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https://www.readbyqxmd.com/read/29166319/cardiometabolic-impact-of-changing-sitting-standing-and-stepping-in-the-workplace
#1
Elisabeth Ah Winkler, Sebastien Chastin, Elizabeth G Eakin, Neville Owen, Anthony D LaMontagne, Marj Moodie, Paddy C Dempsey, Bronwyn A Kingwell, David W Dunstan, Genevieve N Healy
BACKGROUND: According to cross-sectional and acute experimental evidence, reducing sitting time should improve cardio-metabolic health risk biomarkers. Furthermore, the improvements obtained may depend on whether sitting is replaced with standing or ambulatory activities. Based on data from the Stand Up Victoria multi-component workplace intervention, we examined this issue using compositional data analysis - a method that can examine and compare all activity changes simultaneously. METHODS: Participants receiving the intervention (n=136 ≥0...
November 21, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29166185/could-a-certain-sitting-position-reduce-the-pain-experienced-by-a-child-the-benefits-of-parental-holding-and-an-upright-position
#2
Ni Made Sri Rahyanti, Nani Nurhaeni, Dessie Wanda
Intravenous injection is the most feared medical procedure and gives rise to an experience of mild to severe pain in children. Unrestrained pain has a negative effect on the child. Pain management in the form of a convenient sitting position is needed by children who undergo intravenous injection procedures. This study aims to determine the effect of parental holding and an upright position on children's pain during intravenous injection procedures. The study used the Randomized Clinical Trial method involving 34 respondents, aged 1-4 years, who were included in the intervention and control group...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29165626/the-influence-of-physical-activity-and-sedentary-behavior-on-living-to-age-85-years-without-disease-and-disability-in-older-women
#3
Eileen Rillamas-Sun, Michael J LaMonte, Kelly R Evenson, Cynthia A Thomson, Shirley A Beresford, Mathilda C Coday, Todd M Manini, Wenjun Li, Andrea Z LaCroix
Background: Whether physical activity (PA) and sedentary behavior influence the odds of women living to age 85 years without chronic disease or disability is not well described. Methods: Participants of the Women's Health Initiative (n=49,612) were categorized based on health status by age 85 years: 1) lived without developing major chronic disease or mobility disability ("healthy"); 2) lived and developed mobility disability with or without disease; 3) lived and developed major chronic disease, but not mobility disability; and 4) died before their 85 th birth year...
November 20, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29164875/insights-into-the-mechanism-of-action-of-the-two-peptide-lantibiotic-lacticin-3147
#4
Alireza Bakhtiary, Stephen A Cochrane, Pascal Mercier, Ryan T McKay, Mark Miskolzie, Clarissa S Sit, John C Vederas
Lacticin 3147 is a two peptide lantibiotc (LtnA1 and LtnA2) that displays nanomolar activity against many Gram-positive bacteria. Lacticin 3147 may exert its antimicrobial effect by several mechanisms. Isothermal titration calorimetry experiments show that only LtnA1 binds to the peptidoglycan precursor lipid II, which could inhibit peptidoglycan biosynthesis. An experimentally supported model of the resulting complex suggests that the key binding partners are the C-terminus of LtnA1 and pyrophosphate of lipid II...
