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https://www.readbyqxmd.com/read/28100968/direct-measurement-of-left-atrial-pressure-during-routine-transradial-catheterization
#1
Faisal Fa'ak, Bahaeddin Shabaneh, George Younis
Left atrial pressure indicates the left ventricular filling pressure in patients who have systolic or diastolic left ventricular dysfunction or valvular heart disease. The use of indirect surrogate methods to determine left atrial pressure has been essential in the modern evaluation and treatment of cardiovascular disease because of the difficulty and inherent risks associated with direct methods (typically the transseptal approach). One method that has been widely used to determine left atrial pressure indirectly is Swan-Ganz catheterization, in which a balloon-flotation technique is applied to measure pulmonary capillary wedge pressure; however, this approach has been associated with several limitations and potential risks...
December 2016: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28097844/-angel-shaped-phalango-epiphyseal-dysplasia-case-report
#2
René Conci, Alicia Oller, Martín Moya, Adriana Echegaray, Donald Frush
We describe a rare and sporadic condition, characterized by swan neck deformity in hands, hip osteoarthritis in adulthood and malformations of the middle phalanges with an angel shape. The patient is a 4 year old boy who suffered hand trauma and on x-ray examination he was diagnosed with angel-shaped phalango-epiphyseal dysplasia. Based on this diagnosis, his mother, who suffered from constant pain in her hips and lower limbs, was diagnosed with this syndrome as well.
1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28096360/measurement-of-cortical-elasticity-in-drosophila-melanogaster-embryos-using-ferrofluids
#3
Konstantin Doubrovinski, Michael Swan, Oleg Polyakov, Eric F Wieschaus
Many models of morphogenesis are forced to assume specific mechanical properties of cells, because the actual mechanical properties of living tissues are largely unknown. Here, we measure the rheology of epithelial cells in the cellularizing Drosophila embryo by injecting magnetic particles and studying their response to external actuation. We establish that, on timescales relevant to epithelial morphogenesis, the cytoplasm is predominantly viscous, whereas the cellular cortex is elastic. The timescale of elastic stress relaxation has a lower bound of 4 min, which is comparable to the time required for internalization of the ventral furrow during gastrulation...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28094608/surveillance-for-avian-influenza-virus-in-wild-birds-in-poland-2008-2015
#4
Edyta Świętoń, Krzysztof Wyrostek, Michał Jóźwiak, Monika Olszewska-Tomczyk, Katarzyna Domańska-Blicharz, Włodzimierz Meissner, Radosław Włodarczyk, Piotr Minias, Tomasz Janiszewski, Zenon Minta, Krzysztof Śmietanka
We tested wild birds in Poland during 2008-2015 for avian influenza virus (AIV). We took 10,312 swabs and feces samples from 6,314 live birds representing 12 orders and 84 bird species, mostly from orders Anseriformes and Charadriiformes, for testing and characterization by various PCR methods. From PCR-positive samples, we attempted to isolate and subtype the virus. The RNA of AIV was detected in 1.8% (95% confidence interval, 1.5%-2.1%) of birds represented by 48 Mallards ( Anas platyrhynchos ), 11 Mute Swans ( Cygnus olor ), 48 Common Teal ( Anas crecca ), three Black-headed Gulls (Chroicocephalus ridibundus), one Common Coot ( Fulica atra ), one Garganey (Spatula querquedula), and one unidentified bird species...
January 17, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28092958/moments-of-von-mises-and-fisher-distributions-and-applications
#5
Thomas Hillen, Kevin J Painter, Amanda C Swan, Albert D Murtha
The von Mises and Fisher distributions are spherical analogues to the Normal distribution on the unit circle and unit sphere, respectively. The computation of their moments, and in particular the second moment, usually involves solving tedious trigonometric integrals. Here we present a new method to compute the moments of spherical distributions, based on the divergence theorem. This method allows a clear derivation of the second moments and can be easily generalized to higher dimensions. In particular we note that, to our knowledge, the variance-covariance matrix of the three dimensional Fisher distribution has not previously been explicitly computed...
