keyword
https://read.qxmd.com/read/34408542/preparation-and-evaluation-of-benzalkonium-chloride-hand-sanitizer-as-a-potential-alternative-for-alcohol-based-hand-gels
#21
JOURNAL ARTICLE
Alhassan H Aodah, Abrar A Bakr, Rayan Y Booq, Mohammed J Rahman, Dunia A Alzahrani, Khulud A Alsulami, Hassa A Alshaya, Mohammed S Alsuabeyl, Essam J Alyamani, Essam A Tawfik
Hand hygiene is one of the effective measures for reducing the transmission of infections. Alcohol-based hand sanitizers containing ethanol or isopropanol are considered efficient alternatives to handwashing with water and soap. Despite being effective against a broad-spectrum of microbes, fining an effective alternative to the alcohol-based hand sanitizers became a necessity owning to the limitations associated with their use, such as skin dryness, irritant contact dermatitis, and intoxication upon their accidental ingestion...
August 2021: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/34249617/effect-of-sanitizer-on-obliteration-of-sars-cov2-covid-19-a-mini-review
#22
JOURNAL ARTICLE
V Andal, R Lakshmipathy, Deepa Jose
Corona virus is a respiratory virus which causes infectious Covid-19 (Corona Virus -2019) disease and globally the virus continues to pose major risks of mortality. It is lucid that close links are the key aspect for transitory of communicable Corona virus. Rapid research is in progress to identify prolific drugs and vaccine for Covid-19 however, it is a time consuming process. Social distancing and Sanitizers are helpful in combating virus and safeguarding the human health. Hand sanitizers are prolific when hands washing with soaps are not possible...
July 6, 2021: Materials Today: Proceedings
https://read.qxmd.com/read/34235774/patient-experiences-with-hidradenitis-suppurativa-the-hidradenitis-patient-experience-survey
#23
JOURNAL ARTICLE
N Kashetsky, I M Mukovozov, J Pereira, R Manion, S Carter, R Alhusayen
BACKGROUND: Better understanding the experience of people living with hidradenitis suppurativa (HS) is essential to identifying gaps in current patient care and informing healthcare decision making. OBJECTIVE: To describe the patient experience of individuals with HS, including their path to diagnosis, symptom control, treatments, healthcare utilization, patient needs, and impact on quality of life. METHODS: The Hidradenitis Suppurativa Patient Experience survey was created, extensively reviewed, and disseminated through engaging HS-related patient organizations, physician groups, and social media groups...
July 8, 2021: Clinical and Experimental Dermatology
https://read.qxmd.com/read/34103320/effectiveness-of-meatal-cleaning-in-the-prevention-of-catheter-associated-urinary-tract-infections-and-bacteriuria-an-updated-systematic-review-and-meta-analysis
#24
JOURNAL ARTICLE
Brett Mitchell, Cassie Curryer, Elizabeth Holliday, Claire M Rickard, Oyebola Fasugba
OBJECTIVE: A systematic review on meatal cleaning prior to urinary catheterisation and post catheterisation and reduces the risk catheter-associated urinary tract infections (CAUTIs) and bacteriuria was published in 2017, with further studies undertaken since this time. The objective of this paper is to present an updated systematic review on the effectiveness of antiseptic cleaning of the meatal area for the prevention of CAUTIs and bacteriuria in patients who receive a urinary catheter...
June 8, 2021: BMJ Open
https://read.qxmd.com/read/33669633/searching-for-small-molecules-as-antibacterials-non-cytotoxic-diarylureas-analogues-of-triclocarban
#25
JOURNAL ARTICLE
Alessia Catalano, Domenico Iacopetta, Antonio Rosato, Lara Salvagno, Jessica Ceramella, Francesca Longo, Maria Stefania Sinicropi, Carlo Franchini
Triclocarban (TCC), a broad-spectrum lipophilic antimicrobial agent, is a diarylurea derivative that has been used for more than 60 years as a major ingredient of toys, clothing, food packaging materials, food industry floors, medical supplies and especially of personal care products, such as soaps, toothpaste and shampoo. In September 2016, the U.S. FDA banned nineteen antimicrobial ingredients, including TCC, in over-the-counter consumer antiseptic wash products, due to their toxicity. Withdrawal of TCC has prompted efforts to search for new antimicrobial compounds...