November 22, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29164029/a-clinical-practice-guideline-for-the-management-of-patients-with-acute-spinal-cord-injury-recommendations-on-the-type-and-timing-of-rehabilitation
#5
Michael G Fehlings, Lindsay A Tetreault, Bizhan Aarabi, Paul Anderson, Paul M Arnold, Darrel S Brodke, Kazuhiro Chiba, Joseph R Dettori, Julio C Furlan, James S Harrop, Gregory Hawryluk, Langston T Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Brian K Kwon, Ralph J Marino, Allan R Martin, Eric Massicotte, Geno Merli, James W Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C Skelly, Eve C Tsai, Alexander Vaccaro, Jefferson R Wilson, Albert Yee, Anthony S Burns
Introduction: The objective of this study is to develop guidelines that outline the appropriate type and timing of rehabilitation in patients with acute spinal cord injury (SCI). Methods: A systematic review of the literature was conducted to address key questions related to rehabilitation in patients with acute SCI. A multidisciplinary guideline development group used this information, and their clinical expertise, to develop recommendations for the type and timing of rehabilitation...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29164023/type-and-timing-of-rehabilitation-following-acute-and-subacute-spinal-cord-injury-a-systematic-review
#6
REVIEW
Anthony S Burns, Ralph J Marino, Sukhvinder Kalsi-Ryan, James W Middleton, Lindsay A Tetreault, Joseph R Dettori, Kathryn E Mihalovich, Michael G Fehlings
Objectives: The objective of this study was to conduct a systematic review of the literature to address the following clinical questions: In adult patients with acute and subacute complete or incomplete traumatic SCI, (1) does the time interval between injury and commencing rehabilitation affect outcome?; (2) what is the comparative effectiveness of different rehabilitation strategies, including different intensities and durations of treatment?; (3) are there patient or injury characteristics that affect the efficacy of rehabilitation?; and (4) what is the cost-effectiveness of various rehabilitation strategies? Methods: A systematic search was conducted for literature published through March 31, 2015 that evaluated rehabilitation strategies in adults with acute or subacute traumatic SCI at any level...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29163895/trapping-intermediate-mlct-states-in-low-symmetry-ru-bpy-complexes
#7
Alejandro Cadranel, Paola S Oviedo, German E Pieslinger, Shiori Yamazaki, Valeria D Kleiman, Luis M Baraldo, Dirk M Guldi
The picosecond excited state dynamics of [Ru(tpm)(bpy)(NCS)](+) (RubNCS(+) ) and [Ru(tpm)(bpy)(CN)](+) (RubCN(+) ) (tpm = tris(1-pyrazolyl)methane, bpy = 2,2'-bipyridine) have been analyzed by means of transient absorption measurements and spectroelectrochemistry. Emissive (3)MLCTs with (GS)HOMO(h(+))-(GS)LUMO(e(-)) configurations are the lowest triplet excited states regardless of whether 387 or 505 nm photoexcitation is used. 387 nm photoexcitation yields, after a few picoseconds, the emissive (3)MLCTs. In contrast, 505 nm photoexcitation populates an intermediate excited state that we assign as a (3)MLCT state, in which the hole sits in a metal-centered orbital of different symmetry, prior to its conversion to the emissive (3)MLCTs...
November 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29163120/the-myosuit-bi-articular-anti-gravity-exosuit-that-reduces-hip-extensor-activity-in-sitting-transfers
#8
Kai Schmidt, Jaime E Duarte, Martin Grimmer, Alejandro Sancho-Puchades, Haiqi Wei, Chris S Easthope, Robert Riener
Muscle weakness-which can result from neurological injuries, genetic disorders, or typical aging-can affect a person's mobility and quality of life. For many people with muscle weakness, assistive devices provide the means to regain mobility and independence. These devices range from well-established technology, such as wheelchairs, to newer technologies, such as exoskeletons and exosuits. For assistive devices to be used in everyday life, they must provide assistance across activities of daily living (ADLs) in an unobtrusive manner...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/29162662/i-sit-in-the-diabetic-clinic
#9
REVIEW
Mary Lindsay
No abstract text is available yet for this article.
December 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/29161844/a-network-model-for-control-of-dengue-epidemic-using-sterile-insect-technique
#10
Arti Mishra, Benjamin Ambrosio, Sunita Gakkhar, M A Aziz-Alaoui
In this paper, a network model has been proposed to control dengue disease transmission considering host-vector dynamics in n patches. The control of mosquitoes is performed by SIT. In SIT, the male insects are sterilized in the laboratory and released into the environment to control the number of offsprings. The basic reproduction number has been computed. The existence and stability of various states have been discussed. The bifurcation diagram has been plotted to show the existence and stability regions of disease-free and endemic states for an isolated patch...
