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Multifocal choroiditis

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https://www.readbyqxmd.com/read/29230338/optical-coherence-tomography-angiography-of-punctate-inner-choroidopathy
#1
Blake M Hampton, Christopher M Aderman, Harry W Flynn, Jayanth Sridhar
Purpose: To report a case of bilateral choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) visualized utilizing optical coherence tomography angiography (OCT-A). Methods: Case report. Results: A 29-year-old woman presented with new visual symptoms in both eyes. Fundoscopic exam revealed bilateral multifocal, small, well-defined lesions consistent with PIC. Optical coherence tomography demonstrated subretinal fluid and retinal pigment epithelium detachments (RPEDs) in both eyes...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29190170/the-role-of-dexamethasone-implant-in-the-management-of-tubercular-uveitis
#2
Aniruddha Agarwal, Sabia Handa, Kanika Aggarwal, Mansi Sharma, Ramandeep Singh, Aman Sharma, Rupesh Agrawal, Kusum Sharma, Vishali Gupta
PURPOSE: To study the safety and efficacy of intravitreal injection of dexamethasone implant in the management of posterior segment involvement in tubercular uveitis (TBU). METHODS: In this study, retrospective analysis of safety and efficacy of intravitreal injection of dexamethasone implant for various indications such as cystoid macular edema (CME), vitritis, or paradoxical worsening in TB-related intermediate uveitis, retinal vasculitis, and multifocal serpiginoid choroiditis (MSC) was performed...
November 30, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29176533/idiopathic-multifocal-choroiditis-presenting-with-a-transient-peripapillary-white-ring
#3
Sarra Gattoussi, Quraish Ghadiali, Rosa Dolz-Marco, K Bailey Freund
PURPOSE: We describe with multimodal imaging the presentation and follow-up for a patient with idiopathic multifocal choroiditis and a transient peripapillary white ring. METHODS: Case report. RESULTS: A 39-year-old Asian woman was initially seen for an evaluation of lattice degeneration in 2015. Her medical history included Graves disease and psoriasis. Best-corrected visual acuity was 20/25 in her right eye and 20/25 in her left eye. Ultra-widefield fundus autofluorescence imaging showed a curvilinear hyperautofluorescent line in her right eye...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29152599/a-novel-clinical-sign-in-intraocular-tuberculosis-active-chorioretinitis-within-chorioretinal-atrophy
#4
Avinash Pathengay, Bhavik Panchal, Himadri Choudhury, Soumyava Basu, Nidhi Relhan, Harry W Flynn
Purpose: To report a novel clinical sign in patients with intraocular tuberculosis. The current study is an observational consecutive case series of patients diagnosed with intraocular tuberculosis managed at a tertiary eye care centre from June 1, 2012 to December 31, 2015. Observations: The diagnosis of intraocular tuberculosis was made in 6 patients based on ocular features suggestive of tuberculosis along with a positive tuberculin skin testing and chest X-ray consistent with tuberculosis...
September 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29117661/a-rare-case-of-infectious-multifocal-serpiginoid-choroiditis
#5
Miloš Mitrašević, Svetlana Jovanović, Filip Radotić, Snežana Pešić, Zorica Jovanović
Multifocal serpiginoid choroiditis is an infectious variety of serpiginous choroiditis. The disease is characterized by infectious etiology and overlapping clinical features in an intermediary form of acute posterior multifocal placoid pigment epitheliopathy and serpiginous choroiditis. In a 33-year-old patient, bilateral multiple placoid partially confluent chorioretinal lesions were diagnosed after a febrile flu-like episode. On the right eye, there was a progressive decrease in visual acuity. Later, the lesions had a prolonged progressive devastating clinical course and widespread distribution of placoid lesions, and took the form of serpiginoid choroiditis...
