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https://www.readbyqxmd.com/read/28213767/mountaintop-removal-coal-mining-and-emergent-cases-of-psychological-disorder-in-kentucky
#1
Will H Canu, John Paul Jameson, Ellen H Steele, Michael Denslow
Although mountaintop removal (MTR) coal extraction techniques have been employed in Appalachia for decades, relatively little research has examined its potential psychological impact on people living in close proximity to MTR activity. The current study taps the State Emergency Department Database (Healthcare Cost and Utilization Project, Kentucky State Emergency Department Database, 2008) to examine the relative risk for diagnoses of depressive, substance use, and anxiety disorders originating in areas with and without MTR activity...
February 17, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28202755/low-pathogenic-influenza-a-viruses-in-north-american-diving-ducks-contribute-to-the-emergence-of-a-novel-highly-pathogenic-influenza-a-h7n8-virus
#2
Yifei Xu, Andrew M Ramey, Andrew S Bowman, Thomas J DeLiberto, Mary L Killian, Scott Krauss, Jacqueline M Nolting, Mia Kim Torchetti, Andrew B Reeves, Richard J Webby, David E Stallknecht, Xiu-Feng Wan
Introductions of low pathogenic avian influenza (LPAI) viruses of subtypes H5 and H7 into poultry from wild birds have the potential to mutate to highly pathogenic avian influenza (HPAI), but such viruses' origins are often unclear. In January 2016, a novel H7N8 HPAI virus caused an outbreak in turkeys in Indiana, USA. To determine the virus's origin, we sequenced genomes of 441 wild bird-origin influenza A viruses (IAVs) from North America and subjected them to evolutionary analyses. Results showed that the H7N8 LPAI virus most likely circulated among diving ducks in the Mississippi flyway during autumn 2015 and was subsequently introduced to Indiana turkeys, in which it evolved high pathogenicity...
February 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28197863/characterization-of-foreign-born-vs-native-born-worker-fatalities-in-kentucky-2001-2014
#3
Yailet Cruz, Terry Lee Bunn, Nancy Hanner, Svetla Slavova
Information on foreign-born worker (FBW) and native-born worker (NBW) fatal injuries is scarce. The Kentucky Fatality Assessment and Control Evaluation program analyzed 2001-2014 worker fatality data. The Kentucky FBW fatality rate was double the US FBW and NBW rates, and 50% higher than the Kentucky NBW fatality rate. FBW average age at death was 38 years; NBW age was 47 years. FBW deaths occurred in construction (26%) and services (22%) industries, and transportation [28% (54% due to semi truck crashes)] and construction [26%(48% due to roofing, scaffolding, and ladder-related falls)] occupations; in contrast, NBW deaths occurred in services (22%), and transportation (18%) industries, and transportation (25%) and management (20%) occupations, and were due to exposures to inanimate mechanical forces (38%), and transport accidents (30%)...
February 15, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28165925/molecular-detection-of-candidatus-bartonella-mayotimonensis-in-north-american-bats
#4
Thomas M Lilley, Cali A Wilson, Riley F Bernard, Emma V Willcox, Eero J Vesterinen, Quinn M R Webber, Laura Kurpiers, Jenni M Prokkola, Imran Ejotre, Allen Kurta, Kenneth A Field, DeeAnn M Reeder, Arto T Pulliainen
Candidatus Bartonella mayotimonensis was detected in 2010 from an aortic valve sample of a patient with endocarditis from Iowa, the United States of America. The environmental source of the potentially new endocarditis-causing Bartonella remained elusive. We set out to study the prevalence and diversity of bat-associated Bartonella in North America. During 2015, mist nets and harp traps were used to capture 92 bats belonging to two species: little brown myotis (Myotis lucifugus Le Conte 1831, n = 73) and the gray myotis (M...
February 6, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28161300/development-and-delivery-of-a-pharmacist-training-program-to-increase-naloxone-access-in-kentucky
#5
Emma Palmer, Steve Hart, Patricia R Freeman
OBJECTIVE: To describe the development and delivery of a comprehensive training program for Kentucky pharmacists to enable dispensation of naloxone per protocol. PRACTICE DESCRIPTION: In May 2015, the Kentucky Board of Pharmacy (KBP) promulgated regulations outlining the requirements for pharmacists to initiate the dispensing of naloxone under a physician-approved protocol. The Advancing Pharmacy Practice in Kentucky Coalition, a partnership between Kentucky's Colleges of Pharmacy, KBP, and state and local pharmacists associations, developed and offered educational programming to fulfill this regulation...
