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https://www.readbyqxmd.com/read/29663469/quantitative-ultrasound-analysis-of-proximal-and-distal-cervical-tissue-echogenicity-in-premature-cervical-remodeling
#1
Matthew J Blitz, Sleiman R Ghorayeb, Sarah L Pachtman, Megan Murphy, Zara Rahman, Lakha Prasannan, Cristina P Sison, Nidhi Vohra, Burton Rochelson
OBJECTIVES: To determine whether a novel, noninvasive quantitative ultrasound (US) technique can detect differences in proximal and distal cervical tissue echogenicity in women with and without a shortened cervical length (CL). METHODS: We conducted a retrospective case-control study of singleton pregnancies at 16 to 26 weeks' gestation in which a transvaginal US examination was performed to measure CL from 2013 to 2015. Initial CLs in cases and controls were less than 2...
April 16, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29575422/differentiated-cervical-intraepithelial-neoplasia-associated-invasive-cervical-squamous-cell-carcinoma-as-a-source-of-major-cytopathological-and-surgical-pathological-discrepancy-in-papanicolaou-smear-screening-tests
#2
K T Mai
INTRODUCTION: Differentiated cervical intraepithelial neoplasia (dCIN) analogous to differentiated squamous intraepithelial neoplasia of the vulva is characterised by the proliferation of atypical cells limited to the basal/parabasal layers. Exfoliative cytology of dCIN has not been investigated. METHODS AND RESULTS: A 46-year-old woman, with a history of normal Papanicolaou (Pap) smear up to 2 years prior to the occurrence of postcoital vaginal bleeding had two consecutive Pap smears, which only revealed atypical squamous cells of unknown significance (ASCUS)...
April 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29574908/ppar%C3%AE-plays-dual-roles-on-experimental-periodontitis-in-rats
#3
Weiwei Qiao, Changning Wang, Wushuang Huang, Yingying Hu, Yaling Song
AIM: To investigate the effects of PPARγ on inflammation control and bone remodeling in experimental periodontitis in rats. MATERIALS AND METHODS: Experimental periodontitis was induced in rats by thread ligation around cervixes of mandibular first molars. PPARγ agonist, antagonist and vehicle were intraperitoneally administrated respectively into rats. 96 male SD rats were randomly divided into control, ligation+vehicle, ligation+agonist and ligation+antagonist groups...
March 25, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29560285/mid-trimester-cervical-consistency-index-and-cervical-length-to-predict-spontaneous-preterm-birth-in-a-high-risk-population
#4
Núria Baños, Carla Julià, Núria Lorente, Silvia Ferrero, Teresa Cobo, Eduard Gratacos, Montse Palacio
Background  Short cervical length (CL) has not been shown to be adequate as a single predictor of spontaneous preterm birth (sPTB) in high-risk pregnancies. Objective  The objective of this study was to evaluate the performance of the mid-trimester cervical consistency index (CCI) to predict sPTB in a cohort of high-risk pregnancies and to compare the results with those obtained with the CL. Study Design  Prospective cohort study including high-risk singleton pregnancies between 19 +0 and 24 +6 weeks...
January 2018: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29468770/pessary-for-prevention-of-preterm-birth-in-twin-pregnancy-with-short-cervix-3-year-follow-up-study
#5
J van 't Hooft, J H van der Lee, B C Opmeer, A G van Wassenaer-Leemhuis, A L van Baar, D J Bekedam, L J P Steenis, S Liem, E Schuit, C Cuijpers, E Bleeker, M E Vinke, N Simons, I M de Graaf, B W J Mol, C van de Beek
OBJECTIVE: A recent randomized clinical trial (ProTWIN) showed that a cervical pessary prevented preterm birth and improved neonatal outcome in women with multiple pregnancy and cervical length (CL) < 38 mm. In this follow-up study, the long-term developmental outcome of these children was evaluated at 3 years' corrected age. METHODS: This was a follow-up study of ProTWIN, a multicenter trial conducted between 2009 and 2012 in which asymptomatic women with a multiple pregnancy were randomized to placement of a cervical pessary or no intervention...
February 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29461973/mid-pregnancy-cervical-length-as-a-risk-factor-for-cesarean-section-in-women-with-twin-pregnancies
#6
Su Jin Sung, Seung Mi Lee, Sohee Oh, Joo Hee Choi, Jee Yoon Park, Byoung Jae Kim, Joon Ho Lee, Chan-Wook Park, Joong Shin Park, Jong Kwan Jun
OBJECTIVE: It is well known that a short cervix at mid-pregnancy is a risk factor for spontaneous preterm birth in both singleton and twin gestations. Recent evidence also suggests that a long cervix at mid-pregnancy is a predictor of the risk of cesarean section (C/S) in singleton gestation. The purpose of this study was to determine whether a long cervix at mid-pregnancy was associated with an increased risk of C/S in women with twin pregnancies. METHODS: We enrolled 746 women pregnant with twins whose cervical length was measured by trans-vaginal ultrasonography at a mean of 22 weeks of gestation and who delivered in our institution...
