keyword
https://read.qxmd.com/read/38635940/uptake-of-risk-reducing-measures-cascade-testing-and-related-challenges-among-carriers-of-breast-cancer-associated-germline-pathogenic-variants-in-mexico
#1
JOURNAL ARTICLE
Fernanda Mesa-Chavez, Yanin Chavarri-Guerra, Dione Aguilar-Y-Mendez, Andrea Becerril-Gaitan, Bryan F Vaca-Cartagena, Araceli Carrillo-Bedoya, Salvador Santiesteban-González, Alejandro Aranda-Gutierrez, Andrés Rodríguez-Faure, Daniela Obregon-Leal, Gregorio Quintero-Beuló, Jose L Rodriguez-Olivares, Melina Miaja, Jeffrey N Weitzel, Cynthia Villarreal-Garza
PURPOSE: Genetic cancer risk assessment (GCRA) provides pathogenic variant (PV) carriers with the invaluable opportunity to undertake timely cancer risk-reducing (RR) measures and initiate cascade testing (CT). This study describes the uptake of these strategies and the related barriers among breast cancer-associated germline PV carriers in Mexico. METHODS: Carriers who were at least 6 months after disclosure of genetic test results at two GCRA referral centers were invited to answer a survey assessing sociodemographic characteristics, awareness of their carrier status and its implications, uptake of RR measures according to international guidelines by PV, CT initiation, and associated challenges...
April 2024: JCO global oncology
https://read.qxmd.com/read/38635695/health-care-utilisation-of-asylum-seekers-and-refugees-in-the-south-west-of-germany
#2
JOURNAL ARTICLE
Annabelle J Bockey, Cornelia Braun, Johannes Camp, Aleš Janda, Winfried V Kern, Anne-Maria Müller, Katarina Stete, Siegbert R Rieg, Berit Lange
BACKGROUND: Limited evidence on utilisation of health care by recently arrived asylum seekers and refugees in high-income countries is available. This study aims to describe the implementation of an integrated care facility (ICF) in an initial reception centre and measure the utilisation of care and the influence of operational parameters. METHODS: In a retrospective cohort study design, using medical records, we followed inhabitants of a reception centre in Germany between 11...
2024: PloS One
https://read.qxmd.com/read/38635507/gender-distribution-of-top-doctors-in-otolaryngology-head-and-neck-surgery
#3
JOURNAL ARTICLE
Lauren A DiNardo, Alyssa D Reese, Maya Raghavan, Meagan Sullivan, Michele M Carr
INTRODUCTION: Our study seeks to understand the profiles of otolaryngologists selected by Castle Connolly's Top Doctor list and how this compares to the entire field of otolaryngology. METHODS: Top Doctor lists published in Castle Connolly affiliated magazines were analyzed for Otolaryngology, Otolaryngology/Facial Plastic Surgery, or Pediatric Otolaryngology physicians. Only lists published in 2021 or representing the 2021 Top Doctor lists were analyzed. Of the total 39 partnered magazines, 27 met our criteria...
2024: PloS One
https://read.qxmd.com/read/38635005/predictors-of-30-day-recurrent-emergency-department-visits-for-hyperglycemia-in-patients-with-types-1-and-2-diabetes-a-population-based-cohort-study
#4
JOURNAL ARTICLE
Justin W Yan, Branka Vujcic, Britney N Le, Kristine Van Aarsen, Tom Chen, Fardowsa Halane, Kristin K Clemens
OBJECTIVES: This study's aims were to describe the outcomes of patients with diabetes presenting with their first ED visit for hyperglycemia, and to identify predictors of recurrent ED visits for hyperglycemia. METHODS: Using linked databases, we conducted a population-based cohort study of adult and pediatric patients with types 1 and 2 diabetes presenting with a first ED visit for hyperglycemia from April 2010 to March 2020 in Ontario, Canada. We determined the proportion of patients with a recurrent ED visit for hyperglycemia within 30 days of the index visit...
April 18, 2024: CJEM
https://read.qxmd.com/read/38633942/ocular-myasthenia-gravis-as-unilateral-ptosis-and-external-ophthalmoplegia-a-case-report
#5
Shafiq Tanveer, Asna Tahir, Obaid Ahmad, Kainat Bibi, Samreen Khan
Myasthenia gravis (MG) is an autoimmune disorder characterized by fluctuating weakness and fatigue in ocular, bulbar, limb, or respiratory muscles. Initially, more than half of MG patients experience isolated ocular symptoms, such as ptosis, diplopia, or muscle paresis. This case report presents a unique occurrence of MG in a four-year-old female, showcasing a two-year history of sudden onset, persistent yet fluctuating unilateral ptosis accompanied by exo-deviation and adduction deficit in the right eye...
