keyword
MENU ▼
Read by QxMD icon Read
search

Energy medicine

keyword
https://www.readbyqxmd.com/read/28323877/thermal-analysis-during-partial-carbonizing-process-of-rhubarb-moutan-and-burnet
#1
Junnan Ma, Xianglong Meng, Xiaohui Guo, Yaru Lan, Shuosheng Zhang
Control of temperature and duration of partial carbonization for Chinese medicines have been mainly based on experience of the processors. No quantitative methods and parameters are available that can be used to precisely control the temperature and determine the energy changes during the process. In our research, with a simulated atmosphere air condition, the partial carbonization processes of three Chinese herb medicines rhubarb, moutan and burnet were simulated at different heating rates (5, 10 and 20°C • min-1) and analyzed by thermal gravimetric analysis (TGA) to quantify the upper limits of the temperature...
2017: PloS One
https://www.readbyqxmd.com/read/28323803/patient-response-to-an-integrated-orthotic-and-rehabilitation-initiative-for-traumatic-injuries-the-prioriti-mtf-study
#2
Joseph R Hsu, Johnny G Owens, Jennifer DeSanto, John R Fergason, Kevin M Kuhn, Benjamin K Potter, Daniel J Stinner, Robert G Sheu, Sandra L Waggoner, Jason M Wilken, Yanjie Huang, Daniel O Scharfstein, Ellen J MacKenzie
Although limb salvage is now possible for many high-energy open fractures and crush injuries to the distal tibia, ankle, hindfoot, and midfoot, orthotic options are limited. The Intrepid Dynamic Exoskeletal Orthosis (IDEO) is a custom, energy-storing carbon fiber orthosis developed for trauma patients undergoing limb salvage. The IDEO differs from other orthoses in that it allows patients with ankle weakness to have more normal ankle biomechanics and increased ankle power. This article describes the design of a study to evaluate the effectiveness of the IDEO when delivered together with a high-intensity, sports medicine-based approach to rehabilitation...
April 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28297600/a-high-throughput-survey-of-ordering-configurations-in-mxene-alloys-across-compositions-and-temperatures
#3
Teck Leong Tan, Hong Mei Jin, Michael Brian Sullivan, Babak Anasori, Yury Gogotsi
2D transition metal carbides and nitrides known as MXenes are gaining increasing attention. About 20 of them have been synthesized (more predicted) and their applications in fields ranging from energy storage and electromagnetic shielding to medicine are being explored. To facilitate the search for new double-transition-metal MXenes, we explore the structure-stability relationship for 8 MXene alloy systems, namely, (V1-xMox)3C2, (Nb1-xMox)3C2, (Ta1-xMox)3C2, (Ti1-xMox)3C2, (Ti1-xNbx)3C2, (Ti1-xTax)3C2, (Ti1-xVx)3C2 and (Nb1-xVx)3C2,¬ with 0 ≤ x ≤ 1, using high-throughput computations...
March 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28297310/production-and-quality-control-177-lu-nca-dotmp-as-a-potential-agent-for-bone-pain-palliation
#4
Nafise Salek, Mojtaba Shamsaei, Mohammad Ghannadi Maragheh, Simindokht Shirvani Arani, Ali Bahrami Samani
Skeletal uptake of radiolabeled-1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetramethylene phosphoric acid (e.g., (177) Lu-DOTMP) complex, is used for bone pain palliation. The moderate energy of β-emitting 177Lu (T1/2=6.7 d,Eβmax=497 keV) has been considered as a potential radionuclide for development of the bone-seeking radiopharmaceutical. Since the specific activity of the radiolabeled carrier molecules should be high, the "no-carrier-added radionuclides" have significant roles in nuclear medicine...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28295935/real-time-in%C3%A2-vivo-hepatotoxicity-monitoring-through-chromophore-conjugated-photon-upconverting-nanoprobes
#5
Juanjuan Peng, Animesh Samanta, Xiao Zeng, Sanyang Han, Lu Wang, Dongdong Su, Daniel Teh Boon Loong, Nam-Young Kang, Sung-Jin Park, Angelo Homayoun All, Wenxuan Jiang, Lin Yuan, Xiaogang Liu, Young-Tae Chang
Drug toxicity is a long-standing concern of modern medicine. A typical anti-pain/fever drug paracetamol often causes hepatotoxicity due to peroxynitrite ONOO(-) . Conventional blood tests fail to offer real-time unambiguous visualization of such hepatotoxicity in vivo. Here we report a luminescent approach to evaluate acute hepatotoxicity in vivo by chromophore-conjugated upconversion nanoparticles. Upon injection, these nanoprobes mainly accumulate in the liver and the luminescence of nanoparticles remains suppressed owing to energy transfer to the chromophore...
