keyword
MENU ▼
Read by QxMD icon Read
search

inflammatory bowel disease and diet

keyword
https://www.readbyqxmd.com/read/29209321/consumption-of-diet-containing-free-amino-acids-exacerbates-colitis-in-mice
#1
Adna Luciana Souza, Sarah Leão Fiorini Aguiar, Mariana Camila Gonçalves Miranda, Luisa Lemos, Mauro Andrade Freitas Guimaraes, Daniela Silva Reis, Patrícia Aparecida Vieira Barros, Emerson Soares Veloso, Toniana Gonçalves Carvalho, Fabiola Mara Ribeiro, Enio Ferreira, Denise Carmona Cara, Ana Cristina Gomes-Santos, Ana Maria Caetano Faria
Dietary proteins can influence the maturation of the immune system, particularly the gut-associated lymphoid tissue, when consumed from weaning to adulthood. Moreover, replacement of dietary proteins by amino acids at weaning has been shown to impair the generation of regulatory T cells in the gut as well as immune activities such as protective response to infection, induction of oral and nasal tolerance as well as allergic responses. Polymeric and elemental diets are used in the clinical practice, but the specific role of intact proteins and free amino acids during the intestinal inflammation are not known...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29206211/the-imbalance-between-n-6-n-3-polyunsaturated-fatty-acids-and-inflammatory-bowel-disease-a-comprehensive-review-and-future-therapeutic-perspectives
#2
REVIEW
Eleonora Scaioli, Elisa Liverani, Andrea Belluzzi
Eating habits have changed dramatically over the years, leading to an imbalance in the ratio of n-6/n-3 polyunsaturated fatty acids (PUFAs) in favour of n-6 PUFAs, particularly in the Western diet. Meanwhile, the incidence of inflammatory bowel disease (IBD) is increasing worldwide. Recent epidemiological data indicate the potential beneficial effect of n-3 PUFAs in ulcerative colitis (UC) prevention, whereas consumption of a higher ratio of n-6 PUFAs versus n-3 PUFAs has been associated with an increased UC incidence...
December 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29200733/amelioration-of-intestinal-barrier-dysfunction-by-berberine-in-the-treatment-of-nonalcoholic-fatty-liver-disease-in-rats
#3
Donghao Li, Jimin Zheng, Yiting Hu, Hongtao Hou, Shurong Hao, Na Liu, Yuzhen Wang
Objective: To investigate the effect of berberine (BBR) on intestinal barrier function in nonalcoholic fat liver disease (NAFLD) in rats. Materials and Methods: Rats were divided into three groups: normal diet group (control group [CON group]), high-fat diet feeding group (HFD group), and HFD with BBR group. After 8 weeks of HFD feeding, rats in the BBR group were given BBR intragastrically at a dose of 150 mg/kg daily for 4 weeks. The same volume of normal saline was given to the CON and HFD groups...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29183720/contemporary-applications-of-fecal-microbiota-transplantation-to-treat-intestinal-diseases-in-humans
#4
REVIEW
Christopher Staley, Alexander Khoruts, Michael J Sadowsky
The intestinal microbiota comprise an important organ that plays a vital role in host digestion, development, energy maintenance, hemostasis, and immunity. Disruption of the gut microbial community due to diet, lifestyle, or antibiotic exposure increases susceptibility to chronic infection and disease. Fecal microbiota transplantation (FMT) involves the transfer of gut microbiota from a healthy donor to a patient in order to restore normal diversity and function of the microbial community. This method has become a well established alternative therapy for the treatment of recurrent Clostridium difficile infection...
November 25, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29174952/interactions-between-diet-and-the-intestinal-microbiota-alter-intestinal-permeability-and-colitis-severity-in-mice
#5
Sean R Llewellyn, Graham J Britton, Eduardo J Contijoch, Olivia H Vennaro, Arthur Mortha, Jean-Frederic Colombel, Ari Grinspan, Jose C Clemente, Miriam Merad, Jeremiah J Faith
BACKGROUND & AIMS: It is not clear how the complex interactions between diet and the intestinal microbiota affect development of mucosal inflammation or inflammatory bowel disease. We investigated interactions between dietary ingredients, nutrients, and the microbiota in specific pathogen-free (SPF) and germ-free (GF) mice given more than 40 unique diets; we quantified individual and synergistic effects of dietary macronutrients and the microbiota on intestinal health and development of colitis...