March 2024: Curēus
https://read.qxmd.com/read/38630477/clinician-burnout-and-effectiveness-of-guideline-recommended-psychotherapies
#6
JOURNAL ARTICLE
Nina A Sayer, Adam Kaplan, David B Nelson, Shannon Wiltsey Stirman, Craig S Rosen
IMPORTANCE: Clinician burnout has been associated with clinician outcomes, but the association with patient outcomes remains unclear. OBJECTIVE: To evaluate the association between clinician burnout and the outcomes of patients receiving of guideline-recommended trauma-focused psychotherapies for posttraumatic stress disorder (PTSD). DESIGN, SETTING, AND PARTICIPANTS: This cohort study was set at the US Veterans Affairs Health Care System and included licensed therapists who provided trauma-focused psychotherapies and responded to an online survey between May 2 and October 8, 2019, and their patients who initiated a trauma-focused therapy during the following year...
April 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38629908/incidence-and-risk-factors-for-non-cardiac-syncope-in-a-cohort-of-patients-addressing-an-accredited-arterial-hypertension-center-the-innocent-study
#7
JOURNAL ARTICLE
Filippo Numeroso, Luca Bottaro, Ali Younes, Andrea Ungar, Aderville Cabassi
BACKGROUND: Hypotensive susceptibility in hypertensive patients could facilitate orthostatic hypotension, syncope and fall. The aim of this study was to identify incidence, clinical form, complications and risk factors for non-cardiac syncope in a cohort of hypertensive patients. METHODS: This is an observational, case-controlled, retrospective study carried out on 168 patients, evaluated at the Hypertension Center of the University Hospital of Parma (Italy). Based on the presence of episodes of syncope during the six months prior to enrolment, we identified cases and controls and then we compared them to personal data, comorbidities, current drug regimens, presence of orthostatic hypotension, office and ambulatory blood pressure monitoring (ABPM) blood pressure (BP) values...
April 17, 2024: Minerva Medica
https://read.qxmd.com/read/38628528/aortoiliac-occlusion-mimicking-cauda-equina-syndrome-a-diagnostic-dilemma-a-case-report-and-review-of-the-literature
#8
Abdulaziz Alomayri, Ali A Basalamah, Alwaleed Abdulrahman Alsaleh, Sultan Alreshood, Abdulrahman Aldakkan
BACKGROUND: Cauda equina syndrome (CES) is a consequence of a variety of etiologies. CES is most commonly due to compression of the thecal sac and nerve roots by a massive disc herniation. However, it rarely presents secondary to aortic occlusion. Aortoiliac occlusive disorder is usually associated with chronic claudication, erectile dysfunction, and diminished lower limb pulses. Acute aortic occlusion, however, is associated with serious complications such as spinal cord infarction and ischemia...
2024: Surgical Neurology International
https://read.qxmd.com/read/38628378/public-perception-in-saudi-arabia-toward-herpes-zoster-and-its-vaccination-a-cross-sectional-study
#9
JOURNAL ARTICLE
Mohammad S AlKhowailed, Hatim M Alotaibi, Amwaj S Aljurays, Reem A Mohammad, Ghadeer M Alqahtani, Waleed Al Abdulmonem, Ahmed Alhumidi, Homaidan T Alhomaidan, Fuhaid M Alqossayir
Background Herpes zoster (HZ) or shingles, arises from the reactivation of the varicella zoster virus (VZV), mainly affecting older and immunocompromised individuals. Despite the efficacy of vaccines, vaccination rates in Saudi Arabia are low. Thus, this study aimed to assess the knowledge, attitude, and practice of the Saudi Arabian population toward HZ and its vaccination. Methods An observational cross-sectional study was carried out to evaluate the public perception in Saudi Arabia toward HZ and its vaccination, during the period from January to March 2024...
