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https://www.readbyqxmd.com/read/28636369/dynamics-of-charged-species-in-ionic-neutral-block-copolymer-and-surfactant-complexes
#1
Jose M Borreguero, Philip A Pincus, Bobby G Sumpter, Monojoy Goswami
Structure-property relationships of ionic block copolymer (BCP) surfactant complexes are critical towards the progress of favorable engineering design of efficient charge transport materials. In this article, molecular dynamics simulations are used to understand the dynamics of charge-neutral BCP and surfactant complexes. The dynamics are examined for two different systems, charged-neutral double hydrophilic and hydrophobic-hydrophilic block copolymers with oppositely charged surfactant moieties. The dynamics of the surfactant head, tails and charges are studied for five different BCP volume fractions...
June 21, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28634923/osteoblastoma-of-the-elbow-analysis-of-13-patients-and-literature-review
#2
Andrea Angelini, Andrès Felipe Varela-Osorio, Giulia Trovarelli, Antonio Berizzi, Gabriele Zanotti, Pietro Ruggieri
PURPOSE: To analyze the clinical and radiographic characteristics, treatment, and outcome of patients with elbow osteoblastoma. PATIENTS AND METHODS: We present 13 patients (7 males and 6 females; mean age, 28 years) diagnosed and treated for an elbow osteoblastoma from 1975 to 2012. Mean follow-up was 29 months (range 12-60 months). Clinical presentation, imaging, surgical treatment, complications, range of elbow motion, and functional outcome were evaluated...
June 20, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28603568/current-concepts-in-radial-club-hand
#3
Takehiko Takagi, Atsuhito Seki, Shinichiro Takayama, Masahiko Watanabe
Radial club hand is a complex congenital abnormality of the radial or pre-axial border of the upper extremity. It has a wide range of phenotypes from hypoplasia of the thumb to complete absence of the radius and the first ray. Centralization with tendon transfer is a popular method for maintaining the correct position of radial club hand. On the other hand, various corrections were devised, e.g. radialization after distraction to emphasize the fact that the head of the ulna is positioned under the radial carpal bones and is no longer placed in a slot in the center of the carpus, microvascular epiphysis transfer, gradual correction using Ilizarov method, for Bayne Type III or Type IV...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28600857/quantification-of-tumor-uptake-with-molecular-breast-imaging
#4
Steven T Bache, Cheenu Kappadath
PURPOSE: We developed scatter and attenuation correction techniques for quantifying images obtained with Molecular Breast Imaging (MBI) systems. METHODS: To investigate scatter correction, energy spectra of a (99m) Tc point source were acquired with 0-7-cm-thick acrylic to simulate scatter between the detector heads. System-specific scatter correction factor, k, was calculated as a function of thickness using a dual-energy-window technique. To investigate attenuation correction, a 7-cm-thick rectangular phantom containing (99m) Tc-water simulating breast tissue and fillable spheres simulating tumors was imaged...
June 10, 2017: Medical Physics
https://www.readbyqxmd.com/read/28583055/fracture-of-the-distal-ulna-metaphysis-in-the-setting-of-distal-radius-fractures
#5
Nader Paksima, Sonya Khurana, Michael Soojian, Vipul Patel, Kenneth Egol
BACKGROUND: Fracture of the metaphyseal region of the distal ulna is an uncommon injury that has been reported to occur concomitantly with distal radius fracture. We aimed to report the incidence and types of distal ulnar head and neck fractures associated with distal radius fractures and compare outcomes in operatively versus non-operatively treated patients. METHODS: Over a 5-year period a distal radius fracture registry was maintained at our institution. Eleven of 512 consecutive patients had metaphyseal distal ulna fractures in association with distal radius fractures and at least 1-year follow-up...
April 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28567152/a-complicated-course-of-a-coronal-shear-fracture-type-iv-of-the-distal-part-of-humerus-resulting-in-resurfacing-radiocapitellar-joint-replacement
#6
Ingo Schmidt
BACKGROUND: Coronal shear fracture type IV of the distal part of humerus is a very rare injury with articular complexity potentially leading to posttraumatic osteoarthritis. One option for surgical treatment of advanced unicompartmental radiocapitellar osteoarthritis is resurfacing radiocapitellar joint replacement. METHOD: A 62-year- old female sustained a coronal shear fracture type IV of the distal part of left humerus that was primarily treated with open reduction and internal fixation using headless compression screws...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28489627/radial-head-ingrowth-anatomic-implant-vs-smooth-stem-monoblock-implant-in-acute-terrible-triad-injury-a-prospective-comparative-study
#7
David Rodriguez-Quintana, David Beaton, Natalie Rodriguez-Quintana, Francisco Lopez-Gonzalez
OBJECTIVE: This study aimed to compare clinical outcomes and radiographic findings between patients who received two different implants (smooth stemmed modular implant or an anatomic press fit implant) on patients with acute terrible triad injuries. DESIGN: Prospective cohort SETTING:: Level II Trauma center, University hospitalPatients/Participants: 34 patients with an isolated terrible triad injury were divided into two study groups (n= 17 each) with different set of radial head implants and followed for 2 years...
