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Right ventricular outflow tract

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https://www.readbyqxmd.com/read/29779123/pulmonary-valve-replacement-after-repaired-tetralogy-of-fallot
#1
REVIEW
Hideki Tatewaki, Akira Shiose
In this review article, we describe pulmonary valve replacement (PVR) late after repaired Tetralogy of Fallot (TOF). Since the introduction of surgical intervention for patients with TOF in 1945, surgical management of TOF has dramatically improved early survival with mortality rates, less than 2-3%. However, the majority of these patients continue to experience residual right ventricular outflow tract pathology, most commonly pulmonary valve regurgitation (PR). The patients are generally asymptomatic during childhood and adolescence and, however, are at risk for severe PR later which can result in exercise intolerance, heart failure, arrhythmias, and sudden death...
May 19, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29778240/the-autonomic-neural-mechanism-of-right-ventricular-outflow-tract-tachycardia
#2
Hung-Yu Chang, Li-Wei Lo, Yu-Ruey Chen, Yu-Hui Chou, Wei-Lun Lin, Yenn-Jiang Lin, Wei-Hsian Yin, An-Ning Feng, Shih-Ann Chen
BACKGROUND: Ventricular tachycardia (VT) and ventricular premature complexes (VPCs) originating from the right ventricular outflow tract (RVOT) are generally considered as benign arrhythmias, with ECG morphology showing LBBB pattern and inferior axis. Pathogenic mechanisms in the genesis of RVOT VT/VPC remain largely unknown. We aimed to investigate the neural mechanism in RVOT ventricular arrhythmias in canine model. METHODS: Twelve mongrel dogs (13.7 ± 1...
July 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29776810/congenital-heart-disease-in-adults-assessmentof-functional-capacity-using-cardiopulmonary-exercise-testing
#3
Sílvia Aguiar Rosa, Ana Agapito, Rui M Soares, Lídia Sousa, José Alberto Oliveira, Ana Abreu, Ana Sofia Silva, Sandra Alves, Helena Aidos, Fátima F Pinto, Rui Cruz Ferreira
AIM: The aim of the study was to compare functional capacity in different types of congenital heart disease (CHD), as assessed by cardiopulmonary exercise testing (CPET). METHODS: A retrospective analysis was performed of adult patients with CHD who had undergone CPET in a single tertiary center. Diagnoses were divided into repaired tetralogy of Fallot, transposition of the great arteries (TGA) after Senning or Mustard procedures or congenitally corrected TGA, complex defects, shunts, left heart valve disease and right ventricular outflow tract obstruction...
May 15, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29765618/mediastinal-monophasic-synovial-sarcoma-with-pericardial-extension-causing-hemodynamic-instability
#4
Habib R Khan, Mohammad I Ansari, Andrew P Thain, Sadia Abdullah, Ramya Parasa, Richard W Varcoe
A 46-year-old man presented with mass on chest x-ray along with a 6-month history of weight loss, dyspnea and cough. He was hypotensive and an echocardiogram showed large extra-cardiac mass compressing the right ventricular outflow tract resulting in features of cardiac tamponade. Chest computed tomography revealed a mediastinal mass invading the pericardium adjacent to right ventricular outflow tract. Biopsy of the mass confirmed primary monophasic synovial sarcoma. Chemotherapy and radiotherapy along with anti-inflammatories were given as surgery was too high risk due to the location of the tumour and pericardial involvement...
May 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29761247/beneficial-effects-of-fenofibrate-in-pulmonary-hypertension-in-rats
#5
Palak Galhotra, Pankaj Prabhakar, Himanshu Meghwani, Soheb A Mohammed, Sanjay Kumar Banerjee, Sandeep Seth, Milind P Hote, K H Reeta, Ruma Ray, Subir Kumar Maulik
Pulmonary hypertension (PH) is a morbid complication of cardiopulmonary as well as several systemic diseases in humans. It is rapidly progressive and fatal if left untreated. In the present study, we investigated the effect of PPARα agonist fenofibrate (FF) on monocrotaline (MCT)-induced PH in rats. FF, because of its pleiotropic property, could be helpful in reducing inflammation, oxidative stress, and reactive oxygen species. On day 1, MCT (50 mg/kg, s.c.) was given to all the rats in MCT, sildenafil, and FF group except normal control rats...
