Yen-I Chen, Anand Sahai, Gianfranco Donatelli, Eric Lam, Nauzer Forbes, Jeffrey Mosko, Sarto C Paquin, Fergal Donnellan, Avijit Chatterjee, Jennifer Telford, Corey Miller, Etienne Desilets, Gurpal Sandha, Sana Kenshil, Rachid Mohamed, Gary May, Ian Gan, Jeffrey Barkun, Natalia Calo, Abrar Nawawi, Gad Friedman, Albert Cohen, Thibaut Maniere, Prosanto Chaudhury, Peter Metrakos, George Zogopoulos, Ali Bessissow, Jad Abou Khalil, Vicky Baffis, Kevin Waschke, Josee Parent, Constantine Soulellis, Mouen Khashab, Rastislav Kunda, Olivia Geraci, Myriam Martel, Kevin Schwartzman, Julio F Fiore, Elham Rahme, Alan Barkun
BACKGROUND AND AIMS: Endosonography-guided choledochoduodenostomy with a lumen-apposing metal stent (EUS-CDS) is a promising modality for the management of malignant distal biliary obstruction (MDBO) with potential for better stent patency. We compared its outcomes with endoscopic retrograde cholangiopancreatography with metal stenting (ERCP-M). METHODS: In this multicenter, randomized, controlled trial, we recruited patients with MDBO secondary to borderline resectable, locally advanced, or unresectable peri-ampullary cancers across 10 Canadian and one French institution(s)...
August 5, 2023: Gastroenterology