December 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29109901/posterior-polar-central-choroidal-dystrophy-a-case-report
#6
Funda Dikkaya, Mustafa Özsütçü, Merve Özbek, Sevil Karaman Erdur, Fevzi Şentürk
A 52-year-old male presented with a 25-year history of decreasing vision. Best corrected visual acuity was 0.3 in his right and 0.2 in his left eye. Fundoscopic examination showed bilateral symmetric atrophy of the retinal pigment epithelium and choriocapillaris in the posterior polar areas between vascular arcades and surrounding the optic disc. On fluorescein angiography, the large choroidal vessels beneath these affected regions were easily seen. Fundus autofluorescence imaging showed clearly defined hypoautofluorescent areas that corresponded to the aforementioned lesions...
October 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29099668/successful-conservative-treatment-of-massive-choroidal-relapse-in-2-retinoblastoma-patients-monitored-by-ultrasound-biomicroscopy-and-or-spectral-domain-optic-coherence-tomography
#7
Christina Stathopoulos, Marie-Claire Gaillard, Francesco Puccinelli, Philippe Maeder, Doris Hadjistilianou, Maja Beck-Popovic, Francis L Munier
PURPOSE: To report the occurrence and management of secondary choroidal infiltration in two retinoblastoma (rb) patients. METHODS: Fundus examination and imaging with spectral domain optical coherence tomography (SD-OCT), B-scan ultrasonography (B-scan), and ultrasound biomicroscopy (UBM). RESULTS: Case 1: A 19-month-old girl with multifocal unilateral group B rb pretreated with intravenous chemotherapy (IVC) was referred for further management...
November 3, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29049720/optical-coherence-tomography-angiography-in-the-evaluation-of-geographic-atrophy-area-extension
#8
Eleonora Corbelli, Riccardo Sacconi, Alessandro Rabiolo, Stefano Mercuri, Adriano Carnevali, Lea Querques, Francesco Bandello, Giuseppe Querques
Purpose: To investigate the application of optical coherence tomography angiography (OCT-A) in evaluation of geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Methods: Patients with GA were prospectively enrolled and studied with blue fundus autofluorescence (FAF), en face structural OCT, and OCT-A. OCT-A images were acquired using a slab of whole choroid, whereas en face structural OCT images were obtained at the ellipsoid zone (EZ), at the choroidal (CH) level, and at the scleral (SC) level...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29020533/choroidal-structural-changes-in-tubercular-multifocal-serpiginoid-choroiditis
#9
Aniruddha Agarwal, Rupesh Agrawal, Neha Khandelwal, Alessandro Invernizzi, Kanika Aggarwal, Aman Sharma, Ramandeep Singh, Reema Bansal, Kusum Sharma, Nirbhai Singh, Vishali Gupta
PURPOSE: To assess choroidal vascular changes among patients with tubercular multifocal serpiginoid choroiditis (TB MSC) using previously validated techniques. METHODS: Patients with TB MSC (n = 18) and healthy controls (n = 30) underwent enhanced-depth imaging optical coherence tomography (EDI-OCT) imaging. Using previously validated algorithm of image binarization, EDI-OCT scans were segmented to derive total choroidal area, luminal area, stromal area, and choroidal vascularity index (CVI)...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29020501/ultra-wide-field-imaging-in-paradoxical-worsening-of-tubercular-multifocal-serpiginoid-choroiditis-after-the-initiation-of-anti-tubercular-therapy
#10
Kanika Aggarwal, Aniruddha Agarwal, Ankit Deokar, Ramandeep Singh, Reema Bansal, Aman Sharma, Kusum Sharma, Mangat R Dogra, Vishali Gupta
PURPOSE: To evaluate role of ultra-wide field (UWF) versus conventional imaging in the follow-up and paradoxical worsening (PW) of tubercular (TB) multifocal serpiginoid choroiditis (MSC). METHODS: Prospective observational study of patients with TB MSC undergoing UWF imaging, autofluorescence and fluorescein angiography was performed. A circle simulating central 75° field representing conventional imaging was drawn on UWF images. The information yielded by the two modalities, progression of choroiditis lesions and PW was compared...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29020496/clinical-outcomes-of-adjunctive-sustained-release-intravitreal-dexamethasone-implants-in-tuberculosis-associated-multifocal-serpigenoid-choroiditis
