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Adrian Mendez, Alex Hopkins, Vincent L Biron, Hadi Seikaly, Lin Fu Zhu, David W J Côté
BACKGROUND: Recent studies have examined the effects of brief electrical stimulation (BES) on nerve regeneration, with some suggesting that BES accelerates facial nerve recovery. However, the facial nerve outcome measurement in these studies has not been precise or accurate. Furthermore, no previous studies have been able to demonstrate the effect of BES on synkinesis. The objective of this study is to examine the effect of brief electrical stimulation (BES) on facial nerve function and synkinesis in a rat model...
March 7, 2018: Journal of Otolaryngology—Head & Neck Surgery
Çağdaş Topçu, Hilmi Uysal, Ömer Özkan, Özlenen Özkan, Övünç Polat, Merve Bedeloğlu, Arzu Akgül, Ela Naz Döğer, Refik Sever, Ömer Halil Çolak
BACKGROUND: We assessed the recovery of 2 face transplantation patients with measures of complexity during neuromuscular rehabilitation. Cognitive rehabilitation methods and functional electrical stimulation were used to improve facial emotional expressions of full-face transplantation patients for 5 months. Rehabilitation and analyses were conducted at approximately 3 years after full facial transplantation in the patient group. We report complexity analysis of surface electromyography signals of these two patients in comparison to the results of 10 healthy individuals...
March 6, 2018: Journal of Neuroengineering and Rehabilitation
Ye Tu, Feng Gao
RATIONALE: Levator resection has become a routine procedure for patients with severe Marcus Gunn jaw-winking synkinesis (MGJWS). To optimize the surgical outcome, adult patients need to be kept awake, or easily aroused and responsive to verbal commands during the operation. However, levator resection is commonly performed under general anesthesia in pediatric patients. In the present case, we described a successful anesthetic protocol of conscious sedation with local anesthesia for levator resection in a child...
December 2017: Medicine (Baltimore)
Lilli Cooper, Charles Izard, Victoria Harries, Catriona Neville, Vanessa Venables, Raman Malhotra, Charles Nduka
BACKGROUND: Aberrant reinnervation and synkinesis are common and debilitating after facial palsy. Paradoxical frontalis activation can antagonize eye closure and increase the risk of corneal damage. If recognized, judicious botulinum toxin injection to the affected side may reduce this risk. METHODS: One hundred consecutive patients with synkinesis were identified from a prospective database. Routine facial view photographs were converted to a standardized scale using iris diameter...
February 2018: Plastic and Reconstructive Surgery
R Jun Lin, Libby J Smith, Michael C Munin, Shaum Sridharan, Clark A Rosen
OBJECTIVE: Treatment options for symptomatic unilateral vocal fold paralysis (VFP) include vocal fold augmentation, laryngeal framework surgery, and laryngeal reinnervation. Laryngeal reinnervation (LR) has been suggested to provide "tone" to the paralyzed VF. This implies a loss of tone as a result of denervation without reinnervation. We performed laryngeal electromyography (LEMG) in patients with chronic VFP to understand the innervation status associated with a chronically paralyzed vocal fold...
January 22, 2018: Laryngoscope
Sertac Yetiser
Hypoglossal-facial anastomosis provides excellent motor supply to the mimetic muscles of the face when there is no chance of recovery of the damaged facial nerve. However, to achieve optimal results, the timing of facial nerve surgery based on electrophysiological testing and clinical evaluation requires close follow-up of the patient. Functional results after delayed surgery are not predictable and depend on the number of surviving fibers, type of injury, severity of damage, degree of infiltration of inflammatory cells, and local fibrosis...
December 27, 2017: Journal of Craniofacial Surgery
I V Reshetov, G V Polunin, A V Ananichuk, L I Ippolitov, A A Kovalenko
The restoration of the functional competence of the larynx following bilateral laryngeal nerve damage and vocal fold paralysis is a serious challenge for the surgeon that has thus far no satisfactory solution. Physiological re-innervation that occurs naturally with time is non-selective and, in the majority of the cases, leads to synkinesis. Laryngeal pacing achieved with the application of the implantable microchips appears to be a promising approach. The animal experiments have demonstrated the possibility of successful restoration of all the functions of the larynx by means of laryngeal pacing but simultaneously revealed a number of technical issues that have to be addressed if the further progress in this field is to be achieved including the choice of the proper materials for implantation, solution of problems pertaining to the neuromuscular mapping during pacer implantation, etc...
