Read by QxMD icon Read


Belén Irarrázaval, Salesa Barja, Edson Bustos, Romel Doirsaint, Gloria Senethmm, María Paz Guzmán, Ricardo Uauy
Infant malnutrition remains an important cause of death and disability, and Haiti has the highest prevalence in the Americas. Therefore, preventive strategies are needed. Our aims were (1) To assess the prevalence of malnutrition among young children seen at a health center in Haiti; (2) Examine adherence to infant feeding practices recommended by the World Health Organization (WHO) and the association to nutritional status. This cross-sectional study recruited children from the Saint Espri Health Center in Port Au Prince in 2014...
March 20, 2018: Nutrients
Longlong Li, Jinlong Zhao, Chongyang Ge, Lei Yu, Haitian Ma
This study aimed to investigate the molecular mechanism of dehydroepiandrosterone (DHEA) rehabilitated BRL-3A cells oxidative stress damage induced by hydrogen peroxide (H2 O2 ). Results showed that DHEA reversed the decrease of cell viability and ameliorated nuclear chromatin damage in H2 O2 -induced BRL-3A cells. DHEA increased the activities of superoxide dismutase, catalase, peroxidase, and glutathione peroxidase, and decreased the reactive oxygen species (ROS) production in H2 O2 -induced BRL-3A cells...
March 9, 2018: Journal of Cellular Physiology
Elena Cyrus, Diana M Sheehan, Kristopher Fennie, Mariana Sanchez, Christyl T Dawson, Marsha Cameron, Lorene Maddox, Mary Jo Trepka
Prompt HIV diagnosis decreases the risk of HIV transmission and improves health outcomes. The study objective was to examine rates of delayed HIV diagnosis among non-Latino Black Caribbean immigrants in Florida. The sample included 39,008 Black HIV-positive individuals, aged 13 or older from the Caribbean and the mainland U.S. Delayed HIV diagnosis was defined as AIDS diagnosis within three months of HIV diagnosis. After adjusting for demographic factors, year of HIV diagnosis, transmission mode, neighborhood level socioeconomic status, and rural-urban residence, a disparity persisted for Caribbean-born Blacks in the Bahamas and Haiti compared with U...
2018: Journal of Health Care for the Poor and Underserved
Xingchen Zhai, Haitian Zhao, Min Zhang, Xin Yang, Jingming Sun, Yongxin She, Aijun Dong, Hua Zhang, Lei Yao, Jing Wang
A new 3‑aminophenylboronic acid-functionalized stationary phase based on silica for hydrophilic interaction liquid chromatography (HILIC) was developed and showed great HILIC characteristics on separation for chito‑oligosaccharides. The material was synthesized by grafting 3‑aminophenylboronic acid group to silica, and it was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), elemental analysis and thermal gravimetric analysis (TGA). Nucleobases and nucleosides were used to evaluate the retention property and to investigate retention mechanism by the models designed for description of partitioning and surface adsorption through adjusting ratio of water in the mobile phase...
February 28, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Jessica Miller, Marvin L Birnbaum
In October 2010, the Haitian Ministry of Public Health and Population (MSPP; Port au Prince, Haiti) reported a cholera epidemic caused by contamination of the Artibonite River by a United Nation Stabilization Mission camp. Interventional studies of the subsequent responses, including a descriptive Methods section and systematic approach, may be useful in facilitating comparisons and applying lessons learned to future outbreaks. The purpose of this study was to examine publicly available documents relating to the 2010 cholera outbreak to answer: (1) What information is publicly available on interventional studies conducted during the epidemic, and what was/were the impact(s)? and (2) Can the interventions be compared, and what lessons can be learned from their comparison? A PubMed (National Center for Biotechnology Information, National Institutes of Health; Bethesda, Maryland USA) search was conducted using the parameters "Haiti" and "cholera...
February 19, 2018: Prehospital and Disaster Medicine
Chengying Xie, Xiaozhe Wan, Haitian Quan, Mingyue Zheng, Li Fu, Yun Li, Liguang Lou
Abrogating tumor angiogenesis by inhibiting vascular endothelial growth factor receptor-2 (VEGFR2) has been established as a therapeutic strategy for treating cancer. However, because of their low selectivity, most small molecule inhibitors of VEGFR2 tyrosine kinase exhibit unexpected adverse effects and limited anti-cancer efficacy. In this study, we detailed the pharmacologic properties of anlotinib, a highly potent and selective VEGFR2 inhibitor, in preclinical models. Anlotinib occupied the ATP-binding pocket of the VEGFR2 tyrosine kinase and showed high selectivity and inhibitory potency (IC50 < 1 nM) for VEGFR2 relative to other tyrosine kinases...
