keyword
MENU ▼
Read by QxMD icon Read
search

Lipomatic

keyword
https://www.readbyqxmd.com/read/28328134/somatic-pik3ca-mutations-in-seven-patients-with-pik3ca-related-overgrowth-spectrum
#1
Kit San Yeung, Janice Jing Kun Ip, Chin Pang Chow, Evelyn Yue Ling Kuong, Paul Kwong-Hang Tam, Godfrey Chi-Fung Chan, Brian Hon-Yin Chung
Somatic mutations in PIK3CA cause many overgrowth syndromes that have been recently coined the "PIK3CA-Related Overgrowth Spectrum." Here, we present seven molecularly confirmed patients with PIK3CA-Related Overgrowth Spectrum, including patients with Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi, Scoliosis/Skeletal and Spinal syndrome, Klippel-Trenaunay syndrome, lymphatic malformation and two with atypical phenotypes that cannot be classified into existing disease categories. The literature on PIK3CA-Related Overgrowth Spectrum, suggests that PIK3CA c...
April 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28291056/perspectives-on-low-grade-sarcomas-the-extraordinary-contributions-of-sharon-w-weiss-md
#2
Hope Hastings, John R Goldblum
Soft-tissue pathology encompasses a wide spectrum of neoplasms that represent some of the most challenging and problematic tumors in surgical pathology. Owing to the intensive work of dedicated pathologists, this once esoteric field has become increasingly well defined. In this review, Dr Sharon Weiss' monumental contributions to low-grade sarcomas, including low-grade fibromyxoid sarcoma/so-called hyalinizing spindle cell tumor, atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma, epithelioid hemangioendothelioma, and dermatofibrosarcoma protuberans with fibrosarcomatous transformation will be discussed...
March 13, 2017: Advances in Anatomic Pathology
https://www.readbyqxmd.com/read/28286687/lipomatous-extensively-vacuolated-ependymoma-with-signet-ring-cell-like-appearance-analysis-of-a-case-with-extensive-literature-review
#3
Miguel Fdo Salazar, Martha Lilia Tena-Suck, Alma Ortiz-Plata, Citlaltepetl Salinas-Lara, Daniel Rembao-Bojórquez
"Lipomatous" and "extensively vacuolated" are descriptive captions that have been used to portray a curious subset of ependymomas distinctively bearing cells with a large vacuole pushing the nucleus to the periphery and, thus, simulating a signet-ring cell appearance. Here, we would like to report the first ependymoma of this kind in a Latin American institution. A 16-year-old boy experienced cephalea during three months. Magnetic resonance imaging scans showed a left paraventricular tumour which corresponded to anaplastic ependymoma...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28280898/long-term-follow-up-of-recurrence-and-patient-satisfaction-after-surgical-treatment-of-gynecomastia
#4
A Fricke, G M Lehner, G B Stark, V Penna
BACKGROUND: "Gynecomastia" is an enlargement of the male breast. Our study aims to assess patient satisfaction as well as evaluate differences in recurrence rates in lipomatous and glandular gynecomastia 10-19 years postoperatively. METHODS: Forty-one gynecomastia patients undergoing surgical treatment from 1997 to 2005 were invited for a follow-up examination 10-19 years postoperatively. Of these, 16 patients presented for a clinical examination. Patient satisfaction was measured with a validated questionnaire [consultation satisfaction questionnaire (CSQ)-9]...
March 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28247108/lateral-lipomyelomeningocele-of-the-hemicord-with-split-cord-malformation-type-i-revealed-by-3d-heavily-t2-weighted-mr-imaging
#5
Nobuya Murakami, Takato Morioka, Masako Ichiyama, Ryoko Nakamura, Nobuko Kawamura
BACKGROUND: Lipomyelomeningocele (LMMC) is defined by a low-lying tethered spinal cord protruding posteriorly from the spinal canal and terminating in a lipomatous mass in the subcutaneous meningeal sac. The coexistence of LMMC with split cord malformation (SCM) is rare. CLINICAL PRESENTATION: We report on a patient with laterally protruded LMMC arising from the hemicord of SCM type I. Direct coronal and axial views (instead of sagittal views) of 3D heavily T2-weighted MR imaging (3D-hT2WI) clearly demonstrated the topographical relationship between both of the hemicords, the bony septum, and nerve roots in the right subcutaneous meningeal sac...
