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https://www.readbyqxmd.com/read/29221514/yield-of-brain-mri-in-clinically-diagnosed-epilepsy-in-the-kingdom-of-bhutan-a-prospective-study
#1
Veronica Bruno, Joshua P Klein, Dechen Nidup, Damber K Nirola, Lhab Tshering, Sonam Deki, Sarah J Clark, Kristin A Linn, Russell T Shinohara, Chencho Dorji, Dili Ram Pokhrel, Ugyen Dema, Farrah J Mateen
BACKGROUND: People with epilepsy (PWE) in low- and middle-income countries may not access the health resources that are considered optimal for epilepsy diagnosis. The diagnostic yield of magnetic resonance imaging (MRI) has not been well studied in these settings. OBJECTIVES: To report the diagnostic yield of brain MRI and identify clinical associations of abnormal MRI findings among PWE in a neurocysticercosis-endemic, resource-limited setting and to identify the proportion and putative structural brain causes of drug-resistant epilepsy...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29204024/behavioral-problems-and-intelligence-quotient-changes-in-pediatric-epilepsy-a-case-control-study
#2
Shyama Choudhary, N Niranjan, Satyendra Khichar, Pramod K Berwal, Abhijeet Singh Barath
Background: Epilepsy is the most common chronic neurological disease and has neurological impairment as an important comorbidity. Objective: To find behavioral problems and intelligence quotient (IQ) changes associated with epilepsy and to know the association of variables such as frequency, type of seizures, and duration of disease with cognitive impairment. Materials and Methods: A descriptive cross sectional study, consisting of 50 cases (patients of epilepsy) and 50 controls (other patients of same socioeconomic status) was conducted at S...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29198174/intracranial-complications-of-midline-nasal-dermoid-cysts
#3
Dries Opsomer, Toon Allaeys, Ann-Sofie Alderweireldt, Edward Baert, Nathalie Roche
BACKGROUND: Nasal dermoid cysts are common tumors in children. Due to anomalies in embryologic development of the nasal complex, sometimes an intracranial extension exists. When these cysts become infected they can lead to meningitis, brain abscess and death. METHODS: We report the case of a 1.5-year-old girl admitted to the paediatric intensive care unit after infection of a nasal dermoid cyst. RESULTS: The infant had a spiking fever and epileptic seizures...
December 4, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29184354/carbamazepine-induced-seizure-in-a-nonepileptic-child
#4
Rajesh Benny, Vyankatesh Bolegave, Sameer Sadavarte, Vinayak Khatav
No abstract text is available yet for this article.
October 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29179103/factors-associated-with-behavioral-problems-and-cognitive-impairment-in-children-with-epilepsy-of-kinshasa-democratic-republic-of-the-congo
#5
Thierry Matonda-Ma-Nzuzi, Samuel Mampunza Ma Miezi, Magloire Nkosi Mpembi, Diane Muanza Mvumbi, Michel Ntentani Aloni, Fanny Malendakana, Davin Mpaka Mbeya, Gilbert Mananga Lelo, Dominique Charlier-Mikolajczak
BACKGROUND: Behavioral problems and cognitive impairment are common in children with epilepsy (CWE). In sub-Saharan Africa, little is known about these comorbidities particularly their relationships with socioeconomic features. The goal of this study was to identify clinical and socioeconomic factors associated with behavioral problems and cognitive impairment in CWE of Kinshasa (Democratic Republic of the Congo). METHODS: This cross-sectional hospital-based study had included 104 CWE aged 6 to 17years...
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29175563/do-neurologists-around-the-world-agree-when-diagnosing-epilepsy-results-of-an-international-epinet-study
#6
Peter S Bergin, Ettore Beghi, Lynette G Sadleir, Manjari Tripathi, Mark P Richardson, Elisa Bianchi, Wendyl J D'Souza
OBJECTIVE: Previous studies have shown moderate agreement between physicians when diagnosing epilepsy, but have included small numbers. The EpiNet study group was established to undertake multicentre clinical trials in epilepsy. Before commencing trials, we wanted to determine levels of agreement between physicians from different countries and different health systems when diagnosing epilepsy, specific seizure types and etiologies. METHODS: 30 Case scenarios describing six children and 24 adults with paroxysmal events (21 epileptic seizures, nine non-epileptic attacks) were presented to physicians with an interest in epilepsy...
October 26, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29173305/epilepsy-or-a-seizure-disorder-parental-knowledge-and-misconceptions-about-terminology
#7
Margot Nagan, Mauro Caffarelli, Stephanie Donatelli, N Paul Rosman
OBJECTIVE: To assess primary caregiver understanding of the term epilepsy. STUDY DESIGN: A cross-sectional telephone survey evaluated understanding of the term epilepsy among primary caregivers of children diagnosed with epilepsy at an urban referral center during a 24-month period. Three measures of primary caregiver understanding were used: (1) identifying if their child had a seizure disorder, epilepsy, or both; (2) providing an open-ended definition of epilepsy; and (3) selecting from a multiple-choice definition of epilepsy...