February 15, 2018: Cancer Science
Kangkang Zhi, Haitian Zhao, Xin Yang, Hua Zhang, Jiacheng Wang, Jing Wang, Joe M Regenstein
Since the late 1980s, low molecular weight gelators (LMWGs) based on different classes of natural products have been reported. Until 2011, pure natural LMWGs (i.e., natural product gelators, NPGs) were not found. However, today only five NPGs are reported. We think that this may be due to the lack of awareness about the importance of NPGs and suitable methods to discover new NPGs. Here we illustrate the potential significance of NPGs, and present a general and efficient method for obtaining NPGs from organisms, which provides specific and important guidance to researchers for easy discovery of new NPGs from organisms in the future...
February 9, 2018: Nanoscale
Maliheh Mohamadpour, Genevieve Gabriel, Arthur C Grant
Unverricht-Lundborg disease (ULD) is an autosomal recessive progressive myoclonic epilepsy. The prevalence is highest in specific European countries and North Africa. Affected individuals have myoclonic and tonic-clonic seizures and a variable degree of ataxia and cognitive impairment. We report a native Haitian woman with ULD who was wheelchair bound due to nearly continuous myoclonic seizures exacerbated by activity and emotional distress. The seizures and their dramatic increase with volitional activity were recorded during video electroencephalography monitoring...
September 2017: Case Reports in Neurology
Antony Dalziel McNeil Stewart
This article examines anti-treponematoses work as part of US occupation public health policy in Haiti, a unique event in the history of international health. Yaws was highly prevalent in Haiti, but occupation doctors initially ignored it because of its close association with syphilis and stigmas attached to sexually transmitted disease. This changed when C.S. Butler asserted that yaws was "innocent" and that the two diseases should therefore be considered as one. Treatment increased as an anti-treponematoses campaign was now believed to hold great benefits for the occupation's paternalist and strategic aims, even though it ultimately failed...
October 2017: História, Ciências, Saúde—Manguinhos
Fabiano Tonaco Borges, Ana Paula Muraro, Luís Henrique da Costa Leão, Luciana de Andrade Carvalho, Carlos Eduardo Gomes Siqueira
We analyzed the sociodemographic profile, migration journey, health conditions, and health care access and utilization among recent Haitian immigrants to the Brazilian Amazon state of Mato Grosso. We conducted a cross-sectional study with a probabilistic sample of 452 Haitians. We administered a bilingual questionnaire from December 2014 to February 2015. Data were analyzed using chi square tests to evaluate differences among groups. The majority of participants were married men younger than 35 years old. They mostly came from the Haiti's Artibonite Department, living in Brazil for less than a year...
January 25, 2018: Journal of Immigrant and Minority Health
Abbey Mahon, Roodeline Valcourt, Lisa Merry, Fabiola Dieudonné, Jodi Tuck
BACKGROUND: Continuing education is an integral part of nursing professional development and improving healthcare delivery, but literature on continuing education initiatives in low-resource settings is limited. PURPOSE: To describe the creation and integration of a nurse educator (NE) position in two Haitian hospitals and highlight barriers and facilitators experienced by the NEs in their role. METHODS: Four NEs and three support staff involved in the creation and integration of the NE positions were interviewed...
January 24, 2018: Nursing Forum
Kemesha S Gabbidon, Mary Shaw-Ridley
This study characterized (a) mothers' childhood and teenage experiences with sex conversations and (b) families' perceptions of current parent-child sex conversations within two underserved Afro-Caribbean communities in the U.S. Fourteen dyads comprised of Haitian and Jamaican mothers and teens (aged 14-18) living in Miami, Florida, completed semi-structured interviews sharing their experiences with sex conversations. Researchers analyzed data using thematic content analysis. Mothers' mean age was 41.85 years, (SD = 5...
January 18, 2018: Journal of Immigrant and Minority Health
Tod G Hamilton, Tiffany L Green
Due in large part to increased migration from Africa and the Caribbean, black immigrants and their descendants are drastically changing the contours of health disparities among blacks in the United States. While prior studies have examined health variation among black immigrants by region of birth, few have explored the degree of variation in health behaviors, particularly smoking patterns, among first- and second- generation black immigrants by ancestral heritage. Using data from the 1995-2011 waves of the Tobacco Use Supplements of the Current Population Survey (TUS-CPS), we examine variation in current smoking status among first-, second-, and third/higher- generation black immigrants...
