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G Borges, C L Bagge, C J Cherpitel, K R Conner, R Orozco, I Rossow
BACKGROUND: No review has used a meta-analytic approach to estimate common odds ratios (ORs) for the effect of acute use of alcohol (AUA) on suicide attempts. We aim to report the results of the first meta-analysis of controlled epidemiological studies on AUA and suicide attempt. METHOD: The English-language literature on Medline, PsycINFO and Google Scholar was searched for original articles and critical review on AUA and suicide attempt (period 1996-2015). Studies had to report an OR estimate for this association...
December 8, 2016: Psychological Medicine
O Laccourreye, A Werner, L Laccourreye, P Bonfils
OBJECTIVES: To elucidate the benefits, pitfalls and risks of phytotherapy in the clinical practice of otorhinolaryngology. MATERIAL AND METHODS: The PubMed and Cochrane databases were searched using the following keywords: phytotherapy, phytomedicine, herbs, otology, rhinology, laryngology, otitis, rhinitis, laryngitis and otorhinolaryngology. Seventy-two articles (18 prospective randomized studies, 4 Cochrane analyses, 4 meta-analysis and 15 reviews of the literature) devoted to clinical studies were analyzed...
November 30, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Cristiane Mariote Amaral, Alice Marques Diniz, Eugênio Braz Rodrigues Arantes, Glauco Botelho Dos Santos, Jaime Dutra Noronha-Filho, Eduardo Moreira da Silva
PURPOSE: To investigate the influence of 4-META concentration and type of solvent on the degree of conversion (DC%) and resin-dentin bond stability of experimental etch-and-rinse adhesives. MATERIALS AND METHODS: Four different concentrations of 4-META (12 wt%, 20 wt%, 30 wt%, 40 wt%) were added to a model adhesive system consisting of TEG-DMA (25 wt%), UDMA (20 wt%), HEMA (30 wt%), water (4 wt%), camphorquinone (0.5 wt%), and tertiary amine (0.5 wt%) dissolved in 20% acetone (A12, A20, A30 and A40) or 20% ethanol (E12, E20, E30 and E40)...
November 18, 2016: Journal of Adhesive Dentistry
Paul D Madge, Andrea Maggioni, Mauro Pascolutti, Moein Amin, Mario Waespy, Bernadette Bellette, Robin J Thomson, Sørge Kelm, Mark von Itzstein, Thomas Haselhorst
Siglec-2 undergoes constitutive endocytosis and is a drug target for autoimmune diseases and B cell-derived malignancies, including hairy cell leukaemia, marginal zone lymphoma, chronic lymphocytic leukaemia and non-Hodgkin's lymphoma (NHL). An alternative to current antibody-based therapies is the use of liposomal nanoparticles loaded with cytotoxic drugs and decorated with Siglec-2 ligands. We have recently designed the first Siglec-2 ligands (9-biphenylcarboxamido-4-meta-nitrophenyl-carboxamido-Neu5Acα2Me, 9-BPC-4-mNPC-Neu5Acα2Me) with simultaneous modifications at C-4 and C-9 position...
November 3, 2016: Scientific Reports
Stephen Lutz, Tracy Balboni, Joshua Jones, Simon Lo, Joshua Petit, Shayna E Rich, Rebecca Wong, Carol Hahn
PURPOSE: The purpose is to provide an update the Bone Metastases Guideline published in 2011 based on evidence complemented by expert opinion. The update will discuss new high-quality literature for the 8 key questions from the original guideline and implications for practice. METHODS AND MATERIALS: A systematic PubMed search from the last date included in the original Guideline yielded 414 relevant articles. Ultimately, 20 randomized controlled trials, 32 prospective nonrandomized studies, and 4 meta-analyses/pooled analyses were selected and abstracted into evidence tables...
January 2017: Practical Radiation Oncology
Kanae Wada, Eri Ikeda, Junichiro Wada, Go Inoue, Munenaga Miyasaka, Michiyo Miyashin
Although the demand for aesthetic restoration of primary molars has increased, the full-crown restorations using resin and the details of the wear characteristics of trimethylolpropane trimethacrylate (TMPT) filler containing resins for primary molars are not well understood. This study was conducted to determine whether new light-cured composite resin (Fantasista) and 4-META/MMATBB resin (Bondfill SB) are appropriate for full crown restoration of primary molars by evaluating their wear characteristics. Both resins products contain TMPT filler...
2016: Dental Materials Journal
Morakot Piemjai, Mutlu Özcan, Franklin Garcia-Godoy, Nobuo Nakabayashi
This study evaluated the conditions of the non-invasive resin-bonded fixed dental prostheses (FDP) and patient satisfaction up to 10 years of clinical function. A total of 23 patients who required fixed prostheses in the areas of mandibular anterior and premolar, and maxillary anterior region received resin-bonded restorations between 1999-2003. In 13 patients with 14 edentulous areas were restored with an adhesive pontic (natural tooth, acrylic and porcelain). Two indirect proximal veneers using resin composite were placed in each space in 10 patients having 13 edentulous spaces...
