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Keywords gastrointestinal manifestation...

gastrointestinal manifestations of pneumonia

https://read.qxmd.com/read/38535207/a-novel-carmil2-immunodeficiency-identified-in-a-subset-of-cavalier-king-charles-spaniels-with-pneumocystis-and-bordetella-pneumonia
#1
JOURNAL ARTICLE
Emily L Coffey, Liang Ma, Ousmane H Cissé, Joseph A Kovacs, Katie M Minor, Antti Sukura, Patrizia Danesi, Steven G Friedenberg, Jonah N Cullen, Christiane Weissenbacher-Lang, Julie C Nadeau, Amber M Graham, Martin N Granick, Natalie K Branson, Kyle C Branson, Barbara Blasi, Casandra M Jacobs, Eva Furrow
Pet dogs are a valuable natural animal model for studying relationships between primary immunodeficiencies and susceptibility to Pneumocystis and other opportunistic respiratory pathogens. Certain breeds, such as the Cavalier King Charles Spaniel, are over-represented for Pneumocystis pneumonia (PCP), suggesting the presence of a primary immunodeficiency in the breed. Here, we report the discovery of a CARMIL2 nonsense variant in three Cavalier King Charles Spaniel dogs with either PCP (n = 2) or refractory Bordetella pneumonia (n = 1)...
March 5, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38257854/gastrointestinal-and-hepatological-manifestations-in-severe-acute-respiratory-syndrome-coronavirus-2-infection-results-from-the-major-covid-hospital-in-serbia
#2
JOURNAL ARTICLE
Dragana Mijac, Samir Vucelj, Kristina Todorovic, Marko Vojnovic, Biljana Milicic, Snezana Lukic, Branka Filipovic, Marija Marjanovic Haljilji, Dusan Popovic, Tatjana Adzic Vukicevic
The coronavirus disease of 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), includes a clinical spectrum of diseases from mild to severe progressive pneumonia, which has affected and still affects the human population worldwide. Most commonly, it is presented by respiratory symptoms, but studies have shown that about 50% of patients with SARS-CoV-2 infection have at least one gastrointestinal symptom (GI), predominantly nausea, diarrhea, vomiting, or loss of appetite...
December 22, 2023: Microorganisms
https://read.qxmd.com/read/38256298/a-case-of-mycoplasma-infection-with-an-atypical-presentation-of-abducens-nerve-palsy-erythema-multiforme-and-polyarthritis-without-respiratory-manifestations
#3
Kiyomi Yoshimoto, Masaki Matsubara, Tadanao Kobayashi, Kenji Nishio
Mycoplasma pneumoniae is a self-propagating microorganism that commonly causes respiratory tract infections. It can also cause a variety of extrapulmonary symptoms with or independently of respiratory symptoms, such as skin lesions, arthralgia, myalgia, hemolysis, cardiac lesions, gastrointestinal symptoms, and central nervous system lesions, which are rare manifestations reported in approximately 0.1% of cases. In this study, we present a unique case of Mycoplasma-related abducens nerve palsy, polyarthritis, and erythema multiforme without respiratory disease...
December 25, 2023: Medicina
https://read.qxmd.com/read/38254176/spontaneous-splenic-rupture-associated-with-scrub-typhus-a-case-report
#4
JOURNAL ARTICLE
Hong Pil Hwang, Kyoung Min Kim, Hyojin Han, Jeong-Hwan Hwang
BACKGROUND: Scrub typhus, an acute febrile disease with mild to severe, life-threatening manifestations, potentially presents with a variety of complications, including pneumonia, acute respiratory distress syndrome, cardiac arrhythmias (such as atrial fibrillation), myocarditis, shock, peptic ulcer, gastrointestinal bleeding, meningitis, encephalitis, and renal failure. Of the various complications associated with scrub typhus, splenic rupture has rarely been reported, and its mechanisms are unknown...
January 22, 2024: Infectious Diseases of Poverty
https://read.qxmd.com/read/38223591/what-can-traditional-plant-therapy-do-in-the-face-of-covid-19-examples-from-traditional-chinese-medicine
#5
JOURNAL ARTICLE
Dandan Song, Qian Deng, Hualiang Chen
BACKGROUND: Until June 2022, more than 540.9 million people had been diagnosed with COVID-19, and the pandemic had claimed more than six million lives worldwide. Two years after fighting the virus, we faced a more uncertain position. SARS-CoV-2 is constantly mutating and reappears regularly, particularly with Omicron variants showing high genetic variation and immune escape mechanisms. The efficacy and duration of protection of existing vaccines against new variants of SARS-CoV-2 remains uncertain...
