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dental fusion

O Nilsson, N Isoherranen, M H Guo, J C Lui, Y H Jee, I Guttmann-Bauman, C Acerini, W Lee, R Allikmets, J A Yanovski, A Dauber, J Baron
Nutritional excess of vitamin A, a precursor for retinoic acid (RA), causes premature epiphyseal fusion, craniosynostosis, and light-dependent retinopathy. Similarly, homozygous loss-of-function mutations in CYP26B1, one of the major RA-metabolizing enzymes, cause advanced bone age, premature epiphyseal fusion, and craniosynostosis. In this paper, a patient with markedly accelerated skeletal and dental development, retinal scarring, and autism-spectrum disease is presented and the role of retinoic acid in longitudinal bone growth and skeletal maturation is reviewed...
September 2, 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
Eshagh Ali Saberi, Sediqe Ebrahimipour
OBJECTIVES: The objective of this study was to evaluate the prevalence of dental developmental anomalies in digital panoramic radiographs of the patients referred to the Zahedan medical imaging center and to evaluate the frequency of anomalies regarding the disorders in shape, position and number in the Southeast of Iran. MATERIALS AND METHODS: A total of 1172 panoramic radiographs from 581 males and 586 females aged over 16 years were obtained from the files of the Zahedan medical imaging center between the years of 2014 and 2015...
July 2016: Journal of International Society of Preventive & Community Dentistry
L Arcuri, G De Vico, L Ottria, R Condò, L Cerroni, M Mancini, A Barlattani
AIM: To make a comparison between two different approaches of data matching during the preparation of a computer guided implant planning. MATERIAL AND METHODS: Electronic and manual literature searches were performed to collect information about the double-scan protocol and the smart fusion protocol. The two systems were then tested to identify or confirm their advantages and disadvantages. RESULTS: The double scan protocol is a reliable and well-known process to obtain a fusion between the anatomical data (CBCT) and the prosthetic data (radiographic template)...
May 2016: La Clinica Terapeutica
Ying Sun, Yi Yang, Dihan Zhou, Yuan Cao, Jie Yu, Bali Zhao, Maohua Zhong, Yaoming Li, Jingyi Yang, Huimin Yan
As the main etiologic bacterium of dental caries, Streptococcus mutans (S. mutans) has been considered as the primary object of vaccine research. We previously constructed a recombinant flagellin-rPAc fusion protein (KF-rPAc) that consists of an alanine-rich region and proline-rich region fragment of PAc (rPAc) from S. mutans and flagellin KF from E.coli K12 strain. Intranasal (i.n) immunization of KF-rPAc could induce high level of rPAc-specific antibody responses and offer robust protection against dental caries...
July 8, 2016: Human Vaccines & Immunotherapeutics
Alexa Bodman, Margaret Riordan, Lawrence S Chin
Spinal epidural abscesses are an uncommon cause of spinal cord injury but, depending on the size and presence of neurological deficits, urgent neurosurgical intervention may be required. We present a unique case of a patient presenting with a spinal epidural collection several days after a fall. While a spinal epidural hematoma was suspected based on the patient's history and MRI findings, a spinal epidural abscess was found during surgery. The patient underwent laminectomy and instrumented fusion with successful treatment of her infection...
2016: Curēus
Guillaume Choucroun, Julien Mourlaas, Nur Hafizah Kamar Affendi, Stuart J Froum, Sang-Choon Cho
PURPOSE: To present a classification and assess the presence and degree of cortication of the sinus floor utilizing Computerized Tomography (CT) scan images. MATERIALS AND METHODS: One hundred CT scans, of patient who required a sinus augmentation procedure (SAP), were evaluated and classified according to the Type of sinus floor cortication (SFC). Type 1: sinus floor showing similar or higher density than the surrounding cortical areas. Type 2: sinus floor showing less density than the surrounding cortical areas...
June 29, 2016: Clinical Implant Dentistry and related Research
Szu-Chuan Huang, Yi-Ywan M Chen
Ureolysis by Streptococcus salivarius is critical for pH homeostasis of dental plaque and prevention of dental caries. The expression of S. salivarius urease is induced by acidic pH and carbohydrate excess. The differential expression is mainly controlled at the transcriptional level from the promoter 5' to ureI (p ureI ). Our previous study demonstrates that CodY represses p ureI by binding to a CodY box 5' to p ureI , and the repression is more pronounced in cells grown at pH 7 than in cells grown at pH 5...
