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https://www.readbyqxmd.com/read/28324945/a-comparative-study-of-pseudorandom-sequences-used-in-a-c-vep-based-bci-for-online-wheelchair-control
#1
Jonas Isaksen, Ali Mohebbi, Sadasivan Puthusserypady
In this study, a c-VEP based BCI system was developed to run on three distinctive pseudorandom sequences, namely the m-code, the Gold-code, and the Barker-code. The Visual Evoked Potentials (VEPs) were provoked using these codes. In the online session, subjects controlled a LEGO(®) Mindstorms(®) robot around a fixed track. Choosing the optimal code proved a significant increase in accuracy (p<;0.00001) over the average performance. No single code proved significantly more accurate than the others (p=0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324509/human-telomeric-g-quadruplex-structures-and-g-quadruplex-interactive-compounds
#2
Clement Lin, Danzhou Yang
G-quadruplexes are noncanonical secondary structures formed in DNA sequences containing consecutive runs of guanines. It has been shown that the 3' G-rich single-stranded overhangs of human telomeres can form G-quadruplex structures, and the human telomeric DNA G-quadruplexes are considered attractive targets for anticancer drugs. G-quadruplex-interactive compounds have been shown to inhibit telomerase access as well as telomere capping. Nuclear magnetic resonance (NMR) spectroscopy is a powerful method in determining the G-quadruplex structures under physiologically relevant conditions...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28324174/combining-climatic-and-soil-properties-better-predicts-covers-of-brazilian-biomes
#3
Daniel M Arruda, Elpídio I Fernandes-Filho, Ricardo R C Solar, Carlos E G R Schaefer
Several techniques have been used to model the area covered by biomes or species. However, most models allow little freedom of choice of response variables and are conditioned to the use of climate predictors. This major restriction of the models has generated distributions of low accuracy or inconsistent with the actual cover. Our objective was to characterize the environmental space of the most representative biomes of Brazil and predict their cover, using climate and soil-related predictors. As sample units, we used 500 cells of 100 km(2) for ten biomes, derived from the official vegetation map of Brazil (IBGE 2004)...
April 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28323893/effect-of-supervised-exercise-training-during-pregnancy-on-neonatal-and-maternal-outcomes-among-overweight-and-obese-women-secondary-analyses-of-the-etip-trial-a-randomised-controlled-trial
#4
Kirsti Krohn Garnæs, Siri Ann Nyrnes, Kjell Åsmund Salvesen, Øyvind Salvesen, Siv Mørkved, Trine Moholdt
BACKGROUND: Maternal obesity associates with complications during pregnancy and childbirth. Our aim was to investigate if exercise during pregnancy in overweight/obese women could influence birth weight or other neonatal and maternal outcomes at delivery. MATERIAL AND METHODS: This is a secondary analysis of a randomised controlled trial of exercise training in pregnancy for women with body mass index (BMI) ≥ 28 kg/m2. Ninety-one women (31.3 ± 4.3 years, BMI 34...
2017: PloS One
https://www.readbyqxmd.com/read/28323537/impact-of-demographic-variables-on-women-s-economic-empowerment-an-ordered-probit-model
#5
Syeda Azra Batool, Hafiz Khalil Ahmed, Shazia Noureen Qureshi
The present study aimed to empirically examine the demographic variables that determine women's economic empowerment. A sample of 500 married women between 21 and 49 years old (Mage = 35.49, SD = 7.66) was conveniently selected from district Multan (Pakistan). Control over economic resources was used as a proxy for women's economic empowerment. Ordered probit regression was run to assess the demographic determinants (i.e., age, education, paid job, income, and property) of economic empowerment of the least empowered, moderately empowered, and highly empowered women...