March 15, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28291684/identification-of-compounds-with-cytotoxic-activity-from-the-leaf-of-the-nigerian-medicinal-plant-anacardium-occidentale-l-anacardiaceae
#6
Bamigboye J Taiwo, Amos A Fatokun, Olujide O Olubiyi, Olukemi T Bamigboye-Taiwo, Fanie R van Heerden, Colin W Wright
Cancer is now the second-leading cause of mortality and morbidity, behind only heart disease, necessitating urgent development of (chemo)therapeutic interventions to stem the growing burden of cancer cases and cancer death. Plants represent a credible source of promising drug leads in this regard, with a long history of proven use in the indigenous treatment of cancer. This study therefore investigated Anacardium occidentale, one of the plants in a Nigerian Traditional Medicine formulation commonly used to manage cancerous diseases, for cytotoxic activity...
February 22, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28290868/-is-it-possible-to-improve-results-in-the-conservative-treatment-strategy-in-patients-with-acute-coronary-syndrome
#7
M G Gleser, E I Astashkin, A E Kiseleva
Almost 60% of patients with acute coronary syndrome (ACS) without ST segment elevation are not subjected to revascularization procedures. This review analyzes the reasons for the choice of the conservative tactics of patients with ACS. The possibilities of improving outcomes by using modern medicines. Particular attention is given to drugs that affect energy metabolism in cardiomyocytes ischemia and reperfusion, provides data on the effect of L-carnitine on the high-risk markers, and decrease the incidence of adverse outcomes in patients with ACS...
September 2016: Kardiologiia
https://www.readbyqxmd.com/read/28287264/prospective-evaluation-of-free-energy-calculations-for-the-prioritization-of-cathepsin-l-inhibitors
#8
Bernd Kuhn, Michal Tichý, Lingle Wang, Shaughnessy Robinson, Rainer E Martin, Andreas Kuglstatter, Jörg Benz, Maude Giroud, Tanja Schirmeister, Robert Abel, François Diederich, Jérôme Hert
Improving the binding affinity of a chemical series by systematically probing one of its exit vectors is a medicinal chemistry activity that can benefit from molecular modeling input. Herein, we compare the effectiveness of four approaches in prioritizing building blocks with better potency: selection by a medicinal chemist, manual modeling, docking followed by manual filtering, and free energy calculations (FEP). Our study focused on identifying novel substituents for the apolar S2 pocket of cathepsin L and was conducted entirely in a prospective manner with synthesis and activity determination of 36 novel compounds...
March 13, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28278765/antimycobacterial-docking-and-molecular-dynamic-studies-of-pentacyclic-triterpenes-from-buddleja-saligna-leaves
#9
Alveera Singh, Katharigatta N Venugopala, Mohammed A Khedr, Mellendran Pillay, Kenneth U Nwaeze, Yacoob Coovadia, Francis Shode, Bharti Odhav
Buddleja saligna (family Buddlejaceae) is a medicinal plant endemic to South Africa. Two isomeric pentacyclic triterpenes, oleanolic acid and ursolic acid, were isolated from the leaves of B. saligna using silica gel column chromatography. Compounds oleanolic acid and ursolic acid were subjected to derivatization with acetic anhydride in the presence of pyridine to obtain oleanolic acid-3-acetate and ursolic acid-3-acetate, respectively. The structures of these compounds were fully characterized by detailed nuclear magnetic resonance (NMR) investigations, which included (1)H and (13)C NMR...
