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Multifocal choroiditis

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https://www.readbyqxmd.com/read/27904945/-sarcoidosis-and-uveitis-an-update
#1
REVIEW
J G Garweg
Ocular involvement in sarcoidosis is present in up to one third of patients and is frequently manifested before the underlying systemic disease has been diagnosed. With a view to the therapeutic consequences an early diagnosis of the underlying disease is advantageous. In cases of visual loss early diagnostic measures include invasive procedures, such as ultrasound-guided bronchoalveolar lavage and transbronchial biopsy, if nodular conjunctival or cutaneous manifestations which would confirm the diagnosis are not present...
November 30, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27898981/macular-features-in-retinitis-pigmentosa-correlations-among-ganglion-cell-complex-thickness-capillary-density-and-macular-function
#2
Lisa Toto, Enrico Borrelli, Rodolfo Mastropasqua, Alfonso Senatore, Luca Di Antonio, Marta Di Nicola, Paolo Carpineto, Leonardo Mastropasqua
Purpose: To investigate correlations among macular ganglion cell complex (GCC) layer thickness, macular capillary density, and macular function in patients affected by retinitis pigmentosa (RP). Methods: Fourteen patients (28 eyes) with previous diagnosis of RP were enrolled. The diagnosis of these conditions was made based on both clinical features and electrophysiological examination. All patients underwent a complete ophthalmologic examination, including optical coherence tomography angiography (OCTA) and multifocal electroretinogram (mfERG)...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27896896/presumed-tuberculous-uveitis-in-non-endemic-country-for-tuberculosis-case-series-from-a-new-zealand-tertiary-uveitis-clinic
#3
Ken K Ng, Mitzi Nisbet, Erika M Damato, Joanne L Sims
BACKGROUND: To describe the clinical spectrum of presumed tuberculous (TB) uveitis in a developed, non-endemic country of high immigrant population. DESIGN: Retrospective review of a consecutive case series. PARTICIPANTS: All 39 patients diagnosed with presumed TB uveitis at the tertiary uveitis service in Auckland from 2007 to 2014. METHODS: Clinical chart review. MAIN OUTCOME MEASURES: Patient demographics, risk factors, ophthalmic manifestations, management and outcome...
November 28, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27880741/optical-coherence-tomography-angiography-of-chorioretinal-lesions-due-to-idiopathic-multifocal-choroiditis
#4
Sarwar Zahid, Kevin C Chen, Jesse J Jung, Chandrakumar Balaratnasingam, Quraish Ghadiali, John Sorenson, Soraya Rofagha, K Bailey Freund, Lawrence A Yannuzzi
PURPOSE: To evaluate the spectrum of macular chorioretinal lesions occurring in idiopathic multifocal choroiditis using optical coherence tomography angiography (OCTA) to evaluate those showing neovascular flow. METHODS: This was a descriptive, retrospective study of 18 eyes of 14 patients with multifocal choroiditis. Macular lesions were characterized as subretinal pigment epithelium, subretinal, or mixed and evaluated during active and presumed inactive states of multifocal choroiditis...
October 31, 2016: Retina
https://www.readbyqxmd.com/read/27871762/clinical-and-histopathologic-ocular-findings-in-disseminated-mycobacterium-chimaera-infection-after-cardiothoracic-surgery
#5
Sandrine A Zweifel, Daniela Mihic-Probst, Christine A Curcio, Daniel Barthelmes, Andrea Thielken, Peter M Keller, Barbara Hasse, Christian Böni
PURPOSE: To investigate and characterize clinical and histopathologic ocular findings in patients with disseminated infection with Mycobacterium chimaera, a slow-growing nontuberculous mycobacterium (NTM), subsequent to cardiothoracic surgery. DESIGN: Observational case series. PARTICIPANTS: Five white patients (10 eyes). METHODS: Analysis of clinical ocular findings, including visual acuity, slit-lamp biomicroscopy, spectral-domain optical coherence tomography (SD OCT), fundus autofluorescence (FAF), and fluorescein angiography/indocyanine green (ICG) angiography findings, of patients with a disseminated M...
