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inflammatory bowel disease and diet

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https://www.readbyqxmd.com/read/29036010/the-reasoning-beyond-the-potential-use-of-exclusive-enteral-nutrition-and-other-specified-diets-in-children-with-ulcerative-colitis
#1
Ron Shaoul, Stephanie Brown, Andrew S Day
The incidence of inflammatory bowel disease (IBD) is steadily on the rise in Western as well as in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. Furthermore, nutrition is involved in several aspects of pediatric inflammatory bowel disease (IBD), ranging from disease etiology to induction and maintenance of remission of disease. Exclusive enteral nutrition (EEN) has been shown to induce remission, including in patients with isolated colonic disease, and leads to mucosal healing in Crohn disease (CD)...
October 13, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29033765/celiac-disease-associated-with-a-benign-granulomatous-mass-demonstrating-self-regression-after-initiation-of-a-gluten-free-diet
#2
Abhinav Tiwari, Himani Sharma, Khola Qamar, Zubair Khan, Umar Darr, Anas Renno, Ali Nawras
Celiac disease is a chronic immune-mediated enteropathy in which dietary gluten induces an inflammatory reaction predominantly in the duodenum. Celiac disease is known to be associated with benign small bowel thickening and reactive lymphadenopathy that often regresses after the institution of a gluten-free diet. A 66-year-old male patient with celiac disease presented with abdominal pain and diarrheal illness. Computerized tomography of the abdomen revealed a duodenal mass. Endoscopic ultrasound-guided fine needle aspiration of the mass revealed bizarre stromal cells which represent a nonspecific tissue reaction to inflammation...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29030981/mesalazine-treatment-in-organotypic-culture-of-celiac-patients-comparative-study-with-gluten-free-diet
#3
EDITORIAL
Benedetti E, A Viscido, V Castelli, C Maggiani, M d'Angelo, E Di Giacomo, A Antonosante, A Picarelli, G Frieri
Given the central role of gluten in the pathogenesis of celiac disease (CD), a strict gluten-free diet (GFD) is the only validated treatment able to restore epithelium integrity and eliminate risks of complications. The risk of gluten contamination and the persistence of inflammation, even in patients strictly adhering to GFD, may render this treatment not always effective claiming the necessity of different new solutions. Oxidative and nitrosative stress have been indicated to play a pathophysiological role in CD...
October 14, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29027576/neonatal-ulcerative-colitis-associated-with-familial-mediterranean-fever-a-case-report
#4
Elif Sag, Ferhat Demir, Mustafa Emre Ercin, Mukaddes Kalyoncu, Murat Cakir
Neonatal inflammatory bowel disease (IBD) is a subclass of very early onset IBD that includes children younger than 1 month. It is characterized by more colonic involvement and monogenetic etiology, resistance to classical anti-inflammatory/immunomodulatory treatments and associated with colitis in first-degree family members. Herein we report a 3 month-old girl who was admitted with bloody diarrhea since 10 days of age. Her symptoms persist despite diet elimination. She was diagnosed with neonatal ulcerative colitis (UC) based on clinical, laboratory and histopathological examination...
October 13, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28989158/-environmental-risk-factors-for-induction-of-the-inflammatory-bowel-disease
#5
Yan Peng, Xinchun Liu, Xiaoyan Wang
Inflammatory bowel disease (IBD) is a group of intestinal chronic non-specific inflammatory disease with unknown etiology, including ulcerative colitis and Crohn's disease. The risk factors associated with pathogenesis of IBD include environmental factors, genetic factors, and immune factors.Among them, the environmental factors include smoking, drugs, diet, infection and psychological factors.
