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dental fusion

Masoumeh Johari, Milad Abdollahzadeh, Farzad Esmaeili, Vahideh Sakhamanesh
Background: Dental cone beam computed tomography (CBCT) images suffer from severe metal artifacts. These artifacts degrade the quality of acquired image and in some cases make it unsuitable to use. Streaking artifacts and cavities around teeth are the main reason of degradation. Methods: In this article, we have proposed a new artifact reduction algorithm which has three parallel components. The first component extracts teeth based on the modeling of image histogram with a Gaussian mixture model...
January 2018: Journal of Medical Signals and Sensors
Madhuram Krishnamurthy, V Naveen Kumar, Ashok Leburu, Nadeem Jeddy
Fusion and gemination are developmental anomalies which are quite similar to each other but can be distinguished from each other if properly assessed. Fusion and gemination have been described as a result of developmental anomalies of dental tissues. The exact etiology is still unknown, but a genetic predisposition is suggested. This article highlights the importance of clinical and radiographic correlation in arriving at a definitive diagnosis.
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Ji-Myung Bae, John C Clarke, Harunur Rashid, Mitra D Adhami, Kayla McCullough, Jordan S Scott, Haiyan Chen, Krishna M Sinha, Benoit de Crombrugghe, Amjad Javed
The Sp7/Osterix transcription factor is essential for bone development. Mutations of Sp7 gene in humans are associated with craniofacial anomalies and osteogenesis imperfecta. However, the role of Sp7 in embryonic tooth development remains unknown. Here we identified the functional requirement of Sp7 for dentin synthesis and tooth development. Sp7-null mice exhibit craniofacial dysmorphogenesis and are completely void of alveolar bone. Surprisingly, initial tooth morphogenesis progressed normally in Sp7-null mice...
February 5, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Hatice Açıkel, Sevgin İbiş, Emine Şen Tunç
OBJECTIVE: The aim of this study was to investigate the characteristics of primary fused teeth (PFT) and its effects on permanent dentition in a group of Turkish children. SUBJECTS AND METHODS: Dental records of 13,450 paediatric patients who attended the Paediatric Dental Clinic in Northern Turkey between 2015 and 2017 were reviewed. Forty patients had been diagnosed with PFT and were included in this study. Clinical and radiographic examinations were conducted, and the distribution of PFT was calculated by type, sex, affected jaw, associated dental anomalies and clinical complications...
February 1, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Suzanne Tanya Nethan, Shruti Sinha, Sunira Chandra
The Ellis-van Creveld (EVC) syndrome is a chondroectodermal dysplasia and is characterized by the cardinal features of disproportionate short stature, polydactyly, hidrotic ectodermal dysplasia, and congenital heart malformations, along with other skeletal and dental abnormalities. It is a rare condition, with very few cases reported in the medical literature. It is inherited as an autosomal recessive disorder with variable expressions, due to the mutation of the EVC syndrome 1 and 2 genes, which are located on chromosome 4p16...
September 2017: Iranian Journal of Medical Sciences
Yumiko I Matsuishi, Hiroki Kato, Keiji Masuda, Haruyoshi Yamaza, Yuta Hirofuji, Hiroshi Sato, Hiroko Wada, Tamotsu Kiyoshima, Kazuaki Nonaka
Undifferentiated odontogenic epithelium and dental papilla cells differentiate into ameloblasts and odontoblasts, respectively, both of which are essential for tooth development. These differentiation processes involve dramatic functional and morphological changes of the cells. For these changes to occur, activation of mitochondrial functions, including ATP production, is extremely important. In addition, these changes are closely related to mitochondrial fission and fusion, known as mitochondrial dynamics...
January 8, 2018: Biochemical and Biophysical Research Communications
Mohamed A A Hegazy, Mohamed Elsayed Eldib, Daniel Hernandez, Myung Hye Cho, Min Hyoung Cho, Soo Yeol Lee
PURPOSE: In a dental CT scan, the presence of dental fillings or dental implants generates severe metal artifacts that often compromise readability of the CT images. Many metal artifact reduction (MAR) techniques have been introduced, but dental CT scans still suffer from severe metal artifacts particularly when multiple dental fillings or implants exist around the region of interest. The high attenuation coefficient of teeth often causes erroneous metal segmentation, compromising the MAR performance...