February 19, 2021: Antibiotics
https://read.qxmd.com/read/33658274/evaluating-the-antimicrobial-properties-of-commercial-hand-sanitizers
#26
JOURNAL ARTICLE
M Chojnacki, C Dobrotka, R Osborn, W Johnson, M Young, B Meyer, E Laskey, R A F Wozniak, S Dewhurst, P M Dunman
Hand sanitizers have been developed as a convenient means to decontaminate an individual's hands of bacterial pathogens in situations in which soap and water are not available. Yet to our knowledge, no study has compared the antibacterial efficacy of a large collection of hand sanitizers. Using zone of growth inhibition and kill curve assays, we assessed the performance of 46 commercially available hand sanitizers that were obtained from national chain big-box stores, gasoline stations, pharmacies, and boutiques for antibacterial activity toward prototypical Gram-positive ( Staphylococcus aureus ) and Gram-negative ( Escherichia coli ) bacterial pathogens...
March 3, 2021: MSphere
https://read.qxmd.com/read/33571401/african-black-soap-physiochemical-phytochemical-properties-and-uses
#27
REVIEW
Adebola Ogunbiyi, Nkechi A Enechukwu
The African black soap is popular for its cleansing and medicinal properties particularly amongst those of African descent. The "traditional" African black soap" refers to soaps made from the ash derived alkali from agricultural waste and oil extracted from vegetable matter without the addition of cosmetic enhancing products. Production of black soap has been traced to west Africa especially Nigeria and Ghana. The raw materials are readily available in the region making the soap available and affordable for most in sub-Saharan Africa...
February 11, 2021: Dermatologic Therapy
https://read.qxmd.com/read/33299385/study-of-cold-pressed-tobacco-seed-oil-properties-by-gas-chromatography-method
#28
REVIEW
Murat Z Ashirov, Ubaidilla M Datkhayev, Diyas A Myrzakozha, Hidetoshi Sato, Kairat S Zhakipbekov, Nurgali A Rakhymbayev, Bolat N Sadykov
A special place among vegetable oils was occupied by natural tobacco oil. Natural tobacco oil in folk medicine is used as an antiseptic and antibacterial agent. To determine the possible alternative use of tobacco, the seeds representing Kazakhstan tobacco cultivars, extracted from ground Nicotiana tabacum seeds, were investigated by using the cold press. The quality of the oil was assessed in terms of free fatty acid content. The percentage oil yield was 36.75 ± 0.50%. Tobacco seed oil is highly unsaturated, nonacidic, and would require little purification...
2020: TheScientificWorldJournal
https://read.qxmd.com/read/33112328/synthesis-of-cationic-acrylate-copolyvidone-iodine-nanoparticles-with-double-active-centers-and-their-antibacterial-application
#29
JOURNAL ARTICLE
Xuemei Li, Bin Wang, Tingyu Liang, Rongmin Wang, Pengfei Song, Yufeng He
Antibacterial materials are rapidly emerging as a primary component in the mitigation of bacterial pathogens, and functional polymers play a vital role in the preparation of antibacterial coatings. In this study, a novel antibacterial polymer with double active centers was synthesized. Firstly, using one-pot soap-free emulsion polymerization technology, the cationic acrylate copolymeric polyvidone (CACPV) was synthesized by copolymerization of four monomers with different functions, which were methyl methacrylate (MMA), N-vinyl-2-pyrrolidone (NVP), γ-methacryloxypropyltrimethoxysilane (MAPTS) and [3-(methacryloylamino)propyl]trimethylammonium chloride (MAPTAC)...
November 5, 2020: Nanoscale
https://read.qxmd.com/read/32974119/influence-of-rosa-damascena-hydrosol-on-skin-flora-contact-culture-after-hand-rubbing
#30
JOURNAL ARTICLE
Gulsum Iclal Bayhan, Tulay Gumus, Basak Alan, Isil Kubra Savas, Saliha Aysenur Cam, Elif Ayca Sahin, Seyfullah Oktay Arslan
Aim and Introduction: Rosa damascena is one of the most well-known species of the Rosaceae family and is widely used in the food and perfume industry. Rose hydrosol is a product which is produced by distillation of rose petals. There is very little research about the antimicrobial effect of rose hydrosol. In this study, we aimed to investigate the antibacterial effect of Rosa damascena hydrosol in vivo . Method: 45 adult volunteers who were not healthcare workers were included in this study. Exclusion criteria included existing skin disorders or lacerations, pregnancy, presence of nail polish, recent handwashing or use of antiseptic lotion/soap in the last week, and antibiotic use in the last 3 months...