April 2024: Curēus
https://read.qxmd.com/read/38627993/age-stratified-profiles-and-outcomes-of-patients-with-heart-failure-with-preserved-ejection-fraction
#10
JOURNAL ARTICLE
Shinsuke Yamanaka, Kotaro Nochioka, Hideka Hayashi, Takashi Shiroto, Jun Takahashi, Satoshi Miyata, Satoshi Yasuda, Hiroaki Shimokawa
AIMS: This study aimed to elucidate age-stratified clinical profiles and outcomes in patients with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HFpEF). METHODS AND RESULTS: The Chronic Heart Failure Registry and Analysis in the Tohoku District-2 (CHART-2) Study included 2824 consecutive HFpEF patients with LVEF ≥ 50% (mean age 69.0 ± 12.3 years; 67.7% male) with a median follow-up of 9.8 years...
April 16, 2024: ESC Heart Failure
https://read.qxmd.com/read/38627517/risk-of-chronic-obstructive-pulmonary-disease-in-a-large-cohort-of-ontario-canada-workers
#11
JOURNAL ARTICLE
Jeavana Sritharan, Victoria H Arrandale, Tracy L Kirkham, Mamadou Dakouo, Jill S MacLeod, Paul A Demers
Although several occupational exposures have been linked to the risk of COPD; limited data exists on sex-specific differences. This study aimed to identify at-risk occupations and sex differences for COPD risk. Cases were identified in a large surveillance system established through the linkage of former compensation claimants' data (non-COPD claims) to physician visits, ambulatory care data, and hospital inpatient data (1983-2020). Cox proportional hazard models were used to estimate hazard ratios (HRs) and corresponding 95% confidence intervals (CI) for occupation groups (occupation at time of claim), stratified by sex...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38627131/relationship-of-the-novel-scoring-system-for-lower-extremity-venous-thrombosis-with-pulmonary-embolism
#12
JOURNAL ARTICLE
Ahmet Turan Kaya, Burcu Akman
RATIONALE AND OBJECTIVE: To develop a new scoring system, the "Lower extremity venous Doppler ultrasound scoring system" (LEVDUS), to predict the diagnosis of pulmonary embolism (PE) localization in patients with deep vein thrombosis (DVT). METHODS: This single-center retrospective study included 182 patients aged ≥ 18 years. We used scoring according to thrombosis localization and stage in Doppler US. Patients with PE were divided into three categories based on the pulmonary artery (PA) location on CT pulmonary angiography...
April 15, 2024: Academic Radiology
https://read.qxmd.com/read/38626927/respiratory-related-deaths-and-associated-factors-in-alicho-weriro-district-southern-ethiopia-verbal-autopsy-data-analysis
#13
JOURNAL ARTICLE
Netsanet Belete, Sebsibe Tadesse, Mulugeta Hailu
BACKGROUND: Respiratory diseases disproportionately affect people living in resource-limited settings. However, obtaining information that explains respiratory-related deaths has been difficult, mainly due to a lack of medical certification of death and the fact that most deaths occur outside of health institutions. This study aimed to determine the proportion of respiratory-related deaths and identify associated factors in Alicho-Weriro district, southern Ethiopia, using the verbal autopsy method...
April 15, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38623130/clinicians-attitudes-toward-electronic-health-records-in-saudi-arabia
#14
JOURNAL ARTICLE
Tourkiah Alessa
AIM:  This study explored physicians' and nurses' attitudes toward an electronic health record (EHR) system and examined the features and factors that clinicians associated with the implementation of EHR systems. METHODS:  A self-administered anonymous questionnaire with high reliability and validity was adopted from existing research to gather clinicians' attitudes toward the EHR system implemented at King Khalid University Hospital, one of the biggest hospitals in Riyadh, Saudi Arabia...
March 2024: Curēus
https://read.qxmd.com/read/38622789/disease-modifying-therapies-for-sickle-cell-disease-decisional-needs-and-supports-among-adolescents-and-young-adults
#15
JOURNAL ARTICLE
Ke Ding, Benjamin Bear, Erica Sood, Melissa Alderfer, Lori Crosby, Aimee K Hildenbrand
BACKGROUND: Shared decision-making is one promising solution to addressing barriers in use of disease-modifying therapies for adolescents and young adults (AYAs) with sickle cell disease (SCD). A thorough understanding of decisional needs can guide the development of decisional supports and promote shared decision-making. PROCEDURE: Informed by the Ottawa Decision Support Framework (ODSF), we conducted a qualitative analysis to assess decisional needs and supports reported by AYAs with SCD, their caregivers, and healthcare providers...