February 2018: Medical Physics
Hakan Bulut, Aylin Pasaoglu
Fusion of teeth is a developmental anomaly. It occurs at the stage of tooth formation, which determines the shape and size of the tooth crown, when one or more teeth fuse at the dentin level during the morphodifferentiation of the dental germs. Such teeth show macrodontia and may cause crowding, as well as esthetic and endodontic problems. In this article, we report a rare case of a maxillary central incisor fused to a supernumerary tooth showing labial and palatal talon cusps, which was orthodontically moved across the midpalatal suture...
November 2017: Korean Journal of Orthodontics
Priti Sushil Jain, Tejashri Shreyas Gupte, Abdulkadeer M Jetpurwala, Shely Pratik Dedhia
Managing patients with rare genetic disorders is a challenge that dentists face often. Robinow syndrome (RS) is one such rare genetic disorder with <200 cases reported worldwide. RS demonstrates multiple craniofacial abnormalities and orodental disorders, which need to be taken into consideration by a dental practitioner while rendering dental care.
July 2017: Contemporary Clinical Dentistry
Yang Yang, Franz-Xaver Reichl, Jianwei Shi, Xiuli He, Reinhard Hickel, Christof Högg
OBJECTIVE: Previously, single composite components were used to study cytotoxicity and induction of DNA double-strand breaks (DNA-DSBs) of dental composite resins. In the present study, cytotoxicity and induction of DNA-DSBs in human gingival fibroblasts (HGFs) were investigated with dental composite eluates consisting of multiple components. The eluates were qualified and quantified. METHODS: The composites Esthet.X(®) HD, Venus(®), X-tra fil(®), CLEARFIL™ AP-X, Admira(®) Fusion and QuiXfil(®) were polymerized and immersed into Dulbecco's modified Eagle's medium (DMEM) for 72h...
October 14, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
Lisa Bodden, Nina Lümkemann, Valerie Köhler, Marlis Eichberger, Bogna Stawarczyk
OBJECTIVE: The aim of this study was to investigate the impact of a heating/quenching process on the optical, mechanical and thermodynamic properties of filled (20%_4000) and unfilled PEEK films (0%_2000 and 0%_4000). Heating/quenching was performed to simulate thermoforming as possible method to process thermoplastic polymers for dental application. METHODS: For the investigation, films of different PEEK qualities (0%_2000, 0%_4000, 20%_4000) were produced using isostatic pressing (n=10/quality)...
December 2017: Dental Materials: Official Publication of the Academy of Dental Materials
Nebiha Hilal Bilge, Selin Yeşiltepe, Kübra Törenek Ağırman, Fatma Çağlayan, Osman Murat Bilge
BACKGROUND: This study was performed to evaluate the prevalence of all types and subtypes of dental anomalies among 6 to 40 year-old patients by using panoramic radiographs. MATERIALS AND METHODS: This cross-sectional study was conducted by analyzing digital panoramic radiographs of 1200 patients admitted to our clinic in 2014. Dental anomalies were examined under 5 types and 16 subtypes. Dental anomalies were divided into five types: (a) number (including hypodontia, oligodontia and hyperdontia); (b) size (including microdontia and macrodontia); (c) structure (including amelogenesis imperfecta, dentinogenesis imperfecta and dentin dysplasia); (d) position (including transposition, ectopia, displacement, impaction and inversion); (e) shape (including fusion-gemination, dilaceration and taurodontism); RESULTS: The prevalence of dental anomalies diagnosed by panoramic radiographs was 39...
September 21, 2017: Folia Morphologica (Warsz)
Francesco Mangano, Carlo Mangano, Adriano Piattelli, Giovanna Iezzi
BACKGROUND: Direct metal laser sintering (DMLS) is an additive manufacturing technique that allows the fabrication of dental implants layer by layer through the laser fusion of titanium microparticles. The surface of DMLS implants is characterized by a high open porosity with interconnected pores of different sizes; therefore, it has the potential to enhance and accelerate bone healing. To date, however, there are no histologic/histomorphometric studies in the literature evaluating the interface between bone and DMLS implants in the long-term...
2017: BioMed Research International
Carolina Sbordone, Paolo Toti, Ranieri Martuscelli, Franco Guidetti, Massimo Porzio, Ludovico Sbordone
BACKGROUND: Alveolar ridge volume loss may be minimized when postextraction sockets are filled by bone substitutes. PURPOSE: The aim of the study was to measure the effect of alveolar ridge preservation (ARP) in maintaining the external contour of the ridge after fresh socket grafting with or without particulate anorganic bovine bone mineral (BBM) and resorbable barrier covering. MATERIALS AND METHODS: In the present controlled study, patients subjected to single-tooth extraction were allocated to 2 groups: postextraction sockets grafted with bovine bone mineral (bbm), and naturally healing sockets (nat)...
