Raphael Cauchois, Lea Pietri, Jean-Baptiste Dalmas, Marie Koubi, Thibaut Capron, Nadim Cassir, Nicola Potere, Ildo Polidoro, Rodolphe Jean, Pierre-André Jarrot, Baptiste Andre, Veronique Veit, Julien Carvelli, Vanessa Pauly, Pascal Chanez, Laurent Papazian, Gilles Kaplanski
During SARS-CoV-2 infection, eosinopenia may reflect a hyperactive immune response. In this study of hospitalized COVID-19 patients, we aimed to better understand the prognostic value of severe eosinopenia (absolute eosinophil count = 0 G/L) and decipher its underlying mechanisms. We retrospectively analyzed the records of COVID-19 patients hospitalized from March to June 2020 in three university hospitals in Marseille, France. We assessed the association between severe eosinopenia and a composite poor outcome in these patients, including the need for oxygen supplementation at >6 L/min, ICU admission, and in-hospital death...
December 7, 2022: Microorganisms