keyword
MENU ▼
Read by QxMD icon Read
search

Lipomatic

keyword
https://www.readbyqxmd.com/read/29142168/background-data-on-nod-shi-scid-il-2r%C3%AE-null-mice-nog-mice
#1
Kenichiro Kasahara, Yachiyo Fukunaga, Saori Igura, Rie Andoh, Tsubasa Saito, Isamu Suzuki, Hiroyuki Kanemitsu, Daisuke Suzuki, Ken Goto, Daichi Nakamura, Masahiro Mochizuki, Masahiko Yasuda, Ryo Inoue, Kazutoshi Tamura, Mariko Nagatani
To obtain background data of NOD/Shi-scid IL-2Rγ(null) (NOG) mice, severely immunedeficient mice, a total of 120 animals were examined at 7, 26 and 52 weeks-old (20 mice/sex/group). The survival rate at 52 weeks-old was 95% (19/20) in both sexes. Clinically, circling behavior in one direction along the cage wall was observed in males after 8 weeks and females after 47 weeks-old, and hunchback position was found in males after 32 weeks-old. Hematologically, lymphocyte count markedly decreased at all ages, while white blood cell count increased in several mice at 52 weeks-old...
2017: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/29129155/transgenerational-inheritance-of-familial-lipomyelomeningocele
#2
Thomas Larrew, Ramin Eskandari, Kenton R Holden, Amy Chen, Catherine J Spellicy, Julie R Jones, Jennifer A Lee, Michael J Lyons
Lipomyelomeningocele is a type of neural tube defect characterized by lipomatous tissue causing a defect in the vertebrae, infiltrating the dura, and tethering the spinal cord. Despite significant neurologic consequences, the underlying etiology remains poorly understood. We present a father and son with remarkably similar presentations of lipomyelomeningocele. Genetic testing did not reveal an underlying cause but whole exome sequencing identified variants in the ARHGAP29 and RADIL genes in the proband and his affected father...
December 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/29128479/adipocyte-size-variability-in-benign-and-malignant-lipomatous-tumors-and-morphologic-mimics-a-quantitative-definition-using-digital-pathology
#3
Gregory R Bean, Kwun Wah Wen, Andrew E Horvai
Among well-differentiated lipomatous lesions, variability in adipocyte size has been proposed as a morphologic feature of malignancy. Specifically, normal adipose tissue and benign lipomas tend to contain adipocytes of uniform size, whereas atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) are described as containing adipocytes with a conspicuous variation in cell size. However, this proposed variance has never been objectively, quantitatively correlated with diagnosis. Using whole slide scanning combined with semiautomated digital image analysis, we aimed to quantitatively test the hypothesis that variance in adipocyte size is a feature of malignancy in well-differentiated lipomatous tumors...
November 8, 2017: Human Pathology
https://www.readbyqxmd.com/read/29123893/a-case-of-omental-herniation-through-the-esophageal-hiatus-successfully-treated-by-laparoscopic-surgery
#4
Koichiro Sueyoshi, Yoshiaki Inoue, Yuka Sumi, Ken Okamoto, Daisuke Azuma, Seiichiro Yoshikawa, Masaki Fukunaga, Hiroshi Tanaka
Case: We report a rare case of omental herniation through the esophageal hiatus. A 46-year-old man visited our emergency department complaining of epigastralgia. Abdominal examination revealed muscular defense and rebound tenderness in his upper abdomen. A computed tomography scan showed a fat density mass in the posterior mediastinum. A laparoscopic operation was carried out under the diagnosis of omental herniation through the esophageal hiatus. Outcome: Abdominal pain disappeared dramatically after the operation...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29089714/multiple-lipomatous-hemangiopericytomas-in-the-foot-and-ankle
#5
Vivek Pandey, Sandesh Madi, Monish Malhotra, Vidya Monappa
Since its first description, the diagnosis and terminology of hemangiopericytoma have been in controversy. We report perhaps the first case of multiple lipomatous hemangiopericytoma occurring in the foot and ankle region.