May 14, 2018: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29759536/value-of-a-posterior-electrocardiographic-lead-for-localization-of-ventricular-outflow-tract-arrhythmias-the-v-4-v-8-ratio
#6
Fengxiang Zhang, David Hamon, Zhen Fang, Yan Xu, Bing Yang, Weizhu Ju, Jason Bradfield, Kalyanam Shivkumar, Minglong Chen, Roderick Tung
OBJECTIVES: This study sought to prospectively evaluate the value of a dedicated electrocardiographic posterior lead to create an anteroposterior ratio to localize premature ventricular complexes (PVCs) between the right ventricular outflow tract and left ventricular outflow tract for catheter ablation. BACKGROUND: The anteroposterior relationship between the right and left outflow tract has not been explored for electrocardiographic localization of ventricular arrhythmia...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759535/utility-of-conventional-electrocardiographic-criteria-in-patients-with-idiopathic-ventricular-tachycardia
#7
Anil V Yadav, Babak Nazer, Barbara J Drew, John M Miller, Hicham El Masry, William J Groh, Andrea Natale, Nassir Marrouche, Nitish Badhwar, Yanfei Yang, Melvin M Scheinman
OBJECTIVES: This study sought to determine the ability of conventional electrocardiographic (ECG) criteria to correctly differentiate idiopathic ventricular tachycardia (VT) from supraventricular tachycardia (SVT) with aberrancy. BACKGROUND: Previously reported VT ECG criteria were developed from cohorts of patients with structural heart disease and have not been applied to patients with idiopathic VT. METHODS: ECGs of 115 idiopathic VTs, 101 post-myocardial infarction (MI) VTs, and 111 wide QRS SVTs were analyzed using standard criteria...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759533/12-lead-electrocardiogram-to-localize-region-of-abnormal-electroanatomic-substrate-in-arrhythmogenic-right-ventricular-cardiomyopathy
#8
Cory M Tschabrunn, Haris M Haqqani, Pasquale Santangeli, Erica S Zado, Francis E Marchlinski
OBJECTIVES: The purpose of this study was to evaluate the relationship between electrocardiogram (ECG) QRS fragmentation (fQRS) and right ventricular (RV) endocardial (ENDO) and epicardial (EPI) electroanatomic substrate abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). BACKGROUND: fQRS is frequently observed in patients with ARVC and reflects delayed conduction due to RV fibrosis. METHODS: A total of 30 consecutive patients met the task force criteria for ARVC (19 men, mean age 41...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29750433/absence-of-a-primary-role-for-ttn-missense-variants-in-arrhythmogenic-cardiomyopathy-from-a-clinical-and-pathological-perspective
#9
Kai Chen, Jiangping Song, Zhen Wang, Man Rao, Liang Chen, Shengshou Hu
BACKGROUND: Arrhythmogenic cardiomyopathy (ACM) is an inheritable heart disease characterized by fibro-fatty replacement of the myocardium. TTN missense variants were previously reported as a pathogenic factor for ACM. HYPOTHESIS: TTN missense variants are commonly identified in ACM, but have limited effect on the phenotype of ACM. METHODS: We sequenced 15 ACM-related genes in 35 patients who had a heart transplantation and quantified myocardium, and fibrous and adipose tissue in blocks of the explanted heart...
May 11, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29740728/transvenous-cardiac-implantable-electronic-device-implantation-in-patients-with-persistent-left-superior-vena-cava-in-a-tertiary-center
#10
Xueying Chen, Ziqing Yu, Jin Bai, Wei Wang, Shengmei Qin, Jingfeng Wang, Zhe Sun, Fei Han, Yangang Su, Junbo Ge
PURPOSE: Persistent left superior vena cava (PLSVC) is rare and often asymptomatic, which might cause difficulties in the implantation of cardiac implantable electronic devices (CIEDs). The aim of this study was to determine the prevalence of PLSVC and to study the clinical characteristics and significance of PLSVC in patients with CIED implantation. METHODS: Thirty-three patients with PLSVC were collected from 7047 CIED recipients over recent 10 years in our center...