December 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29172138/non-epileptic-seizures-in-children-views-and-approaches-at-a-uk-child-and-adolescent-psychiatry-conference
#8
Andrew McWilliams, Colin Reilly, Isobel Heyman
PURPOSE: To describe clinical experiences of paediatric non-epileptic seizures (NES) among doctors attending a UK child and adolescent psychiatry conference. METHODS: Sixty-six participants completed a semi-structured bespoke questionnaire. Results are reported using descriptive statistics. RESULTS: Two-thirds of respondents regarded the best name for the disorder to be "non-epileptic seizures". Although most doctors saw new cases each year, two-thirds described their own service as poorly equipped to manage NES...
October 31, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29170352/55%C3%A2-mini-sim-innovative-bite-sized-simulation-teaching-in-a-busy-children-s-emergency-department
#9
Rachel Sunley, Karen Moloney, Jessica Parker, Christopher Arrowsmith, Kirsty Brown, Alex Wilson
: Emergency Medicine requires a highly skilled workforce who are passionate about delivering excellent patient care. Shift patterns linked with the ever increasing numbers of patients who attend Emergency Departments puts strain on educating the workforce and fostering team togetherness.Our objective in devising and instigating the 'Mini Sim' programme was to embed regular in-situ simulation training to enhance the learning of all staff within our Emergency Department team, building a highly trained workforce to deliver excellent care within the remit of our busy department...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29167751/diffusion-tensor-imaging-in-an-infant-undergoing-functional-hemispherectomy-a-surgical-aid
#10
Allen L Ho, Arjun V Pendharkar, Eric S Sussman, May Casazza, Gerald A Grant
Hemispherectomy is a highly effective treatment option for children with severe, unilateral, medically refractory epilepsy. Many patients undergoing hemispherectomy are younger patients with dysmorphic brains, making accomplishing a complete disconnection challenging due to anatomic distortion, even with the aid of intraoperative navigation. Diffusion tensor imaging (DTI) has been proposed as a valuable imaging adjunct perioperatively to help guide surgeons intraoperatively, as well as for post-surgical evaluation and confirmation of complete hemispheric disconnection...
September 18, 2017: Curēus
https://www.readbyqxmd.com/read/29167084/parent-s-experiences-of-their-children-suffering-febrile-seizures
#11
Emma Westin, Märta Sund Levander
PURPOSE: To explore parents' experiences of their child suffering febrile seizures. DESIGN AND METHOD: Seven mothers and four fathers with experience of one or several febrile seizures in their children were interviewed. A qualitative content analysis with an inductive approach was performed. RESULT: Five themes emerged; emotional experiences, in terms of anxiety and fear, and need for control, need for support, need for acknowledgement and need for comfort...
November 11, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29157096/complementary-and-alternative-medicine-the-mozart-effect-on-childhood-epilepsy-a-systematic-review
#12
Dana E Brackney, Jessica L Brooks
This systematic review examines the effectiveness of Mozart's music in decreasing seizures in children with epilepsy (Mozart Effect) using the Johns Hopkins Nursing Evidence-Based Practice rating scale(©). A search for articles with "Mozart Effect," "child*," and "epilepsy" was conducted in CINAHL Complete, Science Direct, Cochrane, and PubMed databases. Eight studies were selected based on the exclusion and inclusion criteria after removal of duplicates ( n = 17) and others ( n = 46). Studies included were English language, peer reviewed, published between April 2010 and February 2017, and available in full text with an abstract...
January 1, 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/29156988/high-definition-transcranial-direct-current-stimulation-in-early-onset-epileptic-encephalopathy-a-case-study
#13
Oded Meiron, Rena Gale, Julia Namestnic, Odeya Bennet-Back, Jonathan David, Nigel Gebodh, Devin Adair, Zeinab Esmaeilpour, Marom Bikson
PRIMARY OBJECTIVE: Early onset epileptic encephalopathy is characterized by high daily seizure-frequency, multifocal epileptic discharges, severe psychomotor retardation, and death at infancy. Currently, there are no effective treatments to alleviate seizure frequency and high-voltage epileptic discharges in these catastrophic epilepsy cases. The current study examined the safety and feasibility of High-Definition transcranial direct current stimulation (HD-tDCS) in reducing epileptiform activity in a 30-month-old child suffering from early onset epileptic encephalopathy...
November 20, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29153996/clinical-presentation-of-anti-n-methyl-d-aspartate-receptor-and-anti-voltage-gated-potassium-channel-complex-antibodies-in-children-a-series-of-24-cases
#14
Bahadir Konuskan, Mirac Yildirim, Haluk Topaloglu, Ilknur Erol, Ulkuhan Oztoprak, Huseyin Tan, Rahsan Gocmen, Banu Anlar
OBJECTIVE: The symptomatology and paraclinical findings of antibody-mediated encephalitis, a relatively novel disorder, are still being characterized in adults and children. A high index of suspicion is needed in order to identify these cases among children presenting with various neurological symptoms. The aim of this study is to examine the clinical, demographic and laboratory findings and outcome of children with anti-NMDAR and anti-VGKC encephalitis for any typical or distinctive features...
