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bed rest

Suymara Toledo Miranda, Antonio Teixeira de Matos, Gheila Corrêa Ferres Baptestini, Alisson Carraro Borges
In horizontal subsurface flow constructed wetlands (HSSF-CWs), the main operational problem is clogging of the porous medium. In this study, the unclogging of HSSF-CWs was evaluated, at rest, by adding a nitrogen-based nutrient solution to the influent. For this, six HSSF-CWs were used, consisting of two uncultivated (CW-C), two cultivated with Tifton 85-grass (Cynodon spp.) (CW-T) and two cultivated with alligator weed (Alternanthera philoxeroides) (CW-A), which were fully clogged after being used for the treatment of swine wastewater...
October 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
Juquan Song, Melody R Saeman, Lisa A Baer, Anthony R Cai, Charles E Wade, Steven E Wolf
This study investigated microRNA and target gene profiles under different conditions of burn, bed rest, and exercise training. Male Sprague-Dawley rats (n = 48) were assigned to sham ambulatory, sham hindlimb unloading, burn ambulatory, or burn plus hindlimb unloading groups. Rats received a 40% TBSA scald burn or sham treatments and were ambulatory or hindlimb unloaded. Rats were further assigned to exercise or no exercise. Plantaris tissues were harvested on day 14 and pooled to analyze for microRNA and gene expression profiles...
September 28, 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
Zena Eh Moore, Menno T van Etten, Jo C Dumville
BACKGROUND: Pressure ulcers, which are localised injury to the skin or underlying tissue, or both, occur when people are unable to reposition themselves to relieve pressure on bony prominences. Pressure ulcers are often difficult to heal, painful, and impact negatively on the individual's quality of life. International guidelines suggest bed rest as a component of the treatment strategy to manage pressure ulcers among wheelchair users. The potential benefits and risks need to be considered when assessing the effectiveness of bed rest as an intervention for treating pressure ulcers in this population...
October 17, 2016: Cochrane Database of Systematic Reviews
Dean W Beebe, Julie Field, Megan M Milller, Lauren E Miller, Elizabeth LeBlond
STUDY OBJECTIVES: Investigate whether a realistic "dose" of shortened sleep, relative to a well-rested state, causes a decline in adolescents' learning and an increase in inattentive and sleepy behaviors in a simulated classroom setting. METHODS: Eighty-seven healthy 14.0-16.9 year-olds underwent a 3-week sleep manipulation protocol, including two 5-night sleep manipulation conditions presented in a randomly counterbalanced within-subjects cross-over design. Wake time was held constant...
October 10, 2016: Sleep
Chang-Hoon Jeon, Nam-Su Chung, Jae-Heon Lee, Han-Dong Lee
Bleeding and hematoma formation is rarely reported in percutaneous vertebroplasty procedure. An 84 year old male presented with a large paraspinal muscle hematoma after a percutaneous vertebroplasty. The patient had neither any prior bleeding disorder nor any anticoagulant treatment. Vital signs of the patient were unstable, and his hemoglobin level decreased daily. After a month of conservative treatment, including transfusion, cryotherapy, pain control and bed rest, his hemoglobin level remained stable and he showed relief from pain...
September 2016: Indian Journal of Orthopaedics
Gianni Biolo, Rado Pišot, Sara Mazzucco, Filippo Giorgio Di Girolamo, Roberta Situlin, Stefano Lazzer, Bruno Grassi, Carlo Reggiani, Angelina Passaro, Joern Rittweger, Mladen Gasparini, Boštjan Šimunič, Marco Narici
BACKGROUND & AIMS: Aging and experimental bed rest are associated with muscle atrophy and resistance to post-prandial stimulation of protein synthesis or anabolic resistance (AR). We have used in young and older adult volunteers, during short-term bed rest, a quick and non-invasive method, based on a single oral bolus of the stable isotope L[ring-(2)H5]phenylalanine (D5Phe), to determine post-prandial AR, defined as ratio between irreversible hydroxylation and incorporation into body protein of ingested phenylalanine...
September 30, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Hiroshi Matsuo, Yoshie Nakajima, Tomohiro Ogawa, Makoto Mo, Junichi Tazaki, Takahiro Doi, Norikazu Yamada, Takeo Suzuki, Hiromu Nakajima
Objective: To investigate the usefulness of D-dimer as a screening method as well as to explore potent predictors of deep vein thrombosis (DVT) in hospitalized Japanese patients with acute medical diseases/episodes. Methods and Subjects: This study was a multi-center, prospective, observational study. The inclusion criteria were hospitalized patients at high risk of developing venous thromboembolism with; (1) congestive heart failure, acute exacerbation of chronic obstructive pulmonary disease, infectious diseases, or inflammatory diseases, (2) bed rest ≥4 days, and (3) ≥60 years old...
