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https://www.readbyqxmd.com/read/28222682/a-statistical-method-utilizing-information-of-imported-cases-to-estimate-the-transmissibility-for-an-influenza-pandemic
#1
Ka Chun Chong, Benny Chung Ying Zee, Maggie Haitian Wang
BACKGROUND: In a new influenza pandemic, travel data such as arrival times of cases seeded by the originating country can be regarded as a combination of the epidemic size and the mobility networks of infections connecting the originating country with other regions. It can be a complete and timely source for estimating the basic reproduction number (R 0 ), a key indicator of disease transmissibility. METHOD: In this study, we developed a likelihood-based method using arrival times of infected cases in different countries to estimate R 0 for influenza pandemics...
February 21, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28212544/protective-effect-of-dhea-on-hydrogen-peroxide-induced-oxidative-damage-and-apoptosis-in-primary-rat-leydig-cells
#2
Xiao Ding, Lei Yu, Chongyang Ge, Haitian Ma
Dehydroepiandrosterone (DHEA) is widely used as a nutritional supplement due to its putative anti-aging properties. However, the effect of DHEA in Leydig cells, a major target cell of DHEA biotransformation in male, are not clear. The present study aimed to investigate the preventative effect of DHEA on oxidative damage and apoptosis after H2O2 treatment in Leydig cells. The results showed that DHEA treatment attenuated the reduction of cell viability induced by H2O2. No differences were observed on the superoxide anion (O2-) content, while DHEA treatment decreased reactive oxygen species (ROS) and hydroxyl radical (•OH) content in H2O2-treated Leydig cells...
February 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28207688/transmission-of-zika-virus-haiti-october-12-2015-september-10-2016
#3
Ito Journel, Lesly L Andrécy, Dudley Metellus, Jean S Pierre, Rose Murka Faublas, Stanley Juin, Amber M Dismer, David L Fitter, Daniel Neptune, Marie José Laraque, Salomon Corvil, Manise Pierre, Josiane Buteau, Donald Lafontant, Roopal Patel, Jean Frantz Lemoine, David W Lowrance, Macarthur Charles, Jacques Boncy, Paul Adrien
Zika virus disease is caused by infection with a flavivirus with broad geographic distribution and is most frequently transmitted by the bite of an infected mosquito. The disease was first identified in the World Health Organization's Region of the Americas in 2015 and was followed by a surge in reported cases of congenital microcephaly in Brazil; Zika virus disease rapidly spread to the rest of the region and the Caribbean (1), including Haiti. Infection with the virus is associated with adverse fetal outcomes (1) and rare neurologic complications in adults...
February 17, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28192523/bead-based-immunoassay-allows-sub-picogram-detection-of-histidine-rich-protein-2-from-plasmodium-falciparum-and-estimates-reliability-of-malaria-rapid-diagnostic-tests
#4
Eric Rogier, Mateusz Plucinski, Naomi Lucchi, Kimberly Mace, Michelle Chang, Jean Frantz Lemoine, Baltazar Candrinho, James Colborn, Rafael Dimbu, Filomeno Fortes, Venkatachalam Udhayakumar, John Barnwell
Detection of histidine-rich protein 2 (HRP2) from the malaria parasite Plasmodium falciparum provides evidence for active or recent infection, and is utilized for both diagnostic and surveillance purposes, but current laboratory immunoassays for HRP2 are hindered by low sensitivities and high costs. Here we present a new HRP2 immunoassay based on antigen capture through a bead-based system capable of detecting HRP2 at sub-picogram levels. The assay is highly specific and cost-effective, allowing fast processing and screening of large numbers of samples...
2017: PloS One
https://www.readbyqxmd.com/read/28152996/quality-and-uptake-of-antenatal-and-postnatal-care-in-haiti
#5
Kelsey R Mirkovic, Eva Lathrop, Erin N Hulland, Reginald Jean-Louis, Daniel Lauture, Ghislaine Desinor D'Alexis, Endang Hanzel, Reynold Grand-Pierre
BACKGROUND: Despite improvement, maternal mortality in Haiti remains high at 359/100,000 live births. Improving access to high quality antenatal and postnatal care has been shown to reduce maternal mortality and improve newborn outcomes. Little is known regarding the quality and uptake of antenatal and postnatal care among Haitian women. METHODS: Exit interviews were conducted with all pregnant and postpartum women seeking care from large health facilities (n = 10) in the Nord and Nord-Est department and communes of St...