September 22, 2016: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28276611/transition-metal-catalyzed-utilization-of-methanol-as-c1-source-in-organic-synthesis
#10
Jagadeesh Rajenahally, Kishore Natte, Helfried Neumann, Matthias Beller
Methanol represents one of the privileged and widespread platform chemicals, which is used in many science sectors such as chemistry, biology, medicine and energy. This essential alcohol serves as common solvent, cost-effective reagent and sustainable feedstock for value-added chemicals, pharmaceuticals and materials. Among different applications, the utilization of methanol as C1 source for the formation of carbon-carbon, carbon-nitrogen and carbon-oxygen bonds continues to be important in organic synthesis and drug discovery...
March 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28275047/the-new-biology-and-pharmacology-of-glucagon
#11
REVIEW
T D Müller, B Finan, C Clemmensen, R D DiMarchi, M H Tschöp
In the last two decades we have witnessed sizable progress in defining the role of gastrointestinal signals in the control of glucose and energy homeostasis. Specifically, the molecular basis of the huge metabolic benefits in bariatric surgery is emerging while novel incretin-based medicines based on endogenous hormones such as glucagon-like peptide 1 and pancreas-derived amylin are improving diabetes management. These and related developments have fostered the discovery of novel insights into endocrine control of systemic metabolism, and in particular a deeper understanding of the importance of communication across vital organs, and specifically the gut-brain-pancreas-liver network...
April 2017: Physiological Reviews
https://www.readbyqxmd.com/read/28274222/knowledge-attitudes-and-practices-among-health-care-providers-regarding-complementary-and-alternative-medicine-in-trinidad-and-tobago
#12
Mandreker Bahall, George Legall
BACKGROUND: Health care providers are often ill prepared to interact about or make acceptable conclusions on complementary and alternative medicine (CAM) despite its widespread use. We explored the knowledge, attitudes, and practices of health care providers regarding CAM. METHODS: This cross-sectional study was conducted between March 1 and July 31, 2015 among health care providers working mainly in the public sector in Trinidad and Tobago. A 34-item questionnaire was distributed and used for data collection...
March 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28274170/protective-effects-of-cassia-tora-leaves-in-experimental-cataract-by-modulating-intracellular-communication-membrane-co-transporters-energy-metabolism-and-the-ubiquitin-proteasome-pathway
#13
V Sreelakshmi, Annie Abraham
CONTEXT: Cataract is the clouding of eye lens which causes impairment in vision and accounts for the leading factor of global blindness. Functional food-based prevention of cataract finds application in vision research because of its availability and easy access to all classes of the society. Cassia tora Linn. (Caesalpinaceae) is an edible plant mentioned in the traditional systems of medicine for whole body health, especially to the eyes. OBJECTIVE: The present study evaluates the potential of ethyl acetate fraction of Cassia tora leaves (ECT) on experimental cataract...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28271444/the-role-of-mitochondria-in-osteogenic-adipogenic-and-chondrogenic-differentiation-of-mesenchymal-stem-cells
#14
REVIEW
Qianqian Li, Zewen Gao, Ye Chen, Min-Xin Guan
Mesenchymal stem cells (MSCs) are progenitors of connective tissues, which have emerged as important tools for tissue engineering due to their differentiation potential along various cell types. In recent years, accumulating evidence has suggested that the regulation of mitochondria dynamics and function is essential for successful differentiation of MSCs. In this paper, we review and provide an integrated view on the role of mitochondria in MSC differentiation. The mitochondria are maintained at a relatively low activity level in MSCs, and upon induction, mtDNA copy number, protein levels of respiratory enzymes, the oxygen consumption rate, mRNA levels of mitochondrial biogenesis-associated genes, and intracellular ATP content are increased...
March 7, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28269994/holmium-yag-laser-and-guidewires-is-there-a-durability-difference-among-guidewires-against-laser-energy-an-in-vitro-experimental-study
#15
Sahin Bagbanci
Purpose To evaluate the durability differences between five different type of guidewire against laser energy in an in-vitro experimental ureteral model. Methods The study was performed at the Department of Urology, Medicine Faculty of Ahi Evran University. An in-vitro experimental ureteral model was created for the work; a silicon ureteral model in a saline filled container. Experiments were performed on five different type of guidewire; ZIPwire, Sensor PTFE Nitinol guidewire, Roadrunner® PC wire guide, Amplatz Super Stiff and Zebra Urologic Guidewire...