April 1, 2018: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/29161779/micronuclei-assay-in-exfoliated-buccal-cells-of-radiation-treated-oral-cancer-patients
#11
Gayathri Ramesh, Smriti Chaubey, Amrita Raj, Ravi Kumar Seth, Anuradha Katiyar, Amit Kumar
BACKGROUND: Micronuclei are suitable internal dosimeters for revealing tissue-specific genotoxic damage in individuals exposed to carcinogenic mixtures. Evaluation of radiation-induced cellular changes to predict radiosensitivity has invested many investigators since such changes were first found in biopsy material. AIM: The aim of the present study was to assess the relationship of with histopathological grade and number of radiation therapy sittings with the frequency of micronuclei and nuclear anomalies among oral cancer patients...
November 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29159209/dynamics-of-pulicat-lake-mouth-analysis-using-geospatial-data-east-coast-of-india-implications-to-socio-economic-scenarios
#12
K Nagalaksmi, Madri Pramod Kumar, N Jayaraju, T Lakshmi Prasad, B Lakshmanna, G Sreenivasulu
Pulicat Lake is one of the major wetlands in India. It is the second largest brackish water lagoon in India next to Chilika Lake in Orissa state. Pulicat Lake sits beside the Bay of Bengal so, the study on the mouth is vital. The investigations were carried out by using multi-temporal satellite imageries of IRS P6, LISS III data for four years viz., 2009, 2011, 2012 and 2013. Subsequent changes in the width of the lake at the southern side were measured. It is found that the lake mouth is not static but dynamic predominantly fluctuating year by year...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29159019/introducing-sit-stand-desks-increases-classroom-standing-time-among-university-students
#13
Matthew Jerome, Kathleen F Janz, Barbara Baquero, Lucas J Carr
Excessive sedentary behavior has been associated with many negative health outcomes. While an understudied health topic, there is evidence that university students are excessively sedentary. Sit-stand desks have been shown to reduce sedentary time among pre-university students (ages 5-18 years) and sedentary workers but have not been tested in university classrooms. This study tested the effects of introducing sit-stand desks into a university classroom on student's classroom sitting and standing behaviors...
December 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29158767/screening-of-shox-gene-sequence-variants-in-saudi-arabian-children-with-idiopathic-short-stature
#14
Abdulla A Alharthi, Ehab I El-Hallous, Iman M Talaat, Hamed A Alghamdi, Matar I Almalki, Ahmed Gaber
Purpose: Short stature affects approximately 2%-3% of children, representing one of the most frequent disorders for which clinical attention is sought during childhood. Despite assumed genetic heterogeneity, mutations or deletions in the short stature homeobox-containing gene (SHOX) are frequently detected in subjects with short stature. Idiopathic short stature (ISS) refers to patients with short stature for various unknown reasons. The goal of this study was to screen all the exons of SHOX to identify related mutations...
October 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29158354/confirmatory-tests-for-the-diagnosis-of-primary-aldosteronism-a-prospective-diagnostic-accuracy-study
#15
Ying Song, Shumin Yang, Wenwen He, Jinbo Hu, Qingfeng Cheng, Yue Wang, Ting Luo, Linqiang Ma, Qianna Zhen, Suhua Zhang, Mei Mei, Zhihong Wang, Hua Qing, Dennis Bruemmer, Bin Peng, Qifu Li
The diagnosis of primary aldosteronism typically requires at least one confirmatory test. The fludrocortisone suppression test is generally accepted as a reliable confirmatory test, but it is cumbersome. Evidence from accuracy studies of the saline infusion test (SIT) and the captopril challenge test (CCT) has provided conflicting results. This prospective study aimed to evaluate the diagnostic accuracy of the SIT and CCT using fludrocortisone suppression test as the reference standard. One hundred thirty-five patients diagnosed with primary aldosteronism and 101 patients diagnosed with essential hypertension who completed the 3 confirmatory tests were included for the diagnostic accuracy analysis...