September 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28985721/a-descriptive-pilot-study-of-cytokine-production-following-stimulation-of-ex-vivo-whole-blood-with-commercial-therapeutic-feline-hydrolyzed-diets-in-individual-healthy-immunotolerant-cats
#6
Aarti Kathrani, Jennifer A Larsen, Gino Cortopassi, Sandipan Datta, Andrea J Fascetti
BACKGROUND: Hydrolyzed diets are used in companion animals for the diagnosis and treatment of adverse food reaction. Similarly, hydrolyzed formulas are used in human infants with severe inflammatory bowel disease or milk allergy, and these must meet the standard of hypoallergenicity through rigorous testing. Unfortunately, no standards are currently applied to hydrolyzed veterinary therapeutic diets, and data for the immunogenicity of feline diets is also not available. Therefore, the main aim of this pilot study was to determine if ex-vivo whole blood stimulation assays could be used to characterize the cytokine response to hydrolyzed commercial diets in a small number of individual healthy immunotolerant cats...
October 6, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28983289/dietary-heme-induces-gut-dysbiosis-aggravates-colitis-and-potentiates-the-development-of-adenomas-in-mice
#7
Marco Constante, Gabriela Fragoso, Annie Calvé, Macha Samba-Mondonga, Manuela M Santos
Dietary heme can be used by colonic bacteria equipped with heme-uptake systems as a growth factor and thereby impact on the microbial community structure. The impact of heme on the gut microbiota composition may be particularly pertinent in chronic inflammation such as in inflammatory bowel disease (IBD), where a strong association with gut dysbiosis has been consistently reported. In this study we investigated the influence of dietary heme on the gut microbiota and inferred metagenomic composition, and on chemically induced colitis and colitis-associated adenoma development in mice...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28976231/dietary-quercetin-ameliorates-experimental-colitis-in-mouse-by-remodeling-the-function-of-colonic-macrophages-via-a-heme-oxygenase-1-dependent-pathway
#8
Songwen Ju, Yan Ge, Ping Li, Xinxin Tian, Haiyan Wang, Xiaocui Zheng, Songguang Ju
Inflammatory bowel disease (IBD) results from a chronic intestinal inflammation and tissue destruction via an aberrant immune-driven inflammatory response towards an altered gut microbiota. Dietary intervention is becoming an attractive avenue for the therapy of colitis because diet is a key determinant of the mucosal immune response. Quercetin (QCN) is the most common in nature and the major representative of dietary antioxidant flavonoids, which has been demonstrated to influence the progression of colitis...
October 4, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28970717/helminths-as-an-alternative-therapy-for-intestinal-diseases
#9
EDITORIAL
Aytan Miranda Sipahi, Daniel Machado Baptista
Animal models and clinical studies have shown that helminth infections exert immunomodulatory activity, altering intestinal permeability and providing a potential beneficial action on autoimmune and inflammatory disorders in human beings, such as inflammatory bowel disease (IBD) and celiac disease. This is consistent with the theory that intestinal microbiota is responsible for shaping human immunological responses. With the arrival of the immunobiologic era and the use of antibodies, we propose a distinctive pathway for treating patients with IBD and celiac disease...
September 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28965192/repeated-oral-exposure-to-n-%C3%AE%C2%B5-carboxymethyllysine-a-maillard-reaction-product-alleviates-gut-microbiota-dysbiosis-in-colitic-mice
#10
Nesreen ALJahdali, Pascale Gadonna-Widehem, Carine Delayre-Orthez, David Marier, Benjamin Garnier, Franck Carbonero, Pauline M Anton
BACKGROUND: Diet is suggested to participate in the etiology of inflammatory bowel diseases (IBD). Repeated exposure to Maillard reaction products (MRPs), molecules resulting from reduction reactions between amino acids and sugars during food heating, has been reported to be either potentially detrimental or beneficial to health. AIMS: The aim of this study is to determine the effect of repeated oral ingestion of N (ε)-carboxymethyllysine (CML), an advanced MRP, on the onset of two models of experimental IBD and on the gut microbiota composition of mice...
