keyword
https://read.qxmd.com/read/38521148/edi-oct-as-an-auxiliary-examination-for-the-differential-diagnosis-of-bullous-csc-and-vogt-koyanagi-harada-a-case-report
#1
Yuanyuan Zhang, Chenwei Gui, Tianyu Wang, Jianhao Bai, Zhongqi Wan, Lei Gao, Qing Peng
A 46-year-old male patient visited our clinic with a complaint of blurred vision in the right eye accompanied by headache and insomnia. The fundus examination showed three bullous retinal detachments in the right eye. Considering the prodromal symptoms and other fundus characteristics such as vitreous cells in the posterior pole and multifocal fluorescence leakages on fundus fluorescein angiography (FFA), initial diagnosis was considered as Vogt-Koyanagi-Harada (VKH). However, oral glucocorticoids didn't improve patient's vision...
March 21, 2024: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/38518991/diagnostic-utility-of-quantiferon-gold-testing-in-patients-with-ocular-inflammation-in-a-low-endemic-tuberculosis-region
#2
JOURNAL ARTICLE
Julia Xia, Alan G Palestine, Amit K Reddy
PURPOSE: To evaluate the diagnostic value of QuantiFERON Gold (QFT-G) testing for ocular inflammation in a low prevalence tuberculosis (TB) area. DESIGN: Diagnostic utility analysis. METHODS: A review was performed for all uveitis patients who underwent QFT-G testing at the University of Colorado Eye Center from 2009-2022. Records were reviewed to assess QFT-G positivity rate and to identify which patients were tested for diagnostic purposes, defined as meeting the Standardization of Uveitis Nomenclature (SUN) criteria for tubercular uveitis (TBU): anterior uveitis with iris nodules, serpiginous-like choroiditis, choroidal nodule resembling a tuberculoma, multifocal choroiditis, or occlusive retinal vasculitis...
March 20, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38510631/a-rare-trifocal-presentation-of-a-choroid-plexus-papilloma-case-report-and-review-of-the-literature
#3
REVIEW
Senne Broekx, Mania De Praeter
INTRODUCTION: CPP's present as slow-growing intraventricular neoplasms arising from epithelium of choroid plexus. They account for approximately 0.5-4% of intracranial neoplasms in adults and children, respectively. A trifocal presentation is exceedingly rare. RESEARCH QUESTION: We describe the case of a trifocal presentation of a CPP and explored the importance of genetic analyses. MATERIAL AND METHODS: We present the case of an 18-year old adolescent who was treated for a fourth ventricular and suprasellar neoplasm...
2024: Brain Spine
https://read.qxmd.com/read/38437813/severe-recurrence-and-retinal-inflammatory-infiltration-after-cessation-of-immunosuppression-for-multifocal-choroiditis-and-panuveitis
#4
JOURNAL ARTICLE
Jeannette Ossewaarde-van Norel, Richard F Spaide
PURPOSE: To describe a severe recurrence of intraocular inflammation following the cessation of immunosuppression, previously administered for multifocal choroiditis and panuveitis (MCP). METHODS: Retrospective chart review. RESULTS: A 27-year-old woman with MCP initially was treated with intravenous and oral corticosteroids and photodynamic therapy because of an active macular neovascularization in both eyes. Mycophenolate was soon started and the recurrences during tapering of the oral corticosteroids in the first months were treated with periocular corticosteroids and anti-vascular endothelial growth factor injections as they became available...
March 4, 2024: Retinal Cases & Brief Reports
https://read.qxmd.com/read/38428557/an-automated-comparative-analysis-of-the-exudative-biomarkers-in-neovascular-age-related-macular-degeneration-the-rap-study-report-6
#5
JOURNAL ARTICLE
Bilal Haj Najeeb, Bianca S Gerendas, Gabor G Deak, Oliver Leingang, Hrvoje Bogunovic, Ursula Schmidt-Erfurth
PURPOSE: To explore the differences in volume and distribution of exudative biomarkers across macular neovascularization (MNV) types and subtypes using artificial intelligence (AI). DESIGN: Cross-sectional study. METHODS: We applied an AI-based analysis of 34.528 OCT b-scans of 281 (250 unifocal, 31 multifocal) MNV3, 55 MNV2, and 121 (30 polypoidal, 91 non-polypoidal) MNV1 treatment-naïve eyes. We compared the means (standard deviations) and heat maps of cystic intraretinal fluid (IRF), subretinal fluid (SRF), pigment epithelial detachments (PED) and hyperreflective foci (HRF) volumes, as well as retinal thickness (RT) among MNV (sub)types...