June 1, 2017: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/28090298/in-situ-expression-of-bcl-2-in-pulmonary-artery-endothelial-cells-associates-with-pulmonary-arterial-hypertension-relative-to-heart-failure-with-preserved-ejection-fraction
#6
Raymond L Benza, Gretchen Williams, Changgong Wu, Kelly J Shields, Amresh Raina, Srinivas Murali, Michael J Passineau
We have previously reported that pulmonary artery endothelial cells (PAECs) can be harvested from the tips of discarded Swan-Ganz catheters after right heart catheterization (RHC). In this study, we tested the hypothesis that the existence of an antiapoptotic phenotype in PAECs obtained during RHC is a distinctive feature of pulmonary arterial hypertension (PAH; World Health Organization group 1) and might be used to differentiate PAH from other etiologies of pulmonary hypertension. Specifically, we developed a flow cytometry-based measure of Bcl-2 activity, referred to as the normalized endothelial Bcl-2 index (NEBI)...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28074227/heavy-metals-in-liver-and-brain-of-waterfowl-from-the-evros-delta-greece
#7
Maria Aloupi, Asimina Karagianni, Savas Kazantzidis, Triantaphyllos Akriotis
The concentrations of six heavy metals (cadmium [Cd], chromium [Cr], copper [Cu], manganese [Mn], lead [Pb], and zinc [Zn]) were determined in liver and brain of nine species of waterfowl from the Evros Delta, one of the most important wetlands in Greece, to assess metal contamination and potential risk to waterfowl. Significant differences among species were found for hepatic Cr, Cu, Pb, and Zn; the highest levels of all metals were found in liver of mute swans. Cd increased significantly with age in both organs of wigeon; some differences were also observed between males and females of the same species...
January 10, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28071838/electron-solvation-and-the-unique-liquid-structure-of-a-mixed-amine-expanded-metal-the-saturated-li-nh3-menh2-system
#8
Andrew G Seel, Helen Swan, Daniel T Bowron, Jonathan C Wasse, Thomas Weller, Peter P Edwards, Christopher A Howard, Neal T Skipper
Metal-amine solutions provide a unique arena in which to study electrons in solution, and to tune the electron density from the extremes of electrolytic through to true metallic behavior. The existence and structure of a new class of concentrated metal-amine liquid, Li-NH3 -MeNH2 , is presented in which the mixed solvent produces a novel type of electron solvation and delocalization that is fundamentally different from either of the constituent systems. NMR, ESR, and neutron diffraction allow the environment of the solvated electron and liquid structure to be precisely interrogated...
January 10, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28062701/widespread-virus-replication-in-alveoli-drives-acute-respiratory-distress-syndrome-in-aerosolized-h5n1-influenza-infection-of-macaques
#9
Elizabeth R Wonderlich, Zachary D Swan, Stephanie J Bissel, Amy L Hartman, Jonathan P Carney, Katherine J O'Malley, Adebimpe O Obadan, Jefferson Santos, Reagan Walker, Timothy J Sturgeon, Lonnie J Frye, Pauline Maiello, Charles A Scanga, Jennifer D Bowling, Anthea L Bouwer, Parichat A Duangkhae, Clayton A Wiley, JoAnne L Flynn, Jieru Wang, Kelly S Cole, Daniel R Perez, Douglas S Reed, Simon M Barratt-Boyes
Human infections with highly pathogenic avian influenza A (H5N1) virus are frequently fatal but the mechanisms of disease remain ill-defined. H5N1 infection is associated with intense production of proinflammatory cytokines, but whether this cytokine storm is the main cause of fatality or is a consequence of extensive virus replication that itself drives disease remains controversial. Conventional intratracheal inoculation of a liquid suspension of H5N1 influenza virus in nonhuman primates likely results in efficient clearance of virus within the upper respiratory tract and rarely produces severe disease...