May 10, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28448834/cmc-prediction-for-ionic-surfactants-in-pure-water-and-aqueous-salt-solutions-based-solely-on-tabulated-molecular-parameters
#8
Stoyan I Karakashev, Stoyan K Smoukov
The critical micelle concentration (CMC) of various surfactants is difficult to predict accurately, yet often necessary to do in both industry and science. Hence, quantum-chemical software packages for precise calculation of CMC were developed, but they are expensive and time consuming. We show here an easy method for calculating CMC with a reasonable accuracy. Firstly, CMC0 (intrinsic CMC, absent added salt) was coupled with quantitative structure - property relationship (QSPR) with defined by us parameter "CMC predictor" f1...
April 18, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28437479/conformational-dynamics-of-bacterial-trigger-factor-in-apo-and-ribosome-bound-states
#9
Mehmet Tarik Can, Zeynep Kurkcuoglu, Gokce Ezeroglu, Arzu Uyar, Ozge Kurkcuoglu, Pemra Doruker
The chaperone trigger factor (TF) binds to the ribosome exit tunnel and helps cotranslational folding of nascent chains (NC) in bacterial cells and chloroplasts. In this study, we aim to investigate the functional dynamics of fully-atomistic apo TF and its complex with 50S. As TF accomodates a high percentage of charged residues on its surface, the effect of ionic strength on TF dynamics is assessed here by performing five independent molecular dynamics (MD) simulations (total of 1.3 micro-second duration) at 29 mM and 150 mM ionic strengths...
2017: PloS One
https://www.readbyqxmd.com/read/28412106/radial-notch-labralization-for-proximal-radioulnar-joint-dysplasia
#10
Enrico Bellato, Shawn W O'Driscoll
BACKGROUND: Chronic posterior subluxation or dislocation of the radial head is uncommon and difficult to treat. To restore radiocapitellar alignment, procedures such as deepening of the notch using a high-speed burr have been described, but they can result in cartilage damage. We hypothesized that a radial notch labralization using soft tissue could improve radiocapitellar tracking without violating the joint surface. METHODS: A radial notch labralization was performed in 3 patients with chronic posterior subluxation of the radial head and developmental dysplasia of the radial notch in the setting of complex recurrent instability of the elbow...
April 12, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28397714/effect-of-intravenous-pulse-dexamethasone-versus-daily-oral-prednisolone-on-bone-mineral-density-in-dermatology-patients-is-it-a-site-specific-response
#11
Sanjeev Handa, Gurjeet Singh, Amanjot Kaur Arora, Niranjan Khandelwal, Vivek Gupta
BACKGROUND: The use of glucocorticoids in various forms of administration is complicated by their systemic side effects. Although intravenous pulse therapy is considered to have lesser systemic side effects, there are few studies in literature comparing the effects of intravenous pulse glucocorticoids versus oral daily glucocorticoids on bone mineral density. AIM: To compare the effects of intravenous pulse glucocorticoids and oral daily glucocorticoids on bone mineral density with the aim of finding any site-specific osteopenic side effect...
April 10, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28379908/effects-of-long-term-high-load-exercise-on-the-anatomy-of-the-hip-joints-a-preliminary-report
#12
Yawei Song, Xiyuan Zhang, Ke Rong
The aim of this study was to assess the impact of different sports on hip joint anatomic parameters in athletes. This was a cross-sectional study of eight male trampolinists, eight male weightlifters, and eight male volunteers enrolled in July 2014. Hip joint anatomic parameters were measured from plain radiographs taken at the level of the lesser trochanter center. Data were compared between groups using the χ-test or one-way analysis of variance with the Bonferroni post-hoc test. There were no significant differences among groups in age, height, or weight...
April 4, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28360502/citation-analysis-of-the-100-most-common-articles-regarding-distal-radius-fractures
#13
Richard Jones, Travis Hughes, Kevin Lawson, Gregory DeSilva
PURPOSE: Bibliometric studies are increasingly being utilized as a tool for gauging the impact of different literature within a given field. The purpose of this study was to identify the most cited articles related to the management of distal radius fractures to better understand how the evidence of this topic has been shaped and changed over time. METHODS: We utilized the ISI web of science database to conduct a search for the term "distal radius fracture" under the "orthopaedics" research area heading, and sorted the results by number of times cited...
January 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28359893/spectroscopic-studies-on-the-gemini-surfactant-mediated-refolding-of-human-serum-albumin
#14
Nuzhat Gull, Javed Masood Khan, Rukhsana, Rizwan Hassan Khan
Refolding of guanidinium hydrochloride (GdCl) denatured human serum albumin (HSA) using a combination of cationic gemini surfactants; pentanediyl-α,ω-bis(cetyldimethylammonium bromide) (C16H33(CH3)2N(+)-(CH2)5-N(+)(CH3)2C16H33)2Br(-) designated as G5 and methyl- β-cyclodextrin, is attempted in the present study. The studies were carried out in an aqueous medium (pH 7.4) using dynamic light scattering (DLS), circular dichroism (CD) and fluorescence spectroscopy. A careful study of the DLS data indicates that against the hydrodynamic radius (Rh) of 3...