February 28, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38373901/efficacy-and-safety-of-intravitreal-injections-of-conbercept-for-the-treatment-of-idiopathic-choroidal-neovascularization
#6
JOURNAL ARTICLE
Gaixia Zhai, Yuanzhen Su, Shaopeng Wang, Hui Lu, Na Liu
BACKGROUND: To determine the efficacy and safety of intravitreally injected conbercept, a vascular endothelial growth factor receptor fusion protein, for the treatment of idiopathic choroidal neovascularization (ICNV). METHODS: This retrospective study analyzed outcomes in 40 patients (40 eyes) with ICNV who received intravitreal injections of conbercept 0.5 mg (0.05 ml) and were followed up for at least 12 months. All patients underwent full ophthalmic examinations, including best-corrected vision acuity (BCVA), intraocular pressure (IOP), slit-lamp examination, color fundus photography, optical coherence tomography angiography, multifocal electroretinogram, and fundus fluorescence angiography, if necessary, at baseline and after 1, 3, 6, and 12 months...
February 19, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38371246/impact-of-multifocal-gas-permeable-lens-designs-on-short-term-choroidal-response-axial-length-and-retinal-defocus-profile
#7
JOURNAL ARTICLE
Muteb Alanazi, Patrick Caroline, Amane Alshamrani, Maria Liu
AIM: To investigate the impact of multifocal gas permeable contact lens (MFGPCL) in various add power and distance/near area allocation on short-term changes of choroidal thickness (ChT), axial length (AL), and retinal defocus profile in young adults. METHODS: Seventeen young adults (2 males and 15 females; age 23.17±4.48y) were randomly assigned to wear two designs binocularly with a one-week washout period in between. Total of four MFGPCL designs were assessed...
2024: International Journal of Ophthalmology
https://read.qxmd.com/read/38357214/bilateral-cryptococcal-choroiditis-in-a-human-immunodeficiency-virus-infected-patient-a-case-report
#8
Sara Sanfilippo, Bastien Docquier, Paul Louis Schrooyen, Dorine Makhoul, Aurélie Le
INTRODUCTION: In this case report, we present a rare case of bilateral cryptococcal choroiditis following a diagnosis of meningitis in a 38-year-old woman with HIV. CASE PRESENTATION: A Colombian woman, newly diagnosed with HIV, presented with respiratory distress followed by meningeal syndrome. Further evaluation revealed cryptococcal meningitis caused by Cryptococcus neoformans , confirmed through cerebrospinal fluid analysis and brain magnetic resonance imaging...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38224927/immunomodulatory-treatment-vs-systemic-steroids-in-inflammatory-choroidal-neovascularization-secondary-to-idiopathic-multifocal-choroiditis
#9
JOURNAL ARTICLE
Matteo Airaldi, Davide Monteduro, Giovanni Tondini, Francesco Pichi, Luca De Simone, Elisa Cornish, Giuseppe Casalino, Federico Zicarelli, Marta Oldani, Giovanni Staurenghi, Peter McCluskey, Luca Cimino, Alessandro Invernizzi
PURPOSE: To evaluate the influence of immunomodulatory therapy (IMT) on visual and treatment outcomes of inflammatory choroidal neovascularization (iCNV) in patients affected by Multifocal Choroiditis (MFC), and to compare them to patients treated with steroids as needed. DESIGN: Multicenter retrospective matched cohort study. METHODS: Patients affected by MFC with iCNV were divided in a IMT group and a "steroids as needed" group and matched according to the time between diagnosis and beginning of systemic treatment...
January 13, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38202060/systematic-review-of-myopia-progression-after-cessation-of-optical-interventions-for-myopia-control
#10
REVIEW
Yu-Chieh Chiu, Ping-Chiao Tsai, Ssu-Hsien Lee, Jen-Hung Wang, Cheng-Jen Chiu
Despite high discontinuation rates for myopia optical interventions, limited attention has been given to the potential rebound effects post-discontinuation. This systematic review aims to assess the extent of the rebound effects following the cessation of common clinical optical myopia-control interventions in children. A comprehensive search of PubMed, Embase, Cochrane CENTRAL, and ClinicalTrials.gov was conducted from inception to October 2023. The rebound effects, defined as changes in the axial length or spherical equivalent during and after treatment cessation, were categorized into four levels...
