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https://www.readbyqxmd.com/read/28931203/scalpel-versus-electrosurgery-for-major-abdominal-incisions
#1
REVIEW
Kittipat Charoenkwan, Zipporah Iheozor-Ejiofor, Kittipan Rerkasem, Elizabeth Matovinovic
BACKGROUND: Scalpels or electrosurgery can be used to make abdominal incisions. The potential benefits of electrosurgery may include reduced blood loss, dry and rapid separation of tissue, and reduced risk of cutting injury to surgeons. Postsurgery risks possibly associated with electrosurgery may include poor wound healing and complications such as surgical site infection. OBJECTIVES: To assess the effects of electrosurgery compared with scalpel for major abdominal incisions...
June 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28931087/microbial-analysis-of-zetaproteobacteria-and-co-colonizers-of-iron-mats-in-the-troll-wall-vent-field-arctic-mid-ocean-ridge
#2
Jan Vander Roost, Ingunn Hindenes Thorseth, Håkon Dahle
Over the last decade it has become increasingly clear that Zetaproteobacteria are widespread in hydrothermal systems and that they contribute to the biogeochemical cycling of iron in these environments. However, how chemical factors control the distribution of Zetaproteobacteria and their co-occurring taxa remains elusive. Here we analysed iron mats from the Troll Wall Vent Field (TWVF) located at the Arctic Mid-Ocean Ridge (AMOR) in the Norwegian-Greenland Sea. The samples were taken at increasing distances from high-temperature venting chimneys towards areas with ultraslow low-temperature venting, encompassing a large variety in geochemical settings...
2017: PloS One
https://www.readbyqxmd.com/read/28931060/isolated-positive-anti-ss-b-autoantibodies-are-not-related-to-clinical-features-of-systemic-autoimmune-diseases-results-from-a-routine-population-survey
#3
Sabine Jardel, Nicole Fabien, Arnaud Hot, Sandra Vukusic, Jacques Tebib, Vincent Cottin, Pascal Sève, Maurice Laville, Alexandre Belot, Isabelle Durieu, Lorna Garnier, Frédéric Coutant, Quitterie Reynaud, Jean Christophe Lega
OBJECTIVE: To assess in clinical practice the frequency and diagnosis associated with the SS-B-positive/SS-A negative autoantibody profile. METHODS: We analyzed a one-year consecutive population of 624 patients referred by clinicians to the immunology laboratory to investigate anti-SS-A and/or anti-SS-B autoantibodies, who were detected using luminex technology. Data were analyzed for patients with isolated anti-SS-B autoantibodies. The clinical characteristics and diagnosis of connective tissue diseases (CTD) were retrieved according to the international criteria...
2017: PloS One
https://www.readbyqxmd.com/read/28931023/parsimonious-data-how-a-single-facebook-like-predicts-voting-behavior-in-multiparty-systems
#4
Jakob Bæk Kristensen, Thomas Albrechtsen, Emil Dahl-Nielsen, Michael Jensen, Magnus Skovrind, Tobias Bornakke
This study shows how liking politicians' public Facebook posts can be used as an accurate measure for predicting present-day voter intention in a multiparty system. We highlight that a few, but selective digital traces produce prediction accuracies that are on par or even greater than most current approaches based upon bigger and broader datasets. Combining the online and offline, we connect a subsample of surveyed respondents to their public Facebook activity and apply machine learning classifiers to explore the link between their political liking behaviour and actual voting intention...