November 18, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27843513/bilateral-choroidal-metastases-from-endobronchial-carcinoid-treated-with-somatostatin-analogues
#6
Deborah De Bruyn, Jan Lamont, Erik Vanderstraeten, Simon Van Belle, Elise Platteau, Julie De Zaeytijd, Kristien P Hoornaert
OBJECTIVE: To describe a patient with bilateral multifocal choroidal metastases from an endobronchial carcinoid treated with a somatostatin analogue. METHOD: A 60-year-old woman presenting with photopsia in the left eye underwent an extensive ophthalmic examination, including fluorescein angiography, OCT and ultrasound. RESULTS: Fundoscopy revealed a small retinal tear in the left eye, for which she received laser treatment. In addition, choroidal masses were detected in both eyes...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27843240/choroidal-melanoma-masquerading-as-multifocal-central-serous-chorioretinopathy
#7
Pukhraj Rishi, Ramya Appanraj, Tarun Sharma
A 56 year-old-male presented with diminution of vision in right eye of 2 months duration. His best corrected visual acuity (BCVA) was 20/25. Anterior segment examination was bilaterally normal. Right fundus revealed oval, raised, pigmented lesion in superotemporal quadrant with subfoveal fluid. Fundus fluroscein angiography (FFA) showed multiple pinpoint leakages. Acoustic hollowing on ultrasound (USG) was typical of choroidal melanoma. A high index of suspicion is required for the diagnosis of small choroidal melanoma that could present with multiple focal leaks and subretinal fluid simulating multifocal central serous retinopathy (CSR)...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27824724/multiple-evanescent-white-dot-syndrome-with-central-visual-loss
#8
Gaetano R Barile, Sarah A Harmon
PURPOSE: To report the clinical case of a 64-year-old man who developed several features of multiple evanescent white dot syndrome (MEWDS) but with central visual loss that persisted because of significant structural macular disease. METHODS: A case report was generated by a review of the clinical course and imaging investigations of one patient, along with review of the literature. RESULTS: A 64-year-old man noted decreased vision in the right eye for 2 weeks, associated with a central scotoma with shimmering, gauze effect of the vision...
November 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27820754/en-face-optical-coherence-tomography-of-multiple-evanescent-white-dot-syndrome
#9
Daniel Su, David Xu, Nopasak Phasukkijwatana, David Sarraf
PURPOSE: To report novel en face imaging findings of multiple evanescent white dot syndrome. METHODS: A 25-year-old woman presented with photopsia and vision loss affecting the left eye. Ophthalmic examination, color fundus photography, fluorescein angiography, spectral domain optical coherence tomography (SD-OCT), fundus autofluorescence, en face OCT, and OCT angiography were performed. RESULTS: The diagnosis of multiple evanescent white dot syndrome was made based on clinical examination and multimodal imaging findings...
November 3, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27779556/multimodal-imaging-of-serpiginous-choroiditis
#10
Hashim Ali Khan, Muhammad Aamir Shahzad
PURPOSE: To report a case of atypical serpiginous choroiditis with previously unreported findings on optical coherence tomographic angiography. CASE REPORT: A 35-year-old otherwise healthy man had a 1-week history of vision loss in his right eye. The visual acuity in right eye was counting fingers at 1 meter. Fundoscopy showed a classic peripapillary serpiginous lesion and a solitary macular lesion. Fundus fluorescein angiography revealed early hypofluorescence of active lesions with gradual increase in fluorescence across the phase of angiogram...
October 25, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27776541/course-of-disease-in-multifocal-choroiditis-lacking-sufficient-immunosuppression-a-case-report
#11
Katharina Schroeder, Tobias Meyer-Ter-Vehn, Heidi Fassnacht-Riederle, Rainer Guthoff
BACKGROUND: Multifocal choroiditis with panuveitis is a rare disease. The educational merit of this case presentation results from the good documentation and the impressive ocular fundus pictures. CASE PRESENTATION: We illustrate the 3-year course of disease in a 22-year-old myopic white woman with multifocal choroiditis with panuveitis and secondary choroidal neovascularization. The activity of the disease was evaluated clinically by optical coherence tomography and fluorescein angiography...
October 24, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27759710/optical-coherence-tomography-angiography-shows-inner-choroidal-ischemia-in-acute-posterior-multifocal-placoid-pigment-epitheliopathy
#12
Rosa Dolz-Marco, David Sarraf, Vincent Giovinazzo, K Bailey Freund
PURPOSE: To describe multimodal imaging findings of an evolving case of acute posterior multifocal placoid pigment epitheliopathy occurring in a young healthy male. METHODS: Case report of a patient with acute posterior multifocal placoid pigment epitheliopathy including comprehensive systemic and ocular examinations. Ultra-widefield autofluorescence, fluorescein angiography, indocyanine green angiography, and serial optical coherence tomography angiography were performed...
October 18, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27751823/punctate-inner-choroidopathy-a-review
#13
Dana Ahnood, Savitha Madhusudhan, Marie D Tsaloumas, Nadia K Waheed, Pearse A Keane, Alastair K Denniston
Punctate Inner Choroidopathy (PIC), an idiopathic inflammatory multifocal chorioretinopathy that predominantly affects young myopic women, appears to be relatively rare, but there is limited data to support accurate estimates of prevalence, and it is likely that the condition is under-diagnosed. The etiological relationship between PIC and other conditions within the 'white dot syndromes' group remains uncertain. We, like others, would suggest that PIC and multifocal choroiditis with panuveitis (MCP) represent a single disease process that is modified by host factors (including host immunoregulation) to cause the range of clinical phenotypes seen...
October 14, 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/27749792/multifocal-choroidal-melanoma-in-a-patient-with-germ-line-brca-associated-protein-1-mutation
#14
Raksha Rao, Renelle Pointdujour-Lim, Arupa Ganguly, Carol L Shields
PURPOSE: To report a case of unilateral multifocal melanoma in a patient with germ line BRCA-associated protein 1 mutation. METHODS: Case report. RESULTS: A 67-year-old white woman with a family history of lung and liver cancers developed blurred visual acuity of 20/30 in the left eye. She was discovered to have two independent pigmented choroidal melanomas in the macula and superotemporally, both demonstrating overlying subretinal fluid and orange pigment...