March 7, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28268376/micro-tube-mass-production-device-for-microbial-culture
#16
K Fujimoto, M Ogawa, K Higashi, N Miki
This paper describes mass production system of micro-tubes for microbial culture in an open environment. Microbes are used in many fields, such as food, medicine, environmental and energy. We proposed a microbe culture system using hydrogel micro-tubes, which can protect the target microbes inside from competitive microbes outside of the tubes while allow oxygen and nutrition to diffuse through. The hydrogel micro-tubes can be produced by a microfluidic device, which can precisely control the flow and therefore, the tube geometry...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268173/improvement-of-osteoporosis-by-lycium-chinense-administration-in-ovariectomized-mice
#17
Mi Hye Kim, Ji Eun Lee, Jae Sung Lee, Woong Mo Yang
BACKGROUND: The fruit of Lycium chinense (LC), one of the most popular natural materials, has been used to counter the effects of musculoskeletal diseases in oriental medicine. In particular, this fruit is known to have antiaging effects, which is of significant interest to the research community. The purpose of our investigation was to observe and confirm the ameliorative effect of LC on osteoporosis, which was verified in this in vivo study. METHODS: Female ICR mice aged 5 weeks were surgically ovariectomized (OVX) to induce osteoporosis...
March 3, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28265542/the-effect-of-hydro-alcoholic-extract-of-achillea-millefolium-on-appetite-hormone-in-rats
#18
Mohsen Nematy, Mohsen Mazidi, Atefeh Jafari, Sara Baghban, Hasan Rakhshandeh, Abdolreza Norouzy, Habibollah Esmaily, Leila Etemad, Michael Patterson, Amir Hooshang Mohammadpour
OBJECTIVE: Achillea millefolium (A. millefolium) is known as an orexigenic herb in Iranian traditional medicine. In this study, the possible orexigenic effect of hydro-alcoholic extract of A. millefolium was investigated by measuring plasmaghrelin level. MATERIALS AND METHODS: Thirty male Wistar rats were divided into five groups. Control group received water. Treatment groups received 50, 100 or 150 mg/kg of A. millefolium extract for 7 days via gavage. Before the intervention, daily amount of the food eaten by each rat was measured for 10 days...
January 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28261474/expression-of-fatty-acid-sensing-g-protein-coupled-receptors-in-peripartal-holstein-cows
#19
Alea Agrawal, Abdulrahman Alharthi, Mario Vailati-Riboni, Zheng Zhou, Juan J Loor
BACKGROUND: G-protein coupled receptors (GPCR), also referred as Free Fatty Acid Receptors (FFAR), are widely studied within human medicine as drug targets for metabolic disorders. To combat metabolic disorders prevalent in dairy cows during the transition period, which co-occur with negative energy balance and changes to lipid and glucose metabolism, it may be helpful to identify locations and roles of FFAR and other members of the GPCR family in bovine tissues. RESULTS: Quantitative RT-PCR (qPCR) of subcutaneous adipose, liver, and PMNL samples during the transition period (-10, +7, and +20 or +30 d) were used for expression profiling of medium- (MCFA) and long-chain fatty acid (LCFA) receptors GPR120 and GPR40, MCFA receptor GPR84, and niacin receptor HCAR2/3...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28259893/evaluation-of-6-chloro-n-3-4-disubstituted-1-3-thiazol-2-3h-ylidene-1-3-benzothiazol-2-amine-using-drug-design-concept-for-their-targeted-activity-against-colon-cancer-cell-lines-hct-116-hct15-and-ht29
#20
Ming-Li Zhu, Cui-Yue Wang, Cheng-Mian Xu, Wei-Ping Bi, Xiu-Ying ZHou
BACKGROUND Colorectal adenocarcinoma is the second leading cause of cancer-related death in the world. The stage of the disease is related to the survival of the patient, and in early phases surgery is the main modality of treatment. The main aim of modern medicinal chemistry is to synthesize small molecules via drug designing, especially by targeting tumor cells. MATERIAL AND METHODS A new series of 19 compounds containing benzothiazole and thiazole were designed. Molecular docking studies were performed on the designed series of molecules...
March 5, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
keyword
keyword
79741
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"