April 15, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38621700/a-population-based-study-of-covid-19-mortality-risk-in-us-cancer-patients
#16
JOURNAL ARTICLE
Kyle A Mani, Xue Wu, Daniel E Spratt, Ming Wang, Nicholas G Zaorsky
BACKGROUND: In this study, we provide the largest analysis to date of a US-based cancer cohort to characterize death from COVID-19. METHODS: A total of 4,020,669 patients across 15 subtypes living with cancer in 2020 and included in the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database were abstracted. We investigated prognostic factors for death due to COVID-19 using a cox proportional hazards model and calculated hazard ratios (HRs)...
April 15, 2024: Journal of the National Cancer Institute
https://read.qxmd.com/read/38619840/ai-generated-draft-replies-integrated-into-health-records-and-physicians-electronic-communication
#17
JOURNAL ARTICLE
Ming Tai-Seale, Sally L Baxter, Florin Vaida, Amanda Walker, Amy M Sitapati, Chad Osborne, Joseph Diaz, Nimit Desai, Sophie Webb, Gregory Polston, Teresa Helsten, Erin Gross, Jessica Thackaberry, Ammar Mandvi, Dustin Lillie, Steve Li, Geneen Gin, Suraj Achar, Heather Hofflich, Christopher Sharp, Marlene Millen, Christopher A Longhurst
IMPORTANCE: Timely tests are warranted to assess the association between generative artificial intelligence (GenAI) use and physicians' work efforts. OBJECTIVE: To investigate the association between GenAI-drafted replies for patient messages and physician time spent on answering messages and the length of replies. DESIGN, SETTING, AND PARTICIPANTS: Randomized waiting list quality improvement (QI) study from June to August 2023 in an academic health system...
April 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38618688/risk-factors-associated-with-a-history-of-iliotibial-band-syndrome-hitbs-in-distance-runners-a-cross-sectional-study-in-76-654-race-entrants-a-safer-xxxiii-study
#18
JOURNAL ARTICLE
Jandre V Marais, Audrey Jansen van Rensburg, Martin P Schwellnus, Esme Jordaan, Pieter Boer
BACKGROUND: Despite the numerous health benefits of distance running, it is also associated with the development of 'gradual onset running-related injuries' (GORRIs) one of which is Iliotibial Band Syndrome (ITBS). Novel risk factors associated with a history of ITBS (hITBS) have not been described in a large cohort of distance runners. OBJECTIVE: To identify risk factors associated with hITBS in distance runners. DESIGN: Descriptive cross-sectional study...
April 15, 2024: Physician and Sportsmedicine
https://read.qxmd.com/read/38618578/national-and-international-comparisons-of-gynecological-research-in-germany-based-on-a-bibliometric-analysis-of-publications
#19
JOURNAL ARTICLE
Bertram Häussler, Barbara Schmalfeldt, Senta Häussler, Angela Köninger, Stefan Loos, Gert Naumann, Anton Scharl, Christian J Thaler, Martin Weiss, Martin Albrecht
BACKGROUND: Recent years have seen a considerable shift from male doctors to female doctors in the field of gynecology. Female doctors are traditionally more involved with planning and maintaining their family. For gynecology, this could be associated with a risk that research activities will decrease, particularly if results are published in scientific journals. METHODS: In view of this shift, a comparative observational study was carried for 2022 in which 1306 publications were matched to 1786 female and male doctors reported on the websites of the 44 locations of university gynecology departments in Germany...
April 2024: Geburtshilfe und Frauenheilkunde
https://read.qxmd.com/read/38618465/roux-en-y-gastric-bypass-and-the-clinical-manifestations-of-vitamin-deficiencies-case-report-and-literature-review
#20
Trystan A Innes, Samuel R Massey, Hezborn M Magacha, Venkata Vedantam, Neethu Vedantam
This case outlines the complications of Roux-en-Y gastric bypass surgery (RYGBS) and demonstrates clinical manifestations of several vitamin deficiencies. We present a 45-year-old female patient who was admitted to our hospital with generalized weakness, anasarca, hypotension, and failure to thrive, a year after she had her RYGBS. After the procedure, she had nausea, vomiting, and diarrhea with progressive inability to tolerate any oral intake. Subsequently, the patient lost over 200 pounds and got bedridden...
March 2024: Curēus
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