February 1, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28160117/characterization-of-salmonella-spp-from-wastewater-used-for-food-production-in-morogoro-tanzania
#6
Ofred J Mhongole, Robinson H Mdegela, Lughano J M Kusiluka, Anita Forslund, Anders Dalsgaard
Wastewater use for crop irrigation and aquaculture is commonly practiced by communities situated close to wastewater treatment ponds. The objective of this study was to characterize Salmonella spp. and their antimicrobial susceptibility patterns among isolates from wastewater and Tilapia fish. A total of 123 Salmonella spp. isolates were isolated from 52 water and 21 fish intestinal samples. Genotyping of Salmonella spp. isolates was done by Pulsed-field Gel Electrophoresis (PFGE). Antimicrobial susceptibility testing was done by the minimal inhibitory concentration (MIC) technique...
March 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28145577/duodenojejunal-mesenteric-rents-survival-and-complications-after-surgical-correction-in-38-broodmares-2006-2014
#7
Shauna P Lawless, Laura A Werner, W True Baker, Robert J Hunt, Noah D Cohen
OBJECTIVES: To describe short-term and long-term survival of horses with duodenojejunal mesenteric rents, and to examine the association of selected preoperative, intraoperative, and postoperative factors with survival or colic after discharge, in horses with duodenojejunal mesenteric rents. STUDY DESIGN: Retrospective case series. ANIMALS: Horses undergoing surgery for correction of small intestinal lesions secondary to duodenojejunal mesenteric rents (n = 38)...
February 1, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28143718/comparative-efficacy-of-bilateral-thoracoscopic-splanchnicectomy-for-intractable-pain-secondary-to-pancreatic-cancer-vs-chronic-pancreatitis
#8
Neal Bhutiani, Gerald A Cheadle, Michael H Bahr, Gary C Vitale
BACKGROUND: Splanchnicectomy has been evaluated for treatment of chronic pain in both pancreatic cancer and chronic pancreatitis patients, though its efficacy has not been compared in these two patient populations. This study aims to compare bilateral thoracoscopic splanchnicectomy (BTS) in treatment of abdominal pain secondary to pancreatic cancer (PC) and chronic pancreatitis (CP). METHODS: A University of Louisville database was evaluated from July 1998 to March 2016 for patients undergoing BTS for intractable pain secondary to PC (n=48) or CP (n=75)...
January 28, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28140487/mccrearamycins-a-d-geldanamycin-derived-cyclopentenone-macrolactams-from-an-eastern-kentucky-abandoned-coal-mine-microbe
#9
Xiachang Wang, Yinan Zhang, Larissa V Ponomareva, Qingchao Qiu, Ryan Woodcock, Sherif I Elshahawi, Xiabin Chen, Ziyuan Zhou, Bruce E Hatcher, James C Hower, Chang-Guo Zhan, Sean Parkin, Madan K Kharel, S Randal Voss, Khaled A Shaaban, Jon S Thorson
Four cyclopentenone-containing ansamycin polyketides (mccrearamycins A-D), and six new geldanamycins (Gdms B-G, including new linear and mycothiol conjugates), were characterized as metabolites of Streptomyces sp. AD-23-14 isolated from the Rock Creek underground coal mine acid drainage site. Biomimetic chemical conversion studies using both simple synthetic models and Gdm D confirmed that the mccrearamycin cyclopentenone derives from benzilic acid rearrangement of 19-hydroxy Gdm, and thereby provides a new synthetic derivatization strategy and implicates a potential unique biocatalyst in mccrearamycin cyclopentenone formation...
January 31, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28139459/pharmacists-role-in-opioid-overdose-kentucky-pharmacists-willingness-to-participate-in-naloxone-dispensing
#10
Patricia R Freeman, Amie Goodin, SuZanne Troske, Audra Strahl, Amanda Fallin, Traci C Green
OBJECTIVES: To assess pharmacists' willingness to initiate the dispensing of naloxone. As of 2015, Kentucky law permits certified pharmacists to dispense naloxone under a physician-approved protocol. DESIGN: Electronic survey (e-mail) gauging perception of pharmacists' role in opioid overdose and attitudes toward, and barriers to, naloxone dispensing. SETTING AND PARTICIPANTS: All Kentucky pharmacists with active licenses in 2015. MAIN OUTCOME MEASURES: Ordinal logistic regression was used to estimate the impact of pharmacist characteristics and attitudes on willingness to initiate naloxone dispensing, where the dependent variable was operationalized as a Likert-type question on a scale of 1 (not at all willing) to 6 (very willing)...
