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gastrointestinal manifestations of pneumonia

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https://www.readbyqxmd.com/read/27920654/a-rare-cause-of-pulmonary-nodules
#1
Michael Tsuyoshi Chew, Eric Chak, Karen Matsukuma
Crohn's disease is a chronic, idiopathic autoimmune disorder that primarily targets the gastrointestinal (GI) system. It is characterized by transmural inflammation of the GI tract that can occur anywhere from the mouth to the anus. Not infrequently, the disease may also have extraintestinal manifestations (EIMs) that can affect almost any organ system. It is estimated that EIMs affect up to 36% of patients with Crohn's disease, but the incidence and prevalence of pulmonary involvement are variable in the literature and may be as low as 0...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27714898/review-of-cytomegalovirus-coinfection-in-hiv-infected-individuals-in-africa
#2
REVIEW
Helene Ladefoged Grønborg, Sanne Jespersen, Bo Langhoff Hønge, Søren Jensen-Fangel, Christian Wejse
BACKGROUND: Cytomegalovirus (CMV) infection among HIV-infected individuals may cause end-organ disease, which is an AIDS-defining condition. Evidence from high-income countries suggests that CMV may alter the outcome of HIV infection, other than causing end-organ diseases. We reviewed literature on HIV and CMV coinfection in Africa. METHODS: Systematic review of published studies on HIV and CMV coinfection in Africa using the PubMed database. RESULTS: High CMV seroprevalence was found throughout Africa, exceeding 90% in most populations...
October 7, 2016: Reviews in Medical Virology
https://www.readbyqxmd.com/read/27560919/-use-of-intravenous-immunoglobulin-in-pregnancy-report-of-a-patient-with-common-variable-immunodeficiency
#3
Julio César Cambray-Gutiérrez, Ulises Noel García-Ramírez, Leonel Gerardo Del Rivero-Hernández, Patricia López-Pérez, Aurora Chávez-García
BACKGROUND: Common variable immunodeficiency is the most commonly-diagnosed primary immunodeficiency in adults; it is characterized by recurrent sinopulmonary and gastrointestinal infections, and increased incidence of malignancy and autoimmune processes. Many patients begin to have clinical manifestations during reproductive age. CASE REPORT: A 34-year-old woman with 12 weeks of gestation who was diagnosed with common variable immunodeficiency after recurrent episodes of rhinosinusitis, pharyngoamygdalitis, and pneumonia...
July 2016: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/27536698/ricin-toxicity-clinical-and-molecular-aspects
#4
Mohammad Moshiri, Fatemeh Hamid, Leila Etemad
Seeds of the castor bean plant Ricinuscommunis L (CB) contain ricin toxin (RT), one of the most poisonous naturally-occurring substances known. Ricin toxin, a water-soluble glycoprotein that does not partition into the oil extract, is a ribosome-inactivating toxin composed of two chains, labeled A and B. Severity of the toxicity varies depending on the route of exposure to the toxin. Inhalational is the most toxic route, followed by oral ingestion. Orally-ingested RT accumulates in the liver and spleen but other cells are also affected...
April 2016: Reports of Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/27520566/vildagliptin-induced-acute-lung-injury-a-case-report
#5
Nobumasa Ohara, Masanori Kaneko, Kazuhiro Sato, Ryoko Maruyama, Tomoyasu Furukawa, Junta Tanaka, Kenzo Kaneko, Kyuzi Kamoi
BACKGROUND: Dipeptidyl peptidase-4 inhibitors are a class of oral hypoglycemic drugs and are used widely to treat type 2 diabetes mellitus in many countries. Adverse effects include nasopharyngitis, headache, elevated serum pancreatic enzymes, and gastrointestinal symptoms. In addition, a few cases of interstitial pneumonia associated with their use have been reported in the Japanese literature. Here we describe a patient who developed drug-induced acute lung injury shortly after the administration of the dipeptidyl peptidase-4 inhibitor vildagliptin...
August 12, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27486739/adenovirus-epidemiology-global-spread-of-novel-serotypes-and-advances-in-treatment-and-prevention
#6
Joseph P Lynch, Adriana E Kajon
Adenoviruses (AdVs) are DNA viruses that typically cause mild infections involving the upper or lower respiratory tract, gastrointestinal tract, or conjunctiva. Rare manifestations of AdV infections include hemorrhagic cystitis, hepatitis, hemorrhagic colitis, pancreatitis, nephritis, or meningoencephalitis. AdV infections are more common in young children, due to lack of humoral immunity. Epidemics of AdV infection may occur in healthy children or adults in closed or crowded settings (particularly military recruits)...
August 2016: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27462187/pulmonary-crohn-s-disease-in-down-syndrome-a-link-or-linkage-problem
#7
Danyal Thaver, Mirza Beg
Crohn's disease (CD) is an autoimmune inflammatory disorder that primarily affects the gastrointestinal tract. It may have pulmonary involvement, which has been rarely reported in pediatric patients. Down syndrome (DS) has been associated with increased frequency of autoimmune diseases. However, associations between CD and DS have been rarely reported. We present the case of a 5-year-old girl with known DS and a history of chronic intermittent abdominal pain who presented with persistent pneumonia. Her workup included a chest computed tomography (CT) scan that showed multiple noncalcified pulmonary nodules...