2020: GMS Hygiene and Infection Control
https://read.qxmd.com/read/32702547/environmental-side-effects-of-the-injudicious-use-of-antimicrobials-in-the-era-of-covid-19
#31
JOURNAL ARTICLE
Muhammad Usman, Muhammad Farooq, Khalil Hanna
Use of antimicrobials in the treatment and prevention of COVID-19, caused by novel coronavirus SARS-CoV-2, is on the rise. The increased use of antimicrobials can have serious consequences on the environment. Antibiotics have had a reasonable role in bacterial co-infections with regards to the management of COVID-19. However, recent evidences suggest that there has been injudicious prescription of antimicrobials. Moreover, a large number of people are self-medicating with antibiotics in a misguided attempt to protect themselves from the virus...
November 25, 2020: Science of the Total Environment
https://read.qxmd.com/read/32304807/examining-bacteria-on-skin-and-jewelry-since-the-implementation-of-hand-sanitizer-in-hospitals
#32
JOURNAL ARTICLE
Katrina Greenshield, Jennifer Chavez, Kelly Jo Nial, Kathleen Baldwin
Nurses currently disinfect their hands with antibacterial soap and hand sanitizer. This comparative, descriptive study evaluated skin bacteria at baseline and 30 days after jewelry removal in intensive care unit nurses. Identified bacteria species were: (1) Bacillus, (2) Micrococcus, (3) coagulase negative Staphylococcus, (4) Diphtheroid, ( 5) Streptococcus, and (6) nonenteric gram-negative rods. The majority of the bacteria was found on skin at baseline. Bacterial counts significantly decreased at 30 days.
November 2020: American Journal of Infection Control
https://read.qxmd.com/read/32099925/chemical-characterization-antioxidant-cytotoxicity-anti-toxoplasma-gondii-and-antimicrobial-potentials-of-the-citrus-sinensis-seed-oil-for-sustainable-cosmeceutical-production
#33
JOURNAL ARTICLE
O Atolani, N Adamu, O S Oguntoye, M F Zubair, O A Fabiyi, R A Oyegoke, O S Adeyemi, E T Areh, D E Tarigha, L Kambizi, G A Olatunji
There are growing concerns about the chronic and acute effects of synthetic additives such as antibacterial, fragrances, colourants and stabilizing agents used in the production of various household products. Many household products and materials including cosmetic products are reportedly suspected to be carcinogenic with some acting as endocrine disruptors among other effects. Thus, environmental-friendly alternatives such as products that are rich in bioactive phytochemicals are becoming consumers' preferred choice especially in the beauty and cosmetic sector...
February 2020: Heliyon
https://read.qxmd.com/read/31788715/in-vitro-metabolism-of-triclosan-studied-by-liquid-chromatography-high-resolution-tandem-mass-spectrometry
#34
JOURNAL ARTICLE
Amal Guesmi, Lekha Sleno
Triclosan (TCS) is an antibacterial and antifungal compound found in many hygiene products, including toothpaste, soap, and detergents. However, this molecule can act as an endocrine disruptor and can induce harmful effects on human health and the environment. In this study, triclosan was biotransformed in vitro using human and rat liver fractions, to evaluate oxidative metabolism, the formation of reactive metabolites via the detection of GSH adducts, as well as glucuronide and sulfate conjugates using liquid chromatography coupled to high-resolution tandem mass spectrometry (LC-HRMS/MS)...
December 1, 2019: Analytical and Bioanalytical Chemistry
https://read.qxmd.com/read/31767233/benzalkonium-chloride-alters-phenotypic-and-genotypic-antibiotic-resistance-profiles-in-a-source-water-used-for-drinking-water-treatment
#35
JOURNAL ARTICLE
Katherine R Harrison, Anthony D Kappell, Patrick J McNamara
Antibiotic resistance is a major public health concern. Triclosan is an antimicrobial compound with direct links to antibiotic resistance that was widely used in soaps in the U.S. until its ban by the U.S. Food and Drug Administration. Benzalkonium chloride (BAC), a quaternary ammonium compound, has widely replaced triclosan in soaps marketed as an antibacterial. BAC has been detected in surface waters and its presence will likely increase following increased use in soap products. The objective of this study was to determine the effect of BAC on relative abundance of antibiotic resistance in a bacterial community from a surface water used as a source for drinking water treatment...