January 6, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28060391/intravitreal-versus-subretinal-tissue-plasminogen-activator-injection-for-submacular-hemorrhage
#10
James E Bell, Julia P Shulman, Russell J Swan, Michael P Teske, Paul S Bernstein
BACKGROUND AND OBJECTIVE: The objective of this study was to compare visual acuity outcomes between the following procedures used to treat submacular hemorrhages: pneumatic displacement followed by intravitreal tissue plasminogen activator (tPA) if needed (pneumatic ± tPA) and pars plana vitrectomy (PPV) with subretinal tPA (PPV + tPA). PATIENTS AND METHODS: This is a retrospective chart review of submacular hemorrhages treated with either pneumatic ± tPA or PPV + tPA...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28053151/optimized-temporal-pattern-of-brain-stimulation-designed-by-computational-evolution
#11
David T Brocker, Brandon D Swan, Rosa Q So, Dennis A Turner, Robert E Gross, Warren M Grill
Brain stimulation is a promising therapy for several neurological disorders, including Parkinson's disease. Stimulation parameters are selected empirically and are limited to the frequency and intensity of stimulation. We varied the temporal pattern of deep brain stimulation to ameliorate symptoms in a parkinsonian animal model and in humans with Parkinson's disease. We used model-based computational evolution to optimize the stimulation pattern. The optimized pattern produced symptom relief comparable to that from standard high-frequency stimulation (a constant rate of 130 or 185 Hz) and outperformed frequency-matched standard stimulation in a parkinsonian rat model and in patients...
January 4, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28051805/%C3%A2-metastatic-lymphoepithelioma-like-hepatocellular-carcinoma-a-potential-diagnostic-pitfall-and-demonstration-of-pd-l1-expression
#12
Juan Putra, Todd A Anderson, Sasan Roayaie, Miho Maeda, Swan N Thung
No abstract text is available yet for this article.
January 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28050808/development-and-implementation-of-a-mental-health-finder-software-tool-within-an-electronic-medical-record-system
#13
D Swan, A Hannigan, S Higgins, R McDonnell, D Meagher, W Cullen
BACKGROUND: In Ireland, as in many other healthcare systems, mental health service provision is being reconfigured with a move toward more care in the community, and particularly primary care. Recording and surveillance systems for mental health information and activities in primary care are needed for service planning and quality improvement. AIMS: We describe the development and initial implementation of a software tool ('mental health finder') within a widely used primary care electronic medical record system (EMR) in Ireland to enable large-scale data collection on the epidemiology and management of mental health and substance use problems among patients attending general practice...
January 3, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28047262/tu-h-campus-iep3-03-validation-of-image-registration-methods-for-brain-magnetic-resonance-imaging
#14
J Lin, D Fuentes, A Chandler, J Hazle, D Schellingerhout, C MacLellan
PURPOSE: To assess the performance of both commercial and open-source co-registration solutions as applied to intra-subject, multi-sequence, magnetic resonance (MR) images of the brain. METHODS: Twenty (20) patients were imaged on clinical 3.0T MR scanners to obtain T2-weighted (T2W), fluid attenuation inversion recovery (FLAIR), susceptibility weighted angiography (SWAN), and T1 post-contrast (T1C) image sequences. Fiducial landmark sites (n=15 per sequence, 4 sequences per patient, 1200 total planned for 4 sequences and 20 patients, 1175 total realized) were specified throughout these image volumes to define identical locations across sequences...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043193/adhd-traits-in-german-school-aged-children
#15
Yoanna Schulz-Zhecheva, Manuel Voelkle, André Beauducel, Nadja Buch, Christian Fleischhaker, Stephan Bender, Christopher W N Saville, Monica Biscaldi, Christoph Klein
OBJECTIVE: The Strengths and Weaknesses of ADHS-Symptoms and Normal Behavior (SWAN) Scale has been developed to support the dimensional assessment of ADHD symptoms by capturing variance on both poles of the ADHD continuum. The present study provides the first validation of the German version of SWAN (SWAN-DE). METHOD: Based on a sample of N1 = 343 children from the general population and N2 = 62 children with ADHD, both aged between 8 and 18 years, normality, internal consistency, test-retest reliability, and different validity indices were examined...