January 28, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28137797/a-whole-genome-sequencing-approach-to-study-cefoxitin-resistant-salmonella-enterica-serovar-heidelberg-from-various-sources
#11
Romaine Edirmanasinghe, Rita Finley, E Jane Parmley, Brent P Avery, Carolee Carson, Sadjia Bekal, George Golding, Michael R Mulvey
This study characterized cefoxitin-resistant and susceptible Salmonella enterica serovar Heidelberg from human, abattoir poultry, and retail poultry to assess the molecular relationships of isolates from these sources in Québec in 2012. Isolates were collected as part of the Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS). All isolates were subjected to antimicrobial susceptibility testing, polymerase chain reaction (PCR) for CMY-2, pulsed-field gel electrophoresis (PFGE), and whole genome sequencing (WGS)...
January 30, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28137676/using-exploratory-data-analysis-to-identify-and-predict-patterns-of-human-lyme-disease-case-clustering-within-a-multistate-region-2010-2014
#12
Brian Hendricks, Miguella Mark-Carew
Lyme disease is the most commonly reported vectorborne disease in the United States. The objective of our study was to identify patterns of Lyme disease reporting after multistate inclusion to mitigate potential border effects. County-level human Lyme disease surveillance data were obtained from Kentucky, Maryland, Ohio, Pennsylvania, Virginia, and West Virginia state health departments. Rate smoothing and Local Moran's I was performed to identify clusters of reporting activity and identify spatial outliers...
February 2017: Spatial and Spatio-temporal Epidemiology
https://www.readbyqxmd.com/read/28130667/three-new-species-of-plagioporus-stafford-1904-from-darters-perciformes-percidae-with-a-redescription-of-plagioporus-boleosomi-pearse-1924-peters-1957
#13
Thomas J Fayton, Anindo Choudhury, Chris T McAllister, Henry W Robison
A form of Plagioporus Stafford, 1904 is described from the intestine of three North American species of darters (Perciformes: Percidae) from River West Twin, Wisconsin, USA, that we consider to be conspecific with Plagioporus boleosomi (Pearse, 1924) Peters, 1957 based on similarities in the sucker ratio, extent of the forebody, shape and position of the testes, vitellarium distribution and terminal genitalia. Three new species of Plagioporus are described from the intestine of darters as follows: Plagioporus fonti n...
February 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28130658/high-seroprevalence-of-toxoplasma-gondii-in-elk-cervus-canadensis-of-the-central-appalachians-usa
#14
John J Cox, Brittany Slabach, John T Hast, Sean M Murphy, Oliver C H Kwok, Jitender P Dubey
Toxoplasma gondii is an important protozoan parasite of mammals that impacts animal health and behavior. Although this parasite has been documented in several cervid species, including red deer (Cervus elaphus) in Europe, little is known about T. gondii impacts on the closely related North American counterpart, the elk (wapiti, Cervus canadensis), which has increased in number and expanded in range during the past century. We assessed seroprevalence of T. gondii antibodies using a modified agglutination test (MAT) (1:25 titer) and blood collected from 142 free-ranging elk in Kentucky, USA, where the species was reintroduced during 1997-2002 after over a century of absence...
January 27, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28125576/invasive-cancer-incidence-and-survival-united-states-2013
#15
S Jane Henley, Simple D Singh, Jessica King, Reda J Wilson, Mary Elizabeth O'Neil, A Blythe Ryerson
Although cancer represents many heterogeneous diseases, some cancer types share common risk factors. For example, conclusive evidence links cancer at multiple sites with tobacco use, alcohol use, human papillomavirus (HPV) infection, excess body weight, and physical inactivity (1,2). To monitor changes in cancer incidence and assess progress toward achieving Healthy People 2020 objectives,* CDC analyzed data from the U.S. Cancer Statistics (USCS) data set for 2013, the most recent year for which incidence and survival data are available...
