keyword
MENU ▼
Read by QxMD icon Read
search

Split-dose preparations

keyword
https://www.readbyqxmd.com/read/28291237/comparison-of-two-intensive-bowel-cleansing-regimens-in-patients-with-previous-poor-bowel-preparation-a-randomized-controlled-study
#1
Antonio Z Gimeno-García, Goretti Hernandez, Ana Aldea, David Nicolás-Pérez, Alejandro Jiménez, Marta Carrillo, Vanesa Felipe, Onofre Alarcón-Fernández, Manuel Hernandez-Guerra, Rafael Romero, Inmaculada Alonso, Yanira Gonzalez, Zaida Adrian, Miguel Moreno, Laura Ramos, Enrique Quintero
OBJECTIVES: Inadequate bowel cleansing is a major burden for endoscopy units. The aim of this study was to compare two intensive bowel cleansing regimens in patients with previous colonoscopy with inadequate bowel preparation. METHODS: Patients with inadequate cleansing at index colonoscopy were randomized to 4-L split-dose polyethylene-glycol (PEG) regimen vs. 2-L split-dose PEG plus ascorbic acid (PEG+Asc) regimen. All individuals underwent a 3-day low-residue diet and received 10 mg of bisacodyl, the day before colonoscopy...
March 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28282689/water-exchange-for-screening-colonoscopy-increases-adenoma-detection-rate-a-multicenter-double-blinded-randomized-controlled-trial
#2
Sergio Cadoni, Přemysl Falt, Emanuele Rondonotti, Franco Radaelli, Petr Fojtik, Paolo Gallittu, Mauro Liggi, Arnaldo Amato, Silvia Paggi, Vit Smajstrla, Ondřej Urban, Matteo Erriu, Malcolm Koo, Felix W Leung
Background and study aims Single-center studies, which were retrospective and/or involved unblinded colonoscopists, have suggested that water exchange, but not water immersion, compared with air insufflation significantly increases the adenoma detection rate (ADR), particularly in the proximal and right colon. Head-to-head comparison of the three techniques with ADR as primary outcome and blinded colonoscopists has not been reported to date. In a randomized controlled trial with blinded colonoscopists, we aimed to evaluate the impact of the three insertion techniques on ADR...
March 10, 2017: Endoscopy
https://www.readbyqxmd.com/read/28246476/is-a-split-dose-regimen-of-2-l-polyethylene-glycol-plus-ascorbic-acid-tolerable-for-colonoscopy-in-an-early-morning-visit-to-a-comprehensive-medical-check-up
#3
Ji Yeon Seo, Changhyun Lee, Eun Hyo Jin, Mi Hyun Yun, Joo Hyun Lim, Hae Yeon Kang, Jong In Yang, Su Jin Chung, Sun Young Yang, Joo Sung Kim
AIM: To evaluate the effectiveness and tolerability of a split-dose 2 L polyethylene glycol (PEG)/ascorbic acid (AA) regimen for healthy examinees who visited for comprehensive medical check-up in the early morning. METHODS: From February 2015 to March 2015, examinees of average risk who were scheduled for a colonoscopy in the morning were retrospectively enrolled. RESULTS: The 189 examinees were divided into split-dose and non-split-dose groups...
February 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28236800/impact-of-the-new-handling-recommendations-for-hazardous-drugs-in-a-hospital-pharmacy-service
#4
Beatriz G García-Alcántara, Catalina Perelló Alomar, Elena Moreno Centeno, Pilar Modamio, Eduardo L Mariño, Olga Delgado Sánchez
OBJECTIVE: To describe the actions taken by the Pharmacy Unit in a tertiary hospital in order to adapt to the recommendations established by NIOSH 2014 for handling Hazardous Drugs. Method: A retrospective observational study. A list was prepared including all hazardous drugs according to NIOSH 2014 that were available at the hospital as marketed or foreign drugs, or used in clinical trials, and there was a review of the processes of acquisition, repackaging, preparation, circuits, organizational, dispensing and identification...
March 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28188978/split-dose-bowel-preparation-with-polyethylene-glycol-for-colonoscopy-performed-under-propofol-sedation-is-there-an-optimal-timing
#5
Alaa Alghamry, Sureshkumar K Ponnuswamy, Aditya Agarwal, Hadi Moattar, Stephanie T Yerkovich, Ann E Vandeleur, James Thomas, John Croese, Tony Rahman, Ruth Hodgson
AIM: Aspiration risk, especially with propofol sedation, remains a concern with split-dose bowel preparation using polyethylene glycol, which involves up to one liter of preparation intake close to the procedure time. We aim to identify the ideal timing of bowel preparation that achieves optimal colon cleansing with no increased risk of aspiration in all patients undergoing combined esophagogastroduodenoscopy (EGD) and colonoscopy with propofol sedation. METHODS: We prospectively recruited 892 consecutive patients undergoing simultaneous EGD and colonoscopy...