2017: PloS One
https://www.readbyqxmd.com/read/28931009/ndfip-allows-nedd4-nedd4l-induced-aqp2-ubiquitination-and-degradation
#5
Christiane Trimpert, Daniel Wesche, Theun de Groot, Martha M Pimentel Rodriguez, Victoria Wong, Dennis T M van den Berg, Lydie Cheval, Carolina A Ariza, Alain Doucet, Igor Stagljar, Peter M T Deen
Regulation of our water homeostasis is fine-tuned by dynamic translocation of Aquaporin-2 (AQP2)-bearing vesicles to and from the plasma membrane of renal principal cells. Whereas binding of vasopressin to its type-2 receptor initiates a cAMP-protein kinase A cascade and AQP2 translocation to the apical membrane, this is counteracted by protein kinase C-activating hormones, resulting in ubiquitination-dependent internalization of AQP2. The proteins targeting AQP2 for ubiquitin-mediated degradation are unknown...
2017: PloS One
https://www.readbyqxmd.com/read/28930984/high-fat-diet-feeding-and-high-throughput-triacylglyceride-assay-in-drosophila-melanogaster
#6
Soda Balla Diop, Ryan T Birse, Rolf Bodmer
Heart disease is the number one cause of human death worldwide. Numerous studies have shown strong connections between obesity and cardiac malfunction in humans, but more tools and research efforts are needed to better elucidate the mechanisms involved. For over a century, the genetically highly tractable model of Drosophila has been instrumental in the discovery of key genes and molecular pathways that proved to be highly conserved across species. Many biological processes and disease mechanisms are functionally conserved in the fly, such as development (e...
September 13, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28930889/the-burden-of-mental-illness-among-veterans-use-of-vha-health-care-services-by-those-with-service-connected-conditions
#7
Charles Maynard, Adam Batten, Chuan-Fen Liu, Karin Nelson, Stephan D Fihn
BACKGROUND: Little is known about how Veterans with service-connected conditions use health care provided by the Veterans Health Administration (VHA). OBJECTIVES: To ascertain what proportion of Veterans with service-connected conditions used VHA health care and whether it varied according to type of condition, combined disability rating, age, sex, military rank, or other characteristics and whether there were differences in receipt of inpatient and outpatient care...
September 19, 2017: Medical Care
https://www.readbyqxmd.com/read/28930831/accessory-spleen-located-in-the-right-parietal-peritoneum-the-first-case-report
#8
Shao-Yan Xu, Ke Sun, Hai-Yang Xie, Lin Zhou, Shu-Sen Zheng, Weilin Wang
RATIONALE: Accessory spleen is a congenital abnormality caused by failure of the splenic anlage to fuse during embryology. The presence of an accessory spleen located in the parietal peritoneum has not been reported so far, and an accessory spleen situated on the right side is extremely rare. In the present study, we describe the first case of an accessory spleen located in the right parietal peritoneum. PATIENTS CONCERNS: A 65-year-old man, presented with pain in his left abdomen for 1 month...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930779/inhibition-of-lymphatic-drainage-with-a-self-designed-surgical-approach-prolongs-the-vascularized-skin-allograft-survival-in-rats
#9
Jiaomiao Pei, Yang Li, Chen Chen, Xi Zhang, Shiping Wang, Yajuan Song, Bei Liu, Yingjun Su, Shuzhong Guo
Vascularized composite allotransplantation (VCA) is an emerging treatment for significant tissue defects. However, VCAs usually consist of multiple highly antigenic skin tissues. Previous studies have shown that the lymphatic system in skin plays important roles in the initiation of immune responses during acute rejection, by transporting T cells and antigen-presenting dendritic cells to regional lymph nodes. Therefore, we designed a new surgical treatment to inhibit lymphatic drainage of skin allografts and investigated whether this approach could promote the survival of allografts and suppress immunological events after transplantation...