May 9, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29737447/predicting-value-of-coupling-interval-variability-in-determining-the-origin-of-ventricular-premature-contractions-with-v3-transition
#11
Umut Celikyurt, Aysen Agir, Irem Karauzum, Kurtulus Karauzum, Tayfun Sahin, Ahmet Vural
PURPOSE: We aimed to investigate the predictive value of coupling interval variability (ΔCI) in determining the origin of idiopathic outflow tract ventricular tachycardia (OTVT) with V3 transition. METHODS: We reviewed data from 126 patients who underwent catheter ablation of OTVT between 2015 and 2018 at our institution. We identified 32 patients of successful OTVT ablation with a precordial transition at V3 derivation. The ΔCI (maximum - minimum CI) was measured...
May 8, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29735255/computed-tomography-predictors-of-mortality-stroke-and-conduction-disturbances-in-women-undergoing-tavr-a-sub-analysis-of-the-win-tavi-registry
#12
Marco Spaziano, Alaide Chieffo, Yusuke Watanabe, Jaya Chandrasekhar, Samantha Sartori, Thierry Lefèvre, Anna Sonia Petronio, Patrizia Presbitero, Didier Tchetche, Alessandro Iadanza, Nicholas M Van Mieghem, Julinda Mehilli, Roxana Mehran, Marie-Claude Morice
BACKGROUND: Aortic valve calcification patterns were associated with short- and long-term outcomes in previous small observational datasets of patients undergoing transcatheter aortic valve implantation (TAVI). The specific impact of multi detector-row computed tomography (MDCT) findings on outcomes in women has not been reported. We sought to describe the associations between MDCT characteristics and clinical outcomes in a registry of 547 women undergoing TAVI. METHODS: WIN-TAVI is the first all-female registry to study the safety and effectiveness of TAVI in women (n = 1019)...
April 27, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29733826/pulmonary-valve-replacement-a-single-institution-comparison-of-surgical-and-transcatheter-valves
#13
Vikas Sharma, Eric R Griffiths, Aaron W Eckhauser, Robert G Gray, Mary H Martin, Chong Zhang, Angela P Presson, Phillip T Burch
BACKGROUND: Transcatheter pulmonary valve replacement (TPVR) is increasingly utilized to address residual or recurrent right ventricular outflow tract pathology in congenital heart disease patients. We aimed to evaluate clinical outcomes and resource utilization comparing TPVR to surgical pulmonary valve replacement (SPVR) for this patient population. METHODS: From January 2010 until December 2015, 224 patients underwent pulmonary valve replacement (SPVR n=100 and TPVR n=124)...
May 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29727513/unipolar-voltage-mapping-criteria-for-septal-aspect-of-right-ventricular-influence-of-aortic-root
#14
Iosif Kelesidis, Benoit Desjardins, Daniele Muser, Pasquale Santangeli, Erica S Zado, Francis E Marchlinski
INTRODUCTION: Unipolar voltage mapping through its wider "field of view" can identify substrate deeper to the endocardium on the right ventricular (RV) free wall and left ventricle. The reference value(s) for normal endocardial (ENDO) unipolar voltage (UNI) for the septal aspect of the right ventricle (RV) and the effect of the aortic root that is directly opposed to the posterior septal plane of the RV outflow tract (RVOT) have not been established. METHODS AND RESULTS: We performed detailed (185 ± 70, range 127-342 points) RV ENDO UNI maps in 9 patients without structural heart disease; 6 had magnetic resonance (MR) imaging; 5 were males; the mean age was 49 ± 11 years...
May 4, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29724567/infective-endocarditis-after-percutaneous-pulmonary-valve-implantation-a-long-term-single-centre-experience
#15
Daniel Tanase, Peter Ewert, Alfred Hager, Stanimir Georgiev, Julie Cleuziou, John Hess, Andreas Eicken
BACKGROUND: Patients with congenital cardiovascular disease involving the right ventricular outflow tract and with prosthetic valves in the heart are at high risk for developing infective endocarditis (IE). Recently, there has been concern about relatively high rates of IE after percutaneous pulmonary valve implantation (PPVI). Although there are factors specific to percutaneous valves that could plausibly contribute to the risk of IE, including procedural steps prior to implantation such as crimping the valved stent or mechanical forces during dilation, little is known about actual risk factors for this complication...