February 11, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28055031/a-customized-mobile-application-in-colonoscopy-preparation-a-randomized-controlled-trial
#6
Ala I Sharara, Jean M Chalhoub, Maya Beydoun, Rani H Shayto, Hamed Chehab, Ali H Harb, Fadi H Mourad, Fayez S Sarkis
OBJECTIVES: Adherence with diet and prescribed purgative is essential for proper cleansing with low-volume bowel preparations. The aim of this work was to assess the effect of a customized mobile application (App) on adherence and quality of bowel preparation. METHODS: One hundred and sixty (160) eligible patients scheduled for elective colonoscopy were randomly assigned to paper (control) or App-based instructions. The preparation consisted of low-fiber diet for 2 days, clear fluids for one day and split-dose sodium picosulfate/magnesium citrate (SPS)...
January 5, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/27935163/manipulating-tablets-and-capsules-given-to-hospitalised-children-in-norway-is-common-practice
#7
Kathrin Bjerknes, Silje Bøyum, Solveig Kristensen, Jørgen Brustugun, Siri Wang
AIM: This study provided an overview of manipulating oral medicines given to hospitalised children and evaluated this practice in two hospitals. It focused on the type of manipulation and the dosage forms that were manipulated. METHOD: This was a cross-sectional, prospective study, carried out on the paediatric wards at two Norwegian hospitals for four weeks in 2013. A medicine was said to have been manipulated if it was not administered as described in the Norwegian summary of product characteristics...
December 9, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27911481/photoluminescence-and-thermoluminescence-of-k2-mg-so4-2-eu-and-evaluation-of-its-kinetic-parameters
#8
Archana Deshpande, N S Dhoble, S C Gedam, S J Dhoble
The K2 Mg(SO4 )2 :Eu phosphor, synthesized by a solid-state diffusion method, was studied for its photoluminescence (PL) and thermoluminescence (TL) characteristics. The X-ray diffraction (XRD) pattern of the material was matched with the standard JCPDF No. 36-1499. For PL characteristics, K2 Mg(SO4 )2 :Eu(2)(+) showed an emission peak at 474 nm when excited at 340 nm, while it showed Eu(3)(+) emission at 580 nm, and 594 nm splitting at 613 nm and 618 nm for an excitation of 396 nm wavelength due to radiative transitions from (5) D0 to (7) Fj (j = 0, 1, 2, 3)...
December 2, 2016: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/27889546/comparison-of-a-split-dose-bowel-preparation-with-2l-polyethylene-glycol-plus-ascorbic-acid-and-1l-polyethylene-glycol-plus-ascorbic-acid-and-bisacodyl-before-colonoscopy
#9
Seung Hun Kang, Yoon Tae Jeen, Jae Hyung Lee, In Kyung Yoo, Jae Min Lee, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Hong Sik Lee, Hoon Jai Chun, Chang Duck Kim
BACKGROUND AND AIMS: Recently a low-volume polyethylene glycol containing ascorbic acid (PEG-Asc) formulation has proven as safe and effective as traditional 4L PEG solutions for colonoscopy preparation. However, currently available aqueous purgative formulations are poorly tolerated. The aim of this study was to compare a split-dose 2L PEG-Asc and a 1L PEG-Asc with bisacodyl (10 mg) formulation to determine the quality of bowel cleansing and patient tolerability. METHODS: A single-center, randomized, observer-blinded study was performed between May 2015 and September 2015...