June 2023: African Health Sciences
https://read.qxmd.com/read/38156834/efficacy-and-safety-of-ibrutinib-for-chronic-graft-versus-host-disease-a-systematic-review
#6
JOURNAL ARTICLE
Damai Santosa, Daniel Rizky, Kevin Tandarto, Ika Kartiyani, Vina Yunarvika, Desta Nur Ewika Ardini, Budi Setiawan, Eko Adhi Pangarsa, Catharina Suharti
INTRODUCTION: Allogeneic hematopoietic cell transplantation (allo-HCT) serves as a potentially curative intervention for various hematologic disorders. However, its utility can be limited by the emergence of chronic graft-versus-host disease (cGVHD). The clinical manifestations of cGVHD result from a complex immune response characterized by the involvement of both B and T cells. Ibrutinib, a pharmacological agent, acts as an inhibitor of Bruton's tyrosine kinase (BTK) pathway, which becomes activated through the B-cell receptor and regulates B-cell survival...
December 1, 2023: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/38155884/the-impact-of-covid-19-on-pulmonary-neurological-and-cardiac-outcomes-evidence-from-a-mendelian-randomization-study
#7
JOURNAL ARTICLE
Pooja U Shenoy, Hrushikesh Udupa, Jyothika Ks, Sangeetha Babu, Nikshita K, Neha Jain, Ranajit Das, Priyanka Upadhyai
BACKGROUND: Long COVID is a clinical entity characterized by persistent health problems or development of new diseases, without an alternative diagnosis, following SARS-CoV-2 infection that affects a significant proportion of individuals globally. It can manifest with a wide range of symptoms due to dysfunction of multiple organ systems including but not limited to cardiovascular, hematologic, neurological, gastrointestinal, and renal organs, revealed by observational studies. However, a causal association between the genetic predisposition to COVID-19 and many post-infective abnormalities in long COVID remain unclear...
2023: Frontiers in Public Health
https://read.qxmd.com/read/38154978/-clinical-analysis-of-11-cases-multisystem-inflammatory-syndrome-associated-with-sars-cov-2-omicron-variant-infection-in-children
#8
JOURNAL ARTICLE
H S Zhang, X T Chang, P H Wu, D Y Song, G Ge, W Ding, Z W Hu, G F Wang, Y W Jiang, L P Ye
Objective: To explore the clinical characteristics, diagnosis, treatment, and follow-up of multisystem inflammatory syndrome in children (MIS-C) related to SARS-CoV-2 Omicron variant infection. Methods: A retrospective analysis was conducted on clinical data of 11 children with MIS-C, who were admitted to the Department of Pediatrics of Peking University First Hospital from December 2022 to January 2023. Clinical characteristics, treatment, and follow-up of MIS-C were summarized in this study. Results: The 11 cases contained 7 boys and 4 girls, with an age of 4...
January 2, 2024: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/38112146/-enteral-nutrition-support-for-lysinuric-protein-intolerance-a-case-report-and-literature-review
#9
JOURNAL ARTICLE
Jiao Quan, Xiao-Feng Liu, Ke Hu, Qian Hou
OBJECTIVES: To summarize the clinical characteristics and nutrition therapy for children with lysinuric protein intolerance (LPI). METHODS: The clinical manifestations, laboratory test results and enteral nutrition treatment in a girl with LPI diagnosed in Xiangya Hospital, Central South University were retrospective analyzed. Additionally, the data of the children with LPI reported in China and overseas were reviewed. RESULTS: A case of 4-year-old girl was presented, who exhibited significant gastrointestinal symptoms, such as chronic abdominal distension, prolonged diarrhea, recurrent pneumonia, and limited growth...
December 15, 2023: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://read.qxmd.com/read/37965555/-group-b-streptococci-recto-vaginal-colonization-antimicrobial-susceptibility-pattern-and-associated-factors-among-pregnant-women-at-selected-health-facilities-of-wolaita-sodo-town-southern-ethiopia
#10
JOURNAL ARTICLE
Abera Kumalo, Biruk Gebre, Shimelis Shiferaw, Wokil Wolde, Tamirayehu Shonde
BACKGROUND: Streptococcus agalactiae or Group B Streptococcal colonization of the gastrointestinal and genital tracts of pregnant women usually remains asymptomatic, even though it is the critical determinant of infection in neonates and young infants. It causes early and late onset of invasive Group B Streptococcus (GBS) disease manifesting as septicemia, meningitis, and pneumonia. Now it is recognized as an important cause of maternal and neonatal morbidity and mortality in many parts of the world including Ethiopia, where the magnitude of the problem has been little studied...