March 21, 2017: Journal of Women & Aging
https://www.readbyqxmd.com/read/28323464/physical-mental-and-financial-impacts-from-drought-in-two-california-counties-2015
#6
Tracy Barreau, David Conway, Karen Haught, Rebecca Jackson, Richard Kreutzer, Andrew Lockman, Sharon Minnick, Rachel Roisman, David Rozell, Svetlana Smorodinsky, Dana Tafoya, Jason A Wilken
OBJECTIVES: To evaluate health impacts of drought during the most severe drought in California's recorded history with a rapid assessment method. METHODS: We conducted Community Assessments for Public Health Emergency Response during October through November 2015 in Tulare County and Mariposa County to evaluate household water access, acute stressors, exacerbations of chronic diseases and behavioral health issues, and financial impacts. We evaluated pairwise associations by logistic regression with pooled data...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28319659/improving-computational-predictions-of-single-stranded-rna-tetramers-with-revised-%C3%AE-%C3%AE-torsional-parameters-for-the-amber-force-field
#7
David J Wales, Ilyas Yildirim
With current advancements in RNA based therapeutics, it is becoming crucial to utilize theoretical and computational methods to describe properly the physical properties of RNA molecules. NMR and X-ray crystallography are two powerful techniques for investigating structural properties. However, if the RNA molecules are complex or dynamic, these methods might not be adequate. For computational approaches, the quality of the force field will determine accuracy of our predictions. In this contribution, we revise the α/γ torsional parameters of RNA for amber force field using a model system representing an RNA dimer backbone...
March 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28319519/process-improvement-initiative-for-the-perioperative-management-of-patients-with-a-cardiovascular-implantable-electronic-device
#8
Margaret K Menzel Ellis, Miriam M Treggiari, Jamie M Robertson, Marc A Rozner, Peter F Graven, Michael F Aziz, Matthias J Merkel, Edward A Kahl, Norman A Cohen, Eric C Stecker, Peter M Schulman
BACKGROUND: Economic, personnel, and procedural challenges often complicate and interfere with efficient and safe perioperative care of patients with cardiovascular implantable electronic devices (CIEDs). In the context of a process improvement initiative, we created and implemented a comprehensive anesthesiologist-run perioperative CIED service to respond to all routine requests for perioperative CIED consultations at a large academic medical center. This study was designed to determine whether this new care model was associated with improved operating room efficiency, reduced institutional cost, and adequate patient safety...
March 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28319150/high-throughput-transformation-of-saccharomyces-cerevisiae-using-liquid-handling-robots
#9
Guangbo Liu, Clayton Lanham, J Ross Buchan, Matthew E Kaplan
Saccharomyces cerevisiae (budding yeast) is a powerful eukaryotic model organism ideally suited to high-throughput genetic analyses, which time and again has yielded insights that further our understanding of cell biology processes conserved in humans. Lithium Acetate (LiAc) transformation of yeast with DNA for the purposes of exogenous protein expression (e.g., plasmids) or genome mutation (e.g., gene mutation, deletion, epitope tagging) is a useful and long established method. However, a reliable and optimized high throughput transformation protocol that runs almost no risk of human error has not been described in the literature...
2017: PloS One
https://www.readbyqxmd.com/read/28319019/recycling-of-metals-from-pretreated-waste-printed-circuit-boards-effectively-in-stirred-tank-reactor-by-a-moderately-thermophilic-culture
#10
Ming-Chen Xia, Ya-Ping Wang, Tang-Jian Peng, Li Shen, Run-Lan Yu, Yuan-Dong Liu, Miao Chen, Jiao-Kun Li, Xue-Ling Wu, Wei-Min Zeng
To seek a feasible technique for processing waste printed circuit boards (PCBs), pretreatment of PCBs by table separation and further bioleached by moderate thermophiles in a stirred tank reactor were investigated. The shaking table separation, conducted after grinding and sieving of PCBs, produced two fractions: metal-rich parts (RPCBs), which is more suitable for pyrometallurgy process than untreated PCBs, and metal-poor parts (PPCBs) with only 8.83% metals was then bioleached by a mixed culture of moderate thermophiles effectively...
March 15, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28318931/recent-bremsstrahlung-based-assays-of-210-pb-in-lead-and-comments-on-current-availability-of-low-background-lead-in-north-america
#11
Martin E Keillor, C E Aalseth, I J Arnquist, T A Eggemeyer, E S Fuller, B D Glasgow, E W Hoppe, S M Morley, A W Myers, J L Orrell, C T Overman, A Seifert, S M Shaff, K S Thommasson
Low-background lead for radiation measurement shielding is often assayed for (210)Pb to ensure acceptable backgrounds. Samples of lead assayed with a germanium spectrometer calibrated for bremsstrahlung-based assay of (210)Pb provide a view into the (210)Pb content of commercial lead in the U.S. (other than stockpiled Doe Run lead). Results suggest that the loss of lead smelting in the U.S. has eliminated the traditional supply of "low background" lead (~30Bqkg(-1)), and indicate current commercial supplies contain roughly an order of magnitude higher (210)Pb levels...