June 2016: European Journal of Prosthodontics and Restorative Dentistry
Junichi Shinagawa, Go Inoue, Toru Nikaido, Masaomi Ikeda, Alireza Sadr, Junji Tagami
The purpose of this study was to evaluate bonding performance and dentin interface acid resistance using a 4-META/MMA-TBB based restorative material (BF) compared to a conventional 4-META/MMA-TBB resin cement (SB), and the effect of sodium fluoride (NaF) addition to the materials. Dentin surfaces were treated with 10% citric acid-3% ferric chloride (10-3) or 4-META containing self-etching primer (TP), followed by application of BF or SB polymer powders with or without NaF, to evaluate microtensile bond strength (µTBS) in six experimental groups; 10-3/SB, 10-3/BF, TP/SB, TP/BF, TP/SB/NaF and TP/BF/NaF...
July 30, 2016: Dental Materials Journal
Ippei Hamanaka, Hiroshi Shimizu, Yutaka Takahashi
PURPOSE: This study evaluated the shear bond strength of a chairside autopolymerizing reline resin to injection-molded thermoplastic denture base resins. METHODS: Four kinds of injection-molded thermoplastic resins (two polyamides, a polyethylene terephthalate copolymer and a polycarbonate) and PMMA, as a control, were tested. The eight types of surface treatment: ((1) no treatment, (2) air abrasion, (3) dichloromethane, (4) ethyl acetate, (5) 4-META/MMA-TBB resin, (6) air abrasion and 4-META/MMA-TBB resin, (7) tribochemical silica coating, and (8) tribochemical silica coating and 4-META/MMA-TBB resin) were applied to each specimen...
May 26, 2016: Journal of Prosthodontic Research
Christina Abdel Shaheed, Chris G Maher, Kylie A Williams, Richard Day, Andrew J McLachlan
IMPORTANCE: Opioid analgesics are commonly used for low back pain, however, to our knowledge there has been no systematic evaluation of the effect of opioid dose and use of enrichment study design on estimates of treatment effect. OBJECTIVE: To evaluate efficacy and tolerability of opioids in the management of back pain; and investigate the effect of opioid dose and use of an enrichment study design on treatment effect. DATA SOURCES: Medline, EMBASE, CENTRAL, CINAHL, and PsycINFO (inception to September 2015) with citation tracking from eligible randomized clinical trials (RCTs)...
July 1, 2016: JAMA Internal Medicine
Young Ho Lee, Gwan Gyu Song
OBJECTIVES: The aim of this study was to determine whether the FAS, and FASL polymorphisms are associated with susceptibility to systemic lupus erythematosus (SLE). METHODS: A meta-analysis was conducted on the associations between the FAS -670 A/G, FAS -1377 G/A, and FASL -844 T/C polymorphisms and SLE. RESULTS: A total of eleven articles met the study inclusion criteria. Meta-analysis indicated an association between SLE and the FAS -670 A/G polymorphism in the dominant model (OR=0...
July 2016: Clinical and Experimental Rheumatology
Takahiko Morotomi, Shizu Hirata-Tsuchiya, Ayako Washio, Chiaki Kitamura
PURPOSE: To assess the effects of different curing stages of 4-META/MMA-TBB resin on osteoblasts and gingival keratinocytes. MATERIALS AND METHODS: The MC3T3-E1 murine pre-osteoblastic cell line and GE-1 murine gingival epithelial cell line were cultured with mixtures of Super-Bond C&B at different curing stages, and the cell viability was assessed. The alkaline phosphatase (ALP) activity of the MC3T3-E1 cells was also assessed. RESULTS: The majority of the MC3T3-E1 cells died and showed no ALP activity when cultured with 4-META/MMA-TBB resin during the initial curing phase (1 min of curing)...
2016: Journal of Adhesive Dentistry
Masao Hanabusa, Kumiko Yoshihara, Yasuhiro Yoshida, Takumi Okihara, Takatsugu Yamamoto, Yasuko Momoi, Bart Van Meerbeek
The degree of conversion (DC) of camphorquinone/amine-based adhesives is affected by acidic functional monomers as a result of inactivation of the amine co-initiator through an acid-base reaction. During bonding, functional monomers of self-etch adhesives chemically interact with hydroxyapatite (HAp). Here, we tested in how far the latter interaction of functional monomers with HAp counteracts the expected reduction in DC of camphorquinone/amine-based adhesives. The DC of three experimental adhesive formulations, containing either of the two functional monomers [10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) or 4-methacryloxyethyl trimellitic acid anhydride (4-META)] or no functional monomer (no-FM; control), was measured with and without HAp powder added to the adhesive formulations...