November 7, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29138035/defining-failed-induction-of-labor
#15
William A Grobman, Jennifer Bailit, Yinglei Lai, Uma M Reddy, Ronald J Wapner, Michael W Varner, John M Thorp, Kenneth J Leveno, Steve N Caritis, Mona Prasad, Alan T N Tita, George Saade, Yoram Sorokin, Dwight J Rouse, Sean C Blackwell, Jorge E Tolosa
BACKGROUND: While there are well-accepted standards for the diagnosis of arrested active-phase labor, the definition of a "failed" induction of labor remains less certain. One approach to diagnosing a failed induction is based on the duration of the latent phase. However, a standard for the minimum duration that the latent phase of a labor induction should continue, absent acute maternal or fetal indications for cesarean delivery, remains lacking. OBJECTIVE: The objective of this study was to determine the frequency of adverse maternal and perinatal outcomes as a function of the duration of the latent phase among nulliparous women undergoing labor induction...
November 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29127615/fungal-and-parasitic-cns-infections
#16
Pratibha Singhi, Arushi Gahlot Saini
Central nervous system fungal infections can be broadly divided into those that infect a healthy host such as Cryptococcus, Coccidioides, Histoplasma, Blastomyces, Sporothrix spp., and those that cause opportunistic infections in an immunocompromised host such as Candida, Aspergillus, Zygomycetes, Trichosporon spp. The clinical manifestations of central nervous system fungal infections commonly seen in children in clinical practice include a chronic meningitis or meningoencephalitis syndrome, brain abscess, rhino-cerebral syndrome and rarely, a fungal ventriculitis...
November 11, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29126702/delay-in-pediatric-epilepsy-surgery-a-caregiver-s-perspective
#17
Alice Shen, Kara T Quaid, Brenda E Porter
The timing of epilepsy surgery is complex, and there is not a structured pathway to help families decide whether to continue medical management or pursue surgical treatment. We surveyed caregivers of pediatric epilepsy surgery patients. Fifty-eight respondents answered the majority of questions. Thirty caregivers wished their child had undergone epilepsy surgery earlier compared with twenty who felt surgery was done at the appropriate time, and eight were unsure. In retrospect, caregivers who wished their child's surgery had been performed sooner had a significantly longer duration of epilepsy prior to the surgery [44...
November 7, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29119207/anesthesia-in-a%C3%A2-child-with-suspected-peroxisomal-disorder
#18
J S Englbrecht, M Maas
We present the case of an 8‑year-old female child with suspected peroxisomal disorder requiring general anesthesia for adenotomy, paracentesis and brainstem-evoked response audiometry. Peroxisomes are small intracellular organelles that catalyse key metabolic reactions. Peroxisomal disorders are a heterogeneous group of rare genetic diseases. Anesthesia can be challenging as adrenal insufficiency, mental retardation, muscle weakness, risk of pulmonary aspiration, airway complications, seizure disorders and altered pharmacokinetics and pharmacodynamics can occur in these patients but guidelines for anesthesia do not exist due to the heterogeneity and rarity of these diseases and case reports are rare...
November 8, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29108913/development-and-content-validation-of-a-preliminary-core-set-of-patient-and-caregiver-relevant-outcomes-for-inclusion-in-a-potential-composite-endpoint-for-dravet-syndrome
#19
Rima Nabbout, Stephane Auvin, Catherine Chiron, John Irwin, Arun Mistry, Nicola Bonner, Nicola Williamson, Bryan Bennett
BACKGROUND: Dravet Syndrome (DS) is a rare developmental and epileptic encephalopathy characterized by multiple seizures, frequently prolonged and treatment refractory, with significant developmental disabilities and behavioral and psychiatric disorders. Patients with DS require intensive support and supervision from a caregiver, impacting significantly on both patients' and caregivers' lives. This study aimed to identify core concepts to measure the impact on both patients and caregivers in future DS clinical trials...
November 3, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29102350/prevalence-of-cerebral-palsy-in-uganda-a-population-based-study
#20
Angelina Kakooza-Mwesige, Carin Andrews, Stefan Peterson, Fred Wabwire Mangen, Ann Christin Eliasson, Hans Forssberg
BACKGROUND: Few population-based studies of cerebral palsy have been done in low-income and middle-income countries. We aimed to examine cerebral palsy prevalence and subtypes, functional impairments, and presumed time of injury in children in Uganda. METHODS: In this population-based study, we used a nested, three-stage, cross-sectional method (Iganga-Mayuge Health and Demographic Surveillance System [HDSS]) to screen for cerebral palsy in children aged 2-17 years in a rural eastern Uganda district...
December 2017: Lancet Global Health
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