October 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29068974/an-atypical-lipomatous-tumor-mimicking-a-giant-fibrovascular-polyp-of-the-hypopharynx-a-case-report
#6
Khrystyna E Ioanidis, Stephanie Danielle MacNeil, Keng Yeow Tay, Bret Wehrli
RATIONALE: Giant fibrovascular polyps (GFVPs) found in the hypopharynx are exceedingly rare. These are benign tumors which are identified by CT or MRI and usually treated based on symptoms. Even more rarely, pathology may identify one of these masses as an atypical lipomatous tumor (ALT). This paper will present a case of an ALT of the hypopharynx that was originally classified as a GFVP, highlighting the difficulty in distinguishing between them and the importance of making the correct diagnosis...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29058949/lipomas-of-the-brachial-plexus-a-case-series-and-review-of-the-literature
#7
Alexander Graf, Kai Yang, David King, William Dzwierzynski, James Sanger, Patrick Hettinger
BACKGROUND: Lipomas are common benign tumors. When they develop in proximity to peripheral nerves, they can cause neurologic symptoms secondary to mass effect. Previous reports have shown symptom resolution after removal of lipomas compressing various upper extremity peripheral nerves. However, brachial plexus lipomas are relatively rare. Our multidisciplinary experience with brachial plexus lipoma resection is reviewed in the largest case series to date. METHODS: A retrospective chart review of all patients undergoing resection of brachial plexus lipomatous tumors between 2006 and 2016 was performed...
October 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29025583/a-rare-case-of-pediatric-lipoma-with-t-9-12-p22-q14-and-evidence-of-hmga2-nfib-gene-fusion
#8
Melanie Lacaria, Dina El Demellawy, Jean McGowan-Jordan
Lipoma is a benign tumor, typically of adulthood, with characteristic cytogenetic findings, including rearrangement of 12q13-15; these rearrangements often lead to the fusion of the HMGA2 gene at this locus to the transcriptional regulatory domain of its fusion partner, resulting in neomorphic activity that presumably facilitates the neoplastic process. Herein, we report a rare case of pediatric lipoma with t(9;12)(p22;q14) and evidence of HMGA2-NFIB gene fusion in a 9 year-old boy. This case provides further evidence of the link between NFIB rearrangement and early-onset, deep-seated lipomatous tumors...
October 2017: Cancer Genetics
https://www.readbyqxmd.com/read/29019868/vulvar-myxoid-liposarcoma-an-extremely-rare-diagnosis-a-case-report-and-review-of-literature
#9
Ligia Redroban, Nelson Montalvo
Malignant lipomatous tumors of the vulva are an extremely rare entity. We report the case of a 53-year-old patient with a nodule on her right labium majus whose histological and immunohistochemical profile (S100 and p16) confirmed a diagnosis of vulvar myxoid liposarcoma.
October 10, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28984116/cerebellar-liponeurocytoma-with-atypical-histological-features-a-rare-example-of-a-glioneuronal-tumor
#10
Blanka Hermann, Michal Woznica, Wojciech Kloc, Piotr Borkowski, Witold Libionka, Ewa Izycka-Swieszewska
We present a case of a rare neoplasm in a 77-year-old woman with previous oncological history, who developed a rapid onset of cerebellar symptoms. The neuroimaging detected a posterior fossa tumor suspected of meningioma which was completely resected soon after. Histologically the neoplasm had two components with different immunophenotype. One constituent was lobular, composed of monotonous mitotically active round cells with a predominant neuronal profile. The second, astrocytic component contained lipomatous cells intermixed with larger gemistocytic astrocytes...
2017: Folia Neuropathologica
https://www.readbyqxmd.com/read/28981153/pleomorphic-fibroma-of-the-skin-with-mdm2-immunoreactivity-a-potential-diagnostic-pitfall
#11
Mehrnoosh Tashakori, Jason Pimentel, Brooke E Howitt, Jessica Sanchez, Susan Michalowski, Dhananjay Chitale, Adrian H Ormsby, Sean R Williamson
Pleomorphic fibroma is a rare benign cutaneous neoplasm characterized by spindle-shaped cells and multinucleated giant cells scattered throughout collagenous stroma. These morphologic features can lead to diagnostic confusion, including atypical lipomatous tumor as one consideration. In contrast to atypical lipomatous tumor, previous studies have found pleomorphic fibroma to be negative for MDM2 immunohistochemical staining and MDM2 gene amplification. Here, we present a case of pleomorphic fibroma of skin with nuclear MDM2 immunoreactivity in the absence of MDM2 gene amplification, underscoring the superiority of fluorescence in situ hybridization as a diagnostic test in this differential diagnosis...