2023: Frontiers in Microbiology
https://read.qxmd.com/read/37886359/acute-abdominal-pain-as-the-first-symptom-of-chlamydia-psittaci-pneumonia-complicated-by-acute-pancreatitis-a-case-report
#11
Changquan Fang, Yanjun Xie, Hui Mai, Limin Xu
BACKGROUND: Chlamydia psittaci infections primarily cause damage to the lungs but may also affect the cardiovascular system, gastrointestinal tract, liver, kidney, and brain, resulting in a variety of extrapulmonary complications. However, reports regarding C. psittaci infection-associated pancreatitis are rare. In this report, a patient with C. psittaci pneumonia complicated by acute pancreatitis is presented. CASE DESCRIPTION: The patient presented with acute upper abdominal pain and developed severe pyrexia and dyspnoea one day later...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37835065/lung-involvement-in-inflammatory-bowel-diseases-shared-pathways-and-unwanted-connections
#12
REVIEW
Carolina Aliai Micol Cavalli, Roberto Gabbiadini, Arianna Dal Buono, Alessandro Quadarella, Alessandro De Marco, Alessandro Repici, Cristina Bezzio, Edoardo Simonetta, Stefano Aliberti, Alessandro Armuzzi
Inflammatory bowel diseases (IBDs) are chronic, relapsing inflammatory disorders of the gastrointestinal tract, frequently associated with extraintestinal manifestations (EIMs) that can severely affect IBD patients' quality of life, sometimes even becoming life-threatening. Respiratory diseases have always been considered a rare and subsequently neglected extraintestinal manifestations of IBD. However, increasing evidence has demonstrated that respiratory involvement is frequent in IBD patients, even in the absence of respiratory symptoms...
October 9, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37784218/a-case-report-of-extra-articular-manifestation-of-rheumatoid-arthritis-rheumatoid-nodules-in-lungs
#13
Saltanat Bektyrganova, Doskhan Kozhakhmet, Alexey Kim, Abay Baigenzhin, Galymzhan Togizbayev, Ainur Doszhan, Natalya Krivoruchkо, Alexey Pak, Manana Peradze, Timur Sarsengaliyev
Rheumatoid arthritis is a systemic inflammatory disorder primarily affecting joints but not limited to the joints alone. Extra-articular manifestations involve skin, ocular, gastrointestinal, pulmonary, cardiac, renal, neurological, and hematological systems. Among them, skin manifestations (20%) are most common, presenting as nodules on the extensor surfaces of the upper and lower extremities. In rare cases these nodules can also be detected within the heart and lungs. Interestingly, rheumatoid nodules are often seen in patients on leflunomide, methotrexate, or tumor necrosis factor-alpha antagonists...
October 2, 2023: International Journal of Rheumatic Diseases
https://read.qxmd.com/read/37751017/range-of-clinical-manifestations-caused-by-invasive-meningococcal-disease-due-to-serogroup-w-a-systematic-review
#14
REVIEW
Isabelle Bertrand-Gerentes, Laurent Fanchon, Florence Coste, Richard E Glover, Tamazoust Guiddir, Muhamed-Kheir Taha
INTRODUCTION: Invasive meningococcal disease (IMD) due to serogroup W meningococci (MenW) is consistently reported with atypical clinical manifestations, including gastrointestinal symptoms, bacteremic pneumonia, and septic arthritis. We undertook a systematic review of the literature for a comprehensive assessment of the clinical presentation of IMD caused by MenW. METHODS: PubMed and Embase databases were searched from inception to June 2022 using a combination of MeSH terms and free text for articles that reported symptoms and signs of MenW IMD, and associated manifestations...
September 26, 2023: Infectious Diseases and Therapy
https://read.qxmd.com/read/37736443/herpetic-esophagitis-a-cause-of-dysphagia-in-a-malnourished-patient
#15
Bárbara Sousa, Joana Silva, Elsa Araújo, Raquel Costa, Andre Calheiros
Herpetic esophagitis (HE) is an esophageal infection caused by herpes simplex virus (HSV). Although less common, it can occasionally affect immunocompetent hosts. It can manifest as odynophagia and/or dysphagia and should lead to an investigation by upper digestive endoscopy with a biopsy. The authors report a case of a 65-year-old man with a past medical history relevant for schizophrenia, oligophrenia, and malnutrition, and no other history or evidence of immunosuppression, who presented with severe dysphagia over weeks and recent episodes of food aspiration with consequent pneumonia...
