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cerebral blood flow velocity

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https://www.readbyqxmd.com/read/29333725/chemoreflex-function-and-brain-blood-flow-during-upright-posture-in-men-and-women
#1
Christopher Hazlett, Heather Edgell
Orthostatic intolerance is more common in women than men, and some studies have found that women in the early follicular (EF) phase of the menstrual cycle experience the greatest feelings of lightheadedness. Chemoreflex function while supine or upright was investigated to determine the potential contribution of ventilatory control to these phenomena. Men (n = 13) and women (n = 14) were tested while supine and 70° upright (head-up tilt [HUT]) and given: (1) normoxia or (2) hypercapnia (5% CO2 ). Women were tested during the EF phase (days 2-5) and the midluteal phase (ML; days 18-24)...
January 2018: Physiological Reports
https://www.readbyqxmd.com/read/29305914/the-comparison-of-monitoring-of-cerebral-blood-flow-by-c-flow-and-transcranial-doppler-in-carotid-endarterectomy
#2
Xu Wang, Bin Yang, Yan Ma, Peng Gao, Yabing Wang, Yanfei Chen, Liqun Jiao, Feng Ling, Guoguang Zhao
OBJECTIVE: To prospectively compare the use of the c-FLOW (cerebral blood flow monitor) and transcranial Doppler (TCD) as two techniques for assessing brain perfusion during carotid endarterectomy (CEA). METHODS: This was a prospective, single center, observational study. All patients were monitored using c-FLOW and TCD during the operation. Changes from baseline values of cerebral blood flow index (CFI) and blood flow velocity of middle cerebral artery (V-MCA) were recorded following carotid artery clamping and unclamping...
January 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29288194/increased-middle-cerebral-artery-mean-blood-flow-velocity-index-after-stroke-thrombectomy-indicates-increased-risk-for-intracranial-hemorrhage
#3
Markus Kneihsl, Kurt Niederkorn, Hannes Deutschmann, Christian Enzinger, Birgit Poltrum, Renate Fischer, Daniela Thaler, Christina Hermetter, Gerit Wünsch, Franz Fazekas, Thomas Gattringer
BACKGROUND AND PURPOSE: Cerebral hyperperfusion has been related to the risk of intracranial hemorrhage (ICH) in stroke patients after vessel recanalization therapy. We hypothesized that after successful mechanical thrombectomy for acute anterior circulation stroke, hemodynamics detectable by transcranial Duplex (TCD) sonography would vary, and that increased blood flow velocities would be associated with ICH. METHODS: We retrospectively identified all ischemic stroke patients with successful endovascular recanalization for anterior circulation vessel occlusion (Thrombolysis in Cerebral Infarction 2b-3) between 2010 and 2017...
December 28, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29260615/preliminary-evidence-for-cerebral-capillary-shunting-in-adults-with-sickle-cell-anemia
#4
Meher R Juttukonda, Manus J Donahue, Larry T Davis, Melissa C Gindville, Chelsea A Lee, Niral J Patel, Adetola A Kassim, Sumit Pruthi, Jeroen Hendrikse, Lori C Jordan
Elevated flow velocities in adults with sickle cell anemia (SCA) may cause rapid erythrocyte transit through capillaries. This phenomenon could present as dural venous sinus hyperintensity on arterial spin labeling (ASL)-MRI and could be indicative of capillary shunting. Here, the prevalence of ASL venous hyperintensities and association with relevant physiology in adults with SCA was investigated. SCA ( n = 46) and age-matched control ( n = 16) volunteers were recruited for 3.0 T MRI. Pseudo-continuous ASL-MRI was acquired for cerebral blood flow (CBF) calculation and venous hyperintensity determination; venous signal intensity and a categorical venous score (three raters; 0 = no hyperintensity, 1 = focal hyperintensity, and 2 = diffuse hyperintensity) were recorded...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29249541/cerebrospinal-fluid-biomarkers-of-alzheimer-s-disease-are-associated-with-carotid-plaque-score-and-hemodynamics-in-intra-and-extra-cranial-arteries-on-ultrasonography
#5
Minoru Kouzuki, Masaya Nagano, Tetsuya Suzuki, Yuto Katsumata, Syouta Nakamura, Ayumi Takamura, Katsuya Urakami
Carotid plaque score (PS) and hemodynamic abnormalities in intra- and extra-cranial arteries are related to Alzheimer's disease (AD) progression. As these parameters are measured conveniently and non-invasively by ultrasonography, we examined their association with cerebral spinal fluid (CSF) AD biomarkers amyloid β (Aβ) and phosphorylated tau (p-tau). Carotid PS, mean flow velocity (MFV) in multiple intra- and extra-cranial arteries, CSF Aβ42 and p-tau, neurocognitive function (assessed by the Mini-Mental State Examination and Alzheimer's Disease Assessment Scale-cognitive subscale, Japanese version), and blood lipids (total cholesterol, HDL cholesterol, LDL cholesterol, and triglyceride) were measured in AD patients (n = 42), mild cognitive impairment patients (n = 20), and cognitively normal controls (n = 18)...
