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Lung volume recruitment

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https://www.readbyqxmd.com/read/29670346/prediction-of-severe-exacerbations-and-mortality-in-copd-the-role-of-exacerbation-history-and-inspiratory-capacity-total-lung-capacity-ratio
#1
João Cardoso, Ricardo Coelho, Carla Rocha, Constança Coelho, Luísa Semedo, A Bugalho Almeida
Background: Severe exacerbations and mortality are major outcomes in COPD, and risk factors for these events are actively searched for. Several predictors of mortality have been identified in COPD. The inspiratory capacity/total lung capacity (IC/TLC) ratio has been shown to be a strong predictor of all cause and respiratory mortality in patients with COPD. The major objectives of this study were to analyze which clinical parameters, including lung volumes, were the best predictors of the 5-year cumulative risk of hospital admissions or death and the 5-year risk of exacerbations, in stable COPD patients...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29652760/influence-of-disease-severity-and-exercise-limitation-on-exercise-training-intensity-and-load-and-health-benefits-from-pulmonary-rehabilitation-in-patients-with-copd-an-exploratory-study
#2
Virginia C Huynh, Desi P Fuhr, Bradley W Byers, Anne-Marie Selzler, Linn E Moore, Michael K Stickland
PURPOSE: Some patients with chronic obstructive pulmonary disease (COPD) fail to achieve health benefits with pulmonary rehabilitation (PR). Exercise intensity and load represent stimulus for adaptation but it is unclear whether inappropriate exercise intensity and/or load are affected by severity of COPD, which may affect health benefits. The purpose was to determine whether COPD severity and/or the severity of pulmonary limitation to exercise (PLE) impacted exercising intensity or load and whether resultant intensity/load affected health outcomes derived from PR...
April 11, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29628587/effects-of-preoxygenation-with-tidal-volume-breathing-followed-by-apneic-oxygenation-with-and-without-continuous-positive-airway-pressure-on-duration-of-safe-apnea-time-and-arterial-blood-gases
#3
Sunil Rajan, Nandhini Joseph, Pulak Tosh, Jerry Paul, Lakshmi Kumar
Background: Application of continuous positive airway pressure (CPAP) helps to recruit collapsed areas of the lung, which improves the oxygen reserve. Aim of the Study: To compare the time to desaturate to 90% during apnea following preoxygenation and apneic ventilation with tidal volume breathing for 3 min with and without the application of CPAP. Settings and Design: This prospective randomized study was conducted in a tertiary care institution...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29617006/relevance-of-b-lines-on-lung-ultrasound-in-volume-overload-and-pulmonary-congestion-clinical-correlations-and-outcomes-in-patients-on-hemodialysis
#4
Marc M Saad, Jeanne Kamal, Elias Moussaly, Boutros Karam, Wissam Mansour, Emad Gobran, Saqib Hussen Abbasi, Ahmed Mahgoub, Puja Singh, Ross Hardy, Devjani Das, Cara Brown, Monica Kapoor, Seleshi Demissie, Morton J Kleiner, Elie El Charabaty, Suzanne E El Sayegh
BACKGROUND: Volume overload in patients on hemodialysis (HD) is an independent risk factor for cardiovascular mortality. B-lines detected on lung ultrasound (BLUS) assess extravascular lung water. This raises interest in its utility for assessing volume status and cardiovascular outcomes. METHODS: End-stage renal disease patients on HD at the Island Rehab Center being older than 18 years were screened. Patients achieving their dry weight (DW) had a lung ultrasound in a supine position...
November 29, 2017: Cardiorenal Medicine
https://www.readbyqxmd.com/read/29615226/effect-of-long-term-exposure-to-fine-particulate-matter-on-lung-function-decline-and-risk-of-chronic-obstructive-pulmonary-disease-in-taiwan-a-longitudinal-cohort-study
#5
Cui Guo, Zilong Zhang, Alexis K H Lau, Chang Qing Lin, Yuan Chieh Chuang, Jimmy Chan, Wun Kai Jiang, Tony Tam, Eng-Kiong Yeoh, Ta-Chien Chan, Ly-Yun Chang, Xiang Qian Lao
BACKGROUND: Information on the effects of long-term exposure to fine particulate matter with an aerodynamic diameter of 2·5 μm or less (PM2·5 ) on lung health is scarce. We aimed to investigate the associations between long-term exposure to PM2·5 , lung function, and chronic obstructive pulmonary disease (COPD) in a large-scale longitudinal cohort. METHODS: We included 285 046 participants aged 20 years or older from the Taiwan MJ Health Management Institution cohort, who were recruited between 2001 and 2014 and had spirometric tests during the medical examination visit...