November 23, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29173519/diet-as-a-therapeutic-option-for-adult-inflammatory-bowel-disease
#6
REVIEW
Samir Kakodkar, Ece A Mutlu
There are many mechanisms to explain how food may drive and ameliorate inflammation. Although there are no consistent macronutrient associations inflammatory bowel disease (IBD) development, many exclusion diets have been described: IgG-4 guided exclusion diet; semivegetarian diet; low-fat, fiber-limited exclusion diet; Paleolithic diet; Maker's diet; vegan diet; Life without Bread diet; exclusive enteral nutrition (EEN), the Specific Carbohydrate Diet (SCD) and the low FODMAP diet. The literature on diet and IBD is reviewed with a particular focus on EEN, SCD, and low FODMAP diets...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29173518/dietary-therapies-in-pediatric-inflammatory-bowel-disease-an-evolving-inflammatory-bowel-disease-paradigm
#7
REVIEW
Erin R Lane, Dale Lee, David L Suskind
Nutrition has long been recognized as a critical component in the treatment of pediatric inflammatory bowel disease (IBD). Formerly, nutritional interventions have focused on targeting improved weight gain and linear growth, as well as correction of micronutrient deficiencies. Recently, there has been growing interest and study of dietary interventions for induction and maintenance of remission. In addition to exclusive enteral nutrition, successes have been achieved with specific exclusion diets. This article evaluates current literature regarding the role of diet and nutrition in pathogenesis of disease, as well as the role of diet as primary therapy for pediatric IBD...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29141575/the-protective-effects-of-extra-virgin-olive-oil-on-immune-mediated-inflammatory-responses
#8
Rosa Casas, Ramon Estruch, Emilio Sacanella
BACKGROUND AND OBJECTIVE: The increasing interest in the Mediterranean diet (MeDiet) hinges on the relevant role it plays in inflammatory diseases. Several clinical, epidemiological and experimental evidences suggest that consumption of the MeDiet reduces the incidence of certain pathologies related to oxidative stress, chronic inflammation and immune system diseases such as cancer, atherosclerosis and cardiovascular disease (CVD). DISCUSSION: These reductions can be partially attributed to extra virgin olive oil (EVOO) consumption which has been described as a key bioactive food because of its high nutritional quality and its particular composition of fatty acids, vitamins and polyphenols...
November 13, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29141574/anti-inflammatory-activity-of-extra-virgin-olive-oil-polyphenols-which-role-in-the-prevention-and-treatment-of-immune-mediated-inflammatory-diseases
#9
Carmela Santangelo, Rosaria Vari, Beatrice Scazzocchio, Patrizia De Sanctis, Claudio Giovannini, Massimo D'Archivio, Roberta Masella
Altered inflammatory response characterizes chronic immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, and psoriasis. Accumulating evidence indicates that regular consumption of extra virgin olive oil (EVOO), the main source of fat in the Mediterranean diet, is associated with a reduced risk of developing chronic degenerative disorders such cardiovascular diseases, type 2 diabetes and cancer. The beneficial effects on health of EVOO have been attributed, besides to the monounsaturated fats content, to the presence of phenolic compounds that have antioxidant, anti-inflammatory and immunomodulatory properties...
November 13, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29139477/a-dietary-flavone-confers-communicable-protection-against-colitis-through-nlrp6-signaling-independently-of-inflammasome-activation
#10
K Radulovic, S Normand, A Rehman, A Delanoye-Crespin, J Chatagnon, M Delacre, N Waldschmitt, L F Poulin, J Iovanna, B Ryffel, P Rosenstiel, M Chamaillard
Flavones represent a class of polyphenols that are found in many plant-derived food sources. Herein, we provide evidence that the anti-inflammatory and antiproliferative effect of the flavone apigenin relies on the regulation of the gut microbiota by the NOD-like receptor family pyrin domain containing 6 (Nlrp6). When challenged by dextran sulfate sodium (DSS) in drinking water, mice were protected against colitis upon cohousing with apigenin-treated animals. In contrast, the protective effect was lost in the absence of Nlrp6...