April 2016: European Journal of Oral Sciences
Ravi Varshney, Matthew J Budoff
BACKGROUND: Thousands of studies have been published based on animal and human studies evaluating garlic's effects and safety. OBJECTIVE: We reviewed the available literature investigating the effects of garlic supplements on hypertension, hypercholesterolemia, C-reactive protein (CRP), pulse wave velocity (PWV), and coronary artery calcium (CAC), as well as available data on side effects. METHODS: We searched PubMed for all human studies using medical subject heading words through 30 May 2013 and assessed relevant review articles and original studies...
February 2016: Journal of Nutrition
You Li, Chunjie Li, Jun Sun, Li Ye, Yi Su, Longjiang Li
OBJECTIVE: To evaluate the diagnostic value of magnetic resonance (MR) imaging in the diagnosis of mandibular invasion caused by oral cancers. METHODS: Medline, EMBASE, SIGLE, and Chinese biomedical literature database were searched electronically. Manual searching for 19 relevant Chinese journals was also performed. Two reviewers evaluated the literature and extracted the data. Meta-Disc 1.4 was chosen to conduct the sensitivity (SEN), specificity (SPE), and 95% confidence interval (95%CI)...
August 2015: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
Alfredo Guarino, Stefano Guandalini, Andrea Lo Vecchio
Probiotics are increasingly used for prevention and treatment of diarrhea more in children than in adults. Given the broad spectrum of diarrhea, this review focuses on the main etiologies: acute gastroenteritis, antibiotic-associated diarrhea (AAD), and necrotizing enterocolitis (NEC). For each, we reviewed randomized controlled trials, meta-analyses, and guidelines. For acute gastroenteritis we found 12 guidelines: 5 recommended probiotics and 7 did not. However, the guidelines containing positive recommendations provided proof of evidence from clinical trials and meta-analyses...
November 2015: Journal of Clinical Gastroenterology
John Protzko, Joshua Aronson, Clancy Blair
Can interventions meaningfully increase intelligence? If so, how? The Database of Raising Intelligence is a continuously updated compendium of randomized controlled trials that were designed to increase intelligence. In this article, the authors examine nearly every available intervention involving children from birth to kindergarten, using meta-analytic procedures when more than 3 studies tested similar methods and reviewing interventions when too few were available for meta-analysis. This yielded 4 meta-analyses on the effects of dietary supplementation to pregnant mothers and neonates, early educational interventions, interactive reading, and sending a child to preschool...
January 2013: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
Ayumi Takano, Yuki Miyamoto, Toshihiko Matsumoto
PURPOSE: Over the past two decades, computerized and Internet-based interventions for the treatment of various health problems, including substance abuse, have been developed and used to resolve treatment-related issues. The purpose of this study is to review selected studies that conducted computerized and Internet-based psychosocial interventions for people with drug-use problems. METHODS: We used a PubMed search to identify relevant studies to our review based on the following inclusion criteria: 1) the study participants were drug users; 2) the Internet or computer technologies were used for the interventions; 3) the study used psychosocial interventions; and 4) meta-analysis and randomized controlled trial (RCT)...
February 2015: Nihon Arukōru Yakubutsu Igakkai Zasshi, Japanese Journal of Alcohol Studies & Drug Dependence
Stefan T Engelter, Christopher Traenka, Alexander Von Hessling, Philippe A Lyrer
Cervical artery dissection (CAD) is a major cause of stroke in the young. A mural hematoma is detected in most CAD patients. The intramural blood accumulation should not be considered a reason to withhold intravenous thrombolysis in patients with CAD-related stroke. Because intravenous-thrombolyzed CAD patients might not recover as well as other stroke patients, acute endovascular treatment is an alternative. Regarding the choice of antithrombotic agents, this article discusses the findings of 4 meta-analyses across observational data, the current status of 3 randomized controlled trials, and arguments and counterarguments favoring anticoagulants over antiplatelets...
May 2015: Neurologic Clinics
Naohisa Kohda, Masahiro Iijima, Kyotaro Kawaguchi, Hirokazu Toshima, Takeshi Muguruma, Kazuhiko Endo, Itaru Mizoguchi
We investigated the enamel demineralization-prevention ability and shear bond strength (SBS) properties of 4-methacryloxyethyl trimellitic anhydride/methyl methacrylate-tri-n-butyl borane (4-META/MMA-TBB)-based resin containing various amounts (0-50%) of bioactive glass (BG). Disk-shaped specimens were immersed in distilled water and ions released were analysed by inductively coupled plasma atomic-emission spectroscopy. Samples were also immersed in lactic acid solution (pH 4.6) to estimate acid-neutralizing ability...
June 2015: European Journal of Oral Sciences
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