February 28, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28245542/-recurrence-of-well-differentiated-intrascrotal-liposarcoma-in-retroperitoneum-five-years-after-resection-a-case-report
#6
Mitsuhiro Yoshinaga, Yosuke Sekii, Shigeaki Nakazawa, Masahiro Nakagawa, Hidefumi Kishikawa, Kenji Nishimura
A 68-year-old man underwent an inguinal orchiectomy for a right testicular tumor and the pathological diagnosis was atypical lipomatous tumor. Nine years later, a resection procedure was performed for local recurrence. Five years after that second surgery, abdominal computed tomography (CT) findings revealed a low density mass 40 mm in size on the back side of the right kidney and enlarged fat in the retroperitoneal space. We performed a laparoscopic tumor resection under a diagnosis of lipoma or liposarcoma recurrence, and the pathological diagnosis was well differentiated liposarcoma...
January 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28236115/the-clinicopathological-features-of-liponeurocytoma
#7
Li Xu, Jiang Du, Junmei Wang, Jingyi Fang, Zhaoxia Liu, Yanjiao He, Guilin Li
To discuss the clinicopathological features of liponeurocytoma, we retrospectively reviewed three liponeurocytoma cases and compared their immunophenotypes and genotypes with those of similar tumors. Furthermore, we reviewed the literature and compared the similarities and differences between cerebellar and intraventricular liponeurocytomas. Two cerebellar and one intraventricular liponeurocytomas were included in the present study. The liponeurocytomas comprised small tumor cells and lipomatous cells. The tumor cells expressed SYN, MAP-2, and NeuN...
January 2017: Brain Tumor Pathology
https://www.readbyqxmd.com/read/28212053/transthoracic-echocardiography-pitfalls-and-limitations-as-delineated-at-cardiac-ct-and-mr-imaging
#8
Sachin B Malik, Natalie Chen, Rex A Parker, Joe Y Hsu
Transthoracic echocardiography ( TTE transthoracic echocardiography ) is a critical tool in the field of clinical cardiology. It often serves as one of the first-line imaging modalities in the evaluation of cardiac disease owing to its low cost, portability, widespread availability, lack of ionizing radiation, and ability to evaluate both anatomy and function of the heart. Consequently, a large majority of patients undergoing a cardiac computed tomography (CT) or magnetic resonance (MR) imaging examination will have a TTE transthoracic echocardiography available for review...
March 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28155209/do-mesenchymal-stem-cells-derived-from-atypical-lipomatous-tumors-have-greater-differentiation-potency-than-cells-from-normal-adipose-tissues
#9
Hiroyuki Inatani, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Akihiko Takeuchi, Shinji Miwa, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Satoshi Yamada, Kiyofumi Asai, Takanobu Otsuka, Hiroyuki Tsuchiya
BACKGROUND: The p53 protein in mesenchymal stem cells (MSCs) regulates differentiation to osteogenic or adipogenic lineage. Because p53 function is depressed in most malignancies, if MSCs in malignancy also have p53 hypofunction, differentiation therapy to osteogenic or adipogenic lineage may be an effective treatment. We therefore wished to begin to explore this idea by evaluating atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) cells, because murine double minute 2 (MDM2) gene amplification, which leads to p53 hypofunction, is found in almost all ALT/WDLs...