2016: Annals of Vascular Diseases
Stefan Mendt, Martina Anna Maggioni, Michael Nordine, Mathias Steinach, Oliver Opatz, Daniel Belavý, Dieter Felsenberg, Jochim Koch, Peng Shang, Hanns-Christian Gunga, Alexander Stahn
Continuous recordings of core body temperature (CBT) are a well-established approach in describing circadian rhythms. Given the discomfort of invasive CBT measurement techniques, the use of skin temperature recordings has been proposed as a surrogate. More recently, we proposed a heat-flux approach (the so-called Double Sensor) for monitoring CBT. Studies investigating the reliability of the heat-flux approach over a 24-hour period, as well as comparisons with skin temperature recordings, are however lacking...
October 11, 2016: Chronobiology International
Julien Mysoet, Marie-Hélène Canu, Christophe Gillet, Julie Fourneau, Cyril Garnier, Bruno Bastide, Erwan Dupont
Immobilization, bed rest, or sedentary lifestyle, are known to induce a profound impairment in sensorimotor performance. These alterations are due to a combination of peripheral and central factors. Previous data conducted on a rat model of disuse (hindlimb unloading, HU) have shown a profound reorganization of motor cortex and an impairment of motor performance. Recently, our interest was turned towards the role of insulin-like growth factor 1 (IGF-1) in cerebral plasticity since this growth factor is considered as the mediator of beneficial effects of exercise on the central nervous system, and its cortical level is decreased after a 14-day period of HU...
October 4, 2016: Behavioural Brain Research
Ana Lúcia de Medeiros, Sérgio Ribeiro Dos Santos, Rômulo Wanderley de Lima Cabral, Juliana Paiva Góes Silva, Neyce de Matos Nascimento
Objective: To evaluate the use of nursing diagnoses and interventions proposed for women in labour and high-risk pregnancies. Method: This is a descriptive, retrospective study with documentary analysis of 1000 medical records and a checklist conducted from July to September 2014, at a maternity hospital in Paraiba, Brazil. It consisted of analysing descriptive measures and comparing the relationship between nursing diagnoses and interventions using NANDA - International and the Nursing Interventions Classification...
September 29, 2016: Revista Gaúcha de Enfermagem
Fares Gouzi, Jonathan Maury, François Bughin, Marine Blaquière, Bronia Ayoub, Jacques Mercier, Antonia Perez-Martin, Pascal Pomiès, Maurice Hayot
BACKGROUND AND AIMS: Targeting the early mechanisms in exercise-induced arterial hypertension (which precedes resting arterial hypertension in its natural history) may improve cardiovascular morbidity and mortality in COPD patients. Capillary rarefaction, an early event in COPD before vascular remodeling, is a potential mechanism of exercise-induced and resting arterial hypertension. Impaired training-induced capillarization was observed earlier in COPD patients; thus, this study compares the changes in blood pressure (BP) during exercise in COPD patients and matches control subjects (CSs) after a similar exercise training program, in relationship with muscle capillarization...
2016: International Journal of Chronic Obstructive Pulmonary Disease
Edip Güvenç Çekiç, Özcan Başaran, Nesrin Filiz Başaran, Onur Elmas, Volkan Doğan, Gurbet Özge Mert, Kadir Uğur Mert, Ibrahim Altun, Fatih Akın, Murat Biteker
BACKGROUND AND AIM: Decreased vascular reactivity in atherosclerosis was previously shown. In our study, it was aimed to demonstrate the decreased vascular functions in both microvascular and macrovascular tissues and to estimate any correlation between them. METHODS: Twenty-five control outpatients with no coronary artery disease (CAD) history and 26 outpatients with CAD history were enrolled in the study. Local cutaneous post-occlusive reactive hyperemia (PORH) responses after three minutes of brachial occlusion with a pneumatic cuff were recorded noninvasively by a Perimed Periflux 5010 laser Doppler flow system...
September 28, 2016: Microvascular Research
Daniel L Belavý, Ulf Gast, Dieter Felsenberg
PURPOSE: To investigate atrophy in the deep abdominal muscles, spinal extensors and the impact of high-load resistive exercise with and without whole body vibration following 60d of strict bed-rest. METHODS: 24 subjects underwent 60-days of head-down tilt bed-rest and performed either resistive vibration exercise (RVE), resistive exercise only (RE) or no exercise control (2nd Berlin BedRest Study). The thickness of the transversus abdominis, internal oblique and erector spinae muscles and area of the multifidus muscle were measured bilaterally via real-time ultrasound...