September 30, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28961811/research-gaps-in-diet-and-nutrition-in-inflammatory-bowel-disease-a-topical-review-by-d-ecco-working-group-dietitians-of-ecco
#11
Rotem Sigall-Boneh, Arie Levine, Miranda Lomer, Nicolette Wierdsma, Philip Allan, Gionata Fiorino, Simona Gatti, Daisy Jonkers, Jaroslaw Kierkus, Konstantinos H Katsanos, Silvia Melgar, Elif Saritas Yuksel, Kevin Whelan, Eytan Wine, Konstantinos Gerasimidis
Although the current doctrine of IBD pathogenesis proposes an interaction between environmental factors with gut microbiota in genetically-susceptible individuals, dietary exposures have attracted recent interest and are, at least in part, likely to explain the rapid rise in disease incidence and prevalence. The D-ECCO working group along with other ECCO experts with expertise in nutrition, microbiology, physiology and medicine reviewed the evidence investigating the role of diet and nutritional therapy in the onset, perpetuation and management of IBD...
August 10, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28961226/innovative-disease-model-zebrafish-as-an-in-vivo-platform-for-intestinal-disorder-and-tumors
#12
REVIEW
Jeng-Wei Lu, Yi-Jung Ho, Shih-Ci Ciou, Zhiyuan Gong
Colorectal cancer (CRC) is one of the world's most common cancers and is the second leading cause of cancer deaths, causing more than 50,000 estimated deaths each year. Several risk factors are highly associated with CRC, including being overweight, eating a diet high in red meat and over-processed meat, having a history of inflammatory bowel disease, and smoking. Previous zebrafish studies have demonstrated that multiple oncogenes and tumor suppressor genes can be regulated through genetic or epigenetic alterations...
September 29, 2017: Biomedicines
https://www.readbyqxmd.com/read/28955125/dietary-phosphate-exacerbates-intestinal-inflammation-in-experimental-colitis
#13
Kohei Sugihara, Masashi Masuda, Mari Nakao, Maerjianghan Abuduli, Yukiko Imi, Naoko Oda, Toshiya Okahisa, Hironori Yamamoto, Eiji Takeda, Yutaka Taketani
The recent widespread consumption of Western diets and food additives worldwide is associated with excessive inorganic phosphate intake. However, researchers have known little about the impact of dietary phosphate intake on the development of inflammatory bowel disease to date. In this study, we investigated the effects of dietary phosphate on intestinal inflammation in experimental colitis. Sprague-Dawley rats were fed different phosphate diets (0.5%, 1.0% and 1.5% phosphate) with or without dextran sulfate sodium...
September 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/28949021/review-article-changes-in-the-epidemiology-of-inflammatory-bowel-disease-clues-for-aetiology
#14
REVIEW
C N Bernstein
BACKGROUND: The changing epidemiology of inflammatory bowel disease (IBD) in both the developed and developing worlds may provide insights into disease aetiology. Factors that impact on the gut microbiome are leading aetiological candidates. AIM: To review epidemiological studies and trends that identify risk factors for the development of IBD. METHODS: Studies that identified factors associated with the development of IBD differentially in children and adults were reviewed...
September 26, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28942174/gut-biofilm-forming-bacteria-in-inflammatory-bowel-disease
#15
REVIEW
Ankita Srivastava, Jaya Gupta, Sunil Kumar, Awanish Kumar
Inflammatory bowel disease (IBD) symbolizes a group of intestinal disorders in which prolonged inflammation occur in the digestive tract (esophagus, large intestine, small intestine mouth, stomach). Both genetic and environmental factors (infections, stress, diet) are involved in the development of IBD. As we know that bacteria are found in the intestinal mucosa of human and clinical observations revealed bacterial biofilms associated with patients of IBD. Various factors and microbes are found to play an essential role in biofilm formation and mucosal colonization during IBD...