March 3, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28318860/a-prospective-randomized-trial-comparing-liposomal-bupivacaine-vs-fascia-iliaca-compartment-block-for-postoperative-pain-control-in-total-hip-arthroplasty
#12
Molly A McGraw-Tatum, Michael T Groover, Nicole E George, John S Urse, Victor Heh
BACKGROUND: Increasing demand for total hip arthroplasty (THA) in a climate of increasing focus on clinical outcomes, patient satisfaction, and cost has created a need for better acute postoperative pain control for patients. An ideal pain control method would have few side effects, decreased opioid consumption, improved pain control, early ambulation, and decreased hospital length of stay (LOS). METHODS: We performed a prospective randomized, controlled study involving 79 patients undergoing elective THA between June 2015 and February 2016...
February 16, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28318758/-patient-safety-culture-in-directors-and-managers-of-a-health-service
#13
Teresa Giménez-Júlvez, Ignacio Hernández-García, Carlos Aibar-Remón, Isabel Gutiérrez-Cía, Mercedes Febrel-Bordejé
OBJECTIVE: To assess patient safety culture in directors/managers. METHODS: Cross-sectional descriptive study carried out from February to June 2011 among the executive/managing staff of the Aragón Health Service through semi-structured interviews. RESULTS: A total of 12 interviews were carried out. All the respondents admitted that there were many patient safety problems and agreed that patient safety was a priority from a theoretical rather than practical perspective...
March 16, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28318224/defects-mediated-corrosion-in-graphene-coating-layer
#14
Jincheng Lei, Yaowu Hu, Zishun Liu, Gary J Cheng, Kejie Zhao
Mixed results were reported on the anticorrosion of graphene coated metal surfaces - while graphene serves as an effective short-term barrier against corrosion and oxidation due to its low permeability to gases, the galvanic cell between graphene and metal substrate facilitates extensive corrosion in the long run. Defects in the graphene layer provide pathways for the permeation of oxidizing species. We study the role of defects in graphene in the anticorrosion using first-principles theoretical modeling. Experiments in the highly reactive environment indicate that the oxidized products primarily distribute along the grain boundaries of graphene...
March 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28318135/effect-of-coronary-dominance-on-2-year-outcomes-after-percutaneous-coronary-intervention-in-patients-with-acute-coronary-syndrome
#15
Chen He, Yuan-Liang Ma, Chuang-Shi Wang, Ying Song, Xiao-Fang Tang, Xue-Yan Zhao, Run-Lin Gao, Yue-Jin Yang, Bo Xu, Jin-Qing Yuan
OBJECTIVES: This retrospective, single-center, observational analysis from prospectively collected database evaluated whether left dominance affected the long-term outcomes of acute coronary syndrome patients undergoing percutaneous coronary intervention, and whether the effect was independent of SYNTAX score. BACKGROUND: Left dominance is believed to be associated with worse prognoses. The anatomical SYNTAX score is a scoring system based on the complexity and severity of coronary lesions and is thought to be a prognostic tool to predict short- and long-term outcomes...
March 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28317966/ethylene-polymerization-catalyzed-by-bridging-ni-zn-heterobimetallics
#16
Hsin-Chun Chiu, Arijit Koley, Peter L Dunn, Ryan J Hue, Ian A Tonks
The effect of proximal Zn halides on Ni-catalyzed ethylene polymerization is reported in this work. A series of (NON)NiLX (NON = 2,6-bis-((2,6-diisopropylphenyl)imino)methyl phenoxide; LX = methallyl or L = py, X = tolyl, 2-4) ethylene polymerization precatalysts have been synthesized, as well as a heterobimetallic Ni/Zn complex, (NON)Ni(C4H7)ZnBr2 (5). Each precatalyst could be activated (or promoted) by ZnX2 (X = Cl, Br, Et) to polymerize ethylene. In situ recruitment of ZnX2 by the free imine binding pocket of the NON complexes results in the generation of heterobimetallic active species that produce lower Mn polyethylene than monometallic controls...