April 22, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29722855/clinical-research-remote-magnetic-navigation-vs-manually-controlled-catheter-ablation-of-right-ventricular-outflow-tract-arrhythmias-a-retrospective-study
#16
Ayelet Shauer, Lennart J De Vries, Ferdi Akca, Jorge Palazzolo, Mohammed Shurrab, Ilan Lashevsky, Irving Tiong, Sheldon M Singh, David Newman, Tamas Szili-Torok, Eugene Crystal
Aims: Remote magnetic navigation (RMN) is an alternative to manual catheter control (MCC) radiofrequency ablation of right ventricular outflow tract (RVOT) arrhythmias. The data to support RMN approach is limited. We aimed to investigate the clinical and procedural outcomes in a cohort of patients undergoing RVOT premature ventricular complex/ventricular tachycardia (PVCs/VT) ablation procedures using RMN vs. MCC. Methods and results: Data was collected from two centres...
May 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29720396/primary-repair-versus-surgical-and-transcatheter-palliation-in-infants-with-tetralogy-of-fallot
#17
Dan M Dorobantu, Alireza S Mahani, Mansour T A Sharabiani, Ragini Pandey, Gianni D Angelini, Andrew J Parry, Robert M R Tulloh, Robin P Martin, Serban C Stoica
OBJECTIVES: Treatment of infants with tetralogy of Fallot (ToF) has evolved in the last two decades with increasing use of primary surgical repair (PrR) and transcatheter right ventricular outflow tract palliation (RVOTd), and fewer systemic-to-pulmonary shunts (SPS). We aim to report contemporary results using these treatment options in a comparative study. METHODS: This a retrospective study using data from the UK National Congenital Heart Disease Audit. All infants (n=1662, median age 181 days) with ToF and no other complex defects undergoing repair or palliation between 2000 and 2013 were considered...
May 2, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29717777/syncope-and-right-sided-heart-failure-due-to-right-ventricular-outflow-tract-obstruction-by-giant-sinus-of-valsalva-aneurysm
#18
Umut Kocabas, Guzin Zekican, Gulgun Vaiz, Naciye Ozbek, Cenk Conkbayır
No abstract text is available yet for this article.
2018: Cardiology Journal
https://www.readbyqxmd.com/read/29716710/catheter-ablation-for-electrical-storm-in-brugada-syndrome-results-of-substrate-based-ablation
#19
Abhijeet Shelke, Ajit Tachil, Daljeet Saggu, Masilamani Lawrance Jesuraj, Sachin Yalagudri, Calambur Narasimhan
BACKGROUND: Brugada syndrome (BrS) is known to cause malignant ventricular arrhythmia (VA) and sudden cardiac death (SCD). Patients with implantable cardioverter defibrillator (ICD) may experience recurrent shocks from ICD. Recent reports indicate that radiofrequency ablation (RFA) in BrS is feasible, and effective. Catheter ablation of premature ventricular complexes (PVCs) triggering VA and substrate modification of right ventricular outflow tract (RVOT) has been described. METHODS AND RESULTS: Five patients (4 males, age-23 to 32 years) with BrS and electrical storm (ES) despite being on isoprenaline infusion and cilostazol (phosphodiestrase-3 inhibitor) underwent 3 dimensional electroanatomic mapping and RFA...
March 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29715702/incidence-and-risk-factors-for-right-ventricular-outflow-tract-obstruction-after-the-arterial-switch-operation
#20
Julie Cleuziou, Keti Vitanova, Jelena Pabst von Ohain, Masamichi Ono, Daniel Tanase, Melchior Burri, Rüdiger Lange
BACKGROUND:  The aim of this study was to evaluate the incidence and risk factors for the development of right ventricular outflow tract obstruction (RVOTO) after the arterial switch operation (ASO). METHODS:  Between 1983 and 2014, a total of 688 patients underwent ASO. RVOTO was defined as any obstruction of the right ventricular outflow tract (RVOT) requiring reintervention. RESULTS:  RVOTO developed in 79 patients (11%) at a median time of 3...
May 1, 2018: Thoracic and Cardiovascular Surgeon
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