October 4, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27662233/why-the-dots-are-black-only-in-the-late-phase-of-the-indocyanine-green-angiography-in-multiple-evanescent-white-dot-syndrome
#15
Alain Gaudric, Sarah Mrejen
PURPOSE: To determine what retinal layer is primarily involved in multiple evanescent white dot syndrome compared with acute posterior multifocal placoid pigment epitheliopathy using multimodal imaging including indocyanine green angiography. METHODS: Color fundus photographs and fluorescein angiography, ICGA and spectral domain optical coherence tomography images of two typical acute cases, one of acute posterior multifocal placoid pigment epitheliopathy and one of multiple evanescent white dot syndrome, were assessed and compared...
September 21, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27598542/optical-coherence-tomography-angiography-features-of-paradoxical-worsening-in-tubercular-multifocal-serpiginoid-choroiditis
#16
Aniruddha Agarwal, Kanika Aggarwal, Ankit Deokar, Spoorti Krishna Reddy Mandadi, Simar Rajan Singh, Ramandeep Singh, Aman Sharma, Reema Bansal, Vishali Gupta
PURPOSE: To describe optical coherence tomography angiography (OCTA) features of lesions of tubercular multifocal serpiginoid choroiditis (TB MSC) that developed paradoxical worsening (PW). METHODS: In this prospective study, subjects with TB MSC who developed PW upon initiation of anti-tubercular therapy were included. Multimodal imaging was performed using OCTA, enhanced-depth imaging OCT, fluorescein angiography (FA), and indocyanine green angiography (ICGA)...
September 6, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27590527/deep-inside-multifocal-choroiditis-an-optical-coherence-tomography-angiography-approach
#17
Alessio Cerquaglia, Marco Lupidi, Tito Fiore, Barbara Iaccheri, Paolo Perri, Carlo Cagini
The aim of the study was to report the clinical utility of optical coherence tomography angiography (OCT-A) in characterizing and differentiating inflammatory lesions and choroidal neovascularization (CNV) in multifocal choroiditis (MFC). A patient affected by MFC complaining central visual loss and scotoma in his left eye was fully investigated with dye-based angiographies, structural OCT and OCT-A. A reactivation of macular CNV was initially suspected, while OCT-A revealed the absence of any decorrelation signal both over the retinal pigment epithelium (RPE) and between RPE and Bruchs' membrane...
September 2, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27576870/dexamethasone-intravitreal-implants-in-the-management-of-tubercular-multifocal-serpiginoid-choroiditis
#18
Alex Fonollosa, Sonia Valsero, Joseba Artaraz, Ioana Ruiz-Arruza
BACKGROUND: Continuous progression of lesions despite an adequate treatment has been described in tubercular multifocal serpiginoid choroiditis. Reported treatments for this paradoxical response include systemic steroids, immunosuppressive drugs, and intravitreal methotrexate. We describe the use of dexamethasone intravitreal implants in a patient presenting with this condition. FINDINGS: A 46-year-old woman sought medical attention for scotomas in her left eye...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27555066/punctate-inner-choroidopathy-complicated-with-exudative-neurosensory-detachment-a-favourable-response-to-treatment-with-systemic-corticosteroids-and-intravitreal-ranibizumab
#19
M Roca, M Menezo, J M Ronchera, J M Esteban, B Roca
CASE REPORT: Punctate inner choroidopathy (PIC) is a variant of multifocal choroiditis that principally affects young and healthy women. A case of this condition is described in a woman who presented with a scotoma as the main complaint. Four months after the diagnosis of PIC, she developed an exudative neurosensory detachment associated with an active focus of juxtafoveal choroiditis. Finally, with systemic corticosteroids and intravitreal ranibizumab, she made excellent progress. DISCUSSION: Intravitreal ranibizumab, associated with systemic corticosteroids, may be an effective treatment for exudative neurosensory detachment complicating PIC...
August 20, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27539089/choroidal-neovascularisation-on-optical-coherence-tomography-angiography-in-punctate-inner-choroidopathy-and-multifocal-choroiditis
#20
Ashleigh L Levison, Kimberly M Baynes, Careen Y Lowder, Peter K Kaiser, Sunil K Srivastava
PURPOSE: To describe the findings seen on optical coherence tomography angiography (OCTA) in patients with punctate inner choroidopathy (PIC) and multifocal choroiditis and panuveitis (MCP) complicated by choroidal neovascular membranes. METHODS: This was an Institutional Review Board-approved prospective, descriptive case series. 12 patients with PIC and MCP complicated by choroidal neovascularisation (CNV) were included. Each patient underwent slit-lamp examination by a uveitis specialist followed by conventional spectral domain OCT imaging of the macula...
August 18, 2016: British Journal of Ophthalmology
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