September 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28930562/alzheimer-s-disease-diagnostics-by-a-3d-deeply-supervised-adaptable-convolutional-network
#10
Ehsan Hosseini-Asl, Mohammed Ghazal, Ali Mahmoud, Ali Aslantas, Ahmed M Shalaby, Manual F Casanova, Gregory N Barnes, Georgy Gimel'farb, Robert Keynton, Ayman El-Baz
Early diagnosis is playing an important role in preventing progress of the Alzheimer's disease (AD). This paper proposes to improve the prediction of AD with a deep 3D Convolutional Neural Network (3D-CNN), which can show generic features capturing AD biomarkers extracted from brain images, adapt to different domain datasets, and accurately classify subjects with improved fine-tuning method. The 3D-CNN is built upon a convolutional autoencoder, which is pre-trained to capture anatomical shape variations in structural brain MRI scans for source domain...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28930543/eeg-and-erp-biomarkers-of-alzheimer-s-disease-a-critical-review
#11
Andras Horvath, Anna Szucs, Gabor Csukly, Anna Sakovics, Gabor Stefanics, Anita Kamondi
Here we critically review studies that used electroencephalography (EEG) or event-related potential (ERP) indices as a biomarker of Alzheimer's disease. In the first part we overview studies that relied on visual inspection of EEG traces and spectral characteristics of EEG. Second, we survey analysis methods motivated by dynamical systems theory (DST) as well as more recent network connectivity approaches. In the third part we review studies of sleep.  Next, we compare the utility of early and late ERP components in dementia research...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28930540/electrophysiological-evidence-for-long-axis-intrinsic-diversification-of-the-hippocampus
#12
Costas Papatheodoropoulos
The elongated structure of the hippocampus is critically involved in brain functions of profound importance. The segregation of functions along the longitudinal (septotemporal or dorsoventral) axis of the hippocampus is a slowly developed concept and currently is a widely accepted idea. The segregation of neuroanatomical connections along the hippocampal long axis can provide a basis for the interpretation of the functional segregation. However, an emerging and growing body of data strongly suggests the existence of endogenous diversification in the properties of the local neural network along the long axis of the hippocampus...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28930523/the-evolving-concept-of-the-intrinsic-hippocampal-theta-gamma-oscillator
#13
Mauro Cataldi, Chiara Vigliotti
  Three main types of electrical oscillations are recorded from the hippocampus in vivo: theta (θ), gamma (γ) and sharp wave ripples with frequency bands of 4-12, 25-100 and 110-250 Hz, respectively. Theta activity is the more robust of them, and has important physiological roles because it is involved in spatial navigation, memory formation and memory retrieval. Classical lesion studies in vivo have suggested that the hippocampus passively follows the θ  rhythm generated in the septum by neurons that are synaptically connected with hippocampal neurons though septo-hippocampal connections...
January 1, 2018: Frontiers in Bioscience (Scholar Edition)
https://www.readbyqxmd.com/read/28930471/possible-way-to-study-cononsolvency-in-confinement-lattice-density-functional-theory-approach
#14
Xueqian Chen, Wei Feng, Xia Han, Honglai Liu
The polymer lattice density functional theory (PLDFT) is used to investigate the cononsolvency (CNS) phenomena related to polymer adsorption in a slit pore. Specifically, two simplest types of CNS are examined: CNS1 with solvent-cosolvent binding as the dominate factor and CNS2 with polymer-cosolvent binding as the dominate factor. The simplified models for CNS1/CNS2 well capture the symmetrical/asymmetrical reentrant swelling transition of polymers positively/negatively adsorbed on the solid surface as confirmed by the calculation of PLDFT...
September 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28930449/o2-reduction-in-enzymatic-biofuel-cells
#15
Nicolas Mano, Anne de Poulpiquet
Catalytic four-electron reduction of O2 to water is one of the most extensively studied electrochemical reactions due to O2 exceptional availability and high O2/H2O redox potential, which may in particular allow highly energetic reactions in fuel cells. To circumvent the use of expensive and inefficient Pt catalysts, multicopper oxidases (MCOs) have been envisioned because they provide efficient O2 reduction with almost no overpotential. MCOs have been used to elaborate enzymatic biofuel cells (EBFCs), a subclass of fuel cells in which enzymes replace the conventional catalysts...
