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https://www.readbyqxmd.com/read/28902468/fine-needle-aspiration-of-lipoblastoma-cytological-molecular-and-clinical-features
#1
Joana Ferreira, Gonçalo Esteves, Ricardo Fonseca, Carmo Martins, Saudade André, Maria Manuel Lemos
BACKGROUND: Lipoblastomas are rare, benign adipocytic tumors that present mostly during infancy. In about 70% of cases, these tumors carry abnormalities in chromosome 8, mainly leading to rearrangements of the PLAG1 gene. METHODS: We report a series of histologically proven lipoblastomas with previous fine-needle aspiration (FNA) cytology from 9 patients (n = 10 samples) and describe their clinical, cytological, and molecular features. RESULTS: Our cohort included 5 boys and 4 girls (median age, 2...
September 13, 2017: Cancer
https://www.readbyqxmd.com/read/28877055/solitary-fibrous-tumors-of-the-head-and-neck-a-multi-institutional-clinicopathologic-study
#2
Steven C Smith, William E Gooding, Matthew Elkins, Rajiv M Patel, Paul W Harms, Andrew S McDaniel, Nallasivam Palanisamy, Cora Uram-Tuculescu, Bonnie B Balzer, David R Lucas, Raja R Seethala, Jonathan B McHugh
Solitary fibrous tumors (SFTs) of the head and neck are uncommon. Lesions previously diagnosed in the head and neck as hemangiopericytomas (HPCs), giant cell angiofibromas (GCAs), and orbital fibrous histiocytomas (OFHs) are now recognized as within the expanded spectrum of SFTs. To better understand the clinicopathologic profile of head and neck SFTs, we performed a multi-institutional study of 88 examples. There was no sex predilection (F:M ratio 1.2), and the median patient age was 52 years (range: 15 to above 89 y)...
September 4, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28877053/-atypical-pleomorphic-lipomatous-tumor-a-clinicopathologic-immunohistochemical-and-molecular-study-of-21-cases-emphasizing-its-relationship-to-atypical-spindle-cell-lipomatous-tumor-and-suggesting-a-morphologic-spectrum-atypical-spindle-cell-pleomorphic-lipomatous
#3
David Creytens, Thomas Mentzel, Liesbeth Ferdinande, Evelyne Lecoutere, Joost van Gorp, Lilit Atanesyan, Karel de Groot, Suvi Savola, Nadine Van Roy, Jo Van Dorpe, Uta Flucke
The classification of the until recently poorly explored group of atypical adipocytic neoplasms with spindle cell features, for which recently the term atypical spindle cell lipomatous tumor (ASLT) has been proposed, remains challenging. Recent studies have proposed ASLT as a unique entity with (in at least a significant subset of cases) a specific genetic background, namely deletions/losses of 13q14, including RB1 and its flanking genes RCBTB2, DLEU1, and ITM2B. Similar genetic aberrations have been reported in pleomorphic liposarcomas (PLSs)...
September 4, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28876176/gynecomastia-histological-appearance-in-different-age-groups
#4
Alba Fricke, Gabriele M Lehner, G Björn Stark, Vincenzo Penna
OBJECTIVE: Gynecomastia is a common finding in the male population which is mostly idiopathic. The aim of our study was to analyze the histological differences in young and old patient groups and its association with recurrence rates. METHODS: Three hundred and five gynecomastia patients (555 breasts) undergoing surgical treatment from 1997 to 2015 were divided into four groups: Group 1: 13-17 years, Group 2: 18-30 years, Group 3: 31-49 years and Group 4: 50-83 years...