February 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28146335/women-s-and-healthcare-workers-beliefs-and-experiences-surrounding-abortion-the-case-of-haiti
#6
Laura Dean Albuja, Rosina Cianelli, Debbie Anglade, Brenda Owusu, Laly Joseph, Sonique Sailsman, Lilian Ferrer
PURPOSE: Women in developing countries usually encounter serious inequities in terms of women's health. To date, there is limited understanding of abortion from the perspective of Haitian women. As a limited-resource country, Haiti faces complex social issues and healthcare challenges. With abortion being illegal, many adult and teenage women seek clandestine abortions. The aim of this study was to explore and gain a greater understanding of women's and healthcare workers' beliefs and experiences about abortion in Haiti...
February 1, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28134005/chlamydia-trachomatis-neisseria-gonorrhoeae-and-trichomonas-vaginalis-screening-and-treatment-of-pregnant-women-in-port-au-prince-haiti
#7
Claire C Bristow, Patricia Mathelier, Oksana Ocheretina, Daphne Benoit, Jean W Pape, Adriane Wynn, Jeffrey D Klausner
In Haiti, routine screening for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) among pregnant women is not conducted; yet these sexually transmitted infections (STIs) are associated with adverse birth and newborn health outcomes. We aimed to assess the acceptability and feasibility of screening and the prevalence of STIs among pregnant women in Port-au-Prince, Haiti. Pregnant women of at least 18 years of age who attend Haitian Study Group for Kaposi's sarcoma and Opportunistic Infections (GHESKIO) clinics in Port-au-Prince, Haiti provided self-collected vaginal swab specimens...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28129137/tracking-disease-digital-epidemiology-offers-new-promise-in-predicting-outbreaks
#8
Mary Bates
On 19 October 2010, ten months after a devastating earthquake hit Haiti, the Haitian Ministry of Public Health and Population (MSPP) was notified of a sudden surge in patients suffering from watery diarrhea and dehydration. Two days later, the Haiti National Public Health Laboratory identified the culprit: Vibrio cholerae. On 22 October, officials announced the first cholera outbreak in Haiti in more than a century.
January 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28114652/feasibility-of-fecal-immunochemical-testing-among-hispanic-and-haitian-immigrants-living-in-south-florida
#9
Natasha Schaefer Solle, Daniel A Sussman, Tulay Koru-Sengul, Julia Seay, Jordan Baeker-Bispo, Erin N Kobetz
No abstract text is available yet for this article.
January 23, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28111146/interpreting-the-transmissibility-of-measles-in-two-different-post-periods-of-supplementary-immunization-activities-in-hubei-china
#10
Ka Chun Chong, Chi Zhang, Benny Chung Ying Zee, Tongyong Luo, Lei Wang, Greta Chun Huen Tam, Katherine Min Jia, Riyang Sun, Maggie Haitian Wang, Xuhua Guan
Although evidence has shown that supplementary immunization activity (SIA) campaigns greatly reduce the incidence of measles, their effects on disease transmissibility have seldom been monitored. A great decrease in the number of cases may be a false signal of early success towards measles elimination to policy makers. By interpreting the transmissibility in two different post-SIA periods in Hubei, China, the current study showed sustained measles transmissions despite a reduced number of cases. Two population-based cross-sectional serological surveys of measles antibodies were conducted in Hubei province in mid-2010 and mid-2011 after the implementation of SIAs...