March 2018: Lancet. Planetary Health
https://www.readbyqxmd.com/read/29609563/the-association-between-circulating-adiponectin-levels-lung-function-and-adiposity-in-subjects-from-the-general-population-data-from-the-akershus-sleep-apnea-project
#6
Nina F Caspersen, Helge Røsjø, Allan Flyvbjerg, Mette Bjerre, Anna Randby, Harald Hrubos-Strøm, Torbjørn Omland, Gunnar Einvik
BACKGROUND: Circulating adiponectin (ADPN) levels are inversely associated with disease severity in patients with chronic obstructive pulmonary disease (COPD), while studies assessing the relationship between ADPN and lung function in subjects from the general population have shown diverging results. Accordingly, we hypothesized that ADPN would be associated with lung function in a population-based sample and tested how abdominal adiposity, metabolic syndrome, and systemic inflammation influenced this association...
April 2, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29596290/use-of-recruitment-maneuvers-in-patients-with-acute-respiratory-distress-syndrome
#7
Angela Nguyen
Acute respiratory distress syndrome (ARDS) is a deadly complication in critically ill patients that causes significant morbidity and mortality. Patients with ARDS are seen across intensive care unit settings, with treatment being largely supportive involving techniques through mechanical ventilation. Using low-tidal-volume ventilation is a standard of practice for patients with ARDS, as a lung protection strategy; however, alveolar decruitment may occur. Recruitment maneuvers can recruit collapsed alveoli and promote oxygenation...
May 2018: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/29595185/acute-respiratory-distress-syndrome-challenge-for-diagnosis-and-therapy
#8
REVIEW
Chun Pan, Ling Liu, Jian-Feng Xie, Hai-Bo Qiu
Objective: Acute respiratory distress syndrome (ARDS) is a devastating clinical syndrome whose diagnosis and therapy are still in question. The aim of this review was to discuss the current challenge for the diagnosis and treatment of ARDS. Data Sources: Data sources were the published articles in English through December 2017 in PubMed using the following key words: "acute respiratory distress syndrome," "definition", "diagnosis," "therapy," "lung protective strategy," "right ventricular dysfunction," and "molecular mechanism...
March 27, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29553052/spirometric-reference-equations-for-elderly-chinese-in-jinan-aged-60-84-years
#9
Xin-Yu Tian, Chun-Hong Liu, De-Xiang Wang, Xiu-Li Ji, Hui Shi, Chun-Yan Zheng, Meng-Shuang Xie, Wei Xiao
Background: The interpretation of spirometry varies on different reference values. Older people are usually underrepresented in published predictive values. This study aimed at developing spirometric reference equations for elderly Chinese in Jinan aged 60-84 years and to compare them to previous equations. Methods: The project covered all of Jinan city, and the recruitment period lasted 9 months from January 1, 2017 to September 30, 2017, 434 healthy people aged 60-84 years who had never smoked (226 females and 208 males) were recruited to undergo spirometry...
March 19, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29549005/influence-of-dietary-nitrate-supplementation-on-lung-function-and-exercise-gas-exchange-in-copd-patients
#10
Mehrdad Behnia, Courtney M Wheatley, Alberto Avolio, Bruce D Johnson
BACKGROUND: During exercise as pulmonary blood flow rises, pulmonary capillary blood volume increases and gas exchange surface area expands through distention and recruitment. We have previously demonstrated that pulmonary capillary recruitment is limited in COPD patients with poorer exercise tolerance. Hypoxia and endothelial dysfunction lead to pulmonary vascular dysregulation possibly in part related to nitric oxide related pathways. PURPOSE: To determine if increasing dietary nitrate might influence lung surface area for gas exchange and subsequently impact exercise performance...