October 26, 2019: Environmental Pollution
https://read.qxmd.com/read/31688130/triclosen-and-its-alternatives-in-antibacterial-soaps
#36
JOURNAL ARTICLE
Chandler W Rundle, Sophia Hu, Colby L Presley, Cory A Dunnick
BACKGROUND: In 2017, the Food and Drug Administration banned the marketing of triclosan and triclocarban in antibacterial soaps, citing inefficacy and concerns of systemic absorption and antibacterial resistance. As a result, there is an anticipated decrease in the number of triclosan-containing products on the market with an associated increase in antibacterial alternatives (eg, benzalkonium chloride, benzethonium chloride, chloroxylenol, chlorhexidine) and cases of allergic and irritant contact dermatitis...
November 2019: Dermatitis
https://read.qxmd.com/read/31572047/community-s-compliance-with-measures-for-the-prevention-of-respiratory-infections-in-riyadh-saudi-arabia
#37
JOURNAL ARTICLE
Ali M Alhazmi, Sulaiman A Alshammari, Hanan A Alenazi, Shaffi A Shaik, Hala M AlZaid, Nouf S Almahmoud, Hotoon S Alshammari
BACKGROUND: Acute respiratory tract infections are the most common causes of both morbidity and mortality worldwid, and the management and prevention of acute respiratory infections is a global problem, especially in developing countries. This study sought to assess the community's compliance and practice of measures for the prevention of respiratory infections and discover their source of health information. MATERIALS AND METHODS: A cross-sectional study was carried out in the five biggest shopping malls in Riyadh city in July 2014...
September 2019: Journal of Family & Community Medicine
https://read.qxmd.com/read/31182095/inhibitory-effects-of-azadirachta-indica-secondary-metabolites-formulated-cosmetics-on-some-infectious-pathogens-and-oxidative-stress-radicals
#38
JOURNAL ARTICLE
Sunday O Okoh, Omobola O Okoh, Anthony I Okoh
BACKGROUND: Infectious diseases, particularly those due to multi-drug resistant bacterial strains are almost impossible to cure globally. In this study we investigated the inhibitory effects of Azadirachta indica A. Juss secondary metabolites (AISM) formulated soap and cream for management of infectious and oxidative stress-related diseases (OSD). METHODS: The antibacterial, radical scavenging and cytotoxic effects of the neem cosmetics were examined by serial dilution, spectrophotometric and hemolytic techniques respectively, while the AISM in the essential oils (EOs) were elucidated by Gas chromatography-mass spectrometry (GC-MS) and retention index...
June 10, 2019: BMC Complementary and Alternative Medicine
https://read.qxmd.com/read/30859670/a-reduction-in-triclosan-and-triclocarban-in-water-resource-recovery-facilities-influent-effluent-and-biosolids-following-the-u-s-food-and-drug-administration-s-2013-proposed-rulemaking-on-antibacterial-products
#39
JOURNAL ARTICLE
Dominic A Brose, Kuldip Kumar, Anna Liao, Lakhwinder S Hundal, Guanglong Tian, Albert Cox, Heng Zhang, Edward W Podczerwinski
Pharmaceutical and personal care product compounds (PPCPs) comprise a large and diverse group of chemical compounds, including prescription and over-the-counter drugs and cleaning agents. Although PPCPs in the effluent and biosolids of water resource recovery facilities (WRRFs) are currently not regulated, public interest has led the Metropolitan Water Reclamation District of Greater Chicago to monitor for 11 PPCPs in the influent, effluent, and biosolids at its seven WRRFs. In 2016, the U.S. Food and Drug Administration (FDA) issued a final rule establishing that 19 specific ingredients, including triclosan and triclocarban, were no longer generally recognized as safe and effective, which prohibits companies from marketing soaps as antibacterial if they contain one or more of these ingredients...
August 2019: Water Environment Research: a Research Publication of the Water Environment Federation
https://read.qxmd.com/read/30661908/randomized-controlled-trial-evaluating-the-antimicrobial-efficacy-of-chlorhexidine-gluconate-and-para-chloro-meta-xylenol-handwash-formulations-in-real-world-doses
#40
JOURNAL ARTICLE
James W Arbogast, Lisa Bowersock, Albert J Parker, David R Macinga
Chlorhexidine gluconate-based soaps have become the gold standard for handwashing in critical care settings and para-chloro-meta-xylenol is an effective alternative antibacterial active ingredient. This study benchmarked 2 novel foaming handwashes, compared to a bland soap for antimicrobial effectiveness using the health care personnel handwash method at realistic soap doses (0.9 mL and 2.0 mL). To our knowledge, this is the first published efficacy study on realistic soap doses. Both soaps met Food and Drug Administration success criteria...
January 17, 2019: American Journal of Infection Control
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