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https://www.readbyqxmd.com/read/29161394/managing-anaesthetic-provision-for-global-disasters
#1
R M Craven
The numbers of people affected by large-scale disasters has increased in recent decades. Disasters produce a huge burden of surgical morbidity at a time when the affected country is least able to respond. For this reason an international disaster response is often required. For many years this disaster response was not coordinated. The response consisted of what was available not what was needed and standards of care varied widely producing a healthcare lottery for the affected population. In recent years the World Health organisation has initiated the Emergency Medical Team programme to coordinate the response to disasters and set minimum standards for responding teams...
December 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29159904/growing-into-teen-fatherhood-a-grounded-theory-study
#2
C Uengwongsapat, K Kantaruksa, A Klunklin, N Sansiriphun
BACKGROUND: Becoming an adolescent father is a significant and critical life event. Expectant fathers are faced with a concurrent dual developmental crisis: being an adolescent and becoming a father. This transition has a tremendous impact on these adolescents, their families and society. The impact on these individuals and society does not, at this point, seem to be clearly understood. PURPOSE: To explore the process of Thai adolescents becoming first-time fathers with an unplanned pregnancy during their girlfriend's pregnancy...
November 21, 2017: International Nursing Review
https://www.readbyqxmd.com/read/29159733/management-of-hemophilia-in-older-patients
#3
REVIEW
Massimo Franchini, Pier Mannuccio Mannucci
In recent decades, several improvements in hemophilia care have resulted in increased quality of life and life expectancy for those affected by this inherited hemorrhagic condition. Nowadays, individuals with hemophilia enjoy a life expectancy at birth close to that of males in the general population. As a consequence of the increasing age of the hemophilia population, a growing number of these patients develop age-related co-morbidities, such as cardiovascular disease and cancer, the management of which represents a new challenge for caregivers at hemophilia treatment centers...
November 20, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/29159660/opinion-paracoccidioidomycosis-and-hiv-immune-recovery-inflammatory-syndrome
#4
Renata Buccheri, Gil Benard
Two distinct patterns of immune recovery inflammatory syndrome (IRIS) are recognized, paradoxical and unmasking IRIS. Here we raise some concerns regarding the first case of neuroPCM-IRIS published to date, as recently proposed by Almeida and Roza (Mycopathologia 177:137-141, 2017) for a patient originally described by Silva-Vergara et al. (Mycopathologia 182:393-396, 2014), taking in account the different case definitions for IRIS and the cases of neuroparacoccidioidomycosis already described in the literature...
November 20, 2017: Mycopathologia
https://www.readbyqxmd.com/read/29158885/taxonomy-based-approaches-to-quality-assurance-of-ontologies
#5
Michael Halper, Yehoshua Perl, Christopher Ochs, Ling Zheng
Ontologies are important components of health information management systems. As such, the quality of their content is of paramount importance. It has been proven to be practical to develop quality assurance (QA) methodologies based on automated identification of sets of concepts expected to have higher likelihood of errors. Four kinds of such sets (called QA-sets) organized around the themes of complex and uncommonly modeled concepts are introduced. A survey of different methodologies based on these QA-sets and the results of applying them to various ontologies are presented...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29158552/care-and-cost-consequences-of-pediatric-whole-genome-sequencing-compared-to-chromosome-microarray
#6
Robin Z Hayeems, Jasmin Bhawra, Kate Tsiplova, M Stephen Meyn, Nasim Monfared, Sarah Bowdin, D James Stavropoulos, Christian R Marshall, Raveen Basran, Cheryl Shuman, Shinya Ito, Iris Cohn, Courtney Hum, Marta Girdea, Michael Brudno, Ronald D Cohn, Stephen W Scherer, Wendy J Ungar
The clinical use of whole-genome sequencing (WGS) is expected to alter pediatric medical management. The study aimed to describe the type and cost of healthcare activities following pediatric WGS compared to chromosome microarray (CMA). Healthcare activities prompted by WGS and CMA were ascertained for 101 children with developmental delay over 1 year. Activities following receipt of non-diagnostic CMA were compared to WGS diagnostic and non-diagnostic results. Activities were costed in 2016 Canadian dollars (CDN)...
November 20, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29158373/revisiting-expectations-in-an-era-of-precision-oncology
#7
Emily J Marchiano, Andrew C Birkeland, Paul L Swiecicki, Kayte Spector-Bagdady, Andrew G Shuman
As we enter an era of precision medicine and targeted therapies in the treatment of metastatic cancer, we face new challenges for patients and providers alike as we establish clear guidelines, regulations, and strategies for implementation. At the crux of this challenge is the fact that patients with advanced cancer may have disproportionate expectations of personal benefit when participating in clinical trials designed to generate generalizable knowledge. Patient and physician goals of treatment may not align, and reconciliation of their disparate perceptions must be addressed...