December 2017: Clinical Implant Dentistry and related Research
Jingyi Yang, Ying Sun, Rong Bao, Dihan Zhou, Yi Yang, Yuan Cao, Jie Yu, Bali Zhao, Yaoming Li, Huimin Yan, Maohua Zhong
Dental caries is one of the most common global chronic diseases affecting all ages of the population; thus a vaccine against caries is urgently needed. Our previous studies demonstrated that a fusion protein, KF-rPAc, in which rPAc of S. mutans is directly fused to the C-terminal of E. coli-derived flagellin (KF), could confer high prophylactic and therapeutic efficiency against caries. However, possible side effects, including the high antigenicity of flagellin and possible inflammatory injury induced by flagellin, may restrict its clinical usage...
September 11, 2017: Scientific Reports
Mridula Goswami, Babita Jangra
Fusions of teeth and talon cusp are two rare developmental dental anomalies, affecting both primary and permanent dentitions. Both the anomalies are mostly reported as isolated finding and are rarely associated with other dental anomalies. Talon cusp is more common in maxillary anterior teeth in permanent dentition and fusion is commonly reported in mandibular teeth in primary dentition. The concomitant occurrence of talon cusp and fusion is rare and its occurrence in fused mandibular permanent teeth is also rare...
April 2017: International Journal of Clinical Pediatric Dentistry
Matthew De Furio, Sang Joon Ahn, Robert A Burne, Stephen J Hagen
The dental caries pathogen Streptococcus mutans is continually exposed to several types of stress in the oral biofilm environment. Oxidative stress generated by reactive oxygen species has a major impact on the establishment, persistence, and virulence of S. mutans Here, we combined fluorescent reporter-promoter fusions with single-cell imaging to study the effects of reactive oxygen species on activation of genetic competence in S. mutans Exposure to paraquat, which generates superoxide anion, produced a qualitatively different effect on activation of expression of the gene for the master competence regulator, ComX, than did treatment with hydrogen peroxide (H2O2), which can yield hydroxyl radical...
November 15, 2017: Applied and Environmental Microbiology
Ji-Hyeon Oh, Xueyin An, Seung-Mi Jeong, Byung-Ho Choi
PURPOSE: The purpose of this article was to describe a fully digital workflow used to perform computer-guided flapless implant placement in an edentulous patient without the use of conventional impressions, models, or a radiographic guide. MATERIALS AND METHODS: Digital data for the workflow were acquired using an intraoral scanner and cone-beam computed tomography (CBCT). The image fusion of the intraoral scan data and CBCT data was performed by matching resin markers placed in the patient's mouth...
December 2017: Journal of Oral and Maxillofacial Surgery
Lin Zeng, Brinta Chakraborty, Tanaz Farivar, Robert A Burne
The glucose/mannose-phosphotransferase system (PTS) permease EII(Man) encoded by manLMN in the dental caries pathogen Streptococcus mutans has a dominant influence on sugar-specific, CcpA-independent catabolite repression (CR). Mutations in manL affect energy metabolism and virulence-associated traits, including biofilm formation, acid tolerance, and competence. Using promoter::reporter fusions, expression of the manLMN and the fruRKI operons, encoding a transcriptional regulator, a fructose-1-phosphate kinase and a fructose-PTS permease EII(Fru), respectively, was monitored in response to carbohydrate source and in mutants lacking CcpA, FruR, and components of EII(Man) Expression of genes for EII(Man) and EII(Fru) was directly regulated by CcpA and CR, as evinced by in vivo and in vitro methods...
November 1, 2017: Applied and Environmental Microbiology
Y J Zhao, Y Liu, Y C Sun, Y Wang
OBJECTIVE: To explore a three-dimensional (3D) data fusion and integration method of optical scanning tooth crowns and cone beam CT (CBCT) reconstructing tooth roots for their natural transition in the 3D profile. METHODS: One mild dental crowding case was chosen from orthodontics clinics with full denture. The CBCT data were acquired to reconstruct the dental model with tooth roots by Mimics 17.0 medical imaging software, and the optical impression was taken to obtain the dentition model with high precision physiological contour of crowns by Smart Optics dental scanner...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
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