October 5, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28977976/clinical-features-and-prognosis-for-intraventricular-liponeurocytoma
#12
Nini Xu, Jinxiu Cai, Jiang Du, Rong Yang, Huachen Zhu, Peiyi Gao, Jian Zhou, Xiaofeng Li
Cerebellar liponeurocytoma is a rare central nervous system tumor, we investigate its biological behaviors and clinical prognosis to improve the understanding of this tumor. We retrospectively analyzed the clinical, radiological and histopathological findings as well as follow-up data of two patients with intraventricular liponeurocytomas in Beijing Tiantan Hospital between July 2000 and July 2016. The main clinical manifestations of the two patients were headache. The supratentorial intraventricular liponeurocytoma appeared as isodense to slight hyperdense on CT scan and heterogeneous intensity on T1-weighted imaging (T1WI) and T2-weighted imaging (T2WI)...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28948289/benign-periarticular-bone-and-joint-lipomatous-lesions
#13
Si Wei Kheok, Keh Oon Ong
Benign periarticular, bone and joint lipomatous lesions are rare entities that are increasingly being identified using current imaging techniques. This pictorial review illustrates the wide range of imaging presentations of these lesions at various sites and their pathognomonic features. The main lesions reviewed include intraosseous lipoma, liposclerosing myxofibrous tumour, lipoma arborescens and intra-articular lipoma.
September 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28937376/meningioma-with-the-unique-coexistence-of-secretory-and-lipomatous-components-a-case-report-with-immunohistochemical-study
#14
Purwa R Patil, Bhushan M Warpe, Vijay H Juvekar, Vidya Manohar
Meningioma is the most common extra-axial neoplasm which accounts for 30% of all intracranial tumors with a female predilection. These tumors exhibit a broad spectrum of differentiation potency corresponding to different histological subtypes. Meningothelial cells can rarely show separate secretory or lipomatous (metaplastic) transformation. The coexistence of these two different histological subtypes in a single meningeal tumor is extremely rare with only two reported cases. We report an uncommon case of meningioma in a 40-year-old female showing histological admixture of both secretory and lipomatous (metaplastic) meningioma, which to our knowledge is only the third reported case in the world...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28937374/malignant-phyllodes-tumor-with-heterologous-differentiation-clinicopathological-spectrum-of-nine-cases-in-a-tertiary-care-institute-in-eastern-india
#15
Mamita Nayak, Susama Patra, Pritinanda Mishra, Nibedita Sahoo, Prakash Kumar Sasmal, Tushar Subhadarshan Mishra
Phyllodes tumors are uncommon fibroepithelial neoplasms of breast. Heterologous sarcomatous differentiation of malignant phyllodes tumor (MPT) is a rare phenomenon as shown in the literature. Herein we report a series of nine cases from a tertiary care centre in Eastern India. Patients demographic data and clinical details were obtained from the medical records. Histopathology and immunohistochemical studies were analysed and diagnosed accordingly. Out of 38 cases of PT, 13 were found to be MPT, of which 9 cases showed heterologous differentiation in the form of angiosarcoma, fibrosarcoma, undifferentiated sarcoma, extensive squamous differentiation and with lipomatous metaplasia...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28902468/fine-needle-aspiration-of-lipoblastoma-cytological-molecular-and-clinical-features
#16
Joana Ferreira, Gonçalo Esteves, Ricardo Fonseca, Carmo Martins, Saudade André, Maria Manuel Lemos