November 23, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27864718/phosphate-tablets-or-polyethylene-glycol-for-preparation-to-colonoscopy-a-multicentre-non-inferiority-randomized-controlled-trial
#10
Stanislas Chaussade, Christoph Schmöcker, Pierre Toulemonde, Miguel Muñoz-Navas, Valérie O'Mahony, Franck Henri
BACKGROUND: Adequate bowel preparation is a crucial step in colonoscopy procedure and has been identified as the cornerstone of a quality colonoscopy. Polyethylene glycol (PEG) for bowel cleansing still had up to 10 % unprepared colon. AIM: We herein compare efficacy, acceptability, tolerance and safety of sodium phosphate (NaP) tablets and split-dose PEG for bowel cleansing. PATIENTS AND METHODS: A prospective non-inferiority randomized trial was performed and registered on www...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27770378/predictors-of-suboptimal-bowel-preparation-using-3-l-of-polyethylene-glycol-for-an-outpatient-colonoscopy-a-prospective-observational-study
#11
Chi-Liang Cheng, Nai-Jen Liu, Jui-Hsiang Tang, Yen-Lin Kuo, Hsiang-Ling Hung, Yi-Ning Tsui, Bai-Ping Lee, Cheng-Hui Lin
BACKGROUND: A 3-l polyethylene glycol (PEG) solution provided better bowel cleansing quality than a 2-l solution for outpatient colonoscopy. Predictors of suboptimal preparation using a 3-l PEG have not been previously reported. AIMS: To investigate the possible predictors of suboptimal bowel preparation using 3-l of PEG. METHODS: We analyzed a database of 1404 consecutive colonoscopies during a 27-month period at a community hospital. A split-dose PEG regimen was provided for morning colonoscopies, and a same-day PEG regimen was provided for afternoon colonoscopies...
October 21, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27753434/video-on-diet-before-outpatient-colonoscopy-does-not-improve-quality-of-bowel-preparation-a-prospective-randomized-controlled-trial
#12
Sean C Rice, Tina Higginbotham, Melanie J Dean, James C Slaughter, Patrick S Yachimski, Keith L Obstein
OBJECTIVES: Successful outpatient colonoscopy (CLS) depends on many factors including the quality of a patient's bowel preparation. Although education on consumption of the pre-CLS purgative can improve bowel preparation quality, no study has evaluated dietary education alone. We have created an educational video on pre-CLS dietary instructions to determine whether dietary education would improve outpatient bowel preparation quality. METHODS: A prospective randomized, blinded, controlled study of patients undergoing outpatient CLS was performed...
November 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27736795/preparation-regimen-is-more-important-than-patient-related-factors-a-randomized-trial-comparing-a-standard-bowel-preparation-before-colonoscopy-with-an-individualized-approach
#13
T Voiosu, Alina Tanţău, A Voiosu, Andreea Benguş, Cristina Mocanu, Bianca Smarandache, C Baicuş, Ioana Vişovan, B Mateescu
BACKGROUND: Optimal bowel preparation is one of the most important factors affecting the quality of colonoscopy. Several patient-related factors are known to influence the quality of bowel cleansing but randomized trials in this area are lacking. We aimed to compare an individualized bowel prep strategy based on patient characteristics to a standard preparation regimen. MATERIAL AND METHODS: We conducted an endoscopist-blinded multicenter randomized control-trial...
March 1, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/27701933/technical-interventions-to-increase-adenoma-detection-rate-in-colonoscopy
#14
Emanuele Rondonotti, Alida Andrealli, Arnaldo Amato, Silvia Paggi, Clara Benedetta Conti, Giancarlo Spinzi, Franco Radaelli
Adenoma detection rate (ADR) is the most robust colonoscopy quality metric and clinical studies have adopted it as the ideal method to assess the impact of technical interventions. Areas covered: We reviewed papers focusing on the impact of colonoscopy technical issues on ADR, including withdrawal time and technique, second evaluation of the right colon, patient positional changes, gastrointestinal assistant participation during colonoscopy, water-aided technique, optimization of bowel preparation and antispasmodic administration...
December 2016: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27697632/improving-adjuvanticity-of-quaternized-chitosan-based-microgels-for-h5n1-split-vaccine-by-tailoring-the-particle-properties-to-achieve-antigen-dose-sparing-effect
#15
Yue-Qi Wang, Qing-Ze Fan, Yan Liu, Hua Yue, Xiao-Wei Ma, Jie Wu, Guang-Hui Ma, Zhi-Guo Su
In this study, we developed the quaternized chitosan microgels without chemical crosslinking as an adjuvant of H5N1 split vaccine. The microgels with pH-sensitivity, positive surface charge and good biocompatibility, have been demonstrated in favor of enhancing both humoral and cellular immune response. However, the detailed mechanism of the chitosan-based microgels to enhance antigen specific immune responses remains unclear. Therefore, we prepared the quaternized chitosan microgels with well defined quaternization degrees (QDs, 20-80%) and particle sizes (800nm-5μm) by the premix membrane emulsification technique, and investigated the effect of quaternization degree (QD) and size on the adjuvanticity of microgels...