2017: Vestnik Otorinolaringologii
Mauro Tarallo, Magda Gharbiya, Maria Giuseppina Onesti, Andrea Conversi, Marco Toscani, Pasquale Fino, Nicolò Scuderi, Giuseppe Di Taranto
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
Arif O Khan, Zabila Khan
Congenital cranial dysinnervation disorders are developmental abnormalities of cranial nerves that often include abnormal synkinesis. Among the most common ophthalmic congenital cranial dysinnervation disorders are Duane retraction syndrome and the Marcus-Gunn jaw-winking phenomenon. This report documents gustatory lid retraction as an unusual congenital cranial dysinnervation.
December 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Keishi Fujiwara, Yasushi Furuta, Naoko Yamamoto, Kanako Katoh, Satoshi Fukuda
OBJECTIVE: To investigate factors affecting the effect of physical rehabilitation therapy for synkinesis as a sequela to facial nerve palsy. METHODS: A total of 37 patients with peripheral facial nerve palsy in Teine-Keijinkai Hospital were enrolled in this study. All patients showed synkinesis at 6 months after the onset of facial nerve palsy and were instructed in physical rehabilitation by expert staff from their first visit. The degree of synkinesis was evaluated at 6, 9 and 12 months after the onset of facial nerve palsy based on Sunnybrook facial grading system score and asymmetry in eye opening width...
October 31, 2017: Auris, Nasus, Larynx
Phuong Thi Thanh Nguyen, Shailja Tibrewal, Suma Ganesh
Aberrant regeneration of the third nerve following its palsy is commonly seen after trauma and compressive lesions. This phenomenon is thought to result due to misdirection of the regenerating axons. Surgical management is a great challenge in the third nerve palsy owing to multiple muscle involvement and is often accompanied by ptosis and poor Bell's phenomenon. We present a case of a 27-year-old male who developed isolated complete third nerve palsy of the left eye following head trauma. Features of aberrant regeneration were seen after 6 months, namely, inverse Duane's sign and Pseudo-Von Graefe's sign...
October 2017: Indian Journal of Ophthalmology
Aaron M Kosins, Peter Palhazi
No abstract text is available yet for this article.
September 1, 2017: Aesthetic Surgery Journal
Giuseppe Guarro, Francesco Brunelli, Barbara Rasile, Carmine Alfano
Background: Synkinesis represents involuntary muscular movements that occur in association with voluntary contraction of other muscle groups. Oculonasal synkinesis is a rare phenomenon. Objectives: In a series of videos, the authors present clinical findings and surgical correction of oculonasal synkinesis. Methods: Two women who underwent surgical procedures to correct oculonasal synkinesis were evaluated in a prospective study. One patient presented with bilateral synkinesis after 2 previous rhinoplasties...
September 1, 2017: Aesthetic Surgery Journal
Federico Biglioli, Otilija Kutanovaite, Dimitri Rabbiosi, Giacomo Colletti, M A S Mohammed, Alberto M Saibene, Silvia Cupello, Antonino Privitera, Valeria M A Battista, Alessandro Lozza, Fabiana Allevi
Synkinetic movements are common among patients with incomplete recovery from facial palsy, with reported rates ranging from 9.1% to almost 100%. The authors propose the separation of the neural stimulus of the orbicularis oculi from that of the zygomatic muscular complex to treat eyelid closure/smiling synkinesis. This technique, associated with an anastomosis between the masseteric nerve and a central branch of the facial nerve, as well as with the use of a cross-facial nerve graft, resolves most of the spasms of the midface musculature, leading to a more relaxed tone when the mimic muscle is at rest and enhancing muscle excursion during voluntary and spontaneous smiling...