December 21, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38195467/unilateral-acute-posterior-multifocal-placoid-pigment-epitheliopathy-apmppe-with-delayed-contralateral-eye-involvement
#11
JOURNAL ARTICLE
Emanuel Mordechaev, Gabriel Shakarov, Deep Parikh
BACKGROUND: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare presumed inflammatory chorioretinopathy characterized by creamy, yellow-white placoid lesions at the level of the retinal pigment epithelium (RPE). Unilateral cases often have fellow eye involvement within days to a few weeks. This report details a rare case of delayed contralateral APMPPE, in which unilateral lesion resolution was followed by contralateral eye involvement 31 months later. CASE PRESENTATION: A 38-year-old woman presented with three days of blurry vision and photopsias in the right eye (OD)...
January 9, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38181975/punctate-inner-choroidopathy-a-review-of-the-current-diagnostic-and-therapeutic-approaches
#12
REVIEW
Dimitrios Kalogeropoulos, Najiha Rahman, Farid Afshar, Nigel Hall, Andrew John Lotery
Punctate inner choroidopathy (PIC) is an uncommon idiopathic inflammatory condition characterized by multifocal chorioretinopathy that primarily affects young adults, with a predilection for myopic females. Clinically, it manifests as small, yellowish-white lesions in the inner choroid and outer retina, often associated with inflammatory changes. Accurate diagnosis remains a challenge due to its resemblance to other posterior uveitic entities, necessitating an astute clinical eye and advanced imaging techniques for differentiation...
March 2024: Progress in Retinal and Eye Research
https://read.qxmd.com/read/38166867/the-multimodal-imaging-features-and-outcomes-of-multifocal-choroiditis-punctate-inner-choroidopathy-lesion-with-multiple-evanescent-white-dot-syndrome-like-features-a-retrospective-study
#13
JOURNAL ARTICLE
Chunli Chen, Yizhe Cheng, Zhihan Zhang, Yang Zhang, Simeng Hou, Ge Wang, Xiaoyan Peng
BACKGROUND: Multiple evanescent white dot syndrome (MEWDS)-like features is a rare condition triggered by a macular disease or iatrogenic injury, exhibiting MEWDS changes in the fundus. This study aims to describe the multimodal imaging features and outcomes of multifocal choroiditis/punctate inner choroidopathy (MFC/PIC) lesions with MEWDS-like features. METHODS: Six cases were studied retrospectively. All cases were given regional and oral corticosteroids. RESULTS: All cases showed an isolated juxtafoveal yellowish-white MFC/PIC lesion with disruption of RPE-Bruch's membrane-choriocapillaris complex (RPE-BM-CC), subretinal hyperreflective materials and choroidal thickening on optical coherence tomography...
January 2, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38138261/management-of-bilateral-diffuse-uveal-melanocytic-proliferation-bdump-a-case-report
#14
Nataša Drača, Emma Grace Orešković, Ratimir Lazić, Marija Vukojević, Andrea Radolović Bertetić, Nenad Vukojević
Background and Objectives : This study reports a case of a 62-year-old patient experiencing a significant decline in vision over the past three months. The initial best-corrected visual acuity (BCVA) of 20/20 in both eyes diminished to 20/200 in the right eye (RE) and counting fingers (CF) in the left eye (LE) within this timeframe. The patient was diagnosed with stage 4 ovarian cancer just one month before the significant vision deterioration. Materials and Methods : A thorough ophthalmologic examination revealed a notable progression of cataracts and the presence of subretinal fluid on the posterior pole, accompanied by choroidal thickening...
December 13, 2023: Medicina
https://read.qxmd.com/read/38132220/recent-advances-in-imaging-macular-atrophy-for-late-stage-age-related-macular-degeneration
#15
REVIEW
Anny M S Cheng, Kakarla V Chalam, Vikram S Brar, David T Y Yang, Jineel Bhatt, Raphael G Banoub, Shailesh K Gupta
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. In late-stage AMD, geographic atrophy (GA) of dry AMD or choroidal neovascularization (CNV) of neovascular AMD eventually results in macular atrophy (MA), leading to significant visual loss. Despite the development of innovative therapies, there are currently no established effective treatments for MA. As a result, early detection of MA is critical in identifying later central macular involvement throughout time. Accurate and early diagnosis is achieved through a combination of clinical examination and imaging techniques...
