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https://www.readbyqxmd.com/read/28231685/unmet-psychosocial-needs-in-adolescents-with-inflammatory-bowel-disease
#1
(no author information available yet)
BACKGROUND: Inflammatory bowel diseases (IBD) are severe medical conditions with adverse impact on the quality of life of both children and their caregivers. IBD are associated with many limitations in personal and interpersonal functioning, and it also restricts the patients' ability to use the full potential (extent) of their capabilities. With the progress and humanization in society, the issue of patients' needs became an important topic; however, the psychosocial functioning and quality of life of adolescents suffering from IBD and their caregivers have been understudied...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231682/unmet-needs-of-the-patients-with-obsessive-compulsive-disorder
#2
(no author information available yet)
BACKGROUND: Obsessive compulsive disorder (OCD) is a disabling mental disorder with the chronic and difficult course. The disorder is accompanied by numerous limitations in personal and interpersonal functioning. OCD decreases the quality of life and the chance to maintain relationships and professional status. The patients with OCD often experience a severe disabling course of the disorder. Even the individuals, who follow treatment advice, are often still highly symptomatic. In the last decade, the concept of the needs has been assessed as an extent of the traditional outcome evaluation in order to focus on the identification of the specific needs of the patients and their relatives, improve the patients´ overall mental condition and quality of life, and also to increase the treatment effectiveness of the mental disorders...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231619/connective-tissue-graft-and-tunnel-or-trapezoidal-flap-for-the-treatment-of-single-maxillary-gingival-recessions-a-randomized-clinical-trial
#3
Mauro Pedrine Santamaria, Felipe Lucas da Silva Neves, Camila Augusto Silveira, Ingrid Fernandes Mathias, Stephanie Botti Fernandes-Dias, Maria Aparecida Neves Jardini, Dimitris N Tatakis
BACKGROUND: Although ample evidence supports connective tissue graft (CTG) use for root coverage, there is need for research on recipient site preparation approaches. The purpose of this study was to compare the outcomes of trapezoidal coronally advanced flap (CAF) and coronally advanced tunnel flap (TUN) when used in conjunction with CTG. METHODS: Forty-two patients presenting 42 single maxillary, Miller Class I and II, gingival recession defects were randomly assigned to receive either CAF+CTG (N=21) or TUN+CTG (N=21)...
February 23, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28231568/fiber-connections-of-the-caudal-corpus-cerebelli-with-special-reference-to-the-intrinsic-circuitry-in-a-teleost-oreochromis-niloticus
#4
Kosuke Imura, Naoyuki Yamamoto, Masami Yoshimoto, Masato Endo, Kengo Funakoshi, Hironobu Ito
The caudal part of the corpus cerebelli of Nile tilapia can be divided into dorsal and ventral regions. The granule cell layer of the dorsal (dGL) and ventral (vGL) regions of the caudal corpus cerebelli is known to receive indirect inputs from the telencephalon relayed by the nucleus paracommissuralis. The descending pathways are topographically organized, and the dGL and vGL receive inputs from different dorsal telencephalic parts. The caudal corpus cerebelli, in turn, projects extracerebellar efferents. However, it remains unknown how the descending telencephalic inputs are processed within the cerebellum...
February 24, 2017: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/28231480/feasibility-and-acceptability-of-post-hospitalization-ecological-momentary-assessment-in-patients-with-psychotic-spectrum-disorders
#5
Ethan Moitra, Brandon A Gaudiano, Carter H Davis, Dror Ben-Zeev
BACKGROUND: Up to 50% of patients with psychotic-spectrum disorders are medication nonadherent. The use of real-time assessment via ecological momentary assessment (EMA) on mobile devices might offer important insights into adherence behaviors that cannot be measured in the clinic. However, existing EMA studies have only studied acutely ill patients during hospitalization or more stable patients in the community. METHODS: Feasibility and acceptability of EMA in 65 patients with psychotic-spectrum disorders who were recently discharged from the hospital were assessed...
February 7, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28231458/gate-control-theory-springs-a-leak
#6
Paula J S Pereira, Ethan A Lerner
Sun and colleagues (2017) find that individual Grp+ spinal interneurons can respond to and distinguish between stimuli that provoke itch or pain. The nociceptive response is limited by enkaphalin-expressing interneurons that are connected synaptically to the Grp+ neurons.
February 22, 2017: Neuron
https://www.readbyqxmd.com/read/28231395/functional-connectivity-in-amygdalar-sensory-pre-motor-networks-at-rest-new-evidence-from-the-human-connectome-project
#7
Nicola Toschi, Andrea Duggento, Luca Passamonti
The word "e-motion" derives from the Latin word "ex-moveo" which literally means "moving away from something / somebody". Emotions are thus fundamental to prime action and goal-directed behavior with obvious implications for individual's survival. However, the brain mechanisms underlying the interactions between emotional and motor cortical systems remain poorly understood. A recent diffusion tensor imaging study in humans has reported the existence of direct anatomical connections between the amygdala and sensory/(pre)motor cortices, corroborating an initial observation in animal research...