December 14, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29249075/the-characteristics-of-transcranial-color-coded-duplex-sonography-in-children-with-cerebral-arteriovenous-malformation-presenting-with-headache
#6
Vlasta Duranovic, Katarina Vulin, Ivana Dakovic, Jasna Lenicek Krleza, Sanja Delin, Ivana Galinovic, Josip Marjanovic, Ana Tripalo Batos, Zdenka Plesa Premilovac, Vlatka Mejaski Bosnjak
PURPOSE: Cerebral arteriovenous malformations (AVM) are uncommon lesions. They are most often presented in childhood as intracranial hemorrhage. The aim of this report is to present the use of transcranial color-coded duplex sonography (TCCS) in detection of AVMs in children suffering headache. METHODS: This report describes five pediatric patients with headache and cerebral AVM which were initially discovered by TCCS. Diagnosis was confirmed by magnetic resonance imaging and digital subtraction angiography...
December 16, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29247478/chinese-medicine-tongxinluo-capsule-alleviates-cerebral-microcirculatory-disturbances-in-ischemic-stroke-by-modulating-vascular-endothelial-function-and-inhibiting-leukocyte-endothelial-cell-interactions-in-mice-a-two-photon-laser-scanning-microscopy-study
#7
Shen Liu, Cong Wei, Ning Kang, Qilong He, Junqing Liang, Hongtao Wang, Liping Chang, Daohong Chen, Qiuyan Zhang, Chengcheng Chang, Junfang Zhang, Hong Ren, Yiling Wu
OBJECTIVE: The aim of this study was to examine the effect of Tongxinluo capsule (TXL), a Chinese medicine prescription, on cerebral microcirculatory disturbances after permanent middle cerebral artery occlusion (pMCAO) in mice using two-photon laser scanning microscopy (TPLSM) and further explore the underlying mechanisms. METHODS: C57BL/6J mice were subjected to pMCAO and orally administered with TXL (3.0, 1.5 and 0.75 g/kg/day) at 1h, 3h and 21h after pMCAO. The following parameters were examined at 6h and 24h after pMCAO: neurological deficit, infarct volume, blood-brain barrier (BBB) permeability, cerebral microvessel structure, brain microcirculation (TPLSM imaging), vasoactive factors and adhesion molecules...
December 15, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/29246907/a-new-combined-parameter-predicts-re-treatment-for-coil-embolized-aneurysms-a-computational-fluid-dynamics-multivariable-analysis-study
#8
Soichiro Fujimura, Hiroyuki Takao, Takashi Suzuki, Chihebeddine Dahmani, Toshihiro Ishibashi, Hiroya Mamori, Makoto Yamamoto, Yuichi Murayama
PURPOSE: Coil embolization is a minimally invasive method used to treat cerebral aneurysms. Although this endovascular treatment has a high success rate, aneurysmal re-treatment due to recanalization remains a major problem of this method. The purpose of this study was to determine a combined parameter that can be useful for predicting aneurysmal re-treatment due to recanalization. METHODS: Patient-specific geometries were used to retrospectively analyze the blood flow for 26 re-treated and 74 non-retreated aneurysms...
December 15, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29243981/assessment-of-intracranial-venous-blood-flow-after-subarachnoid-hemorrhage-a-new-approach-to-diagnose-vasospasm-with-transcranial-color-coded-duplex-sonography
#9
Florian Connolly, Stephan J Schreiber, Christoph Leithner, Georg Bohner, Peter Vajkoczy, José M Valdueza
OBJECTIVE Transcranial color-coded duplex sonography (TCCS) is a reliable tool that is used to assess vasospasm in the M1 segment of the middle cerebral artery (MCA) after subarachnoid hemorrhage (SAH). A distinct increase in blood flow velocity (BFV) is the principal criterion for vasospasm. The MCA/internal carotid artery (ICA) index (Lindegaard Index) is also widely used to distinguish between vasospasm and cerebral hyperperfusion. However, extracranial ultrasonography assessment of the neck vessels might be difficult in an intensive care unit...