May 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27276370/common-variable-immunodeficiency-immune-thrombocytopenia-rituximab-and-splenectomy-important-considerations
#8
Ruta Arays, Sahil Goyal, Kim M Jordan
Common variable immunodeficiency (CVID) is readily considered in patients presenting with recurrent sino-pulmonary infections, however this disease has a broad range of clinical manifestations and diagnosis can be delayed by several years. We present the case of a 44-year-old postpartum female who presented with nausea, vomiting and abdominal distension. Four years prior, she was hospitalized for treatment of immune thrombocytopenia (ITP) with splenectomy and rituximab followed by two episodes of bacterial meningitis despite immunizations...
August 2016: Postgraduate Medicine
https://www.readbyqxmd.com/read/27189378/hyper-igm-syndrome-a-report-from-the-usidnet-registry
#9
Emily A Leven, Patrick Maffucci, Hans D Ochs, Paul R Scholl, Rebecca H Buckley, Ramsay L Fuleihan, Raif S Geha, Coleen K Cunningham, Francisco A Bonilla, Mary Ellen Conley, Ronald M Ferdman, Vivian Hernandez-Trujillo, Jennifer M Puck, Kathleen Sullivan, Elizabeth A Secord, Manish Ramesh, Charlotte Cunningham-Rundles
PURPOSE: The United States Immunodeficiency Network (USIDNET) patient registry was used to characterize the presentation, genetics, phenotypes, and treatment of patients with Hyper IgM Syndrome (HIGM). METHODS: The USIDNET Registry was queried for HIGM patient data collected from October 1992 to July 2015. Data fields included demographics, criteria for diagnosis, pedigree analysis, mutations, clinical features, treatment and transplant records, laboratory findings, and mortality...
July 2016: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/27149483/molecular-epidemiology-and-clinical-manifestations-of-adenovirus-respiratory-infections-in-taiwanese-children
#10
Ya-Fang Wang, Fan-Ching Shen, Shan-Li Wang, Pin-Hwa Kuo, Huey-Pin Tsai, Ching-Chuan Liu, Jen-Ren Wang, Chia-Yu Chi
Human adenoviruses (HAdVs) are important causes of respiratory infections in children. They usually cause mild upper respiratory symptoms, but they can also produce severe pneumonia and other complications. The aims of this retrospective study were to better define the molecular epidemiology of respiratory adenoviruses circulating in Taiwanese children during 2002 and 2013, detect reinfections and co-infections, and characterize the clinical features and laboratory findings according to the causative genotypes...
May 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27134898/multiple-small-intestine-perforations-after-organophosphorous-poisoning-a-case-report
#11
Rubina Khullar Mahajan, Sudha Jasmine Rajan, John Victor Peter, Mayur Keshav Suryawanshi
Organophosphate poisoning has significant gastrointestinal manifestations including vomiting, diarrhea, cramps and increased salivation. We report an uncommon gastrointestinal complication of multiple small intestinal perforations following organophosphorus poisoning. A 28-year old male presented after ingesting dichlorvos mixed with alcohol. Following the initial cholinergic symptoms, the patient developed severe shock with fever, attributed to aspiration pneumonia. Despite appropriate antibiotics, shock was persistent...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27103560/idiopathic-pancreatitis-in-a-patient-with-a-stat3-mutation
#12
Chelsea Michaud, Brian Peppers, John Frith, Haig Tcheurekdjian, Robert Hostoffer
BACKGROUND: Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency characterized by recurrent skin infections with abscesses, recurrent pneumonias with pneumatoceles, and immunoglobulin E levels of >10 times the upper limit of normal. CASE: The patient described herein had a classic case of signal transducer and activator of transcription 3 (STAT3) deficiency associated with HIES diagnosed several years before this particular presentation. He demonstrated extraimmune manifestations of the disease as well, including characteristic facies and a history of skeletal fractures...
January 2016: Allergy & Rhinology
https://www.readbyqxmd.com/read/27076713/a-rare-aspect-of-crohn-s-disease-pulmonary-involvement-in-a-child
#13
Ebru Atike Ongun, Reha Artan, Aysen Bingol, Oguz Dursun
Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel disease activity; pulmonary involvement may be exarbecated...
February 2016: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27050889/clinical-characteristics-of-legionella-pneumonia-diagnosed-with-legionella-urinary-antigen-test
#14
Akihiro Ueda, Masayuki Oki, Hidetaka Yanagi, Hideki Ozawa, Atsushi Takagi
OBJECTIVE: The aim of our study was to describe the clinical characteristics of Legionella pneumonia diagnosed with a positive urinary antigen test, and factors associated with severe Legionella pneumonia were investigated. METHODS: We retrospectively investigated the clinical characteristics of patients with Legionella pneumonia diagnosed at Tokai University Hospital between February 2006 and June 2012. The clinical characteristics of ICU cases and non-ICU cases were compared...
