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Multifocal choroiditis

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https://www.readbyqxmd.com/read/29787321/enhanced-depth-imaging-by-high-resolution-spectral-domain-optical-coherence-tomography-in-tubercular-multifocal-serpiginoid-choroiditis
#1
Bruttendu Moharana, Reema Bansal, Ramandeep Singh, Aman Sharma, Vishali Gupta, Amod Gupta
PURPOSE: To report the choroidal changes by enhanced depth imaging optical coherence tomography (EDI-OCT) in tubercular multifocal serpiginoid choroiditis (MSC). METHODS: Prospective study of 20 patients (23 eyes) with active MSC who underwent simultaneous fundus autofluorescence and EDI-OCT imaging at regular visits. RESULTS: Eyes with acute lesions demonstrated diffuse choroidal thickening at presentation, which decreased significantly as the lesions healed...
May 22, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29780913/cryptococcal-choroiditis-in-advanced-aids-with-clinicopathologic-correlation
#2
Christopher M Aderman, Ian R Gorovoy, Daniel L Chao, Michele M Bloomer, Anthony Obeid, Jay M Stewart
Purpose: To describe a case of disseminated cryptococcal meningitis with multifocal choroiditis and provide optical coherence tomography (OCT) findings correlated with described histopathology in a patient with advanced acquired immunodeficiency syndrome (AIDS). Observations: The patient was a 54-year-old man with AIDS who presented with dyspnea and headache followed by acute vision loss. OCT demonstrated a lesion with a small area of fluid that was limited by a more prominent and irregular external limiting membrane with underlying nodular choroidal thickening, mild RPE disorganization, and hyperreflectivity of the overlying photoreceptor layer...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29687336/clinical-efficacy-and-safety-of-current-interventions-for-choroidal-neovascularization-associated-with-rare-diseases-a-systematic-literature-review
#3
REVIEW
Natalie Bennett, Lokho John, Nishkarsh Likhar, Rumjhum Agrawal, Winfried M Amoaku
INTRODUCTION: The aim of this systematic literature review was to evaluate the efficacy and safety of interventions for the treatment of choroidal neovascularization (CNV) secondary to etiologies other than age-related macular degeneration and pathologic myopia. METHODS: Relevant randomized controlled trials (RCTs) and prospective observational studies were identified by searching MEDLINE, MEDLINE In-Process, EMBASE, and CENTRAL. RESULTS: The search identified 5 RCTs; no relevant observational studies were identified...
May 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29623252/intraocular-inflammation-in-a-case-of-bee-sting-injury
#4
Ekta Rishi, Pukhraj Rishi
A19-year-old man presented with decreased vision in the right eye following a bee sting injury, ten days back. Examination revealed conjunctival hyperemia at the site of the sting, anterior uveitis, vitritis, mild disc hyperemia, ocular hypotony, and striae at macula. Treatment was initiated elsewhere with topical antibiotics, steroid, and cycloplegic. Systemic steroids were added. Three weeks later, vitiritis resolved, intraocular pressure became normal and the vision improved from 20/60 to 20/20. However, a chorioretinal atrophy in the vicinity of the sting site was noted...
2018: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/29616508/an-efficacy-analysis-of-anti-vascular-endothelial-growth-factor-therapy-for-choroidal-neovascularization-secondary-to-multifocal-choroiditis-and-comparison-with-wet-age-related-macular-degeneration
#5
Lei Feng, Jiang-Hua Hu, Jie Chen, Xin Xie
OBJECTIVE: To evaluate the effect of anti-vascular endothelial growth factor (VEGF) on juxtafoveal choroidal neovascularization (CNV) secondary to multifocal choroiditis (MFC) and wet age-related macular degeneration (AMD). METHODS: In this retrospective, comparative study, 20 unique eyes with CNV were divided into two groups: 10 patients affected by MFC and 10 patients diagnosed with wet AMD. They all received local intravitreal (IVT) injections of ranibizumab, with 6 months of follow-up...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29595560/spironolactone-as-a-therapeutic-alternative-for-the-bullous-variant-of-central-serous-chorioretinopathy
#6
Eva C Ramos-Yau, Ediberto Muñoz-Domínguez, Silvia P Contreras-Mérida, Luis M Valencia-Londoño
PURPOSE: To report a case of the bullous variant of central serous chorioretinopathy successfully treated with spironolactone, a mineralocorticoid receptor antagonist. METHODS: Case report of a patient including fluorescein angiography, optical coherence tomography, and color fundus photography. RESULTS: Initially managed as a multifocal choroiditis, the use of oral and peribulbar corticoids worsened the serous retinal detachment. Taking in consideration this response, she was then diagnosed with a bullous variant of central serous chorioretinopathy and treated with 50 mg of spironolactone per day...