September 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28937023/pre-illness-diet-as-risk-factor-in-pediatric-inflammatory-bowel-disease-in-saudi-arabia
#16
Mohammad I El Mouzan, Mohammad A Al Mofarreh, Ahmad A Al Sarkhy, Asaad M Assiri, Yassin M Hamed
BACKGROUND/AIM: Inflammatory bowel disease (IBD) is increasing in Saudi Arabia but there's little knowledge about its risk factors. Our aim is to investigate the dietary risk factors of this disease in Saudi children. PATIENTS AND METHODS: The children investigated for IBD were prospectively enrolled. Those with confirmed IBD were designated cases and the others were controls. The average food frequency intake at least 3 months before onset of illness was obtained by direct interview and recorded on a modified food frequency questionnaire...
September 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28922258/dietary-fiber-intake-in-children-in-remission-or-with-mild-inflammatory-bowel-disease
#17
Aleksandra Pituch-Zdanowska, Piotr Albrecht, Marcin Banasiuk, Aleksandra Banaszkiewicz
OBJECTIVES: The aim of the study was to estimate intake of total dietary fiber, and its soluble and insoluble fractions, by children with inflammatory bowel disease (IBD) in comparison to healthy controls. METHODS: This was a prospective controlled study on children with IBD. Food consumption data were collected by using the 3-day diet record. For intake of soluble and insoluble fibers author's questionnaire was used. RESULTS: The study included 50 children with IBD (80% in clinical remission) and 50 healthy controls...
September 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28918484/drug-herb-interactions-in-the-elderly-patient-with-ibd-a-growing-concern
#18
REVIEW
Haider Rahman, Marina Kim, Galen Leung, Jesse A Green, Seymour Katz
Inflammatory bowel disease (IBD), which includes conditions such as Crohn's disease and ulcerative colitis, is becoming more prevalent with the elderly being the fastest growing group. Parallel to this, there is an increasing interest in the use of complementary and alternative medicine (CAM). Nearly half of patients with IBD have used CAM at one time. The elderly patients, however, are burdened by comorbid conditions, polypharmacy, and altered functional status. With increasing use of complementary and alternative medicine in our elderly patients with IBD, it is vital for the provider to provide counsel on drug-herb potential interactions...
September 16, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28905102/digestive-system-in-psoriasis-an-update
#19
REVIEW
Daniel Pietrzak, Aldona Pietrzak, Dorota Krasowska, Andrzej Borzęcki, Kinga Franciszkiewicz-Pietrzak, Beata Polkowska-Pruszyńska, Maja Baranowska, Kristian Reich
Psoriasis is a chronic inflammatory immune-mediated disorder associated and often coexisting with many other immune-related clinical conditions including those affecting the gastrointestinal tract. Data obtained from the reviewed literature suggest an association between psoriasis and pathologies of the oral cavity, both psoriasis-specific lesions, as well as non-specific, such as geographic tongue or fissured tongue. These findings show the importance of thorough examination of oral mucosa in psoriatic patients...
September 13, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28904640/short-term-dietary-methionine-supplementation-affects-one-carbon-metabolism-and-dna-methylation-in-the-mouse-gut-and-leads-to-altered-microbiome-profiles-barrier-function-gene-expression-and-histomorphology
#20
Isabelle R Miousse, Rupak Pathak, Sarita Garg, Charles M Skinner, Stepan Melnyk, Oleksandra Pavliv, Howard Hendrickson, Reid D Landes, Annie Lumen, Alan J Tackett, Nicolaas E P Deutz, Martin Hauer-Jensen, Igor Koturbash
BACKGROUND: Methionine, a central molecule in one-carbon metabolism, is an essential amino acid required for normal growth and development. Despite its importance to biological systems, methionine is toxic when administered at supra-physiological levels. The aim of this study was to investigate the effects of short-term methionine dietary modulation on the proximal jejunum, the section of the gut specifically responsible for amino acid absorption, in a mouse model. Eight-week-old CBA/J male mice were fed methionine-adequate (MAD; 6...
2017: Genes & Nutrition
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