September 28, 2016: Medicine and Science in Sports and Exercise
D Lo Presti, G Gagliardi, G M Tiralongo, I Pisani, B Vasapollo, G P Novelli, H Valensise
OBJECTIVE: The objective of this study was to test the efficacy of bed rest in reducing total vascular resistance (TVR) in normotensive patients with TVR in the upper limits, evaluating the effect on fetal growth. METHODS: Thirty women patients were enrolled between 27 and 29 weeks gestation. All the patients met the following criteria: normal blood pressure values before and during pregnancy, TVR between 1300 and 1400 dyne sec_1 cm_5, normal fetal Doppler parameters at enrollment, abdominal circumference between the 10th and 25th centile...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
Emilie Viollet, Fabrice Nouvel, Dominique Richard, Mylène Blot, Arnaud Dupeyron
OBJECTIVE: Heel bedsore is frequent in population motionless more than 50years old. The score of risk of bedsore do not take into account the biomechanical factor, as the flessum of knee. The main objective of this study is to evaluate the relationship between the angle of knee flexion in a supine position with joint relaxation and the maximum interface pressure at the heel area. MATERIAL/PATIENTS AND METHODS: This study is a cohort with one investigator center, which is in MPR department, CHU de Nîmes...
September 2016: Annals of Physical and Rehabilitation Medicine
Yingbai Chen, Yunhai Tu, Ben Chen, Jieliang Shi, Bo Yu, Wencan Wu
PURPOSE: To assess the feasibility and efficacy of endoscopic transnasal removal of cavernous hemangiomas of the optic canal. DESIGN: Retrospective, non-comparative case series. METHODS: Eleven consecutive patients (11 eyes) with cavernous hemangioma of the optic canal underwent endoscopic trans-ethmoidal-sphenoidal removal of the tumor at the Eye Hospital of Wenzhou Medical University from January 2009 to March 2016. In each case, the indication for surgery was decreased visual acuity due to the tumor...
September 23, 2016: American Journal of Ophthalmology
Vanderson S Sampaio, Tatiana P Beltrán, Kevin C Kobylinski, Gisely C Melo, José B P Lima, Sara G M Silva, Íria C Rodriguez, Henrique Silveira, Maria G V B Guerra, Quique Bassat, Paulo F P Pimenta, Marcus V G Lacerda, Wuelton M Monteiro
BACKGROUND: Strategies designed to advance towards malaria elimination rely on the detection and treatment of infections, rather than fever, and the interruption of malaria transmission between mosquitoes and humans. Mass drug administration with anti-malarials directed at eliminating parasites in blood, either to entire populations or targeting only those with malaria infections, are considered useful strategies to progress towards malaria elimination, but may be insufficient if applied on their own...
2016: Malaria Journal
Kun Soo Jang, Hyeun Sung Kim
Complex regional pain syndrome (CRPS) type II is a syndrome that develops after nerve injury. Symptoms may be severe, and vary depending on the degree of sympathetic nerve involvement. As yet, there is no satisfactory treatment. We report the case of a female patient who had an L5 left transverse process fracture and an S2 body fracture, who developed symptoms of CRPS type II in her left lower leg that were aggravated during ambulation in spite of absolute bed rest for one month after the trauma. Several treatments, including bed rest, medication, and numerous nerve blocks were attempted, but the pain persisted...
September 2016: Journal of Korean Neurosurgical Society
G Xu, J S Hansen, X J Zhao, S Chen, M Hoene, X L Wang, J O Clemmesen, N H Secher, H U Häring, B K Pedersen, R Lehmann, C Weigert, P Plomgaard
BACKGROUND: Plasma acylcarnitine levels are elevated by physiological conditions such as fasting and exercise but also in states of insulin resistance and obesity. AIM: To elucidate the contribution of liver and skeletal muscle to plasma acylcarnitines in the fasting state and during exercise in humans. METHODS: In two independent studies young healthy males fasted overnight and performed an acute bout of exercise to investigate either acylcarnitines in skeletal muscle biopsies and arterial-to-venous plasma differences over the exercising and resting leg (n=9) or the flux over the hepato-splanchnic bed (n=10)...
September 20, 2016: Journal of Clinical Endocrinology and Metabolism
Krystin Zeller Meidell, Ryan Robinson, Adriana Vieira-de-Abreu, Adam J Gormley, Hamidreza Ghandehari, David W Grainger, Robert A Campbell
Integrin-targeting peptide RGDfK-labeled gold nanorods (GNR) seek to improve hyperthermia targeted to solid tumors by exploiting the known up-regulation of integrin αvβ3 cell membrane proteins on solid tumor vasculature surfaces. Tumor binding specificity might be expected since surrounding tissues and endothelial cells have limited numbers of these receptors. However, RGD peptide binding to many proteins is promiscuous, with known affinity to several families of cell integrin receptors, and also possible binding to platelets after intravenous infusion via a different integrin receptor, αIIbβ3, on platelets...
September 20, 2016: Journal of Biomedical Materials Research. Part A
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