March 13, 2018: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29535516/relationship-between-the-presence-of-bronchiectasis-and-acute-exacerbation-in-thai-copd-patients
#11
Theerasuk Kawamatawong, Jitsupa Onnipa, Thitiporn Suwatanapongched
Background: The prevalence rate of bronchiectasis in COPD is variable. Coexisting bronchiectasis and COPD may influence COPD severity and exacerbation. Objective: We investigated whether bronchiectasis is associated with frequent or severe COPD exacerbation. Lower airway bacterial and mycobacterial infections are a possible mechanism for bronchiectasis. Materials and methods: A cross-sectional study was conducted in 2013-2014. COPD exacerbations and hospitalizations were reviewed...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29527842/different-pattern-of-chronic-obstructive-pulmonary-disease-assessment-test-score-between-chronic-bronchitis-and-non-chronic-bronchitis-patients
#12
Sang Hoon Yoo, Jae Ha Lee, Kwang Ha Yoo, Ki Suck Jung, Chin Kook Rhee
BACKGROUND: Chronic bronchitis (CB) is an important phenotype in chronic obstructive pulmonary disease (COPD). The purpose of this study is to evaluate different pattern of COPD assessment test (CAT) score between CB and non-CB patients. METHODS: Patients were recruited from 45 centers in Korea, as part of the Korean COPD Subgroup Study cohort. CB was defined when sputum continued for at least 3 months. RESULTS: Total 958 patients with COPD were eligible for analysis...
March 7, 2018: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29520071/hsp27-inhibitor-attenuates-radiation-induced-pulmonary-inflammation
#13
Jee-Youn Kim, Yong-Min An, Byeong Rok Yoo, Jin-Mo Kim, Song Yee Han, Younghwa Na, Yun-Sil Lee, Jaeho Cho
Radiation therapy has been used to treat over 70% of thoracic cancer; however, the method usually causes radiation pneumonitis. In the current study, we investigated the radioprotective effects of HSP27 inhibitor (J2) on radiation-induced lung inflammation in comparison to amifostine. In gross and histological findings, J2 treatment significantly inhibited immune cell infiltration in lung tissue, revealing anti-inflammatory potential of J2. Normal lung volume, evaluated by micro-CT analysis, in J2-treated mice was higher compared to that in irradiated mice...
March 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29505522/the-effects-of-one-lung-ventilation-mode-on-lung-function-in-elderly-patients-undergoing-esophageal-cancer-surgery
#14
RANDOMIZED CONTROLLED TRIAL
Bao-Juan Zhang, Hai-Tao Tian, Hai-Ou Li, Jian Meng
The objective of the present study was to explore the effects of different one-lung ventilation (OLV) modes on lung function in elderly patients undergoing esophageal cancer surgery. A total of 180 consecutive elderly patients (ASA Grades I-II, with OLV indications) undergoing elective surgery were recruited in the study. Patients were randomly divided into 4 groups (n = 45). In Group A, patients received low tidal volume (VT < 8 mL/kg) + pressure controlled ventilation (PCV), low tidal volume (VT < 8 mL/kg) + volume-controlled ventilation (VCV) in Group B, high tidal volume (VT ≥ 8 mL/kg) + PCV in Group C and high tidal volume (VT ≥ 8 mL/kg) + VCV in Group D...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29501246/favorable-association-of-polyphenol-rich-diets-with-lung-function-cross-sectional-findings-from-the-moli-sani-study
#15
George Pounis, Antonella Arcari, Simona Costanzo, Augusto Di Castelnuovo, Marialaura Bonaccio, Mariarosaria Persichillo, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
BACKGROUND: The association of the polyphenol content of human diet with pulmonary function is not yet fully understood. This study aims at evaluating the association of polyphenol consumption with lung function in a novel holistic approach. METHODS: A cross-sectional analysis of 4551 women and 5108 men (age ≥35 years) from the Moli-sani study was performed. Participants were randomly recruited from the general population. The EPIC-FFQ was used for the dietary assessment...