January 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28109483/otorhinolaryngology-head-and-neck-surgery-in-a-low-income-country-the-haitian-experience
#11
Maxwell P Kligerman, Anahuma Alexandre, Patrick Jean-Gilles, David Walmer, Mack L Cheney, Anna H Messner
OBJECTIVE: Little is known regarding the diagnosis and management of pediatric surgical conditions of the head and neck in low-income countries. Haiti, the western hemisphere's poorest country, recently developed its first Otorhinolaryngology (ORL) department at the Hopital de L'Universite d'Etat d'Haiti (HUEH). This manuscript assesses the caseload at HUEH with a special emphasis on pediatric cases, with the aim of characterizing ORL related conditions and their treatments in low-income countries...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28106279/a-rapid-electrochemical-monitoring-platform-for-sensitive-determination-of-thiamethoxam-based-on-%C3%AE-cyclodextrin-graphene-composite
#12
XingChen Zhai, Hua Zhang, Min Zhang, Xin Yang, Cheng Gu, GuoPeng Zhou, Haitian Zhao, Zhenyu Wang, Aijun Dong, Jing Wang
A rapid monitoring platform for sensitive voltammetric detection of thiamethoxam (TMX) residues was reported in the present study. The β-cyclodextrin-reduced graphene oxide composite (β-CD-rGO) was used as a reinforcing material in electrochemical determination of TMX. Compared with bare glassy carbon electrode (GCE), the reduction peak currents of TMX at rGO/GCE and β-CD-rGO/GCE were increased by 70 and 124 folds, respectively. The experimental conditions influencing voltammetric determination of TMX, such as the amount of β-CD-rGO, solution pH, temperature and time on accumulation, were optimized...
January 20, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28091538/mircorna-145-promotes-activation-of-hepatic-stellate-cells-via-targeting-kr%C3%A3-ppel-like-factor-4
#13
Ruoting Men, Maoyao Wen, Mingyue Zhao, Xuelian Dan, Zongze Yang, Wenchao Wu, Maggie Haitian Wang, Xiaojing Liu, Li Yang
Krüppel-like Factor 4 (KLF4), a target gene of miR-145, can negatively regulate lung fibrosis. However, the potential role of KLF4 and miR-145 in hepatic stellate cells (HSCs) activation or in hepatic fibrosis keeps unclear. This study aims to characterize miR-145 and KLF4 in activated HSCs and liver cirrhotic, and the underlying molecular basis. miR-145 was significantly up-regulated, while KLF4 was dramatically down-regulated during the activation of rat primary HSCs and TGF-βtreated HSCs. Furthermore, miR-145 mimics induced and inhibition of miR-145 reduced α-SMA and COL-I expression in primary HSCs...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28086983/mailed-hpv-self-sampling-for-cervical-cancer-screening-among-underserved-minority-women-study-protocol-for-a-randomized-controlled-trial
#14
Erin Kobetz, Julia Seay, Anthony Amofah, Larry Pierre, Jordan Baeker Bispo, Dinah Trevil, Martha Gonzalez, Martine Poitevien, Tulay Koru-Sengul, Olveen Carrasquillo
BACKGROUND: Underserved ethnic minority women experience significant disparities in cervical cancer incidence and mortality, mainly due to lack of cervical cancer screening. Barriers to Pap smear screening include lack of knowledge, lack of health insurance and access, and cultural beliefs regarding disease prevention. In our previous SUCCESS trial, we demonstrated that HPV self-sampling delivered by a community health worker (CHW) is efficacious in circumventing these barriers. This approach increased screening uptake relative to navigation to Pap smear screening...
January 13, 2017: Trials
https://www.readbyqxmd.com/read/27987670/application-of-acellular-intima-from-porcine-thoracic-aorta-in-full-thickness-skin-wound-healing-in-a-rat-model
#15
Haitian Fu, Liping Teng, RuiZhen Bai, Chao Deng, Guozhong Lv, Jinghua Chen
The tunica intima of aorta is made up of one layer of smooth endothelium and basement membrane. The basement membrane is rich in extracellular matrix (ECM) molecules, including collagen, glycosaminoglycans (e.g., heparan sulfate), proteoglycans (e.g., perlecan), and glycoproteins. All or most of these components are involved in wound healing process. In this work, we determined whether the acellular intima from porcine thoracic aorta can be a new kind of xenograft to repair the skin-wound surface in a rat model...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27977644/assessing-change-in-avian-influenza-a-h7n9-virus-infections-during-the-fourth-epidemic-china-september-2015-august-2016
#16
Nijuan Xiang, Xiyan Li, Ruiqi Ren, Dayan Wang, Suizan Zhou, Carolyn M Greene, Ying Song, Lei Zhou, Lei Yang, C Todd Davis, Ye Zhang, Yali Wang, Jian Zhao, Xiaodan Li, A Danielle Iuliano, Fiona Havers, Sonja J Olsen, Timothy M Uyeki, Eduardo Azziz-Baumgartner, Susan Trock, Bo Liu, Haitian Sui, Xu Huang, Yanping Zhang, Daxin Ni, Zijian Feng, Yuelong Shu, Qun Li
Since human infections with avian influenza A(H7N9) virus were first reported by the Chinese Center for Disease Control and Prevention (China CDC) in March 2013 (1), mainland China has experienced four influenza A(H7N9) virus epidemics. Prior investigations demonstrated that age and sex distribution, clinical features, and exposure history of A(H7N9) virus human infections reported during the first three epidemics were similar (2). In this report, epidemiology and virology data from the most recent, fourth epidemic (September 2015-August 2016) were compared with those from the three earlier epidemics...