#11
Lubhani Jain, Krushna Gopal Panda, Soumyava Basu
PURPOSE: To analyze the safety and efficacy of sustained-release intravitreal dexamethasone implant (Ozurdex) in management of TB-associated multifocal serpiginoid choroiditis (MSC). METHODS: Retrospective review of TB-associated MSC patients, treated with anti-TB therapy (ATT) and adjunctive intravitreal Ozurdex. RESULTS: Nine eyes of six patients were included. Four patients required Ozurdex implant for progressive or new lesions following ATT and two for additional systemic contraindications to corticosteroids - hyperglycemia and uncontrolled hypertension, respectively...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28983094/application-of-oct-angiography-to-characterise-the-evolution-of-chorioretinal-lesions-in-acute-posterior-multifocal-placoid-pigment-epitheliopathy
#12
T R Burke, C J Chu, S Salvatore, C Bailey, A D Dick, R W J Lee, A H Ross, E Carreño
PurposeThe aim of this study was to determine a sequence of structural changes in acute posterior multifocal placoid pigment epitheliopathy (APMPPE) using optical coherence tomography-angiography (OCT-A) and comparing with other imaging modalities.Patients and methodsPatients with a new diagnosis of acute-onset APMPPE referred to a regional specialist centre from October 2015 to October 2016 were included. Multimodal imaging employed on all patients from diagnosis included the following: fundus fluorescein angiography, indocyanine green angiography, fundus autofluorescence, spectral domain-OCT (SD-OCT), and OCT-A...
October 2017: Eye
https://www.readbyqxmd.com/read/28960121/multimodal-evaluation-of-patients-with-acute-posterior-multifocal-placoid-pigment-epitheliopathy-and-serpiginous-choroiditis
#13
Monique Mangeon, Claudio Zett, Camila Amaral, Eduardo Novais, Cristina Muccioli, Gabriel Andrade, Heloisa Nascimento, Rubens Belfort
PURPOSE: To evaluate retinal and choroidal changes in patients with non-granulomatous choroiditis using the multimodality imaging (MMI). METHODS: Eight eyes of four patients were analyzed. Three patients (six eyes) were diagnosed with serpiginous choroiditis (SC) and one patient (two eyes) with acute posterior multifocal placoid pigment epitheliopathy (APMPPE). The patients were imaged on the same day using the RTVue Avanti XR instrument OCT/OCTA (Optovue Inc, Fremont, CA), Heidelberg Retina Angiograph 2 FAF and FA (Heidelberg Engineering, Germany), and TRC50DXi Topcon FP (Topcon Medical Systems, Oakland, NJ)...
September 29, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28936058/multifocal-choroiditis-with-retinal-vasculitis-optic-neuropathy-and-keratoconus-in-a-young-saudi-male
#14
Yousef Dhafiri, Khalid Al Rubaie, Omar Kirat, William N May, Quan D Nguyen, Igor Kozak
The purpose of this study is to describe an association of unilateral multifocal choroiditis (MFC), retinal vasculitis, optic neuropathy, and bilateral keratoconus in a young Saudi male. A 27-year-old male patient with stable bilateral keratoconus presented with a painless vision loss in his left eye. Ophthalmic examinations revealed multiple foci of idiopathic chorioretinitis, retinal vasculitis, and mild optic disc leakage on fluorescein angiography, all of which resolved on systemic therapy with mycophenolate mofetil and prednisone after 3 months...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28902333/multi-modal-imaging-including-optical-coherence-tomography-angiography-in-patients-with-posterior-multifocal-placoid-pigment-epitheliopathy
#15
Jens Ulrich Werner, Christian Enders, Gerhard Klaus Lang, Gabriele Elisabeth Lang
BACKGROUND AND OBJECTIVE: New imaging methods provide novel insights into the pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Four patients (eight eyes) in acute, subacute, and late phases of the disease were analyzed with multi-modal imaging methods including optical coherence tomography angiography (OCTA), structural OCT, fundus photography, and fundus autofluorescence. One patient was observed during the entire disease course...