January 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28039909/global-synthesis-of-the-temperature-sensitivity-of-leaf-litter-breakdown-in-streams-and-rivers
#16
J J Follstad Shah, J S Kominoski, M Ardón, W K Dodds, M O Gessner, N A Griffiths, C P Hawkins, S L Johnson, A Lecerf, C J LeRoy, D W P Manning, A D Rosemond, R L Sinsabaugh, C M Swan, J R Webster, L H Zeglin
Streams and rivers are important conduits of terrestrially derived carbon (C) to atmospheric and marine reservoirs. Leaf litter breakdown rates are expected to increase as water temperatures rise in response to climate change. The magnitude of increase in breakdown rates is uncertain, given differences in litter quality and microbial and detritivore community responses to temperature, factors that can influence the apparent temperature sensitivity of breakdown and the relative proportion of C lost to the atmosphere vs...
December 31, 2016: Global Change Biology
https://www.readbyqxmd.com/read/28032648/the-use-of-simulation-to-reduce-the-domain-of-black-swans-with-application-to-hurricane-impacts-to-power-systems
#17
Christine L Berner, Andrea Staid, Roger Flage, Seth D Guikema
Recently, the concept of black swans has gained increased attention in the fields of risk assessment and risk management. Different types of black swans have been suggested, distinguishing between unknown unknowns (nothing in the past can convincingly point to its occurrence), unknown knowns (known to some, but not to relevant analysts), or known knowns where the probability of occurrence is judged as negligible. Traditional risk assessments have been questioned, as their standard probabilistic methods may not be capable of predicting or even identifying these rare and extreme events, thus creating a source of possible black swans...
December 29, 2016: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28028593/quantification-of-dimethylsulfoniopropionate-dmsp-in-acropora-spp-of-reef-building-coral-using-mass-spectrometry-with-deuterated-internal-standard
#18
Hilton B Swan, Elisabeth S M Deschaseaux, Graham B Jones, Bradley D Eyre
Dimethylsulfoniopropionate (DMSP) in scleractinian coral is usually analysed indirectly as dimethylsulfide (DMS) using gas chromatography (GC) with a sulfur-specific detector. We developed a headspace GC method for mass spectral analysis of DMSP in branching coral where hexa-deuterated DMSP (d 6 -DMSP) was added to samples and standards to optimise the analytical precision and quantitative accuracy. Using this indirect HS-GC-MS method, we show that common coral sample handling techniques did not alter DMSP concentrations in Acropora aspera and that endogenous DMS was insignificant compared to the store of DMSP in A...
December 27, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28024552/the-swan-ganz-catheter-remains-a-critically-important-component-of-monitoring-in-cardiovascular-critical-care
#19
Matthew Lee, Gerard F Curley, Mary Mustard, C David Mazer
Few inventions in modern medicine have generated as passionate and extended debate as the pulmonary artery catheter (PAC). Since its introduction in 1970, the PAC remains an indispensable monitor in cardiovascular critical care. Despite attempts to develop less invasive alternatives, the PAC remains unequaled as a single monitoring device capable of measuring physiological derangement in most components of the circulation, in the awake or sedated patient, with real-time feedback on the efficacy of an intervention...
January 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28005303/radiographic-appearance-of-presumed-noncardiogenic-pulmonary-edema-and-correlation-with-the-underlying-cause-in-dogs-and-cats
#20
Sarah Bouyssou, Swan Specchi, Loïc Desquilbet, Pascaline Pey
Noncardiogenic pulmonary edema is an important cause of respiratory disease in dogs and cats but few reports describe its radiographic appearance. The purpose of this retrospective case series study was to describe radiographic findings in a large cohort of dogs and cats with presumed noncardiogenic pulmonary edema and to test associations among radiographic findings versus cause of edema. Medical records were retrieved for dogs and cats with presumed noncardiogenic edema based on history, radiographic findings, and outcome...
December 22, 2016: Veterinary Radiology & Ultrasound
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