March 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29498799/does-the-severity-of-interstitial-lung-disease-affect-the-gains-from-pulmonary-rehabilitation
#16
Sami Deniz, Hülya Şahin, Enver Yalnız
INTRODUCTION: Reduced exercise capacity is a main feature of Interstitial Lung Diseases (ILDs) and it is related to closely prognosis of these patients. Pulmonary Rehabilitation (PR) results to improve in peak exercise capacity, dyspnea and quality of life in ILDs. OBJECTIVES: We aimed to evaluate the benefits of PR in patients with ILDs and to determine whether there are similar gains in patients with severe ILD. METHODS: We recruited ILD stable patients...
March 2, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29488205/copd-course-and-comorbidities-are-there-gender-differences
#17
Marcin Grabicki, Barbara Kuźnar-Kamińska, Renata Rubinsztajn, Beata Brajer-Luftmann, Monika Kosacka, Agata Nowicka, Tomasz Piorunek, Magdalena Kostrzewska, Ryszarda Chazan, Halina Batura-Gabryel
The prevalence of chronic obstructive pulmonary disease (COPD) has increased more rapidly in women than in men during the past two decades. Clinical presentation, comorbidities and prognosis may differ between genders and may influence management decisions. The influence of gender on COPD expression has not been clearly explained to date. Thus, the aim of this study was to evaluate significant differences between women and men suffering from COPD, regarding clinical presentation, pulmonary function test results, comorbidities, and prognosis...
February 28, 2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29485340/incentive-spirometry-and-positive-expiratory-pressure-improve-ventilation-and-recruitment-in-postoperative-recovery-a-randomized-crossover-study
#18
Gregory Reychler, Valeska Uribe Rodriguez, Cheryl Elizabeth Hickmann, Bertrand Tombal, Pierre-François Laterre, Axel Feyaerts, Jean Roeseler
INTRODUCTION: Impairment of global and regional pulmonary ventilations is a well-known consequence of general anesthesia. Positive expiratory pressure (PEP) or incentive spirometry (IS) is commonly prescribed, albeit their efficacy is poorly demonstrated. The aim of this study was to assess the effects of PEP and IS on lung ventilation and recruitment in patients after surgery involving anesthesia using electrical impedance tomography (EIT). METHOD: Ten male subjects (age = 61...
February 27, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29475456/detection-of-inspiratory-recruitment-of-atelectasis-by-automated-lung-sound-analysis-as-compared-to-four-dimensional-computed-tomography-in-a-porcine-lung-injury-model
#19
Stefan Boehme, Frédéric P R Toemboel, Erik K Hartmann, Alexander H Bentley, Oliver Weinheimer, Yang Yang, Tobias Achenbach, Michael Hagmann, Eugenijus Kaniusas, James E Baumgardner, Klaus Markstaller
BACKGROUND: Cyclic recruitment and de-recruitment of atelectasis (c-R/D) is a contributor to ventilator-induced lung injury (VILI). Bedside detection of this dynamic process could improve ventilator management. This study investigated the potential of automated lung sound analysis to detect c-R/D as compared to four-dimensional computed tomography (4DCT). METHODS: In ten piglets (25 ± 2 kg), acoustic measurements from 34 thoracic piezoelectric sensors (Meditron ASA, Norway) were performed, time synchronized to 4DCT scans, at positive end-expiratory pressures of 0, 5, 10, and 15 cmH2 O during mechanical ventilation, before and after induction of c-R/D by surfactant washout...
February 24, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29470939/free-breathing-pulmonary-mr-imaging-to-quantify-regional-ventilation
#20
Dante P I Capaldi, Rachel L Eddy, Sarah Svenningsen, Fumin Guo, John S H Baxter, A Jonathan McLeod, Parameswaran Nair, David G McCormack, Grace Parraga
Purpose To measure regional specific ventilation with free-breathing hydrogen 1 (1 H) magnetic resonance (MR) imaging without exogenous contrast material and to investigate correlations with hyperpolarized helium 3 (3 He) MR imaging and pulmonary function test measurements in healthy volunteers and patients with asthma. Materials and Methods Subjects underwent free-breathing1 H and static breath-hold hyperpolarized3 He MR imaging as well as spirometry and plethysmography; participants were consecutively recruited between January and June 2017...
February 22, 2018: Radiology
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