May 2016: MSphere
Eleni Naziri, Alexander Schramm, Frank Wilde
OBJECTIVES: The purpose of this study was to assess the accuracy of computer-assisted implant insertion based on computed tomography and template-guided implant placement. MATERIAL AND METHODS: A total of 246 implants were placed with the aid of 3D-based transfer templates in 181 consecutive partially edentulous patients. Five groups were formed on the basis of different implant systems, surgical protocols and guide sleeves. After virtual implant planning with the CoDiagnostiX Software, surgical guides were fabricated in a dental laboratory...
2016: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
Zachary D Moye, Minjun Son, Ariana E Rosa-Alberty, Lin Zeng, Sang-Joon Ahn, Stephen J Hagen, Robert A Burne
UNLABELLED: The capacity to internalize and catabolize carbohydrates is essential for dental caries pathogens to persist and cause disease. The expression of many virulence-related attributes by Streptococcus mutans, an organism strongly associated with human dental caries, is influenced by the peptide signaling pathways that control genetic competence. Here, we demonstrate a relationship between the efficiency of competence signaling and carbohydrate source. A significant increase in the activity of the promoters for comX, comS, and comYA after exposure to competence-stimulating peptide (CSP) was observed in cells growing on fructose, maltose, sucrose, or trehalose as the primary carbohydrate source, compared to cells growing on glucose...
August 1, 2016: Applied and Environmental Microbiology
Joe Iwanaga, Koichi Watanabe, Tsuyoshi Saga, Yoko Tabira, Koh-Ichi Yamaki
Along with the popularization of dental implant surgery, there has been considerable research on the lingual foramen using cone-beam computed tomography. Anatomical research has also revealed that the arteries entering the lingual foramina are branches of the submental and sublingual arteries. There have been no reports, however, of the submental or sublingual artery entering the mandible from the lingual foramen, perforating it, and then distributing to the inferior labial region. A 69-year-old man who donated his body to our department in 2015 was dissected...
2016: Case Reports in Dentistry
Gerlig Widmann, Bastian Fischer, Johannes Peter Michael Berggren, Albina Dennhardt, Peter Schullian, Bale Reto, Wolfgang Puelacher
PURPOSE: Cone beam computed tomography (CBCT) is increasingly overtaking multislice computed tomography (MSCT) for implant planning and computer-aided design/computer-assisted manufacturing (CAD/CAM) surgical guide fabrication. The purpose of this study was to evaluate whether the image modality has a significant influence on the accuracy of image-fusion stereolithographic guides. MATERIALS AND METHODS: A total of 240 implants were placed in 30 polymer models using surgical guides fabricated using CBCT or MSCT and optical scanning of dental casts and diagnostic wax-up...
May 2016: International Journal of Oral & Maxillofacial Implants
Hana Dosedělová, Kateřina Štěpánková, Tomáš Zikmund, Herve Lesot, Jozef Kaiser, Karel Novotný, Jan Štembírek, Zdeněk Knotek, Oldřich Zahradníček, Marcela Buchtová
Chameleon teeth develop as individual structures at a distance from the developing jaw bone during the pre-hatching period and also partially during the post-hatching period. However, in the adult, all teeth are fused together and tightly attached to the jaw bone by mineralized attachment tissue to form one functional unit. Tooth to bone as well as tooth to tooth attachments are so firm that if injury to the oral cavity occurs, several neighbouring teeth and pieces of jaw can be broken off. We analysed age-related changes in chameleon acrodont dentition, where ankylosis represents a physiological condition, whereas in mammals, ankylosis only occurs in a pathological context...
September 2016: Journal of Anatomy
M Basalamah, K Baroudi
Practitioners and policy-makers need information about the relative frequency of dental anomalies among children in their region. This study investigated the prevalence of different oral anomalies among schoolchildren in Sana'a city, Yemen. A sample of 1000 private and public schoolchildren aged 4-12 years were examined by the same examiner using disposable tongue blades. The total prevalence of oral anomalies was 15.1%, most commonly in boys (male:female ratio 3.2:1) aged 7-12 years. The most prevalent dental anomaly related to hard tissues was tooth hypoplasia (2...
January 2016: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
C D Hermann, S L Hyzy, R Olivares-Navarrete, M Walker, J K Williams, B D Boyan, Z Schwartz
Craniosynostosis occurs in approximately 1 in 2,000 children and results from the premature fusion of ≥1 cranial sutures. If left untreated, craniosynostosis can cause numerous complications as related to an increase in intracranial pressure or as a direct result from cranial deformities, or both. More than 100 known mutations may cause syndromic craniosynostosis, but the majority of cases are nonsyndromic, occurring as isolated defects. Most cases of craniosynostosis require complex cranial vault reconstruction that is associated with a high risk of morbidity...