February 2, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28149104/lipomatous-meningioma-a-rare-subtype-of-benign-metaplastic-meningiomas
#10
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Osman Tanrıverdi, Sevilay Akalp Özmen
Lipomatous meningiomas are extremely rare subtypes of benign meningiomas and are classified as metaplastic meningioma in the World Health Organization classification. We present a 77-year-old man presented with the history of a gradually intensifying headache for the last 3 months. A right frontoparietal mass was detected on his cranial magnetic resonance imaging. The patient was operated on via a right frontoparietal craniotomy, and histopathological diagnosis was lipomatous meningioma. Distinctive characteristics of lipomatous meningiomas were discussed with special emphasis to importance of immunohistochemical examinations, particularly for its differentiation from the tumors showing similar histology though having more aggressive character...
January 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28143811/lipomatous-tumours-in-adrenal-gland-who-updates-and-clinical-implications
#11
Alfred Lam
Adrenal lipomatous tumour is a group of adrenal tumours with a significant component of adipose tissue. According to the current World Health Organization (WHO) classification of tumours of endocrine organs, adrenal myelolipoma is the only entity amongst the group of tumours being described. In the literature, other more recently documented adrenal lipomatous tumours included 24 lipomas, 32 teratomas and 16 angiomyolipomas. Rare fatty tumours of the adrenal gland comprised liposarcoma, hibernoma, adrenocortical tumours with fat component and rare adrenal tumours with fat component...
January 31, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28139026/spindle-cell-lipoma-with-prominent-verocay-bodies-a-potential-diagnostic-pitfall
#12
Mark McInturff, Bradley Graham
Spindle cell lipoma is a benign lipomatous neoplasm that tends to occur near the upper back, or posterior neck of adult males. The tumor has characteristic histology with variably cellular spindle cell areas surrounding mature adipose tissue. With the classic clinical history diagnosis is usually straight forward. However, the location and or histology may not always be so classic, in which case immunohistochemical stains may be helpful. We present a case of spindle cell lipoma with prominent Verocay bodies and a review of the literature to draw attention to possible diagnostic pitfalls...
January 31, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28123735/lipomatous-angiomyofibroblastoma-of-the-vulva-a-case-report-and-review-of-the-literature
#13
Susumu Matsukuma, Ayano Koga, Ryohei Suematsu, Hiroaki Takeo, Kimiya Sato
Lipomatous angiomyofibroblastoma is extremely rare, with only 16 cases reported to date. We herein describe an additional case arising in the left vulvar region of a 49-year-old woman. The resected 5.3-cm yellowish tumor predominantly consisted of fat cells (85% of the tumor), together with medium- and small-sized vessels, multifocal fibrotic areas and pseudoangiomatous spaces. Spindle, rounded, and/or epithelioid tumor cells proliferated in a nest and/or cord-like pattern, or singly within perivascular fibrous tissues and between fat cells...
January 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28116271/intraosseous-lipoma-of-the-proximal-radius-with-extra-osseous-extension-leading-to-posterior-interosseous-nerve-compression-hrus-diagnosis
#14
S Narayan, V Verma Ahluwalia, P Singh Saharan, A Kumar Gupta
INTRODUCTION: Benign musculoskeletal lipomatous lesions are common in both soft tissue and bone. Imaging features of benign lipomatous lesions are often pathognomonic. Ultrasound (US) has been used to examine both soft tissue and bone tumors, allowing targeted CT or MRI examination of the region of interest. CASE REPORT: A 46-year-old female presented with a four year history of palpable mass lesion just below the lateral aspect of right elbow with clinical evidence of posterior interosseous nerve compression...