December 10, 2023: Diagnostics
https://read.qxmd.com/read/38132210/presumed-onchocerciasis-chorioretinitis-spilling-over-into-north-america-europe-and-middle-east
#16
JOURNAL ARTICLE
Ahmad Mansour, Linnet Rodriguez, Hana Mansour, Madeleine Yehia, Maurizio Battaglia Parodi
BACKGROUND: Newer generation ophthalmologists practicing in the developed world are not very familiar with some tropical ocular diseases due to the absence of reports in the ophthalmic literature over the past thirty years. Because of world globalization or due to influx of immigrants from sub-Saharan Africa, exotic retinal diseases are being encountered more often in ophthalmology clinics. METHODS: A multicenter case series of chorioretinitis or optic neuritis with obscure etiology that used serial multimodal imaging...
December 8, 2023: Diagnostics
https://read.qxmd.com/read/38109671/distinctive-optical-coherence-tomography-angiography-and-indocyanine-green-angiography-imaging-patterns-in-topiramate-induced-choroidal-effusion
#17
JOURNAL ARTICLE
Jacques Bijon, Erin Flynn, K Bailey Freund
PURPOSE: To describe novel findings seen on optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) in a young male patient presenting with bilateral topiramate-induced choroidal effusion. METHODS: Retrospective case report. A comprehensive ophthalmic examination was conducted and multimodal imaging techniques, including B-scan ultrasound, OCT, OCTA, and ICGA were analyzed. RESULTS: A male in his 30s presented with a myopic shift due to bilateral choroidal effusion induced by a medication containing topiramate prescribed for weight loss...
December 12, 2023: Retinal Cases & Brief Reports
https://read.qxmd.com/read/38060000/differential-diagnosis-of-myopic-choroidal-neovascularization-mcnv-insights-from-multimodal-imaging-and-treatment-implications
#18
REVIEW
Alessandro Feo, Luca De Simone, Luca Cimino, Martina Angi, Mario R Romano
PURPOSE: The aim of this article is to conduct a comprehensive systematic review about the current understandings and differential diagnosis of myopic choroidal neovascularization (mCNV) and other several similar diseases, describing their multimodal imaging analysis, prognostic implications, and current types of management. METHODS: This systematic review was performed based on a search on the PubMed database of relevant papers regarding mCNV and other entities discussed in the paper, according to our current knowledge...
December 7, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38022132/atypical-ocular-toxoplasmosis-multifocal-segmental-retinal-arteritis-kyrieleis-arteritis-and-peripheral-choroidal-leision
#19
Joobin Khadamy
A 45-year-old immunocompetent man with a two-week history of unilateral painful red eye was referred to the university hospital for further investigation. High intraocular pressure, corneal edema, large pigmented keratic precipitates, cells and flares in the anterior chamber, patches of iris transillumination with atrophy, multifocal segmental retinal arteritis (SRA) or Kyrieleis arteritis, and peripheral choroidal elevation with overlying vitritis without adjacent old scars were observed. Toxoplasmosis, varicella-zoster virus, herpes simplex, and cytomegalovirus serologies (IgG) were positive...
October 2023: Curēus
https://read.qxmd.com/read/38014882/surgical-treatment-of-bullous-exudative-retinal-detachment-secondary-to-atypical-bilateral-central-serous-chorioretinopathy
#20
JOURNAL ARTICLE
Hüseyin Baran Özdemir, Murat Yüksel, Murat Hasanreisoğlu, Gökhan Gürelik, Ahmet Murat Sarıcı, İlknur Tuğal-Tutkun, Şengül Özdek
This study aimed to report the diagnostic process, treatment, and follow-up of a patient with bullous exudative retinal detachment (RD) associated with an atypical variant of bilateral central serous chorioretinopathy (CSCR). A 28-year-old woman was referred to our clinic for total bullous RD in the right eye with a vision level of light perception only. She had been previously diagnosed with idiopathic uveal effusion syndrome and treated with systemic corticosteroid therapy with no response, and was referred to us for scleral window surgery...
November 28, 2023: Turkish Journal of Ophthalmology
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