September 6, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28858184/idiopathic-spinal-epidural-fat-accumulation-is-associated-with-hyperlipidemia
#5
Shinichi Ishihara, Nobuyuki Fujita, Mitsuru Yagi, Takashi Tsuji, Takehiro Michikawa, Yuji Nishiwaki, Yasuyuki Fukui, Keisuke Horiuchi, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
STUDY DESIGN: Single-center retrospective analysis of consecutively collected data. OBJECTIVES: To determine the clinical characteristics of idiopathic spinal epidural lipomatosis (SEL). SUMMARY OF BACKGROUND DATA: SEL is associated with the overt accumulation of nonencapsulated adipose tissue in the epidural space, leading to spinal cord or nerve root compression. The etiology of this condition is currently not completely understood. METHODS: Data of 166 male patients who underwent primary surgery for lumbar spinal canal stenosis (LSS) from May 2013 to February 2016 were retrospectively reviewed...
August 29, 2017: Spine
https://www.readbyqxmd.com/read/28845581/primary-atypical-lipomatous-tumor-well-differentiated-liposarcoma-alt-wdl-of-the-breast
#6
Laurence M Briski, Deborah O Jeffries, Julie M Jorns
No abstract text is available yet for this article.
August 27, 2017: Breast Journal
https://www.readbyqxmd.com/read/28840101/radiofrequency-ablation-of-ventricular-tachycardia-originating-from-a-lipomatous-hamartoma-localized-in-the-right-ventricle-cavity
#7
Jin Xu, Yingmin Chen, Xiaoying Ying, Ben He
No abstract text is available yet for this article.
August 2017: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/28833506/a-case-of-congenital-lipomatous-overgrowth-vascular-malformations-epidermal-nevi-spinal-skeletal-anomalies-and-or-scoliosis-syndrome-with-lipoatrophy-as-an-important-clinical-manifestation
#8
Ariane Schreiber, Pierre-Olivier Grenier, Isabelle Auger
Congenital lipomatous overgrowth, vascular malformations, epidermal nevi, spinal/skeletal anomalies and/or scoliosis syndrome is a PIK3CA-related overgrowth spectrum presenting with congenital, asymmetric, disproportionate overgrowth associated with dysregulated adipose tissue, enlarged bony structures, and mixed primarily truncal vascular malformations. We present this case to raise awareness that very thin body habitus (lipoatrophy) contrasting with areas of overgrowth can be an important clinical feature of this syndrome and, if not recognized, can lead to unnecessary investigations...
August 22, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28822558/wilms-tumor-screening-in-diffuse-capillary-malformation-with-overgrowth-and-macrocephaly-capillary-malformation-a-retrospective-study
#9
Caitlin M Peterman, Sophie Vadeboncoeur, John B Mulliken, Steven J Fishman, Marilyn G Liang
BACKGROUND: CLOVES (congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies) syndrome is associated with regional bony and/or soft tissue overgrowth, capillary malformation, and an increased risk for Wilms tumor. OBJECTIVE: To evaluate the frequency of Wilms tumor in patients with 2 similar conditions: diffuse capillary malformation with overgrowth (DCMO) and macrocephaly-capillary malformation (M-CM). METHODS: Culling our Vascular Anomalies Center database, we retrospectively reviewed patients in whom DCMO and M-CM had been diagnosed and who were evaluated between 1998 and 2016 for possible development of Wilms tumor...