March 27, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28345405/thickness-distribution-of-glenohumeral-joint-cartilage
#15
Christoph Schleich, Bernd Bittersohl, Gerald Antoch, Rüdiger Krauspe, Christoph Zilkens, Jörn Kircher
High-resolution 3-dimensional cartilage-specific magnetic resonance imaging (MRI) was performed at 3 T to test the following hypotheses: (1) there is a nonuniform cartilage thickness distribution both on the proximal humerus and on the glenoid surface and (2) the glenohumeral joint as a combined system is congruent with the level of the joint cartilage surface without substantial radial mismatch. Inclusion of 38 volunteers (19 females, mean age 24.34 ± 2.22 years; range 21-29 years) in a prospective study...
April 2017: Cartilage
https://www.readbyqxmd.com/read/28344525/mri-correlation-of-radial-head-fractures-and-forearm-injuries
#16
Hisham Awan, Robert Goitz
Background: Radial head fractures can be associated with soft tissue injuries of the forearm and wrist. The Essex-Lopresti injury can lead to significant morbidity, especially if the diagnosis is not made acutely. Better identification of such injuries is needed to allow optimal surgical treatment and prevent long-term sequelae. We used magnetic resonance imaging (MRI) to correlate the degree of soft tissue injuries with radial head fractures. Methods: Sixteen pairs of forearms with an associated radial head fracture in 15 patients prospectively underwent an MRI within 2 weeks of their injury...
March 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28342168/bone-mass-in-boys-with-autism-spectrum-disorder
#17
Chadi A Calarge, Janet A Schlechte
To examine bone mass in children and adolescents with autism spectrum disorders (ASD). Risperidone-treated 5 to 17 year-old males underwent anthropometric and bone measurements, using dual-energy X-ray absorptiometry and peripheral quantitative computed tomography. Multivariable linear regression analysis models examined whether skeletal outcomes differed among participants with (n = 30) versus without ASD (n = 156). After adjusting for potential covariates, having ASD was associated with significantly lower trabecular bone mineral density and bone strength at the radius, and with marginally lower total body less head bone mineral content (p < 0...
March 25, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28320305/intermolecular-interactions-of-myosin-subfragment-1-induced-by-the-n-terminal-extension-of-essential-light-chain-1
#18
D S Logvinova, O P Nikolaeva, D I Levitsky
We applied dynamic light scattering (DLS) to compare aggregation properties of two isoforms of myosin subfragment 1 (S1) containing different "essential" (or "alkali") light chains, A1 or A2, which differ by the presence of an N-terminal extension in A1. Upon mild heating (up to 40°C), which was not accompanied by thermal denaturation of the protein, we observed a significant growth in the hydrodynamic radius of the particles for S1(A1), from ~18 to ~600-700 nm, whereas the radius of S1(A2) remained unchanged and equal to ~18 nm...
February 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28306622/treatment-of-forearm-deformity-with-radial-head-dislocation-because-of-multiple-osteochondromas-a-series-of-three-cases-treated-by-simple-axis-correction-and-distraction-osteogenesis-of-the-ulna
#19
Kousuke Iba, Megumi Hanaka, Yasuhiro Ozasa, Nobuyuki Takahashi, Kohei Kanaya, Toshihiko Yamashita
Radial head dislocation in multiple osteochondroma leads to functional impairment and cosmetic problems, and surgical intervention has not been successful to date, with high rates of redislocation. Simple correction of the longitudinal axis and distraction oste8ogenesis of the ulna without corrective osteotomy of the radius were performed within 1 year of radial head dislocation. The mean age of the patients was 7.2 years and the postoperative follow-up duration was 63.6 months. In all cases, the dislocated radial head was repositioned without surgical invention involving the radius...
March 16, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28302571/alpha-9-nicotinic-acetylcholine-receptors-mediate-hypothermic-responses-elicited-by-provocative-motion-in-mice
#20
Longlong Tu, Lauren Poppi, John Rudd, Ethan T Cresswell, Doug W Smith, Alan Brichta, Eugene Nalivaiko
Hypothermic responses accompany motion sickness in humans and can be elicited by provocative motion in rats. We aimed to determine the potential role in these responses of the efferent cholinergic vestibular innervation. To this end, we used knockout (KO) mice lacking α9 cholinoreceptor subunit predominantly expressed in the vestibular hair cells and CBA strain as a wild-type (WT) control. In WT mice, circular horizontal motion (1Hz, 4cm radius, 20min) caused rapid and dramatic falls in core body temperature and surface head temperature associated with a transient rise in the tail temperature; these responses were substantially attenuated in KO mice; changes were (WT vs...
March 14, 2017: Physiology & Behavior
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