April 2016: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/26963455/cardiopulmonary-and-gastrointestinal-manifestations-of-eosinophil-associated-diseases-and-idiopathic-hypereosinophilic-syndromes-multimodality-imaging-approach
#15
Rashmi S Katre, Abhijit Sunnapwar, Carlos S Restrepo, Venkata S Katabathina, Amy Mumbower, Ameya Baxi, Sushilkumar Sonavane
Eosinophil-associated diseases (EADs) are a diverse group of disorders characterized by an increase in circulating or tissue eosinophils. Cardiopulmonary and gastrointestinal system involvement can be due to primary EAD with no known cause or can be secondary to known systemic disease. The cardiopulmonary spectrum of EADs comprises simple pulmonary eosinophilia, acute eosinophilic pneumonia, chronic eosinophilic pneumonia, Churg-Strauss syndrome, allergic bronchopulmonary aspergillosis, bronchocentric granulomatosis, parasitic infections, and idiopathic hypereosinophilic syndrome...
March 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/26939756/a-case-report-of-inhalation-anthrax-acquired-naturally
#16
Zohreh Azarkar, Majid Zare Bidaki
BACKGROUND: Anthrax is a zoonotic occupational disease caused by Bacillus anthracis, a rod-shaped immobile aerobic gram-positive bacteria with spore. Anthrax occurs in humans randomly and with low frequency. Most cases of anthrax are acquired through contact with infected animals or contaminated animal products. This old disease became particularly important since 2001 that the biological spores were exploited in America. Depending on the transmission method of the disease, clinical manifestations occur in three classes: Cutaneous, respiratory, and gastrointestinal anthrax...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/26862316/mycoplasma-pneumoniae-as-a-trigger-for-henoch-sch%C3%A3-nlein-purpura-in-children
#17
Elżbieta Kuźma-Mroczkowska, Małgorzata Pańczyk-Tomaszewska, Agnieszka Szmigielska, Hanna Szymanik-Grzelak, Maria Roszkowska-Blaim
Mycoplasma pneumoniae is one of the most common causes of respiratory tract infections in children. Extrapulmonary manifestations are seen in up to 25% of infected patients. Extrapulmonary complications are associated with the central nervous system, gastrointestinal tract, skin changes, myocarditis, pericarditis, hemolytic anemia, thrombocytopenia and thrombosis. The majority of extrapulmonary symptoms are associated with skin changes such as exanthematous skin eruptions, erythema nodosum, urticaria, Stevens-Jonson syndrome...
2015: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/26855894/prevention-of-stress-related-ulcer-bleeding-at-the-intensive-care-unit-risks-and-benefits-of-stress-ulcer-prophylaxis
#18
REVIEW
Lukas Buendgens, Alexander Koch, Frank Tacke
Stress-related mucosal disease is a typical complication of critically ill patients in the intensive care unit (ICU). It poses a risk of clinically relevant upper gastrointestinal (GI) bleeding. Therefore, stress ulcer prophylaxis (SUP) is recommended in high-risk patients, especially those mechanically ventilated > 48 h and those with a manifest coagulopathy. Proton pump inhibitors (PPI) and, less effectively, histamine 2 receptor antagonists (H2RA) prevent GI bleeding in critically ill patients in the ICU...
February 4, 2016: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/26453338/the-clinical-features-of-myositis-associated-autoantibodies-a-review
#19
Harsha Gunawardena
The idiopathic inflammatory myopathies (IIM) are a group of autoimmune diseases traditionally defined by clinical manifestations including skeletal muscle weakness, skin rashes, elevated skeletal muscle enzymes, and neurophysiological and/or histological evidence of muscle inflammation. Patients with myositis overlap can develop other features including parenchymal lung disease, inflammatory arthritis, gastrointestinal manifestations and marked constitutional symptoms. Although patients may be diagnosed as having polymyositis (PM) or dermatomyositis (DM) under the IIM spectrum, it is quite clear that disease course between subgroups of patients is different...
October 9, 2015: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/26213549/hepatitis-associated-with-mycoplasma-pneumoniae-infection-in-korean-children-a-prospective-study
#20
Kyu Won Kim, Jae Jin Sung, Hann Tchah, Eell Ryoo, Hye Kyung Cho, Yong Han Sun, Kang Ho Cho, Dong Woo Son, In Sang Jeon, Yun Mi Kim
PURPOSE: Mycoplasma pneumoniae (MP) infection is a major cause of respiratory infection in school-aged children. Extrapulmonary manifestations of MP infection are common, but liver involvement has been rarely reported. The aim of this study was to determine the clinical characteristics of MP-associated hepatitis. METHODS: This prospective study included 1,044 pediatric patients with MP infection diagnosed serologically with MP IgM at one medical center from January 2006 to December 2012...
June 2015: Korean Journal of Pediatrics
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