August 16, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28819497/-volvulus-of-the-small-intestine-caused-by-mesenteric-lipoma
#10
Papa Alassane Mbaye, Aime Lakh Faye, Aloise Sagna, Ndeye Aby Ndoye, Ndeye Fatou Seck, Oumar Ndour, Gabriel Ngom
We report the case of a 7-year old girl presenting with sub-occlusive syndrome associated with acute paroxysmal abdominal pain at the level of the upper abdomen, vomiting and no evacuation of faeces. Physical examination showed discomfort with palpation of the upper abdomen. Abdominal ultrasound showed poorly limited intraperitoneal tissue formation without vascular features on doppler, exercising a mass effect on the neighborhood structures; mesenteric vessels were in their normal position. This mass on CT scan scorresponded to a well limited lipomatous formation exercising a mass effect on the caecum associated with volvulus of the small intestine...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28818233/transcatheter-embolization-of-persistent-embryonic-veins-in%C3%A2-venous-malformation-syndromes
#11
Naiem Nassiri, Dustin Crystal, Lauren A Huntress, Susan Murphy
Persistent embryonic veins represent a major source of venous hypertension and morbidity in venous malformation syndromes, such as Klippel-Trénaunay syndrome and congenital lipomatous overgrowth, vascular malformations, epidermal nevus, and skeletal deformities syndrome. Surgical stripping and phlebectomy are the most commonly reported alternatives to compression therapy for refractory cases. These techniques, although effective in those patients who meet the necessary anatomic criteria, can be associated with bleeding, wound-related complications, and recurrence...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28807343/anisometric-cell-lipoma-insight-from-a-case-series-and-review-of-the-literature-on-adipocytic-neoplasms-in-survivors-of-retinoblastoma-suggest-a-role-for-rb1-loss-and-possible-relationship-to-fat-predominant-fat-only-spindle-cell-lipoma
#12
Abbas Agaimy
The term "anisometric cell lipoma" (ACL) has been proposed recently by Evans for a lipoma variant characterized by striking variation in size and shape of adipocytes but little or no cytological atypia. One patient with multiple ACL had a history of retinoblastoma. The current study analyzed six patients with ACL (4 males and two females aged 34 to 87years; median, 58); all seen in consultation. Five patients presented with solitary and one with multiple subcutaneous masses measuring 5 to 9cm (median, 7.5cm)...
August 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28781809/a-novel-protein-expression-signature-differentiates-benign-lipomas-from-well-differentiated-liposarcomas
#13
Quang Mather, Jonathon Priego, Kristi Ward, Verma Kundan, Dat Tran, Alok Dwivedi, Brad A Bryan
Benign lipomas and well-differentiated liposarcomas share many histological and molecular features. Due to their similarities, patients with these lipomatous tumors are misdiagnosed up to 40% of the time following radiological detection, up to 17% of the time following histological examination, and in as many as 15% of cases following fluorescent in situ hybridization for chromosomal anomalies. Incorrect classification of these two tumor types leads to increased costs to the patient and delayed accurate diagnoses...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28752151/intra-articular-lipoma-of-the-knee-joint-located-in-the-posterior-compartment-a-rare-location
#14
Mujdat Bankaoglu, Ozge Yapici Ugurlar, Meric Ugurlar, Mesut Mehmet Sonmez, Osman Tugrul Eren
This report presents the case of a 51-year-old woman with intermittent left knee pain, especially during full flexion of the knee, which had been ongoing for 1 year. Magnetic resonance imaging (MRI) showed mild effusion and round mass at the posterior compartment without synovial changes. Computerized tomography (CT) indicated mass had homogeneous low attenuation and density measurement of -99.4±62.3 Hounsfield units (HU), correlated with a lipomatous lesion.
2017: Northern Clinics of Istanbul
https://www.readbyqxmd.com/read/28719927/endoscopic-submucosal-dissection-of-a-huge-esophageal-atypical-lipomatous-tumor-well-differentiated-liposarcoma-with-a-4-year-recurrence-free-survival
#15
Ming-Yan Cai, Jia-Xin Xu, Ping-Hong Zhou
No abstract text is available yet for this article.
July 18, 2017: Endoscopy
https://www.readbyqxmd.com/read/28705709/a-novel-sclerosing-atypical-lipomatous-tumor-well-differentiated-liposarcoma-in-a-7-year-old-girl-report-of-a-case-with-molecular-confirmation
#16
Ran Peng, Huijiao Chen, Xuantao Yang, Xianliang Zhang, Zhang Zhang, Xin He, Hongying Zhang
Atypical lipomatous tumor/well-differentiated liposarcoma/dedifferentiated liposarcoma (ALT/WDL/DDL) is a common type of liposarcoma in late adulthood. However, pediatric ALT/WDL/DDL is extremely rare, and only 3 cases have been described in children younger than 10years of age. Notably, none of these cases harbored MDM2 gene amplification. Here, we reported a sclerosing ALT/WDL in a 7-year-old Chinese girl. Histologically, in most areas, the neoplastic cells were embedded within the collagenous background and typical lipogenic areas were inconspicuous throughout the sclerotic areas...