March 27, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29569477/optical-coherence-tomography-angiography-and-choroidal-neovascularization-in-multifocal-choroiditis-a-descriptive-study
#7
Cyril Dutheil, Jean-François Korobelnik, Marie-Noëlle Delyfer, Marie-Bénédicte Rougier
PURPOSE: To analyze the ability of optical coherence tomography angiography to identify choroidal neovascularization in multifocal choroiditis and to describe active and inactive choroidal neovascularization findings. METHODS: Retrospective study of consecutive patients with multifocal choroiditis and choroidal neovascularization examined between January and November 2016. In addition to usual exams, optical coherence tomography angiography (AngioPlex™ CIRRUS™ HD-OCT model 5000; Carl Zeiss Meditec, Inc...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29554812/clinical-applications-of-optical-coherence-tomography-angiography-what-we-have-learnt-in-the-first-3-years
#8
Salomon Y Cohen, Alexandra Miere, Sylvia Nghiem-Buffet, Franck Fajnkuchen, Eric H Souied, Sarah Mrejen
A review of the literature from 2014 to 2016 was conducted, focusing on the results of optical coherence tomography angiography in different chorioretinal diseases. In only 3 years, optical coherence tomography angiography has been shown to be an effective tool for diagnosing choroidal neovascularization complicating age-related macular degeneration, pathologic myopia, and inflammatory conditions. The technique has sometimes been considered superior to conventional multimodal imaging, for example, in choroidal neovascularization associated with chronic central serous chorioretinopathy or multifocal choroiditis...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29516050/multifocal-choroiditis-and-panuveitis-difficulties-in-diagnosis-and-treatment
#9
Neacșu Gheorghe Boricean, Oana Roxana Scripcă
We present the case of a 49-year-old patient who was treated with Aripriprazole in context of Paranoid Schizophrenia. The patient had a history of numerous Panuveitis recurrences for the left eye, which led to a marked decrease of the vision VA-NLP and was diagnosed with Multifocal Choroiditis and Panuveitis for the right eye. The examination revealed VA of 20/ 200 for right eye, keratic precipitates, and vitritis. Fundus aspect of the right eye showed multiple discrete, ovoid, yellowish-grey lesions at the posterior pole and periphery, optic disc oedema was present...
October 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29503956/multifocal-choroiditis-as-the-first-sign-of-systemic-sarcoidosis-associated-with-pembrolizumab
#10
Qu-Knafo Lise, Auregan-Giocanti Audrey
Purpose: To report a case of bilateral panuveitis with multifocal choroiditis associated with a systemic sarcoidosis unmasked by pembrolizumab. Case report: A 68-years old woman with a history of metastatic melanoma treated by pembrolizumab consulted for bilateral blurred vision. The ophthalmologic examination revealed a bilateral anterior uveitis with cells in the anterior chamber and granulomatous keratic precipitates, vitreous cells and multifocal choroiditis confirmed by indocyanine green angiography...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29493862/multiple-ocular-developmental-defects-in-four-closely-related-alpacas
#11
Kelly E Knickelbein, David J Maggs, Christopher M Reilly, Kathryn L Good, Juliet R Gionfriddo
OBJECTIVE: To describe the clinical, gross pathologic, and histopathologic findings for a visually impaired 5.8-year-old female alpaca with multiple ocular abnormalities, as well as the clinical findings for three closely related alpacas. ANIMALS STUDIED: Four alpacas. PROCEDURES: Ophthalmic examination was performed on a 16-month-old female alpaca following observation of visual impairment while hospitalized for an unrelated illness. Following acute systemic decline and death 4...
March 1, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29402251/varicella-zoster-virus-associated-chorioretinitis-a-case-report
#12
Joo Yeon Kim, Ji Hwan Lee, Christopher Seungkyu Lee, Sung Chul Lee
BACKGROUND: Chorioretinitis is an unusual form of varicella zoster virus (VZV)-associated uveitis, and no report has described VZV-associated chorioretinitis using serial optical coherence tomography (OCT) images obtained during the course of resolution. CASE PRESENTATION: A 61-year-old woman presented with acute, unilateral vision loss in her right eye. Her visual acuity was count fingers in the right eye and 16/20 in the left eye, and she exhibited skin vesicles on her right forehead...
February 5, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29380793/quantitative-polymerase-chain-reaction-analysis-of-serpiginous-choroiditis-with-biopsy-proven-testicular-tuberculosis
#13
Abhinav Dhami, Ranju Kharel Sitaula, Jyotirmay Biswas
We report a case of a 47-year-old male patient presenting with diminution of vision in the left eye. The left eye fundus showed yellowish lesions with indistinct geographical margin extending over the posterior pole just abutting the macula, suggestive of diffuse choroiditis. The patient gave a history of testicular swelling for the past 2 years. Aqueous tap for polymerase chain reaction analysis was positive for IS6110 mycobacterial tuberculosis (TB) genome, and a biopsy of testicular sac was suggestive of tubercular epididymitis...