BACKGROUND: Lipoblastomas are rare, benign adipocytic tumors that present mostly during infancy. In about 70% of cases, these tumors carry abnormalities in chromosome 8, mainly leading to rearrangements of the PLAG1 gene. METHODS: We report a series of histologically proven lipoblastomas with previous fine-needle aspiration (FNA) cytology from 9 patients (n = 10 samples) and describe their clinical, cytological, and molecular features. RESULTS: Our cohort included 5 boys and 4 girls (median age, 2...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28877055/solitary-fibrous-tumors-of-the-head-and-neck-a-multi-institutional-clinicopathologic-study
#17
Steven C Smith, William E Gooding, Matthew Elkins, Rajiv M Patel, Paul W Harms, Andrew S McDaniel, Nallasivam Palanisamy, Cora Uram-Tuculescu, Bonnie B Balzer, David R Lucas, Raja R Seethala, Jonathan B McHugh
Solitary fibrous tumors (SFTs) of the head and neck are uncommon. Lesions previously diagnosed in the head and neck as hemangiopericytomas (HPCs), giant cell angiofibromas (GCAs), and orbital fibrous histiocytomas (OFHs) are now recognized as within the expanded spectrum of SFTs. To better understand the clinicopathologic profile of head and neck SFTs, we performed a multi-institutional study of 88 examples. There was no sex predilection (F:M ratio 1.2), and the median patient age was 52 years (range: 15 to above 89 y)...
December 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28877053/-atypical-pleomorphic-lipomatous-tumor-a-clinicopathologic-immunohistochemical-and-molecular-study-of-21-cases-emphasizing-its-relationship-to-atypical-spindle-cell-lipomatous-tumor-and-suggesting-a-morphologic-spectrum-atypical-spindle-cell-pleomorphic-lipomatous
#18
MULTICENTER STUDY
David Creytens, Thomas Mentzel, Liesbeth Ferdinande, Evelyne Lecoutere, Joost van Gorp, Lilit Atanesyan, Karel de Groot, Suvi Savola, Nadine Van Roy, Jo Van Dorpe, Uta Flucke
The classification of the until recently poorly explored group of atypical adipocytic neoplasms with spindle cell features, for which recently the term atypical spindle cell lipomatous tumor (ASLT) has been proposed, remains challenging. Recent studies have proposed ASLT as a unique entity with (in at least a significant subset of cases) a specific genetic background, namely deletions/losses of 13q14, including RB1 and its flanking genes RCBTB2, DLEU1, and ITM2B. Similar genetic aberrations have been reported in pleomorphic liposarcomas (PLSs)...
November 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28876176/gynecomastia-histological-appearance-in-different-age-groups
#19
Alba Fricke, Gabriele M Lehner, G Björn Stark, Vincenzo Penna
OBJECTIVE: Gynecomastia is a common finding in the male population which is mostly idiopathic. The aim of our study was to analyze the histological differences in young and old patient groups and its association with recurrence rates. METHODS: Three hundred and five gynecomastia patients (555 breasts) undergoing surgical treatment from 1997 to 2015 were divided into four groups: Group 1: 13-17 years, Group 2: 18-30 years, Group 3: 31-49 years and Group 4: 50-83 years...
September 6, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28858184/idiopathic-spinal-epidural-fat-accumulation-is-associated-with-hyperlipidemia
#20
Shinichi Ishihara, Nobuyuki Fujita, Mitsuru Yagi, Takashi Tsuji, Takehiro Michikawa, Yuji Nishiwaki, Yasuyuki Fukui, Keisuke Horiuchi, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
STUDY DESIGN: Single-center retrospective analysis of consecutively collected data. OBJECTIVES: To determine the clinical characteristics of idiopathic spinal epidural lipomatosis (SEL). SUMMARY OF BACKGROUND DATA: SEL is associated with the overt accumulation of nonencapsulated adipose tissue in the epidural space, leading to spinal cord or nerve root compression. The etiology of this condition is currently not completely understood. METHODS: Data of 166 male patients who underwent primary surgery for lumbar spinal canal stenosis (LSS) from May 2013 to February 2016 were retrospectively reviewed...
August 29, 2017: Spine
keyword
keyword
79799
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"