December 2017: Journal of Cranio-maxillo-facial Surgery
Verena Meier-Gallati, Henning Scriba
The objective of this paper is to assess synkinesis associated with post paretic voluntary facial movements using the objective OSCAR method and to investigate the correlation between synkinesis and paresis to compare the objective results with the subjective scaling systems of Fisch and House-Brackmann. The development of an objective assessment of synkinesis with the OSCAR method is focused on the clinically most relevant eye-mouth and forehead-mouth synkinetic movements. Thirteen patients with unilateral facial paralysis and synkinesis of the University Hospital Zurich were examined...
December 2017: European Archives of Oto-rhino-laryngology
Mihail A Akulov, Ol'ga R Orlova, Aleksandra S Orlova, Dmitrij J Usachev, Vadim N Shimansky, Sergey V Tanjashin, Svetlana E Khatkova, Anna V Yunosha-Shanyavskaya
BACKGROUND: This study evaluates the effect of incobotulinumtoxinA in the acute and chronic phases of facial nerve palsy after neurosurgical interventions. METHODS: Patients received incobotulinumtoxinA injections (active treatment group) or standard rehabilitation treatment (control group). Functional efficacy was assessed using House-Brackmann, Yanagihara System and Sunnybrook Facial Grading scales, and Facial Disability Index self-assessment. RESULTS: Significant improvements on all scales were seen after 1month of incobotulinumtoxinA treatment (active treatment group, р<0...
October 15, 2017: Journal of the Neurological Sciences
Priyesh N Patel, Scott R Owen, Cathey P Norton, Brandon T Emerson, Andrea B Bronaugh, William R Ries, Scott J Stephan
Importance: The buccinator, despite being a prominent midface muscle, has been previously overlooked as a target in the treatment of facial synkinesis with botulinum toxin. Objective: To evaluate outcomes of patients treated with botulinum toxin to the buccinator muscle in the setting of facial synkinesis. Design, Setting, and Participants: Prospective cohort study of patients who underwent treatment for facial synkinesis with botulinum toxin over multiple treatment cycles during a 1-year period was carried out in a tertiary referral center...
September 28, 2017: JAMA Facial Plastic Surgery
Andrew J Thomas, Michael O Larson, Samuel Braden, Richard B Cannon, P Daniel Ward
Importance: Botulinum toxin neuromodulators are an important treatment for facial synkinesis. Whether a difference in efficacy exists among the 3 different botulinum neuromodulators used in treating this condition remains unknown. Objective: To evaluate the effectiveness of 3 commercially available botulinum toxin neuromodulators in the treatment of facial synkinesis. Design, Setting, and Participants: In this single-blind, 3-arm comparison randomized clinical trial, 28 patients at the Facial Nerve Center, University of Utah, Salt Lake City, were randomized to onabotulinumtoxinA, abobotulinumtoxinA, or incobotulinumtoxinA treatment...
September 28, 2017: JAMA Facial Plastic Surgery
Takahiro Azuma, Katsuhiko Nakamura, Mika Takahashi, Hitomi Miyoshi, Naoki Toda, Hidetaka Iwasaki, Noriaki Takeda
OBJECTIVE: We investigated whether the value of ENoG is a predictive factor for the development of facial synkinesis in patients with facial palsy. METHODS: The degree of oral-ocular synkinesis was evaluated quantitatively by an asymmetry of the interpalpebral space width during the mouth movement (% eye opening). Twenty healthy volunteers without a history of facial palsy (12 men and 8 women; 25-65 years old; mean age: 42.3±9.7years) were included in the study to examine the normal range of % eye opening...
September 28, 2017: Auris, Nasus, Larynx
Renzo Manara, Federica Di Nardo, Alessandro Salvalaggio, Antonio Agostino Sinisi, Guglielmo Bonanni, Vincenzo Palumbo, Elena Cantone, Arturo Brunetti, Francesco Di Salle, Arianna D'errico, Andrea Elefante, Fabrizio Esposito
Mirror movements (MM) might be observed in congenital and acquired neurodegenerative conditions but their anatomic-functional underpinnings are still largely elusive. This study investigated the spectral changes of resting-state functional connectivity in Kallmann Syndrome (hypogonadotropic hypogonadism with hypo/anosmia with or without congenital MM) searching for insights into the phenomenon of MM. Forty-four Kallmann syndrome patients (21 with MM) and 24 healthy control subjects underwent task (finger tapping) and resting-state functional MRI...
January 2018: Human Brain Mapping
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