February 23, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28231347/histomorphometric-results-after-postextraction-socket-healing-with-different-biomaterials-a-systematic-review-of-the-literature-and-meta-analysis
#8
Stefano Corbella, Silvio Taschieri, Luca Francetti, Roberto Weinstein, Massimo Del Fabbro
PURPOSE: The aim of this systematic review was to investigate which material is the most effective bone substitute for alveolar bone healing by evaluating histomorphometric outcomes after healing of postextraction sockets in humans. MATERIALS AND METHODS: A manual and electronic search (PubMed, EMBASE, Cochrane Library) was performed using a search string prepared ad hoc. Data were statistically analyzed by calculating weighted mean percentage of new bone formation (primary outcome) and weighted mean percentage of residual biomaterial, soft/connective tissue, and nonmineralized tissue (secondary outcomes) in the biopsies...
February 23, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28231345/in-vitro-evaluation-of-three-methods-for-the-retrieval-of-fractured-screw-fragments-from-dental-implants
#9
Rubén Agustín-Panadero, Carlos Labaig-Rueda, Beatriz Castillo-Rodriguez, Alberto Ferreiroa, María Fernanda Solá-Ruíz
PURPOSE: To compare the effectiveness of different methods of fractured screw fragment retrieval from dental implants, comparing a conventional method (use of an exploration probe and ultrasonic tips) with two mechanical retrieval kits. MATERIALS AND METHODS: One hundred thirty-five screws in implant internal connections were fractured to test fragment retrieval comparing three methods: conventional method with the use of an explorer probe and ultrasonic tips (group CE), extraction with a mechanical kit with a guide cylinder (group MK1), and extraction with a mechanical kit without a guide cylinder (group MK2)...
February 23, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28231324/a-framework-for-analyzing-contagion-in-assortative-banking-networks
#10
Thomas R Hurd, James P Gleeson, Sergey Melnik
We introduce a probabilistic framework that represents stylized banking networks with the aim of predicting the size of contagion events. Most previous work on random financial networks assumes independent connections between banks, whereas our framework explicitly allows for (dis)assortative edge probabilities (i.e., a tendency for small banks to link to large banks). We analyze default cascades triggered by shocking the network and find that the cascade can be understood as an explicit iterated mapping on a set of edge probabilities that converges to a fixed point...
2017: PloS One
https://www.readbyqxmd.com/read/28231296/cooperation-decision-time-and-culture-online-experiments-with-american-and-indian-participants
#11
Akihiro Nishi, Nicholas A Christakis, David G Rand
Two separate bodies of work have examined whether culture affects cooperation in economic games and whether cooperative or non-cooperative decisions occur more quickly. Here, we connect this work by exploring the relationship between decision time and cooperation in American versus Indian subjects. We use a series of dynamic social network experiments in which subjects play a repeated public goods game: 80 sessions for a total of 1,462 subjects (1,059 from the United States, 337 from India, and 66 from other countries) making 13,560 decisions...
2017: PloS One
https://www.readbyqxmd.com/read/28230898/manifestations-and-medicolegal-significance-of-loeys-dietz-syndrome
#12
Roger W Byard
Loeys-Dietz syndrome is a recently described autosomal dominant disorder with underlying vasculopathy characterized by aortic and other vascular aneurysmal dissection/rupture. A 61-year-old man is reported who died suddenly and unexpectedly and at autopsy was found to have a ruptured abdominal aortic aneurysm. Additional findings included dolichostenomelia, high-arched palate, and pectus excavatum. There was a strong family history of Loeys-Dietz syndrome, although the decedent had never been tested. Death was, therefore, due to a ruptured abdominal aortic aneurysm in a case of probable Loeys-Dietz syndrome...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28230860/carma2sh-and-ulk2-control-pathogen-associated-molecular-patterns-recognition-in-human-keratinocytes-psoriasis-linked-carma2sh-mutants-escape-ulk2-censorship
#13
Ivan Scudiero, Pellegrino Mazzone, Luca E D'Andrea, Angela Ferravante, Tiziana Zotti, Gianluca Telesio, Gabriele De Rubis, Carla Reale, Maddalena Pizzulo, Shanmugakonar Muralitharan, Pasquale Vito, Romania Stilo
The molecular complexes formed by specific members of the family of CARMA proteins, the CARD domain-containing adapter molecule BCL10 and MALT1 (CBM complex) represent a central hub in regulating activation of the pleiotropic transcription factor NF-κB. Recently, missense mutations in CARMA2sh have been shown to cause psoriasis in a dominant manner and with high penetrancy. Here, we demonstrate that in human keratinocytes CARMA2sh plays an essential role in the signal transduction pathway that connects pathogen-associated molecular patterns recognition to NF-κB activation...