February 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29344499/unilateral-multifocal-choroidal-melanoma
#14
Debarshi Mustafi, Bertil Damato, Jesse L Berry
We report a case of multifocal choroidal melanoma in the same eye, separated in presentation by 20 years. A 57-year-old Caucasian male initially presented with a choroidal melanoma of the right eye that was treated with transpupillary thermotherapy. Due to recurrence, the patient underwent proton beam therapy with subsequent tumor regression. A second small choroidal lesion was noted in the right eye during his surveillance examinations that was closely monitored and demonstrated stable dimensions and features suggestive of a choroidal nevus...
December 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29304271/blau-jabs-syndrome-in-a-tertiary-ophthalmologic-center
#15
Heloisa Nascimento, Jacqueline M Sousa, Délia González Fernández, Gustavo H A Salomão, Elcio H Sato, Cristina Muccioli, Rubens Belfort
In a prospective case series of patients with Blau-Jabs syndrome (BJS) conducted in the Ophthalmology Department/Federal University of Sao Paulo, seven patients with clinical and ophthalmologic manifestations of the disease and a positive genetic test result for the presence of a mutation in the CARD15/NOD2 gene were followed for a minimal period of 1 year. All patients had uveitis, five had nummular corneal subepithelial opacities, and four had multifocal choroiditis. Oral prednisolone was administered to all patients; inflammation was controlled in six patients with at least one immunosuppressive drug...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29251664/long-term-observation-of-multifocal-metastatic-intraocular-carcinoid-with-acquired-iris-heterochromia
#16
Natalie Wolkow, Frederick A Jakobiec, Evangelos S Gragoudas
BACKGROUND/PURPOSE: To report a unique case of a pulmonary carcinoid tumor unilaterally metastatic to the iris and ciliary body and bilaterally to the choroid that was conservatively followed. METHODS: A 46-year-old woman presented with bilateral choroidal lesions and a left iris tumor. Ultrasound biomicroscopy disclosed a ciliary body component. A diagnosis of metastatic carcinoid tumor was made based on the clinical features. Rather than an excision, photodynamic therapy, or radiation treatment, as has been reported in all previous cases of carcinoid tumor metastatic to the iris, the patient was observed...
December 13, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29230338/optical-coherence-tomography-angiography-of-punctate-inner-choroidopathy
#17
Blake M Hampton, Christopher M Aderman, Harry W Flynn, Jayanth Sridhar
Purpose: To report a case of bilateral choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) visualized utilizing optical coherence tomography angiography (OCT-A). Methods: Case report. Results: A 29-year-old woman presented with new visual symptoms in both eyes. Fundoscopic exam revealed bilateral multifocal, small, well-defined lesions consistent with PIC. Optical coherence tomography demonstrated subretinal fluid and retinal pigment epithelium detachments (RPEDs) in both eyes...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29190170/the-role-of-dexamethasone-implant-in-the-management-of-tubercular-uveitis
#18
Aniruddha Agarwal, Sabia Handa, Kanika Aggarwal, Mansi Sharma, Ramandeep Singh, Aman Sharma, Rupesh Agrawal, Kusum Sharma, Vishali Gupta
PURPOSE: To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS: In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications such as cystoid macular edema (CME), vitritis, or paradoxical worsening in TB-related intermediate uveitis, retinal vasculitis, and multifocal serpiginoid choroiditis (MSC) was performed...
November 30, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29176533/idiopathic-multifocal-choroiditis-presenting-with-a-transient-peripapillary-white-ring
#19
Sarra Gattoussi, Quraish Ghadiali, Rosa Dolz-Marco, K Bailey Freund
PURPOSE: We describe with multimodal imaging the presentation and follow-up for a patient with idiopathic multifocal choroiditis and a transient peripapillary white ring. METHODS: Case report. RESULTS: A 39-year-old Asian woman was initially seen for an evaluation of lattice degeneration in 2015. Her medical history included Graves disease and psoriasis. Best-corrected visual acuity was 20/25 in her right eye and 20/25 in her left eye. Ultra-widefield fundus autofluorescence imaging showed a curvilinear hyperautofluorescent line in her right eye...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29152599/a-novel-clinical-sign-in-intraocular-tuberculosis-active-chorioretinitis-within-chorioretinal-atrophy
#20
Avinash Pathengay, Bhavik Panchal, Himadri Choudhury, Soumyava Basu, Nidhi Relhan, Harry W Flynn
Purpose: To report a novel clinical sign in patients with intraocular tuberculosis. The current study is an observational consecutive case series of patients diagnosed with intraocular tuberculosis managed at a tertiary eye care centre from June 1, 2012 to December 31, 2015. Observations: The diagnosis of intraocular tuberculosis was made in 6 patients based on ocular features suggestive of tuberculosis along with a positive tuberculin skin testing and chest X-ray consistent with tuberculosis...
September 2017: American Journal of Ophthalmology Case Reports
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