November 20, 2017: Oncologist
https://www.readbyqxmd.com/read/29158140/consequences-of-an-uncertain-mass-mortality-regime-triggered-by-climate-variability-on-giant-clam-population-management-in-the-pacific-ocean
#8
Simon Van Wynsberge, Serge Andréfouët, Nabila Gaertner-Mazouni, Georges Remoissenet
Despite actions to manage sustainably tropical Pacific Ocean reef fisheries, managers have faced failures and frustrations because of unpredicted mass mortality events triggered by climate variability. The consequences of these events on the long-term population dynamics of living resources need to be better understood for better management decisions. Here, we use a giant clam (Tridacna maxima) spatially explicit population model to compare the efficiency of several management strategies under various scenarios of natural mortality, including mass mortality due to climatic anomalies...
November 17, 2017: Theoretical Population Biology
https://www.readbyqxmd.com/read/29158016/genetic-hemochromatosis-pathophysiology-diagnostic-and-therapeutic-management
#9
Pierre Brissot, Thibault Cavey, Martine Ropert, Pascal Guggenbuhl, Olivier Loréal
The term hemochromatosis (HC) corresponds to several diseases characterized by systemic iron overload of genetic origin and affecting both the quality of life and life expectancy. Major improvement in the knowledge of iron metabolism permits to divide these diseases into two main pathophysiological categories. For most HC forms (types 1, 2, 3 and 4B HC) iron overload is related to cellular hepcidin deprivation which causes an increase of plasma iron concentration and the appearance of plasma non-transferrin bound iron...
November 17, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29157614/poems-syndrome-diagnosis-and-investigative-work-up
#10
REVIEW
Angela Dispenzieri, Taxiarchis Kourelis, Francis Buadi
POEMS syndrome is a rare paraneoplastic syndrome secondary to a plasma cell dyscrasia. Recognition of a combination of peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasmaproliferative disorder, skin changes, papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis, and Castleman disease is the first step in managing the disease. Increased blood levels of vascular endothelial growth factor are usually confirmatory. This rare disorder should not be missed, especially if the patient has a putative diagnosis of chronic inflammatory polyradiculoneuropathy, a lambda restricted monoclonal gammopathy, and thrombocytosis, and is not responding as expected to immunomodulatory therapy commonly used for chronic inflammatory polyradiculoneuropathy...
February 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29157400/advanced-symptom-management-in-multiple-sclerosis
#11
REVIEW
Elizabeth Crabtree-Hartman
Meaningful symptom management can have a profound impact on quality of life. It can challenge time parameters during clinic, and therefore thought should be given to strategies that can improve efficiency and thereby make the undertaking more tenable. For any given symptom, the building blocks of care, such as vitamin D status, exercise/physical therapy, nutrition, and stress management, and ensuring disease-modifying therapy coverage, should be maximized. For each symptom, there are pharmacologic and nonpharmacologic interventions...
February 2018: Neurologic Clinics
https://www.readbyqxmd.com/read/29157369/risk-factors-associated-with-the-a2c-resistance-pattern-among-e-coli-isolates-from-broiler-flocks-in-canada
#12
Niamh Caffrey, Omid Nekouei, Sheryl Gow, Agnes Agunos, Sylvia Checkley
The extra-label use of ceftiofur in Canadian hatcheries was cause for concern due to an increased prevalence of ceftiofur resistant Salmonella Heidelberg in chickens and humans in Québec. Due to on-going concerns related to human health the use of ceftiofur was eventually phased out of the poultry production industry in 2014-2015. Simultaneous resistance to amoxicillin-clavulanic acid, ceftiofur and cefoxitin, a pattern known as A2C, caused by the presence of blaCMY-2 has become increasingly prevalent in broiler flocks worldwide...
December 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29157366/culling-from-the-actors-perspectives-decision-making-criteria-for-culling-in-qu%C3%A3-bec-dairy-herds-enrolled-in-a-veterinary-preventive-medicine-program
#13
Denis Haine, Roger Cue, Asheber Sewalem, Kevin Wade, René Lacroix, Daniel Lefebvre, Jonathan Rushton, Julie Arsenault, Émile Bouchard, Jocelyn Dubuc
The series of events leading to the decision to cull a cow is complex, involving both individual-level and herd-level factors. While the decision is guided by financial returns, it is also influenced by social and psychological factors. Research studies on the motivational and behavioural aspects of farmers' decision utility are sparse, and nonexistent regarding culling expectations and its decision process. Our goal was to identify shared criteria on culling decisions held by dairy producers and farm advisers, with the help of the Q-methodology...
December 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29156331/may-humic-acids-or-mineral-fertilisation-mitigate-arsenic-mobility-and-availability-to-carrot-plants-daucus-carota-l-in-a-volcanic-soil-polluted-by-as-from-irrigation-water
#14
Antonio G Caporale, Paola Adamo, Shah M G G Azam, Maria A Rao, Massimo Pigna
Carrot (Daucus carota L.) is a widely consumed root vegetable, whose growth and safety might be threatened by growing-medium arsenic (As) contamination. By this work, we evaluated the effects of humic acids from Leonardite and NPK mineral fertilisation on As mobility and availability to carrot plants grown for 60 days in a volcanic soil irrigated with As-contaminated water - representing the most common scenario occurring in As-affected Italian areas. As expected, the irrigation with As-contaminated water caused a serious toxic effect on plant growth and photosynthetic rate; the highest rate of As also inhibited soil enzymatic activity...