November 15, 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/29110065/fungi-in-gastrointestinal-tracts-of-human-and-mice-from-community-to-functions
#11
REVIEW
Jiayan Li, Daiwen Chen, Bing Yu, Jun He, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Gang Tian, Zhiqing Huang, Yuheng Luo
Fungi are often ignored in studies on gut microbes because of their low level of presence (making up only 0.1% of the total microorganisms) in the gastrointestinal tract (GIT) of monogastric animals. Recent studies using novel technologies such as next generation sequencing have expanded our understanding on the importance of intestinal fungi in humans and animals. Here, we provide a comprehensive review on the fungal community, the so-called mycobiome, and their functions from recent studies in humans and mice...
November 6, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/29107964/obesogenic-diet-induced-gut-barrier-dysfunction-and-pathobiont-expansion-aggravate-experimental-colitis
#12
June-Chul Lee, Hae-Youn Lee, Tae Kang Kim, Min-Soo Kim, Young Mi Park, Jinyoung Kim, Kihyoun Park, Mi-Na Kweon, Seok-Hyung Kim, Jin-Woo Bae, Kyu Yeon Hur, Myung-Shik Lee
Consumption of a typical Western diet is a risk factor for several disorders. Metabolic syndrome is the most common disease associated with intake of excess fat. However, the incidence of inflammatory bowel disease is also greater in subjects consuming a Western diet, although the mechanism of this phenomenon is not clearly understood. We examined the morphological and functional changes of the intestine, the first site contacting dietary fat, in mice fed a high-fat diet (HFD) inducing obesity. Paneth cell area and production of antimicrobial peptides by Paneth cells were decreased in HFD-fed mice...
2017: PloS One
https://www.readbyqxmd.com/read/29101655/epithelial-barrier-function-in-gut-bone-signaling
#13
Naiomy Deliz Rios-Arce, Fraser L Collins, Jonathan D Schepper, Michael D Steury, Sandi Raehtz, Heather Mallin, Danny T Schoenherr, Narayanan Parameswaran, Laura R McCabe
The intestinal epithelial barrier plays an essential role in maintaining host homeostasis. The barrier regulates nutrient absorption as well as prevents the invasion of pathogenic bacteria in the host. It is composed of epithelial cells, tight junctions, and a mucus layer. Several factors, such as cytokines, diet, and diseases, can affect this barrier. These factors have been shown to increase intestinal permeability, inflammation, and translocation of pathogenic bacteria. In addition, dysregulation of the epithelial barrier can result in inflammatory diseases such as inflammatory bowel disease...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29093615/less-common-etiologies-of-exocrine-pancreatic-insufficiency
#14
REVIEW
Vikesh K Singh, Mark E Haupt, David E Geller, Jerry A Hall, Pedro M Quintana Diez
Exocrine pancreatic insufficiency (EPI), an important cause of maldigestion and malabsorption, results from primary pancreatic diseases or secondarily impaired exocrine pancreatic function. Besides cystic fibrosis and chronic pancreatitis, the most common etiologies of EPI, other causes of EPI include unresectable pancreatic cancer, metabolic diseases (diabetes); impaired hormonal stimulation of exocrine pancreatic secretion by cholecystokinin (CCK); celiac or inflammatory bowel disease (IBD) due to loss of intestinal brush border proteins; and gastrointestinal surgery (asynchrony between motor and secretory functions, impaired enteropancreatic feedback, and inadequate mixing of pancreatic secretions with food)...