November 20, 2017: Hypertension
https://www.readbyqxmd.com/read/29157800/duchenne-muscular-dystrophy-with-platypnea-orthodeoxia-from-chilaiditi-syndrome
#16
Masashi Ogasawara, Akihiko Ishiyama, Akira Sugiura, Kazuhiko Segawa, Ikuya Nonaka, Eri Takeshita, Yuko Shimizu-Motohashi, Hirofumi Komaki, Masayuki Sasaki
INTRODUCTION: Chilaiditi syndrome is a rare pathophysiology in which the colon or other organs are interposed between the diaphragm and liver, and respiratory or digestive symptoms sometimes manifest. Although there have been some cases of Chilaiditi syndrome complicating neuromuscular disorders, none have described resulting respiratory or digestive symptoms. CASE PRESENTATION: Our patient was a 20-year-old man with DMD who had been receiving noninvasive positive-pressure ventilation during the night...
November 17, 2017: Brain & Development
https://www.readbyqxmd.com/read/29157152/the-compositional-isotemporal-substitution-model-a-method-for-estimating-changes-in-a-health-outcome-for-reallocation-of-time-between-sleep-physical-activity-and-sedentary-behaviour
#17
Dorothea Dumuid, Željko Pedišić, Tyman Everleigh Stanford, Josep-Antoni Martín-Fernández, Karel Hron, Carol A Maher, Lucy K Lewis, Timothy Olds
How people use their time has been linked with their health. For example, spending more time being physically active is known to be beneficial for health, whereas long durations of sitting have been associated with unfavourable health outcomes. Accordingly, public health messages have advocated swapping strategies to promote the reallocation of time between parts of the time-use composition, such as "Move More, Sit Less", with the aim of achieving optimal distribution of time for health. However, the majority of research underpinning these public health messages has not considered daily time use as a composition, and has ignored the relative nature of time-use data...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/29157133/reallocating-sitting-time-to-standing-or-stepping-through-isotemporal-analysis-associations-with-markers-of-chronic-low-grade-inflammation
#18
Joseph Henson, Charlotte L Edwardson, Danielle H Bodicoat, Kishan Bakrania, Melanie J Davies, Kamlesh Khunti, Duncan C S Talbot, Thomas Yates
Although high levels of sitting time are adversely related to health, it is unclear whether moving from sitting to standing provides a sufficient stimulus to elicit benefits upon markers of chronic low-grade inflammation in a population at high risk of type 2 diabetes (T2DM). Three hundred and seventy two participants (age = 66.8 ± 7.5years; body mass index (BMI) = 31.7 ± 5.5kg/m(2); Male = 61%) were included. Sitting, standing and stepping was determined using the activPAL3(TM) device. Linear regression modelling employing an isotemporal substitution approach was used to quantify the association of theoretically substituting 60 minutes of sitting per day for standing or stepping on interleukin-6 (IL-6), C-reactive protein (CRP) and leptin...
November 21, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29156339/silicification-process-in-diatom-algae-using-different-silicon-chemical-sources-colloidal-silicic-acid-interactions-at-cell-surface
#19
Silvia Casabianca, Antonella Penna, Samuela Capellacci, Michela Cangiotti, Maria Francesca Ottaviani
The silicon transport and use inside cells are key processes for understanding how diatoms metabolize this element in the silica biogenic cycle in the ocean. A spin-probe electron paramagnetic resonance (EPR) study over time helped to investigate the interacting properties and the internalization mechanisms of silicic acid from different silicon sources into the cells. Diatom cells were grown in media containing biogenic amorphous substrates, such as diatomaceous earth and sponge spicules, and crystalline sodium metasilicate...
November 14, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29154822/mef2-and-the-skeletal-muscle-differentiation-program
#20
REVIEW
Michael V Taylor, Simon M Hughes
Mef2 is a conserved and significant transcription factor in the control of muscle gene expression. In cell culture Mef2 synergises with MyoD-family members in the activation of gene expression and in the conversion of fibroblasts into myoblasts. Amongst its in vivo roles, Mef2 is required for both Drosophila muscle development and mammalian muscle regeneration. Mef2 has functions in other cell-types too, but this review focuses on skeletal muscle and surveys key findings on Mef2 from its discovery, shortly after that of MyoD, up to the present day...
November 14, 2017: Seminars in Cell & Developmental Biology
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