December 15, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29239696/compression-garments-and-cerebral-blood-flow-influence-on-cognitive-and-exercise-performance
#10
Brittany A Smale, Joseph M Northey, Disa J Smee, Nathan G Versey, Ben Rattray
This study aimed to describe the effect of compression garments on middle cerebral artery blood flow velocity (MCAv) in relation to cognitive and exercise performance whilst cycling. In a randomised-controlled-cross-over design, 15 well-trained male cyclists were recruited to participate in three identical trials wearing loose fitting shorts (control), low-grade, or medium-grade compression garments. The protocol involved four 8 min increments of cycling at 30%, 50%, 70%, and 85% maximal power output and a 4 km time-trial...
December 14, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/29235099/variations-from-morning-to-afternoon-of-middle-cerebral-and-umbilical-artery-blood-flow-and-fetal-heart-rate-variability-and-fetal-characteristics-in-the-normally-developing-fetus
#11
Tehila Avitan, Ari Sanders, Ursula Brain, Dan Rurak, Tim F Oberlander, Ken Lim
OBJECTIVE: To determine if there are changes in maternal uterine blood flow, fetal brain blood flow, fetal heart rate variability, and umbilical blood flow between morning (AM) and afternoon (PM) in healthy, uncomplicated pregnancies. STUDY DESIGN: In this prospective study, 68 uncomplicated singleton pregnancies (mean 35 + 0.7 weeks gestation) underwent a standard observational protocol at both 08:00 (AM) and 13:30 (PM) of the same day. This protocol included Doppler measurements of uterine, umbilical, and fetal middle cerebral artery (MCA) volume flow parameters (flow, HR, peak systolic velocity [PSV], PI, and RI) followed by computerized cardiotocography...
December 13, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29229306/pseudo-continuous-arterial-spin-labeling-quantification-in-anemic-subjects-with-hyperemic-cerebral-blood-flow
#12
Adam Bush, Yaqiong Chai, So Young Choi, Lena Vaclavu, Scott Holland, Aart Nederveen, Thomas Coates, John Wood
PURPOSE: To investigate possible sources of quantification errors in global cerebral blood flow (CBF) measurements by comparing pseudo continuous arterial spin labeling (PCASL) and phase contrast (PC) MRI in anemic, hyperemic subjects. METHODS: All studies were performed on a Philips 3T Achieva MRI scanner. PC and PCASL CBF examinations were performed in 10 healthy, young adult subjects and 18 young adults with chronic anemia syndromes including sickle cell disease and thalassemia...
December 8, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29225580/pulsatility-of-lenticulostriate-arteries-assessed-by-7-tesla-flow-mri-measurement-reproducibility-and-applicability-to-aging-effect
#13
Roald S Schnerr, Jacobus F A Jansen, Kamil Uludag, Paul A M Hofman, Joachim E Wildberger, Robert J van Oostenbrugge, Walter H Backes
Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small lenticulostriate arteries with 7 Tesla velocity-sensitive MRI. The middle cerebral artery was included as reference. Imaging was performed in five young and five old healthy volunteers. Flow was calculated by integrating time-varying velocity values over the vascular cross-section...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29201539/assessment-of-cerebral-blood-flow-with-magnetic-resonance-imaging-in-children-with-sickle-cell-disease-a-quantitative-comparison-with-transcranial-doppler-ultrasonography
#14
Paula L Croal, Jackie Leung, Przemyslaw Kosinski, Manohar Shroff, Isaac Odame, Andrea Kassner
Introduction: Transcranial Doppler ultrasonography (TCD) is a clinical tool for stratifying ischemic stroke risk by identifying abnormal elevations in blood flow velocity (BFV) in the middle cerebral artery (MCA). However, TCD is not effective at screening for subtle neurologic injury such as silent cerebral infarcts. To better understand this disparity, we compared TCD measures of BFV with tissue-level cerebral blood flow (CBF) using arterial spin-labeling MRI in children with and without sickle cell disease, and correlated these measurements against clinical hematologic measures of disease severity...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29190150/intravenous-saline-administration-in-patients-with-severe-acquired-brain-injury-and-orthostatic-intolerance-for-tilt-table-mobilization
#15
Christian Riberholt, Niels Olesen, Peter Hovind, Jesper Mehlsen, Tue Hvass Petersen
PRIMARY OBJECTIVE: This study aimed to investigate the effect of intravenous saline administration on orthostatic hypotension (OH) during head up tilt (HUT) and the change in the renin-angiotensin-aldosterone system before and after HUT in patients with severe acquired brain injury (ABI). RESEARCH DESIGN: The study is designed as an observational study. METHODS AND PROCEDURES: Fourteen patients with ABI, low level of consciousness and OH were monitored before, during and after HUT with non-invasive beat-to-beat blood pressure measurement, and transcranial Doppler determination of middle cerebral artery blood flow velocity...