January 27, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28124965/-bacteremia-caused-by-ciprofloxacin-resistant-salmonella-serotype-kentucky-a-case-report-and-the-review-of-literature
#16
Tuba Müderris, Fatma Yekta Ürkmez, Şeref Alp Küçüker, Muhammet Fethi Sağlam, Gül Ruhsar Yılmaz, Rahmet Güner, Revasiye Güleşen, Ziya Cibali Açıkgöz
Salmonella infections can be seen in four clinical types, namely gastroenteritis, bacteremia/sepsis, enteric fever and carriage. These infections can result in uncomplicated diarrhea in most cases, but can lead to invasive disease requiring antimicrobial therapy and can be life-threatening in elderly or immunocomprimised patients. Broad-spectrum cephalosporins and fluoroquinolones are crucial options in the treatment of the invasive infections. Ciprofloxacin resistance is rarely seen in non-typhoid Salmonella enterica isolates, and only in S...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28105330/genetic-markers-associated-with-resistance-to-beta-lactam-and-quinolone-antimicrobials-in-non-typhoidal-salmonella-isolates-from-humans-and-animals-in-central-ethiopia
#17
Tadesse Eguale, Josephine Birungi, Daniel Asrat, Moses N Njahira, Joyce Njuguna, Wondwossen A Gebreyes, John S Gunn, Appolinaire Djikeng, Ephrem Engidawork
BACKGROUND: Beta-lactam and quinolone antimicrobials are commonly used for treatment of infections caused by non-typhoidal Salmonella (NTS) and other pathogens. Resistance to these classes of antimicrobials has increased significantly in the recent years. However, little is known on the genetic basis of resistance to these drugs in Salmonella isolates from Ethiopia. METHODS: Salmonella isolates with reduced susceptibility to beta-lactams (n = 43) were tested for genes encoding for beta-lactamase enzymes, and those resistant to quinolones (n = 29) for mutations in the quinolone resistance determining region (QRDR) as well as plasmid mediated quinolone resistance (PMQR) genes using PCR and sequencing...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28102909/the-effects-of-hospital-characteristics-on-delays-in-breast-cancer-diagnosis-in-appalachian-communities-a-population-based-study
#18
Christopher J Louis, Jonathan R Clark, Marianne M Hillemeier, Fabian Camacho, Nengliang Yao, Roger T Anderson
PURPOSE: Despite being generally accepted that delays in diagnosing breast cancer are of prognostic and psychological concern, the influence of hospital characteristics on such delays remains poorly understood, especially in rural and underserved areas. However, hospital characteristics have been tied to greater efficiency and warrant further investigation as they may have implications for breast cancer care in these areas. METHODS: Study data were derived from the Kentucky, North Carolina, Ohio, and Pennsylvania state central cancer registries (2006-2008)...
January 19, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28100146/examining-the-relationship-between-childhood-victimization-high-risk-behaviors-and-health-among-criminal-justice-involved-women
#19
Tanya Renn, Seana Golder, George Higgins, T K Logan, Katherine M Winham
The purpose of this study was to develop and test a conceptual model of the pathways through which childhood victimization influences adult health outcomes. Specifically, measures of high-risk behaviors, tobacco use, alcohol use, illegal substance use, and HIV risk behaviors were hypothesized to mediate the relationship between childhood victimization and adult physical health. The sample consisted of 406 women on probation and parole with a history of childhood victimization in Jefferson County, Kentucky. Structural equation modeling was used to examine the relationship between childhood victimization, high-risk behaviors, and physical health outcomes...
January 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28093688/kentucky-health-access-nurturing-development-services-home-visiting-program-improves-maternal-and-child-health
#20
Corrine M Williams, Sarah Cprek, Ibitola Asaolu, Brenda English, Tracey Jewell, Kylen Smith, Joyce Robl
BACKGROUND AND OBJECTIVES: Home visitation programs are one of the numerous efforts to help reduce the rates of preterm birth and low birth weight as well as offering other improvements in maternal and child health and development. The Kentucky Health Access Nurturing Development Services (HANDS) is a voluntary, home visiting program serving first-time, high-risk mothers. This study's objective was to evaluate the impact of HANDS on maternal and child health outcomes. METHODS: HANDS administrative data, live birth certificate records and data from the Division of Child Protection and Safety were used in these analyses...
January 16, 2017: Maternal and Child Health Journal
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