July 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28105611/huge-mediastinal-liposarcoma-resected-by-clamshell-thoracotomy-a-case-report
#15
Michihito Toda, Nobuhiro Izumi, Takuma Tsukioka, Hiroaki Komatsu, Satoshi Okada, Kantaro Hara, Ryuichi Ito, Toshihiko Shibata, Noritoshi Nishiyama
BACKGROUND: Liposarcoma is the single most common soft tissue sarcoma. Because mediastinal liposarcomas often grow rapidly and frequently recur locally despite adjuvant chemotherapy and radiotherapy, they require complete excision. Therefore, the feasibility of achieving complete surgical excision must be carefully considered. We here report a case of a huge mediastinal liposarcoma resected via clamshell thoracotomy. CASE PRESENTATION: A 64-year-old man presented with dyspnea on effort...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28070930/pituitary-adenoma-with-adipose-tissue-a-new-metaplastic-variant
#16
Chiara Caporalini, Anna Maria Buccoliero, Luigi Pansini, Selene Moscardi, Luca Novelli, Gianna Baroni, Lorenzo Bordi, Franco Ammannati, Gian Luigi Taddei
Pituitary adenomas are benign tumors representing approximately 15-20% of intracranial neoplasms. There have been few reports of metaplastic osseous transformation and about 60 cases of neuronal metaplasia in pituitary adenoma but adipose metaplasia has not been previously described in the English literature. Here we report a case of pituitary adenoma with metaplastic adipose tissue in a 58-year-old male patient. Histologically this case fulfilled the criteria of a non-functioning pituitary adenoma, and moreover a central area of adipose tissue, made by mature adipocytes, and many tumor cells, containing fat droplet were evident...
January 9, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28050116/lipomatous-pseudohypertrophy-of-pancreas-with-coexisting-chronic-calcific-pancreatitis-leading-to-malabsorption-due-to-exocrine-pancreatic-insufficiency
#17
Devendra Nema, Sumeet Arora, Ashutosh Mishra
No abstract text is available yet for this article.
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28045832/low-fat-plexiform-spindle-cell-lipoma-with-prominent-myxoid-stroma-an-unusual-oral-presentation-and-immunohistochemical-analysis
#18
Jessica Luana Dos Santos, Eduardo Akira Ocamoto, Luciana Yamamoto Almeida, Lucas Ribeiro Teixeira, Alfredo Ribeiro-Silva, Jorge Esquiche León
Spindle cell lipoma (SCL) and pleomorphic lipoma constitute a spectrum of lipomatous lesions with distinctive clinicopathological features. Multiple variants of SCL have been reported including fibrous, plexiform, vascular, pseudoangiomatous, low-fat/fat-free, and myxoid changes. This paper describes an unusual patient with a 1-cm submucosal nodular lesion excised from the buccal mucosa of a 55-year-old woman with classic histopathological and immunohistochemical features of "low-fat" plexiform SCL with prominent myxoid stroma, which initially suggested a soft-tissue myxomatous lesion other than SCL...
March 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28032156/complex-truncal-masses-in-the-setting-of-cloves-syndrome-aesthetic-and-functional-implications
#19
Jason M Weissler, Valeriy Shubinets, Martin J Carney, David W Low
BACKGROUND: Congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal abnormalities (CLOVES) is a complex overgrowth syndrome with dramatic aesthetic and functional implications. The truncal masses characteristic of CLOVES syndrome are described as vascular malformations or lipomatous lesions with variable vascular components. Herein, we describe our single-institution experience with surgical excision of CLOVES-related truncal masses and discuss future directions in treatment of these complex anomalies...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27990391/encephalocraniocutaneous-lipomatosis-haberland-syndrome-a-rare-case-report
#20
Ashish Jagati, Bela J Shah, Rima Joshi, Trusha Gajjar
Haberland syndrome or Fishman syndrome also known as encephalocraniocutaneous lipomatosis (ECCL) is a rare, congenital neurocutaneous disorder. It is characterized by unilateral involvement of skin, eyes and central nervous system. We report the case of a 28-year-old woman who presented with soft lipomatous swelling over right temporal area with nonscarring alopecia of part of frontal and parietal region. The patient had a history of seizures and ipsilateral scleral dermoid. Computed tomography scan findings were suggestive of lipomas and calcification of falx...
November 2016: Indian Dermatology Online Journal
keyword
keyword
79799
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"