October 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29091813/dietary-red-raspberries-attenuate-dextran-sulfate-sodium-induced-acute-colitis
#15
Shima Bibi, Yifei Kang, Min Du, Mei-Jun Zhu
Persistent intestinal inflammation severely impairs intestinal integrity resulting in inflammatory bowel disease. Red raspberries (RB) are a rich source of bioactive compounds; their beneficial effect on the colitis protection was evaluated in the current study using a dextran sulfate sodium (DSS)-induced acute colitis mouse model. Six-week-old mice were fed a standard rodent research diet supplemented with RB (0 or 5% w/w, n=20 each group) for 6 weeks. At the 4th week of dietary treatment, approximately half of mice in each dietary group (n=12 each group) were subjected to 2...
September 14, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29072609/rome-criteria-and-a-diagnostic-approach-to-irritable-bowel-syndrome
#16
REVIEW
Brian E Lacy, Nihal K Patel
Functional gastrointestinal disorders (FGIDs) account for at least 40% of all referrals to gastroenterologists. Of the 33 recognized adult FGIDs, irritable bowel syndrome (IBS) is the most prevalent, with a worldwide prevalence estimated at 12%. IBS is an important health care concern as it greatly affects patients' quality of life and imposes a significant economic burden to the health care system. Cardinal symptoms of IBS include abdominal pain and altered bowel habits. The absence of abdominal pain makes the diagnosis of IBS untenable...
October 26, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29056933/linking-the-gut-microbial-ecosystem-with-the-environment-does-gut-health-depend-on-where-we-live
#17
Nishat Tasnim, Nijiati Abulizi, Jason Pither, Miranda M Hart, Deanna L Gibson
Global comparisons reveal a decrease in gut microbiota diversity attributed to Western diets, lifestyle practices such as caesarian section, antibiotic use and formula-feeding of infants, and sanitation of the living environment. While gut microbial diversity is decreasing, the prevalence of chronic inflammatory diseases such as inflammatory bowel disease, diabetes, obesity, allergies and asthma is on the rise in Westernized societies. Since the immune system development is influenced by microbial components, early microbial colonization may be a key factor in determining disease susceptibility patterns later in life...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29047231/alterations-in-gut-microbiota-and-immunity-by-dietary-fat
#18
REVIEW
Bo Gie Yang, Kyu Yeon Hur, Myung Shik Lee
Gut microbiota play critical physiological roles in energy extraction from the intestine and in the control of systemic immunity, as well as local intestinal immunity. Disturbance of gut microbiota leads to the development of several diseases, such as colitis, inflammatory bowel diseases, metabolic disorders, cancer, etc. From a metabolic point of view, the gut is a large metabolic organ and one of the first to come into contact with dietary fats. Interestingly, excessive dietary fat has been incriminated as a primary culprit of metabolic syndrome and obesity...
November 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29036010/the-reasoning-beyond-the-potential-use-of-exclusive-enteral-nutrition-and-other-specified-diets-in-children-with-ulcerative-colitis
#19
Ron Shaoul, Stephanie Brown, Andrew S Day
The incidence of inflammatory bowel disease (IBD) is steadily on the rise in Western as well as in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. Furthermore, nutrition is involved in several aspects of pediatric inflammatory bowel disease (IBD), ranging from disease etiology to induction and maintenance of remission of disease. Exclusive enteral nutrition (EEN) has been shown to induce remission, including in patients with isolated colonic disease, and leads to mucosal healing in Crohn disease (CD)...
October 13, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29033765/celiac-disease-associated-with-a-benign-granulomatous-mass-demonstrating-self-regression-after-initiation-of-a-gluten-free-diet
#20
Abhinav Tiwari, Himani Sharma, Khola Qamar, Zubair Khan, Umar Darr, Anas Renno, Ali Nawras
Celiac disease is a chronic immune-mediated enteropathy in which dietary gluten induces an inflammatory reaction predominantly in the duodenum. Celiac disease is known to be associated with benign small bowel thickening and reactive lymphadenopathy that often regresses after the institution of a gluten-free diet. A 66-year-old male patient with celiac disease presented with abdominal pain and diarrheal illness. Computerized tomography of the abdomen revealed a duodenal mass. Endoscopic ultrasound-guided fine needle aspiration of the mass revealed bizarre stromal cells which represent a nonspecific tissue reaction to inflammation...
May 2017: Case Reports in Gastroenterology
keyword
keyword
79816
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"