursa-abnormalities-in-psoriatic-patients-a-clinical-study
#8
Yuanjiao Tang, Yujia Yang, Xi Xiang, Liyun Wang, Lingyan Zhang, Li Qiu
OBJECTIVE: To evaluate the prevalence rates of peripheral joint, enthesis, tendon, and bursa abnormalities by power Doppler (PD) ultrasonic examination in patients with psoriatic arthritis (PsA), psoriatic patients without clinical signs of arthritis (non-PsA psoriasis group), and healthy individuals, to detect subclinical PsA. METHODS: A total of 253 healthy volunteers, 242 non-PsA psoriatic patients, and 86 patients with PsA were assessed by 2-dimensional and power Doppler (PD) ultrasound...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29652653/role-of-foetal-umbilical-artery-doppler-on-prediction-of-adverse-pregnancy-outcomes-in-patients-with-systemic-lupus-erythematosus
#9
Zhongping Zhan, Yanfeng Zhan, Minxi Lao, Xiuyan Yang, Xiaodong Wang, Dongying Chen
OBJECTIVES: To investigate the foetal outcomes and examine the predictive value of the third-trimester umbilical artery Doppler in systemic lupus erythematosus (SLE) pregnancies. METHODS: Data of 180 pregnancies in 175 SLE patients from Jan 2007 to Jan 2017 were analysed retrospectively. Pulsatility index (PI), resistance index (RI), and systolic/diastolic ratio (S/D) of the umbilical artery flow velocity data were monitored by Doppler ultrasound. RESULTS: One or more composite adverse pregnancy outcomes (APOs) occurred in 46...
April 13, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29650457/-non-palpable-testicular-tumors-in-adults-a-management-based-on-imaging-issue-from-the-french-urologic-association-genital-cancer-committee-s-edit
#10
L Rocher, L Feretti, P Camparo, P H Savoie, N Morel-Journel, T Murez, P Sebe, A Flechon, A Méjean, X Durand
BACKGROUND: Help in management of non-palpable testicular tumors. French Urologic Association Genital cancer committee's Edit. OBJECTIVES: To review their characterization at imaging findings of non-palpable testicular tumors. DOCUMENTARY SOURCES: Literature review (PubMed, Medline) of urological and radiological studies dealing with testicular tumors using keywords: non-palpable/incidental testicular tumors; color Doppler ultrasound; US elastography; magnetic resonance imaging; contrast enhanced sonography; partial surgery...
April 9, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29649559/ultrafast-doppler-for-neonatal-brain-imaging
#11
REVIEW
Charlie Demene, Jérôme Mairesse, Jérôme Baranger, Mickael Tanter, Olivier Baud
The emergence of functional neuroimaging has dramatically accelerated our understanding of the human mind. The advent of functional Magnetic Resonance Imaging paved the way for the next decades' major discoveries in neuroscience and today remains the "gold standard" for deep brain imaging. Recent improvements in imaging technology have been somewhat limited to incremental innovations of mature techniques instead of breakthroughs. Recently, the use of ultrasonic plane waves transmitted at ultrafast frame rates was shown to highly increase Doppler ultrasound sensitivity to blood flows in small vessels in rodents...
April 9, 2018: NeuroImage
https://www.readbyqxmd.com/read/29649509/cybersickness-related-changes-in-brain-hemodynamics-a-pilot-study-comparing-transcranial-doppler-and-near-infrared-spectroscopy-assessments-during-a-virtual-ride-on-a-roller-coaster
#12
Alireza Mazloumi Gavgani, Rachel H X Wong, Peter R C Howe, Deborah M Hodgson, Frederick R Walker, Eugene Nalivaiko
Our aim was to assess cerebral blood flow changes during cybersickness. Transcranial Doppler (TCD) ultrasound and near infrared spectroscopy (NIRS) were used separately in two independent experiments. In both studies, a 15-min virtual roller coaster ride was used as a provocative visual stimulus. Subjective nausea ratings were obtained at 1 min intervals. The TCD study was performed in 14 healthy subjects (8 males and 6 females); in this study we also measured heart rate and arterial pressure. In a separate study a 52-channel NIRS device (Hitachi ETG-4000) was used to monitor activated brain regions by measuring oxy-hemoglobin (HbO2) concentration in 9 healthy subjects (4 male, 5 females)...
April 9, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29644030/proof-of-concept-liver-splitting-during-normothermic-machine-perfusion
#13
Barney T F Stephenson, Glenn K Bonney, Richard W Laing, Ricky H Bhogal, Francesca Marcon, Desley A H Neil, M Thamara P R Perera, Simon C Afford, Hynek Mergental, Darius F Mirza
Introduction: Despite utilizing extended criteria donors, there remains a shortage of livers for transplantation. No data exists on splitting donor livers with concurrent NMP-L. Methods: A liver recovered from a donor after circulatory death was subjected to NMP-L using a red cell based fluid. During NMP-L, a 'classical' left lateral + right trisegmentectomy split was performed using an integrated bipolar/ultrasonic device. After splitting, blood flow was confirmed using Doppler ultrasound in each lobe...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29642694/integrated-quadruple-stress-echocardiography
#14
Eugenio Picano, Doralisa Morrone, Maria C Scali, Alda Huqi, Katia Coviello, Quirino Ciampi
Stress Echocardiography (SE) is an established diagnostic technique. For 40 years, the cornerstone of the technique has been the detection of regional wall motion abnormalities (RWMA), due to the underlying physiologically-relevant epicardial coronary artery stenosis. In the last decade, three new parameters (more objective than RWMA) have shown the potential to integrate and comple- ment RWMA: 1- B-lines, also known as ultrasound lung comets, as a marker of extra-vascular lung water, measured using lung ultrasound with the 4-site simplified scan symmetrically of the antero- lateral thorax on the third intercostal space, from mid-axillary to anterior axillary and mid- clavicular line; 2-left ventricular contractile reserve (LVCR), assessed as the peak stress/rest ratio of left ventricular force, also known as elastance (systolic arterial pressure by cuff sphygmomanome- ter/end-systolic volume from 2D echocardiography); 3- coronary flow velocity reserve (CFVR) on left anterior descending coronary artery, calculated as peak stress/rest ratio of diastolic peak flow velocity assessed using pulsed-wave Doppler...