September 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28901810/the-incidence-of-ocular-tuberculosis-in-australia-over-the-past-10-years-2006-2015
#16
Erica Darian-Smith, Ming-Lee Lin, Lyndell L Lim, Peter McCluskey, Anthony J Hall
PURPOSE: To determine the incidence and clinical phenotype of ocular tuberculosis in Australia based on the mandatory jurisdictional health notification records for TB. METHODS: A whole population retrospective case series (Australia). Patients diagnosed with ocular tuberculosis were identified over the past 10 years (1 January 2006 to 31 December 2015) as recorded by individual Health Department jurisdictions per mandatory health notifications. The incidence rates were calculated based on the available Australian census data...
September 13, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28887115/blau-syndrome-associated-uveitis-preliminary-results-from-an-international-prospective-interventional-case-series
#17
Inge L Sarens, Ingele Casteels, Jordi Anton, Brigitte Bader-Meunier, Philippe Brissaud, Gaelle Chédeville, Rolando Cimaz, Andrew D Dick, Graciella Espada, Jorge Fernandez-Martin, Catherine M Guly, Eric Hachulla, Miroslav Harjacek, Raju Khubchandani, Friederike Mackensen, Rosa Merino, Consuelo Modesto, Antonio Naranjo, Sheila Oliveira-Knupp, Seza Özen, Christine Pajot, Athimalaipet V Ramanan, Ricardo Russo, Gordana Susic, Akaluck Thatayatikom, Caroline Thomée, Sebastiaan Vastert, John Bertin, Juan I Arostegui, Carlos D Rose, Carine H Wouters
PURPOSE: Provide baseline and preliminary follow-up results in a 5-year longitudinal study of Blau syndrome. DESIGN: Multicenter, prospective interventional case series. METHODS: Baseline data from 50 patients from 25 centers worldwide, and follow-up data for patients followed 1, 2, or 3 years at the end of study enrollment. Ophthalmic data were collected at baseline and yearly visits by means of a standardized collection form. RESULTS: Median age at onset of eye disease was 60 months and duration of eye disease at baseline 145 months...
September 6, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28871936/xanthoma-like-skin-changes-in-an-elderly-woman-with-a-normal-lipid-profile
#18
Piotr Nockowski, Zdzisław Woźniak, Adam Reich, Joanna Maj
Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis revealed the presence of mild monoclonal gammopathy with a presence of immunoglobulin G (IgG) kappa light chains; however, according to hematologist consultation, it did not require medical intervention. Imaging assessment and ultrasound examination did not show any specific involvement of internal organs...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28833469/clinicopathologic-features-and-magnetic-resonance-imaging-findings-in-24-cats-with-histopathologically-confirmed-neurologic-feline-infectious-peritonitis
#19
A H Crawford, A L Stoll, D Sanchez-Masian, A Shea, J Michaels, A R Fraser, E Beltran
BACKGROUND: Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Information regarding the magnetic resonance imaging (MRI) findings of neurologic FIP currently is limited, resulting in the need for better descriptions to optimize its use as a diagnostic tool. OBJECTIVE: To describe the clinicopathologic features and MRI findings in cases of confirmed neurologic FIP...
September 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28810039/distinguishing-white-dot-syndromes-with-patterns-of-choroidal-hypoperfusion-on-optical-coherence-tomography-angiography
#20
Jay C Wang, Inês Laíns, Lucia Sobrin, John B Miller
BACKGROUND AND OBJECTIVE: To compare patterns of choroidal hypoperfusion in white dot syndromes (WDS) using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Consecutive patients with WDS were imaged with either the Zeiss AngioPlex OCT Angiography (Carl Zeiss AG, Oberkochen, Germany) or the AngioVue OCT Angiography (Optovue, Fremont, CA) from February to November 2016. Four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), birdshot chorioretinopathy (BCR), presumed ocular histoplasmosis syndrome (POHS), and multiple evanescent white dot syndrome (MEWDS) were selected...
August 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
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