September 20, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28930432/injectable-stem-cell-laden-open-porous-microgels-that-favour-adipogenesis-in-vitro-and-in-vivo-evaluation
#16
Pengfei Xia, Kunxi Zhang, Yan Gong, Guifei Li, Shifeng Yan, Jingbo Yin
Microgels, with large surface area per volume, show great advantages in adipose tissue engineering due to their injectability and similarity with natural extracellular matrix. However, to date, no studies have tried applying microgels to adipose tissue regeneration. Herein, based on double bonded poly-(L-glutamic acid)-g-2-Hydroxyethyl methacrylate (PLGA-g-HEMA) and maleic anhydride-modified chitosan (MCS), an open porous microgel with high hydrophilicity and great injectability is successfully prepared (microgels diameter of 200-300 μm, pore diameter of 38 μm, and porosity of 88...
September 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28930381/intraocular-pressure-and-big-bubble-diameter-in-deep-anterior-lamellar-keratoplasty-an-ex-vivo-microscope-integrated-oct-with-heads-up-display-study
#17
Paramjit K Bhullar, Oscar M Carrasco-Zevallos, Alexandria Dandridge, Neel D Pasricha, Brenton Keller, Liangbo Shen, Joseph A Izatt, Cynthia A Toth, Anthony N Kuo
PURPOSE: To investigate the relationship between intraocular pressure (IOP) and big bubble (BB) formation in a model of deep anterior lamellar keratoplasty (DALK). DESIGN: Ex-vivo. METHODS: Corneoscleral buttons from human donors were loaded onto an artificial anterior chamber connected to a column of balanced salt solution. A surgeon-in-training learned to perform DALK via the BB technique using swept-source microscope-integrated optical coherence tomography (SS-MIOCT) with heads-up display (HUD)...
September 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28930377/epigenetics-the-future-direction-in-systemic-sclerosis
#18
REVIEW
M Walczyk, A Paradowska-Gorycka, M Olesinska
Systemic sclerosis (SSc) is an immune-mediated connective tissue disease of which the aetiology is still unclear. Previous genetic studies including candidate-gene studies and genomewide association studies have identified a number of genetic variations that confer risk to SSc. However, these variants, such as single nucleotide polymorphisms, cannot completely explain the SSc susceptibility and the diversity in the clinical symptoms of SSc patients. The contribution of epigenetic mechanisms as a link between genetics and environmental triggers represents promising field in understanding the pathogenesis of SSc...
August 21, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28930347/a-paper-triboelectric-nanogenerator-for-self-powered-electronic-systems
#19
Yanchao Mao, Nan Zhang, Yingjie Tang, Meng Wang, Mingju Chao, Erjun Liang
Paper, as one of the most important inventions of mankind, is still widely used in our daily life. In this study, the paper is explored as a platform for power sources based on the universally known triboelectric friction. A novel paper triboelectric nanogenerator (P-TENG) was successfully developed, which could harvest mechanical energy from ambient sources and generate considerable electrical energy. The maximum power density of the P-TENG reached 53 W m(-2). In addition, the P-TENG possesses a natural advantage of being able to be integrated within a book, and thus can effectively convert mechanical energy from the action of turning book pages into electricity...
September 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28930145/to-wnt-or-lose-the-missing-non-coding-linc-in-colorectal-cancer
#20
REVIEW
Peng Shen, Martin Pichler, Meng Chen, George A Calin, Hui Ling
Colorectal cancer (CRC) is the third most frequent cancer and one of the leading causes for cancer-related mortality. Aberrant activation of the Wnt signaling is an essential initiating factor in colon carcinogenesis, and a driving force of CRC progression. Recently, long non-coding RNAs (lncRNAs) have emerged as significant players in CRC pathogenesis through diversified mechanisms. Although both Wnt signaling and lncRNAs represent interesting research areas for CRC, an effort of directly connecting these two areas is lacking...
September 20, 2017: International Journal of Molecular Sciences
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