November 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/29156266/seabirds-as-regional-biomonitors-of-legacy-toxicants-on-an-urbanized-coastline
#15
Corey A Clatterbuck, Rebecca L Lewison, Nathan G Dodder, Catherine Zeeman, Kenneth Schiff
Seabirds are often cited as sentinels of the marine environment, but are rarely used in traditional ocean and coastal contaminant monitoring. Four classes of persistent organic pollutants (POPs, n=68) and three trace elements (mercury, selenium, and arsenic) were measured in the eggs of California least terns (Sterna antillarum browni), caspian terns (Hydroprogne caspia), double-crested cormorants (Phalacrocorax auritus), and western gulls (Larus occidentalis) that nest in the Southern California Bight. Building on a periodic five year regional monitoring program, we measured contaminant exposure and assessed the utility of seabirds as regional contaminant biomonitors...
November 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29156232/use-of-negative-pressure-wound-therapy-after-infection-and-flap-dehiscence-in-radical-vulvectomy-a-case-report
#16
Antoni Llueca, Jose Luis Herraiz, Raquel Del Moral, Dolors Piquer, Yasmine Maazouzi, Blanca Segarra, Jordan Barres, Anna Serra
INTRODUCTION: Vulvar cancer has a lower incidence in high income countries, but is rising, in part, due to the high life expectancy in these societies. Radical vulvectomy is still the standard treatment in initial stages. Wound dehiscence contitututes one of the most common postoperative complications. PRESENTATION OF CASE: A 76year old patient with a squamous cell carcinoma of the vulva, FIGO staged, IIIb is presented. Radical vulvectomy and bilateral inguinal lymph node dissection with lotus petal flaps reconstruction are performed as the first treatment...
November 6, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29155531/a-review-of-the-available-guidance-regarding-management-of-medical-emergencies-in-primary-dental-care
#17
Suzanne Lello, Julie Burke, Kathryn Taylor
This article provides an overview of the recent changes in guidance relating to the management of medical emergencies in primary dental care in the UK. The guidance relating to automated external defibrillators is also presented. The expectations of our regulatory bodies are discussed, as are the requirements for continued professional development. The potential shortcomings of the changes to the guidance are also discussed, as well as proposed solutions, such as the development of algorithms to use in a dental practice setting...
December 2016: Dental Update
https://www.readbyqxmd.com/read/29155502/elderly-patients-with-glomerular-diseases-and-iga-nephropathy
#18
REVIEW
Jing Lin, Zhen Cheng, Qi Qian
As the population ages, greater numbers of elderly patients will present with kidney diseases. Many kidney diseases, such as IgA nephropathy, will require kidney biopsy for diagnostic confirmation, treatment guidance and prognostication. In this paper, we review the current and expected future healthcare landscape with a focus on the ageing population, pros and cons of kidney biopsy in elderly patients, as well as treatment strategies and precautions. We also review the available data on IgA nephropathy in the elderly, including its occurrence rate based on the kidney biopsy, clinicohistopathological features, differentiation with IgA-dominant postinfectious glomerulonephritis, treatment options and outcome prediction...
December 2017: Nephrology
https://www.readbyqxmd.com/read/29155342/predictors-before-and-after-multimodal-rehabilitation-for-pain-acceptance-and-engagement-in-activities-at-a-one-year-follow-up-for-patients-with-whiplash-associated-disorders-wad-a-study-based-on-the-swedish-quality-registry-for-pain-rehabilitation-sqrp
#19
Anne Söderlund, Monika Löfgren, Britt-Marie Stålnacke
BACKGROUND: Studies have shown that pain acceptance strategies related to psychological flexibility are important in the presence of chronic musculoskeletal pain. However, the predictors of these strategies have not been studied extensively in patients with Whiplash Associated Disorders (WAD). PURPOSE: The purpose of this study was to predict chronic pain acceptance and engagement in activities at one-year follow-up with pain intensity, fear of movement, perceived responses from significant others, outcome expectancies, and demographic variables in patients with WAD before and after multimodal rehabilitation (MMR)...
November 16, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29155253/the-association-of-inflammatory-bowel-disease-and-immediate-postoperative-outcomes-following-lumbar-fusion
#20
Joseph E Tanenbaum, Stephanie T Kha, Edward C Benzel, Michael P Steinmetz, Thomas E Mroz
BACKGROUND CONTEXT: The United States Centers for Disease Control estimates the prevalence of inflammatory bowel disease (IBD) at over 3.1 million people. As diagnostic techniques and treatment options for IBD improve, the prevalence of IBD is expected to increase. For spine surgeons, patients with IBD have a unique complication profile because IBD patients may present with poor nutritional status and because the medications used to manage IBD have been associated with poor vertebral bone mineralization and immunosuppression...
November 15, 2017: Spine Journal: Official Journal of the North American Spine Society
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