February 20, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29455036/short-term-post-operative-morphing-of-sacrocolpopexy-mesh-measured-by-magnetic-resonance-imaging
#7
Nikhil Sindhwani, Geertje Callewaert, Thomas Deprest, Susanne Housmans, Dirk Van Beckevoort, Jan Deprest
BACKGROUND: Sacrocolpopexy (SC) involves suspension of the vaginal vault or cervix to the sacrum using a mesh. Following insertion, the meshes have been observed to have undergone dimensional changes. OBJECTIVE: To quantify dimensional changes of meshes following implantation and characterize their morphology in-vivo. DESIGN SETTING AND PARTICIPANTS: 24 patients underwent SC using PolyVinyliDeneFluoride mesh loaded with Fe3 O4 particles. Tailored anterior and posterior mesh flaps were sutured to the respective vaginal walls, uniting at the apex...
February 11, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29447720/no-257-ultrasonographic-cervical-length-assessment-in-predicting-preterm-birth-in-singleton-pregnancies
#8
Kenneth Lim, Kimberly Butt, Joan M Crane
OBJECTIVES: To review (1) the use of ultrasonographic-derived cervical length measurement in predicting preterm birth and (2) interventions associated with a short cervical length. OUTCOMES: Reduction in rates of prematurity and/or better identification of those at risk, as well as possible prevention of unnecessary interventions. EVIDENCE: Published literature was retrieved through searches of PubMed and The Cochrane Library up to December 2009, using appropriate controlled vocabulary and key words (preterm labour, ultrasound, cervix, incompetent cervix, transvaginal, transperineal, cervical length, fibronectin)...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29431861/non-steroidal-anti-inflammatory-agents-to-induce-regression-and-prevent-the-progression-of-cervical-intraepithelial-neoplasia
#9
REVIEW
Shannon M Grabosch, Osman M Shariff, C William Helm
BACKGROUND: This is an updated version of the original Cochrane review published in 2014, Issue 4. Cervical intraepithelial neoplasia (CIN) precedes the development of invasive carcinoma of the cervix. Current treatment of CIN is quite effective, but there is morbidity for the patient related to pain, bleeding, infection, cervical stenosis and premature birth in a subsequent pregnancy. Effective treatment with medications, rather than surgery, would be beneficial. OBJECTIVES: To evaluate the effectiveness and safety of non-steroidal anti-inflammatory agents (NSAIDs), including cyclooxygenase-2 (COX-2) inhibitors, to induce regression and prevent the progression of CIN...
February 12, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29422255/prevention-of-spontaneous-preterm-birth-universal-cervical-length-assessment-and-vaginal-progesterone-in-women-with-a-short-cervix-time-for-action
#10
EDITORIAL
Stuart Campbell
No abstract text is available yet for this article.
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29414522/don-t-be-short-sighted-cervical-incompetence-in-a-pregnant-patient-with-acute-appendicitis
#11
Lindsey M Negrete, Lucy B Spalluto
Delay in diagnosis of cervical incompetence can be detrimental to the fetus. Up to 20-25% of miscarriages in the second trimester can be attributed to the incompetent cervix. Given the profound impact of cervical incompetence on obstetric outcomes, careful attention should be given to evaluation of the cervix on MRI studies in pregnant patients. We present a case of incompetent cervix diagnosed incidentally at the time of MRI performed to evaluate for acute appendicitis.
January 31, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29407363/society-of-family-planning-clinical-guidelines-pain-control-in-surgical-abortion-part-1-local-anesthesia-and-minimal-sedation
#12
REVIEW
Rebecca H Allen, Rameet Singh
Satisfactory pain control for women undergoing surgical abortion is important for patient comfort and satisfaction. Clinicians ought to be aware of the safety and efficacy of different pain control regimens. This document will focus on nonpharmacologic modalities to reduce pain and pharmacologic interventions up to the level of minimal sedation. For surgical abortion without intravenous medications, a multimodal approach to pain control may combine a dedicated emotional-support person, visual or auditory distraction, administration of local anesthesia to the cervix with buffered lidocaine, and a preoperative nonsteroidal anti-inflammatory drug...
January 30, 2018: Contraception
https://www.readbyqxmd.com/read/29374983/management-of-twin-twin-transfusion-syndrome-with-an-extremely-short-cervix
#13
Myrna S Aboudiab, Andrew H Chon, Lisa M Korst, Arlyn Llanes, Joseph G Ouzounian, Ramen H Chmait
The objective of this study was to describe the management and perinatal outcomes of patients with twin-twin transfusion syndrome (TTTS) and an extremely short cervical length (CL). This retrospective study examined 17 patients with TTTS and a preoperative CL ≤1.0 cm who had undergone laser surgery and perioperative cervical cerclage placement successfully. In this subset of patients, the median interval between surgery and delivery was 9.6 (range 2.1-13.9) weeks and only one patient had PPROM within 3 weeks of surgery...