July 2016: Journal of Dental Research
Gozde Ozcan, Ahmet Ercan Sekerci, Emrah Soylu, Sinan Nazlim, Mehmet Amuk, Fatma Avci
Fusion is an abnormality of tooth development defined as the union of two developing dental germs, resulting in a single large dental structure. This irregular tooth morphology is associated with a high predisposition to dental caries and periodontal diseases. As a result of recurring inflammatory periodontal processes, disorders such as periodontal pocket, pericoronitis, and paradental cysts may develop. A rare mandibular anatomic variation is the retromolar canal, which is very significant for surgical procedures...
March 2016: Imaging Science in Dentistry
Ruchi Juneja, Varun Kumar
Teeth with aberrant anatomy present a challenge to the endodontist. Advanced tools like cone beam computed tomography aid in exploring the details of endodontic architecture in such cases. The aim of this case report is to highlight the advantage of CBCT in endodontic management of teeth with multiple dental anomalies. A mandibular lateral incisor associated with an extraoral sinus tract revealed unusual clinical anatomy. A provisional diagnosis of type III dens in dente was made based on radiographic findings...
February 2016: Journal of Clinical and Diagnostic Research: JCDR
Melanie Melcher, Sandra J Facey, Thorsten M Henkes, Thomas Subkowski, Bernhard Hauer
Calcium phosphate mineralization is of particular interest in dental repair. A biomimetic approach using proteins or peptides is a highly promising way to reconstruct eroded teeth. In this study, the screening of several proteins is described for their binding and nucleating activities toward hydroxyapatite. Out of 27 tested candidates, only two hydrophobin fusion proteins showed binding abilities to hydroxyapatite in a mouthwash formulation and an increased nucleation in artificial saliva. Using a semirational approach, one of the two candidates (DEWA_5), a fusion protein consisting of a truncated section of the Bacillus subtilis synthase YaaD, the Aspergillus nidulans hydrophobin DEWA, and the rationally designed peptide P11-4 described in the literature, could be further engineered toward a faster mineral formation...
May 9, 2016: Biomacromolecules
Oana Carmen Drăgan, Alexandru Ştefan Fărcăşanu, Radu Septimiu Câmpian, Romulus Valeriu Flaviu Turcu
BACKGROUND AND AIMS: Visualization of the internal and external root canal morphology is very important for a successful endodontic treatment; however, it seems to be difficult considering the small size of the tooth and the complexity of the root canal system. Film-based or digital conventional radiographic techniques as well as cone beam computed tomography provide limited information on the dental pulp anatomy or have harmful effects. A new non-invasive diagnosis tool is magnetic resonance imaging, due to its ability of imaging both hard and soft tissues...
2016: Clujul Medical (1957)
Gejin Wei, Zhiyun Wang, Fuzhi Ai, Qingshui Yin, Zenghui Wu, Xiang Yang Ma, Junjie Xu, Chenglong Shi, Hong Xia
BACKGROUND: Klippel-Feil syndrome (KFS) is characterized by congenital vertebral fusion of the cervical spine and a wide spectrum of associated anomalies. In patients with KFS with basilar invagination (BI), compression of the brainstem and upper cervical cord results in neurological deficits, and decompression and occipitocervical reconstruction are required. The highly varied anatomy of KFS makes a posterior occipitocervical fixation strategy challenging. For these patients, the transoral atlantoaxial reduction plate (TARP) operation is an optimal option to perform a direct anterior fixation to achieve stabilization...
April 2016: Neurosurgery
Faezeh Ghaderi, Azade Rafiee
Dental anomaly in number, size and shape might be due to excessive activation of dental lamina during the morpho-differentiation stage. Fusion is one of the most unusual and rare anomalies of shape of the teeth. It frequently involves the supernumerary teeth resulting in a challenging differential diagnosis with gemination. Dental anomalies may result in different problems such as delayed eruption and crowding; thus, early diagnosis is required for effective intervention and proper in-time treatment. The case reported here is a 4-year-old girl with bilateral supernumerary primary maxillary lateral incisors associated with fusion between primary maxillary left lateral incisor and supernumerary lateral tooth...
March 2016: Journal of Dentistry
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