August 2023: Curēus
https://read.qxmd.com/read/37731996/carcinoid-syndrome-caused-by-a-pulmonary-carcinoid-mimics-intestinal-manifestations-of-ulcerative-colitis-a-case-report
#16
Carmen Mota Reyes, Henriette Klein, Fabian Stögbauer, Henrik Einwächter, Melanie Boxberg, Moritz Schirren, Seyer Safi, Hans Hoffmann
BACKGROUND: Pulmonary carcinoids are rare, low-grade malignant tumors characterized by neuroendocrine differentiation and relatively indolent clinical behavior. Most cases present as a slow-growing polypoidal mass in the major bronchi leading to hemoptysis and pulmonary infection due to blockage of the distal bronchi. Carcinoid syndrome is a paraneoplastic syndrome caused by the systemic release of vasoactive substances that presents in 5% of patients with neuroendocrine tumors. Due to such nonspecific presentation, most patients are misdiagnosed or diagnosed late and may receive several courses of antibiotics to treat recurrent pneumonia before the tumor is diagnosed...
September 7, 2023: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/37726566/effect-of-the-covid-19-pandemic-on-the-pediatric-infectious-disease-landscape
#17
REVIEW
Moshe Shmueli, Idan Lendner, Shalom Ben-Shimol
This narrative review aims to present an overview of the COVID-19 pandemic's effects on the landscape of pediatric infectious diseases. While COVID-19 generally results in mild symptoms and a favorable prognosis in children, the pandemic brought forth significant consequences. These included persistent symptoms among infected children ("long COVID"), a profound transformation in healthcare utilization (notably through the widespread adoption of telemedicine), and the implementation of optimization strategies within healthcare settings...
September 20, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37693950/overlapping-clinical-presentation-of-mycoplasma-induced-rash-and-mucositis-and-drug-induced-stevens-johnson-syndrome-a-case-report
#18
Elias Marquart, Tamar Kinaciyan
INTRODUCTION: Mycoplasma pneumoniae is a worldwide occurring common bacterial agent for community-acquired pneumonia especially in children and young people with high contagiousness. Extrapulmonary complications such as cardiopulmonary, gastrointestinal, neurological and mucocutaneous manifestations including Mycoplasma pneumoniae-induced rash and mucositis (MIRM) may occur especially in adults. MIRM is an important differential diagnosis of Stevens Johnson Syndrome (SJS). Both clinically present similar as mucocutaneous erosive eruptions but have different etiologies...
2023: IDCases
https://read.qxmd.com/read/37629790/the-prevalence-of-gastrointestinal-bleeding-in-covid-19-patients-a-systematic-review-and-meta-analysis
#19
REVIEW
Eleni Karlafti, Dimitrios Tsavdaris, Evangelia Kotzakioulafi, Adonis A Protopapas, Georgia Kaiafa, Smaro Netta, Christos Savopoulos, Antonios Michalopoulos, Daniel Paramythiotis
Introduction : Severe acute respiratory syndrome coronavirus 2 caused the coronavirus disease of 2019 (COVID-19), which rapidly became a pandemic, claiming millions of lives. Apart from the main manifestations of this infection concerning the respiratory tract, such as pneumonia, there are also many manifestations from the gastrointestinal tract. Of these, bleeding from the gastrointestinal tract is a significant complication quite dangerous for life. This bleeding is divided into upper and lower, and the primary pathophysiological mechanism is the entering of the virus into the host cells through the Angiotensin-converting enzyme 2 receptors...
August 21, 2023: Medicina
https://read.qxmd.com/read/37554981/characteristic-analysis-of-adverse-reactions-of-five-anti-tnf%C3%A9-agents-a-descriptive-analysis-from-who-vigiaccess
#20
JOURNAL ARTICLE
Mingming Li, Ruxu You, Yuyong Su, Hongbo Zhou, Shiwei Gong
Introduction: Tumor necrosis factor (TNF) inhibitors (adalimumab, infliximab, etanercept, golimumab, and certolizumab pegol) have revolutionized the treatment of severe immune-mediated inflammatory diseases, including rheumatoid arthritis, Crohn's disease, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This study assessed adverse drug reactions (ADRs) after the use of TNFα inhibitors in VigiAccess of the World Health Organization (WHO) and compared the adverse reaction characteristics of five inhibitors to select the drug with the least risk for individualized patient use...
2023: Frontiers in Pharmacology
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