December 16, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27941464/end-of-life-in-a-haitian-american-faith-based-community-caring-for-family-and-communal-unity
#17
Susan Charlotte Ladd, Shirley C Gordon
This article presents two models resulting from a grounded theory study of the end-of-life decision-making process for Haitian Americans. Successful access to this vulnerable population was achieved through the faith-based community. The first model describes this faith-based community of Haitian Americans. The second model describes the process used by families in this community who must make end-of-life healthcare decisions. Implications for nursing practice and caring science include a need to improve the congruence between the nursing care provided at this vulnerable time and the cultural values of a population...
January 2017: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
https://www.readbyqxmd.com/read/27924972/protective-mechanisms-of-purified-polyphenols-from-pinecones-of-pinus-koraiensis-on-spleen-tissues-in-tumor-bearing-s180-mice-in-vivo
#18
Juanjuan Yi, Cuilin Cheng, Xiaoyu Li, Haitian Zhao, Hang Qu, Zhenyu Wang, Lu Wang
The previous study evaluated the antitumor activity and the underlying mechanism of the purified polyphenols from pinecones of Pinus koraiensis (PPP-40) using a tumor-bearing S180 mice model. This study was designed to evaluate the protective effects of PPP-40 on spleen tissues of S180 mice in vivo. Pretreatment with PPP-40 (150 mg per kg BW per D) could significantly inhibit tumor growth, enhance spleen index and prevent the decline of haematological parameters of S180 mice induced by the tumor microenvironment...
December 7, 2016: Food & Function
https://www.readbyqxmd.com/read/27919757/dietary-administration-of-bacillus-subtilis-hainup40-enhances-growth-digestive-enzyme-activities-innate-immune-responses-and-disease-resistance-of-tilapia-oreochromis-niloticus
#19
Haitian Liu, Shifeng Wang, Yan Cai, Xiaohui Guo, Zhenjie Cao, Yongzheng Zhang, Shubin Liu, Wei Yuan, Weiwei Zhu, Yu Zheng, Zhenyu Xie, Weiliang Guo, Yongcan Zhou
The probiotic properties of Bacillus subtilis HAINUP40 isolated from the aquatic environment, and the effects of dietary administration of B. subtilis HAINUP40 on the growth performance, intestinal probiotic recovery, digestive enzyme activities, innate immunity and disease resistance of tilapia (Oreochromis niloticus) were evaluated. The probiotic properties investigated include tolerance to simulated gastrointestinal stress, auto-aggregation, cell surface hydrophobicity and extracellular enzyme production...
December 2, 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27906806/awareness-of-cervical-cancer-causes-and-predeterminants-of-likelihood-to-screen-among-women-in-haiti
#20
Schatzi H McCarthy, Kathy A Walmer, Joel C Boggan, Margaret W Gichane, William A Calo, Harry A Beauvais, Noel T Brewer
OBJECTIVES: Cervical cancer is the leading cause of cancer deaths among women in Haiti. Given this high disease burden, we sought to better understand women's knowledge of its causes and the sociodemographic and health correlates of cervical cancer screening. MATERIALS AND METHODS: Participants were 410 adult women presenting at clinics in Léogâne and Port-au-Prince, Haiti. We used bivariate and multivariate logic regression to identify correlates of Pap smear receipt...
January 2017: Journal of Lower Genital Tract Disease
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