January 27, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29374885/-clinical-outcome-of-therapeutic-cervical-cerclage-in-short-cervix-syndrome
#14
H L Wang, Z Yang, Y Shen, Q L Wang
Objective: To investigate the clinical effect of therapeutic cervical cerclage on short cervix syndrome for anti-premature birth in the second trimester. Methods: Totally 44 singleton pregnant patients were diagnosed as short cervix syndrome, which was cervical length ≤2.5 cm without cervical dilatation, and received treatment from January 2008 and July 2015 in Peking University Third Hospital were collected. Among them, 30 patients who received therapeutic cervical cerclage were defined as cerclage group and another 14 cases who received conservative treatment were defined as un-cerclage group...
January 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29369475/do-fertile-women-have-an-inferior-treatment-for-high-grade-precancerous-lesions
#15
Miseon Kim, Hye-Yon Cho, Jaeil Lee, Dong Hoon Suh, Kidong Kim, Jae Hong No, Yong Beom Kim
AIM: To investigate whether a concern for future pregnancy is reflected in the extent of large loop excision of the transformation zone (LLETZ) and to assess the clinical outcome. METHODS: We reviewed the medical records of 275 women who underwent LLETZ for precancerous lesions in cervix. We divided them into two groups according to pregnancy possibility in the future: nonpotential versus potential group. The potential group was arbitrarily defined as women who met one of the following: (i) regardless of marital status, younger than 41 years with less than two parities and (ii) regardless of parity, younger than 46 years and unmarried...
January 25, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29363371/the-impact-of-cerclage-in-twin-pregnancies-on-preterm-birth-rate-before-32-weeks
#16
Michelle N Han, Betsy E O'Donnell, Melanie M Maykin, Juan M Gonzalez, Khalil Tabsh, Stephanie L Gaw
PURPOSE: To evaluate whether cerclage in twins reduces the rate of spontaneous preterm birth <32 weeks when compared to expectant management. METHODS: This is a retrospective cohort study of twin pregnancies with the following indications for cerclage from two institutions: history of prior preterm birth, ultrasound-identified short cervix ≤2.5 cm, and cervical dilation ≥1.0 cm. The "cerclage" cohort received a cerclage from a single provider at a single institution from 2003-2016...
January 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29359610/effectiveness-of-a-bipolar-vessel-sealant-device-for-ovariohysterectomy-in-cats-with-pyometra
#17
Jean-François Boursier, Jean Bassanino, Dimitri Leperlier
Objectives The objective was to describe the use of a bipolar vessel sealant device for complete ovariohysterectomy in cats - both the ovarian pedicle and the uterine body and vessels - and to report on the feasibility of ovariohysterectomy in cats with pyometra. Methods Cats with confirmed pyometra and whose owners agreed to the surgical procedure were prospectively included in the study. Ovaries were visualised and the vessel sealant device was used to coagulate and cut the suspensory ligament, the ovarian pedicle and the broad ligament up to the level of the uterine body...
January 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29359499/laparoscopic-transabdominal-cerclage-outcomes-of-121-pregnancies
#18
Alex Ades, Sneha Parghi, Mehrnoosh Aref-Adib
BACKGROUND: Cervical insufficiency is a significant cause of morbidity and mortality. Cervical cerclage is one option in the management of cervical insufficiency. AIM: To evaluate obstetric outcomes following insertion of a pre-pregnancy laparoscopic transabdominal cerclage in women at high risk for pre-term labour and/or mid-trimester pregnancy loss. METHODS: A prospective observational study of consecutive women who underwent laparoscopic transabdominal cerclage from 2007 to 2017...
January 23, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29307708/what-interventions-are-being-used-to-prevent-preterm-birth-and-when
#19
Yu Yang Feng, Alexander Jarde, Ye Rin Seo, Anne Powell, Nwachukwu Nwebube, Sarah D McDonald
OBJECTIVE: This study sought to determine the proportions of women at risk of preterm birth who received progesterone, elective and rescue cerclage, or pessary to prevent preterm birth, by using medical records. The authors also sought to determine whether these proportions differed among primary-, secondary-, and tertiary-level centres. METHODS: The authors conducted a retrospective cohort study and extracted data from consecutive medical charts of women with an estimated date of confinement over 3 months in primary-, secondary-, and tertiary-level centres in Southern Ontario...
January 4, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29239064/case-of-rapidly-progressing-condylomatous-squamous-cell-carcinoma-of-the-uterine-cervix-associated-with-low-risk-human-papillomavirus-type-6
#20
Miho Masuda, Kaoru Abiko, Sachiko Minamiguchi, Ryusuke Murakami, Tsukasa Baba, Ikuo Konishi
Condylomatous, or warty squamous cell carcinoma (SCC) of the uterine cervix, is a rare variant of invasive SCC. Here, we describe a case of aggressive condylomatous SCC of the uterine cervix. A 43-year-old woman was monitored for 3 years for suspected low-grade squamous intraepithelial lesion. A whitish papillary mass occupied the cervix, and the colposcopic diagnosis was condyloma acuminatum. A cervical biopsy revealed papillary proliferating thick squamous epithelium, which consisted of koilocytes and atypical cells with enlarged nuclei...
March 2018: Journal of Obstetrics and Gynaecology Research
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