February 23, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28230841/magnetoencephalography-for-brain-electrophysiology-and-imaging
#14
REVIEW
Sylvain Baillet
We review the aspects that uniquely characterize magnetoencephalography (MEG) among the techniques available to explore and resolve brain function and dysfunction. While emphasizing its specific strengths in terms of millisecond source imaging, we also identify and discuss current practical challenges, in particular in signal extraction and interpretation. We also take issue with some perceived disadvantages of MEG, including the misconception that the technique is redundant with electroencephalography. Overall, MEG contributes uniquely to our deeper comprehension of both regional and large-scale brain dynamics: from the functions of neural oscillations and the nature of event-related brain activation, to the mechanisms of functional connectivity between regions and the emergence of modes of network communication in brain systems...
February 23, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28230815/conceptual-foundations-of-systems-biology-explaining-complex-cardiac-diseases
#15
REVIEW
George E Louridas, Katerina G Lourida
Systems biology is an important concept that connects molecular biology and genomics with computing science, mathematics and engineering. An endeavor is made in this paper to associate basic conceptual ideas of systems biology with clinical medicine. Complex cardiac diseases are clinical phenotypes generated by integration of genetic, molecular and environmental factors. Basic concepts of systems biology like network construction, modular thinking, biological constraints (downward biological direction) and emergence (upward biological direction) could be applied to clinical medicine...
February 21, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28230727/analyzing-the-effects-of-uav-mobility-patterns-on-data-collection-in-wireless-sensor-networks
#16
Sarmad Rashed, Mujdat Soyturk
Sensor nodes in a Wireless Sensor Network (WSN) can be dispersed over a remote sensing area (e.g., the regions that are hardly accessed by human beings). In such kinds of networks, datacollectionbecomesoneofthemajorissues. Getting connected to each sensor node and retrieving the information in time introduces new challenges. Mobile sink usage-especially Unmanned Aerial Vehicles (UAVs)-is the most convenient approach to covering the area and accessing each sensor node in such a large-scale WSN. However, the operation of the UAV depends on some parameters, such as endurance time, altitude, speed, radio type in use, and the path...
February 20, 2017: Sensors
https://www.readbyqxmd.com/read/28230647/co-occurrence-of-rhabdomyosarcoma-and-mowat-wilson-syndrome-is-there-a-connection
#17
Mihael Rogac, Lidija Kitanovski, Karin Writzl
No abstract text is available yet for this article.
February 22, 2017: Clinical Dysmorphology
https://www.readbyqxmd.com/read/28230527/phloem-unloading-in-arabidopsis-roots-is-convective-and-regulated-by-the-phloem-pole-pericycle
#18
Timothy J Ross-Elliott, Kaare H Jensen, Katrine S Haaning, Brittney Michaelle Wager, Jan Knoblauch, Alexander H Howell, Daniel L Mullendore, Alexander G Monteith, Danae Paultre, Dawei Yan, Sofia Otero-Perez, Matthieu Bourdon, Ross Sager, Jung-Youn Lee, Ykä Helariutta, Michael Knoblauch, Karl John Oparka
In plants, a complex mixture of solutes and macromolecules is transported by the phloem. Here we examined how solutes and macromolecules are separated when they exit the phloem during the unloading process. We used a combination of approaches (non-invasive imaging, 3D-electron microscopy, and mathematical modelling) to show that phloem unloading of solutes in Arabidopsis roots occurs through plasmodesmata by a combination of mass flow and diffusion (convective phloem unloading). During unloading, solutes and proteins are diverted into the phloem-pole pericycle, a tissue connected to the protophloem by a unique class of 'funnel plasmodesmata'...
February 23, 2017: ELife
https://www.readbyqxmd.com/read/28230519/classification-diagnosis-and-pathogenesis-of-rare-heritable-connective-tissue-disorders-the-impact-of-differential-ultrastructural-aberrations-of-dermal-connective-tissue-components
#19
https://www.readbyqxmd.com/read/28230411/the-bilingual-adaptation-how-minds-accommodate-experience
#20
Ellen Bialystok
According to some estimates, more than half of the world's population is multilingual to some extent. Because of the centrality of language use to human experience and the deep connections between linguistic and nonlinguistic processing, it would not be surprising to find that there are interactions between bilingualism and cognitive and brain processes. The present review uses the framework of experience-dependent plasticity to evaluate the evidence for systematic modifications of brain and cognitive systems that can be attributed to bilingualism...
March 2017: Psychological Bulletin
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