April 11, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29626976/chronic-histiocytic-intervillositis-clinical-biochemical-and-radiological-findings-an-observational-study
#15
Lawrence Koby, Sarah Keating, Ann Kinga Malinowski, Rohan D'Souza
INTRODUCTION: Chronic histiocytic intervillositis (CHI) of the placenta although rare, has a high recurrence rate, is associated with serious adverse pregnancy outcomes and has no available treatment. This study aims to determine clinical, biochemical and radiological factors associated with CHI, to guide management of subsequent pregnancies. METHODS: This retrospective observational study included consecutive cases with a histopathologic diagnosis of CHI after 18 weeks of gestation, between 2001 and 2014, and no controls...
April 2018: Placenta
https://www.readbyqxmd.com/read/29624144/pilot-study-of-intracranial-venous-physiology-in-craniosynostosis
#16
Martijn J Cornelissen, Robbin de Goederen, Priya Doerga, Iris Cuperus, Marie-Lise van Veelen, Maarten Lequin, Paul Govaert, Irene M J Mathijssen, Jeroen Dudink, Robert C Tasker
OBJECTIVE In addition to craniocerebral disproportion, other factors, such as Chiari malformation type I, obstructive sleep apnea, and venous outflow obstruction, are considered to have a role in the occurrence of intracranial hypertension in craniosynostosis. This pilot study examined cerebral venous flow velocity to better characterize the complex intracranial venous physiology of craniosynostosis. METHODS The authors performed a prospective cohort study of craniosynostosis patients (n = 34) referred to a single national (tertiary) craniofacial unit...
April 6, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29622968/atherosclerosis-in-chronic-hepatitis-c-virus-patients-with-and-without-liver-cirrhosis
#17
Ashraf Abd El-Khalik Barakat, Fatma Mohammad Nasr, Amna Ahmed Metwaly, Sherif Morsy, Mervat Eldamarawy
Background: Chronic Hepatitis C virus (HCV) infection and liver cirrhosis may be associated with atherosclerosis and coronary artery disease (CAD). There are two phases to atherosclerosis, Subclinical and Clinical. Assessment of atherosclerosis may be started at its Subclinical phase by the evaluation of Epicardial Fat Thickness (EpFT) and Carotid Intima Thickness (CIMT). Aim of the study: The aim of the study was to evaluate Clinical and Subclinical atherosclerosis in chronic HCV patients with and without liver cirrhosis by evaluating CIMT and EpFT and correlating the results with Child-Pugh functional scoring of cirrhosis as well as with ultrasound and laboratory parameters that define the severity of liver disease...
June 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29621824/true-or-false-umbilical-cord-knot-differentiation-via-3d-4d-color-doppler-ultrasound
#18
Eberhard Merz, Sonila Pashaj
No abstract text is available yet for this article.
April 2018: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29621786/relationship-between-the-von-willebrand-factor-plasma-concentration-and-ultrasonographic-doppler-findings-in-pregnancies-complicated-by-hypertensive-disorders-a-pilot-study
#19
Agata Szpera-Gozdziewicz, Tomasz Gozdziewicz, Maciej Boruczkowski, Grzegorz Dworacki, Grzegorz H Breborowicz
BACKGROUND/AIMS: Recent evidence suggests that impaired cytotrophoblast proliferation and migration are major factors responsible for the development of hypertension in pregnancy. Studies report that von Willebrand factor (vWf) is a specific endothelial damage plasma marker. The aim of this study was to evaluate the relationship between vWf maternal plasma concentration and maternal and fetal Doppler flow measurements in pregnancies complicated by hypertension. It may provide additional insight into the pathophysiology of pregnancy-related hypertension and show the potential method for disease prevention and therapy...
April 5, 2018: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29620658/scrotal-paragonimiasis-in-adults-two-case-reports-and-review-of-literature
#20
Tiancai Liang, Guobiao Liang, Yang Du, Xin Wang, Yuanliang Wang, Anjian Chen, Zongping Chen, Jiang Du, Hao Li, Lang Yu
RATIONALE: Paragonimiasis is a parasitic disease caused by Paragonimus in the lungs; it can be divided into intrapulmonary type and extrapulmonary type. Adult patients with scrotal paragnonimus are rarely seen clinically and not widely reported in the literature. Here, we report 2 cases of scrotal paragonimiasis in adults and their treatment process. PATIENT CONCERNS: Two young males sought medical advice because of scrotal masses. Both patients had the previous history of eating uncooked river crabs and presented with palpable quasicircular nodules of about 1...
April 2018: Medicine (Baltimore)
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