Natalie F Shur, Elizabeth J Simpson, Hannah Crossland, Despina Constantin, Sally M Cordon, Dumitru Constantin-Teodosiu, Francis B Stephens, Matthew S Brook, Philip J Atherton, Kenneth Smith, Daniel J Wilkinson, Olivier E Mougin, Christopher Bradley, Ian A Macdonald, Paul L Greenhaff
BACKGROUND: Bed-rest (BR) of only a few days duration reduces muscle protein synthesis and induces skeletal muscle atrophy and insulin resistance, but the scale and juxtaposition of these events have not been investigated concurrently in the same individuals. Moreover, the impact of short-term exercise-supplemented remobilization (ESR) on muscle volume, protein turnover and leg glucose uptake (LGU) in humans is unknown. METHODS: Ten healthy males (24 ± 1 years, body mass index 22...
February 12, 2024: Journal of Cachexia, Sarcopenia and Muscle