November 30, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29189269/comparison-of-transcranial-doppler-and-ultrasound-tagged-near-infrared-spectroscopy-for-measuring-relative-changes-in-cerebral-blood-flow-in-human-subjects
#16
Michael S Lipnick, Elizabeth A Cahill, John R Feiner, Philip E Bickler
BACKGROUND: Currently, no reliable method exists for continuous, noninvasive measurements of absolute cerebral blood flow (CBF). We sought to determine how changes measured by ultrasound-tagged near-infrared spectroscopy (UT-NIRS) compare with changes in CBF as measured by transcranial Doppler (TCD) in healthy volunteers during profound hypocapnia and hypercapnia. METHODS: Ten healthy volunteers were monitored with a combination of TCD, UT-NIRS (c-FLOW, Ornim Medical), as well as heart rate, blood pressure, end-tidal PCO2 (PEtCO2), end-tidal O2, and inspired O2...
November 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29187557/the-assessment-of-neurovascular-coupling-with-the-addenbrooke-s-cognitive-examination-a-functional-transcranial-doppler-ultrasonographic-study
#17
Lucy C Beishon, Claire A L Williams, Ronney B Panerai, Thompson G Robinson, Victoria Joanna Haunton
Cerebrovascular dysfunction occurs early in dementia and can be identified by Transcranial Doppler ultrasonography (TCD). Few studies have examined cerebral blood flow velocity (CBFv) responses to a detailed cognitive battery. This study aimed to characterise all CBFv responses, and the effect of hemispheric dominance, to the Addenbrooke's Cognitive Examination (ACE-III) in healthy volunteers. Forty volunteers underwent continuous bilateral TCD, beat-to-beat blood pressure (MAP) (Finapres), heart rate (HR) (electrocardiogram), and end-tidal CO2 (ETCO2) (capnography) monitoring...
November 29, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29180087/changes-in-blood-flow-velocity-of-the-middle-cerebral-artery-after-carotid-endarterectomy-daily-assessment-with-transcranial-color-coded-sonography
#18
Satoshi Koizumi, Yumiko Yamaoka, Takeshi Matsuo, Toshikazu Kimura, Tomohiro Inoue
BACKGROUND: Hyperperfusion syndrome (HPS) is a well-known complication of carotid endarterectomy (CEA) warranting repeatable inexpensive monitoring. Transcranial color-coded sonography (TCCS) may provide a potential modality for such monitoring, but little is known about TCCS trends after CEA. METHODS: Between January 2016 and February 2017, we prospectively included patients with CEA at our institute in this study. TCCS was performed preoperatively and repeated daily from the operation day until postoperative day (POD) 7...
November 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29163214/predictive-value-of-dynamic-cerebral-autoregulation-assessment-in-surgical-management-of-patients-with-high-grade-carotid-artery-stenosis
#19
Vladimir B Semenyutin, Gregory A Asaturyan, Anna A Nikiforova, Vugar A Aliev, Grigory K Panuntsev, Vadim B Iblyaminov, Alexander V Savello, Andreas Patzak
Dynamic cerebral autoregulation (DCA) capacity along with the degree of internal carotid artery (ICA) stenosis and characteristics of the plaque can also play an important role in selection of appropriate treatment strategy. This study aims to classify the patients with severe ICA stenosis according to preoperative state of DCA and to assess its dynamics after surgery. Thirty-five patients with severe ICA stenosis having different clinical type of disease underwent reconstructive surgery. DCA was assessed with transfer function analysis (TFA) by calculating phase shift (PS) between Mayer waves of blood flow velocity (BFV) and blood pressure (BP) before and after operation...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29151320/effects-of-whole-blood-viscosity-and-plasma-nox-on-cardiac-function-and-cerebral-blood-flow-in-children-with-chronic-kidney-disease
#20
Necla Buyan, Meltem Akçaboy, Tayfun Göktaş, Serdar Kula, Bijen Nazlıel, Nilgün Çakar, Nermin Uncu, Bülent Çelik, Deniz Erbaş
Background/aim: The aim of the study was to investigate the effects of whole blood viscosity and plasma nitric oxide on cerebral and cardiovascular risks associated with chronic kidney disease. Materials and methods: The study group consisted of 40 pediatric patients and 21 healthy control subjects. Hematologic and biochemical variables, viscosity and plasma nitric oxide levels, echocardiographic findings, and middle cerebral artery blood flow velocity were examined. Results: Viscosity values of patients were significantly lower than those of the control group...
November 13, 2017: Turkish Journal of Medical Sciences
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