July 10, 2017: Human Pathology
https://www.readbyqxmd.com/read/28702400/sarcomatous-transformation-of-a-hemosiderotic-fibrohistiocytic-lipomatous-tumor-a-case-report
#17
Renata Margarida Etchebehere, Elia Cláudia Souza Almeida, Carlos David Teixeira Santos, Adilha Misson Rua Micheletti, Antônio Sebastião Leitão
Hemosiderotic fibrohistiocytic lipomatous tumors are rare neoplasms that were first described in 2000. Initially considered a benign lipotamous lesion of the soft tissues, nowadays they are considered to be a locally aggressive tumor. They occur mainly in the foot and ankle of women in their fifth and sixth decades, although they may be found in any place in the lower limbs and, more rarely, in other parts of the body. Histologically, hemosiderotic fibrohistiocytic lipomatous tumors consist of a mixture of mature adipose tissue, fusiform cell fascicles, macrophages that often contain cytoplasmic hemosiderin, mononuclear inflammatory infiltrate, and stroma that may be focally myxoid...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28698004/the-effect-of-radiotherapy-on-fat-content-and-fatty-acids-in-myxoid-liposarcomas-quantified-by-mri
#18
Mikael Skorpil, Henric Rydén, Johan Wejde, Elisabet Lidbrink, Otte Brosjö, Johan Berglund
BACKGROUND: Myxoid liposarcomas are highly radiosensitive. Consequently radiotherapy is often used pre-operatively to reduce tumor volume and lessen the post-operative deficit. In soft-tissue sarcomas therapy response is mainly evaluated using magnetic resonance imaging (MRI) and the fundamental criterion for a positive response is decreased tumor size. In myxoid liposarcomas an increased fat content is also known to occur as a response to radiotherapy. OBJECTIVE: To highlight the difficulties of MRI for therapy response evaluation in irradiated myxoid liposarcomas, by using MRI Dixon techniques enabling objective quantification of proton density fat fraction (%) and the number of double bonds (ndb; unsaturation degree) of fatty acids...
July 8, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28685800/intraosseous-hibernoma-a-case-report-and-review-of-the-literature
#19
Manel Yahia, B Laabidi, Issam M'sakni, Fethi Bougrine, Ammar Bouziani
Intraosseous hibernoma is a rare benign bone tumor, with only 4 cases reported in English literature. CASE REPORT: In this report, we describe a 42-year-old man with  no past medical history and right chest pain. Imaging studies showed an osteolytic lesion with fat attenuation lesion in the right fourth rib. The lesion was completely resected and microscopic study showed mildly thickened bone trabeculae and multivacuolated brown fat cells replacing the normal white fat and hematopoietic elements...
October 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28680732/a-case-report-and-review-of-thoracic-spinal-angiolipoma
#20
Yusif Mohammed, Shahed Elhamdani, Mobeen Farooq, Rida Mazagri
BACKGROUND: While it is a rare entity, spinal angiolipomas are well-defined benign tumors that have been described sporadically in the literature starting from the late 1800s. Composed of mature lipomatous and angiomatous elements, these tumors manifest neurological symptoms due to progressive spinal cord or root compression. We present a case of a thoracic spinal angiolipoma and review the relevant literature. CASE DESCRIPTION: A 68-year-old male with ongoing bilateral lower extremity weakness was found on enhanced magnetic resonance imaging to have an extradural mass in the thoracic spine causing cord compression...
2017: Surgical Neurology International
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