December 2017: SSM—Population Health
Xi Yu, Xingchun Gou, Peng Wu, Liang Han, Daofeng Tian, Fengyi Du, Zeming Chen, Fuyao Liu, Gang Deng, Ann T Chen, Chao Ma, Jun Liu, Sara M Hashmi, Xing Guo, Xiaolong Wang, Haitian Zhao, Xinran Liu, Xudong Zhu, Kevin Sheth, Qianxue Chen, Louzhen Fan, Jiangbing Zhou
Clinical translation of therapeutic peptides, particularly those that require penetration of the cell membrane or are cytolytic, is a major challenge. A novel approach based on a complementary mechanism, which has been widely used for guided synthesis of DNA or RNA nanoparticles, for de novo design of activatable protein nanoparticles (APNPs) for targeted delivery of therapeutic peptides is described. APNPs are formed through self-assembly of three independent polypeptides based on pairwise coiled-coil dimerization...
January 8, 2018: Advanced Materials
Mengling Peng, Shengnan Li, Qianian He, Jinlong Zhao, Longlong Li, Haitian Ma
BACKGROUND: Chicken embryos are widely used as a model for studies of obesity; however, no detailed information is available about the dynamic changes of proteins during the regulation of adipose biology and metabolism. Thus, the present study used an isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic approach to identify the changes in protein abundance at different stages of chicken embryonic development. RESULTS: In this study, the abundances of 293 hepatic proteins in 19-day old of chicken embryos compared with 14-day old and 160 hepatic proteins at hatching compared with 19-day old embryos were significantly changed...
January 8, 2018: BMC Genomics
H Velasco, R Torres Astorga, D Joseph, J S Antoine, L Mabit, A Toloza, G Dercon, Des E Walling
Large-scale deforestation, intensive land use and unfavourable rainfall conditions are responsible for significant continuous degradation of the Haitian uplands. To develop soil conservation strategies, simple and cost-effective methods are needed to assess rates of soil loss from farmland in Haiti. The fallout radionuclide caesium-137 (137Cs) provides one such means of documenting medium-term soil redistribution rates. In this contribution, the authors report the first use in Haiti of 137Cs measurements to document soil redistribution rates and the associated pattern of erosion/sedimentation rates along typical hillslopes within a traditional upland Haitian farming area...
December 21, 2017: Journal of Environmental Radioactivity
Chao Deng, Haitian Fu, Jingying Shang, Jinghua Chen, Xin Xu
The polysaccharides (DIP) extracted from Dictyophora indusiate has been found featuring great anti-cancer activity through enhancing organism immunity ability, and the DIP-induced macrophages activation might be mediated via TLR4/NF-κB signaling pathway. In this work, we make further investigation of the effect of DIP on macrophages and whether there was another pathway to regulate the immunoenhancement effect of DIP. The results showed that DIP could activate macrophages, causing the enhancement of its phagocyte activity, and then increase the secretion of IL-1β and TNF-α...
December 20, 2017: International Journal of Biological Macromolecules
P Kumar, S Karmakar, R Prasad, R Chopra, S Khandelwal, S Gupta, A C Dhariwal, P Yadav, P K Yadava
Cholera toxin (CT) is the principal virulence factor of Vibrio cholerae for fatal cholera diarrhoea. Serogroups O1 and O139 harbour CT and are known to be epidemic strains. The remaining serogroups (nonO1/nonO139) are non-toxigenic and may be associated with mild disease. O1 serogroup emerged with a variant of CT known as Haitian cholera toxin (HCT). The HCT strains are hypervirulent and have been associated with severe cholera outbreaks in India, Western Africa and Haiti. Here, we report the presence of HCT ( ctxB7 ) in a nonO1/nonO139 isolate causing persistent diarrhoea...
January 2018: New Microbes and New Infections
Daniela Ceccarelli, Geneviève Garriss, Seon Y Choi, Nur A Hasan, Ramunas Stepanauskas, Mihai Pop, Anwar Huq, Rita R Colwell
We report the complete sequence of two novel plasmids, pSDH-1 and pSDH-2, isolated from clinical Vibrio cholerae non-O1/non-O139 during the early phase of the 2010 Haitian cholera epidemic. Plasmids were revealed by employing single-cell genomics and their genome content suggests self-mobilization and, for pSDH-2, a toxin-antitoxin (TA) system for plasmid stabilization was identified. The putative origin of replication of pSDH-2 was mapped suggesting it replicates following the ColE1 model of plasmid replication...
2017: Frontiers in Microbiology
Phuong N Pham, Niamh Gibbons, Patrick Vinck
Introduction: In August 2016, the United Nations (U.N.) Secretary General acknowledged the U.N.'s role in the cholera epidemic that has beset Haiti since 2010. Two months later, the Secretary General issued a historic apology to the Haitian people before the U.N. General Assembly, for the organization's insufficient response to the cholera outbreak. These steps are part of the U.N.'s "new approach" to cholera in Haiti, which also includes launching a material assistance package for those most affected by cholera...
October 23, 2017: PLoS Currents
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"