December 30, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27689192/superiority-of-a-split-dose-regimen-of-sodium-picosulfate-magnesium-citrate-spmc-in-comparison-to-a-prior-day-schedule-am-pm-for-colonoscopy-preparation-a-randomized-single-blinded-study
#16
RANDOMIZED CONTROLLED TRIAL
Christian Schulz, Joachim Müller, Joachim Sauter, Stephan Miehlke, Christoph Schmöcker, Dirk Hartmann, Peter Malfertheiner, Carlos Badiola
BACKGROUND AND AIMS: Split-dose regimens are generally recommended for bowel cleansers. However, other regimens still remain in the summary of product characteristics of some bowel cleansers in Europe. The aim of this study is to compare the efficacy and safety of a split-dose regimen of sodium picosulfate/magnesium citrate (SPMC) with a prior-day schedule (AM/PM). METHODS: Multicenter, randomized (EudraCT no. 2013-001620-20), endoscopist-blinded, parallel study, carried out in subjects 18 years or older undergoing elective colonoscopy...
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27553205/low-volume-polyethylene-glycol-with-ascorbic-acid-for-colonoscopy-preparation-in-elderly-patients-a-randomized-multicenter-study
#17
Yoon Suk Jung, Chang Kyun Lee, Chang Soo Eun, Dong Il Park, Dong Soo Han, Hyo Jong Kim
BACKGROUND: Minimal data exist regarding the use of low-volume purgatives for elderly (≥65 years) patients. We aimed to investigate the bowel-cleansing efficacy and patient tolerability of split-dose 2 liters (L)-polyethylene glycol with ascorbic acid (2L-PEGA) in elderly outpatients undergoing colonoscopy. METHODS: Patients who underwent morning colonoscopies were randomly assigned to one of 3 arms: single-dose 4L-PEG on the day before colonoscopy; split-dose 4L-PEG; or split-dose 2L-PEGA...
2016: Digestion
https://www.readbyqxmd.com/read/27513409/the-efficacy-of-a-through-the-scope-sodium-phosphate-solution-with-completion-colonoscopy-on-the-same-day-as-a-salvage-option-for-inadequate-bowel-cleansing
#18
Mehmet İbiş, İbrahim Koral Önal, Mehmet Arhan, Tarkan Karakan, Eylem Karatay, Özlem Gül Utku, Harun Erdal, İbrahim Doğan
BACKGROUND/AIM: The aim of this study was to investigate the efficacy of a through- the-scope sodium phosphate solution with completion colonoscopy on the same day as a salvage option for inadequate bowel preparation. MATERIALS AND METHODS: All participants were instructed to eat a low residual diet for 3 days before the scheduled colonoscopy and a clear liquid diet 18 h before the colonoscopy. The patients were asked to take split doses of an oral sennoside solution at 1800 and 2200 in the evening before the colonoscopy...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27494637/nutritional-value-of-raw-and-micronised-field-beans-vicia-faba-l-var-minor-with-and-without-enzyme-supplementation-containing-tannase-for-growing-chickens
#19
Jalil Mahmwd Abdulla, Stephen Paul Rose, Alexander Mackay Mackenzie, Sonya Georgieva Ivanova, Genoveva Petrova Staykova, Vasil Radoslavov Pirgozliev
An experiment examined the effects of two field bean cultivar samples with different tannin contents, the effect of heat treatment (micronising) and the effect of dietary supplementation of a proprietary enzyme preparation containing tannase, pectinase, and xylanase activities on metabolisable energy (ME), total tract dry matter digestibility (DMD) and ether extract digestibility (EED), nitrogen retention (NR), tannin degradability, gastrointestinal tract (GIT) development, and endogenous mucin losses excretion in broiler chickens...
October 2016: Archives of Animal Nutrition
https://www.readbyqxmd.com/read/27490086/efficacy-of-a-multifactorial-strategy-for-bowel-preparation-in-diabetic-patients-undergoing-colonoscopy-a-randomized-trial
#20
Marco Antonio Alvarez-Gonzalez, Juana A Flores-Le Roux, Agustin Seoane, Juan Pedro-Botet, Laura Carot, Agnés Fernandez-Clotet, Agnés Raga, Miguel A Pantaleon, Luis Barranco, Felipe Bory, Vicente Lorenzo-Zuñiga
Background and study aims: Previous studies have reported that diabetes mellitus is an independent risk factor for inadequate bowel preparation. Current guidelines do not recommend a specific preparation for this patient population. The aims of this study were to assess the efficacy, safety, and tolerability of an adapted preparation protocol for colon cleansing in patients with type 2 diabetes mellitus. Patients and methods: This randomized, single-blind, parallel group, superiority trial compared a conventional bowel preparation protocol (CBP) with a diabetes-specific preparation protocol (DSP)...
November 2016: Endoscopy
keyword
keyword
79812
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"