March 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28317702/rapid-determination-of-flavonoids-and-phenolic-acids-in-grape-juices-and-wines-by-rp-hplc-dad-method-validation-and-characterization-of-commercial-products-of-the-new-brazilian-varieties-of-grape
#17
Carla Valéria da Silva Padilha, Gabriela Aquino Miskinis, Marcelo Eduardo Alves Olinda de Souza, Giuliano Elias Pereira, Débora de Oliveira, Marilde Terezinha Bordignon-Luiz, Marcos Dos Santos Lima
A method for rapid determination of phenolic compounds by reversed-phase high-performance liquid chromatography (RP-HPLC), using a new column of faster resolution was validated and used to characterize commercial products produced with new grape Brazilian varieties of Northeast of Brazil. The in vitro antioxidant activity was also measured. The method showed linearity (R>0.9995), good precision (CV%<2.78), recovery (91.8-105.1%) and limits of detection (0.04-0.85mgL(-1)) and quantification (0.04-1.41mgL(-1)) according to other methods previously published with the difference of a run time of only 25min...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317144/uhplc-ms-ms-method-for-the-determination-of-omarigliptin-in-rat-plasma-and-its-application-to-a-pharmacokinetic-study-in-rats
#18
Meng-Fang Li, Xiao-Xia Hu, Ai-Qun Ma
Omarigliptin is a novel long-acting DPP-4 inhibitor used for the treatment of T2DM. In this work, a sensitive and selective UHPLC-MS/MS method was developed and validated for determination of omarigliptin in rat plasma. Sample preparation was performed by protein precipitation with acetonitrile. Chromatographic separation of analytes was achieved on a RRHD Eclipse Plus C18 column (2.1 × 50 mm, 1.8 µ), using gradient mobile phase (0.1% formic acid-acetonitrile) at a flow rate of 0.4 mL/min. Detection was performed in multiple reaction monitoring mode, with target fragment ions m/z 399...
March 19, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28316207/-a-preliminary-discussion-on-the-contents-and-value-of-shi-er-mai-twelve-channels-and-bie-mai-allo-channels-the-medical-bamboo-slips-unearthed-from-han-tomb-in-laoguanshan-of-chengdu
#19
Y L Ren, F R Liang, J M Li, Z H Chen, Y T Wang, M X Yang, Z Z He
The 52 medical bamboo slips entitled Si er ma (Twelve Channels) and Bie mai (Allo-channels) , unearthed from Han tomb in Laoguanshan, are the exclusive medical books concerning channels. Shi er mai is the first work bearing the term " heart dominating channel" , and the running pathways and manifestations of 12 channels. This book could be the major original sources of the 12-channel theories described in the Chapter of Jing mai (Channels) of Ling shu (Miraculous Pivot) . While Bie mai suggests the coexistence of the multi-channel systems at the time when the book was compiled and, together with the 12 "channel" , and 3 "branched collaterals" , these 2 books represent the original condition before the establishment of the mode of channel circulation in Ling shu, and is significant to explore the nature and origin of channel...
January 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28315976/tfoi-produced-by-tepidimonas-fonticaldi-pl17-a-moderate-thermophilic-bacterium-is-an-isoschizomer-of-msei
#20
Ravinder Kumar, Anil Kumar Pinnaka, Beena Krishnan
A moderately thermophilic Gram-negative bacterium isolated from the Polok hot spring, Sikkim, India, was identified as a strain (PL17) of Tepidimonas fonticaldi by 16S rDNA sequencing. T. fonticaldi PL17 produces a Type IIP restriction endonuclease; named TfoI. Restriction mapping, run-off sequencing of TfoI-digests of dsDNA fragments, and end compatibility of TfoI with NdeI confirmed that the enzyme recognizes and cleaves the sequence 5'-T^TAA-3', and is thus an isoschizomer of MseI. The TfoI restriction-modification genes in the T...
March 18, 2017: Extremophiles: Life Under Extreme Conditions
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