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https://www.readbyqxmd.com/read/28550623/malignant-tumors-associated-with-juvenile-polyposis-syndrome-in-japan
#1
REVIEW
Hideyuki Ishida, Keiichiro Ishibashi, Takeo Iwama
PURPOSE: The risk of malignant tumors developing in association with juvenile polyposis syndrome (JPS) was evaluated to explore the optimal treatment for this rare disease. METHODS: We reviewed the data on JPS cases reported in Japan between January, 1971 and March, 2016. RESULTS: A total of 171 cases were evaluable. Of these 171 patients, 83 (48.5%) were female and the median age at diagnosis was 28 years (range 1-80 years). The polyps were located in the stomach alone (n = 62; 36...
May 26, 2017: Surgery Today
https://www.readbyqxmd.com/read/28550512/duplex-ultrasound-versus-clinical-surveillance-in-the-prediction-of-tips-malfunction-placed-for-refractory-ascites-is-ultrasound-surveillance-useful
#2
Shamar Young, Patrick Scanlon, Prashant Sherestha, Jafar Golzarian, Tina Sanghvi
PURPOSE: Since the advent of expanded polytetrafluoroethylene-covered stents and the improved patency they confer for transjugular intrahepatic portosystemic shunt (TIPS), the need to perform ultrasound surveillance has been debated. Prior reports have failed to separately evaluate patients who had TIPS placed for refractory ascites and variceal bleeding. The difference in morbidity from TIPS malfunction between these cohorts argues for distinction between the two. This retrospective review aims to determine whether Duplex ultrasound or return of symptoms more accurately predicts TIPS dysfunction...
May 26, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28550496/prostate-cancer-in-jordanian-arab-population-erg-status-and-relationship-with-clinicopathologic-characteristics
#3
Najla Aldaoud, Nour Abdo, Samir Al Bashir, Mohammad Alqudah, Noor Marji, Hiba Alzou'bi, Rami Alazab, Kiril Trpkov
TMPRSS2/ERG fusion was found to be the most common genetic event in prostate adenocarcinoma. There is a strong correlation between the fusion and ERG-positive immunostaining. Many studies showed racial variation in ERG expression in prostate cancer patients. There is no data however on the rate of ERG-positive cancer in Jordanian or Arab population. We evaluated the frequency and the significance of ERG fusion in Jordanian-Arab population using immunohistochemistry for ERG. The cohort included 193 prostate cancer specimens: 109 needle core biopsies, 45 radical prostatectomies, 37 transurethral resections of prostate, and 2 enucleation specimens...
May 26, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28550473/the-significance-of-de-ritis-aspartate-transaminase-alanine-transaminase-ratio-in-predicting-pathological-outcomes-and-prognosis-in-localized-prostate-cancer-patients
#4
Huitao Wang, Kewei Fang, Jinsong Zhang, Yongming Jiang, Guang Wang, Haiyan Zhang, Tao Chen, Xin Shi, Yuhang Li, Fei Duan, Jianhe Liu
PURPOSE: To illustrate whether De Ritis (aspartate transaminase-AST/alanine transaminase-ALT) ratio is useful in risk stratification of localized prostate cancer and propose an easy predictive model for biochemical recurrence-free survival (BCRFS). METHODS: In total, 438 patients who underwent radical prostatectomy were included in this study. Blood samples including AST and ALT were collected 1-7 days before surgery. An elevated AST and ALT value was defined as over 40 or 56 IU/L...
May 26, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28550393/interval-magnetic-resonance-imaging-an-alternative-to-guidelines-for-indeterminate-nodules-discovered-in-the-cirrhotic-liver
#5
Eliza W Beal, Joseph F Kearney, Jeffery M Chakedis, A James Hanje, Lanla F Conteh, Sylvester M Black, Kenneth Washburn, Kristin M Dittmar, Timothy M Pawlik, Mary R Dillhoff, Carl R Schmidt
BACKGROUND: Current guidelines for the management of indeterminate nodules discovered on surveillance imaging recommend alternate imaging modality or biopsy. This study evaluates the use of short interval MRI rather than immediate CT or biopsy. METHOD: This retrospective cohort study examines outcomes of 111 patients with indeterminate nodules reviewed by a single institution's Liver Tumor Board 2011-2016. Analysis was focused on outcomes stratified by management decision...
May 26, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28550385/metastatic-breast-carcinoma-to-the-superior-oblique-in-a-male
#6
Yao Wang, Pradeep Mettu, Amanda Maltry, Andrew Harrison, Ali Mokhtarzadeh
We describe a case of breast cancer metastatic to the superior oblique, in a male. The patient was a 66-year-old Caucasian male with a history of stage IIIB rectal adenocarcinoma and stage IIA left breast carcinoma diagnosed 12 years and 5 years prior, respectively, who presented with headaches and intermittent diplopia. He underwent left total mastectomy with sentinel lymph node biopsy 6 years prior, which showed ER/PR+, HER2/neu-, moderately-differentiated, infiltrating ductal carcinoma with 3/14 positive nodes...
May 26, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28550058/whole-genome-and-core-genome-multilocus-sequence-typing-and-single-nucleotide-polymorphism-analyses-of-listeria-monocytogenes-associated-with-an-outbreak-linked-to-cheese-united-states-2013
#7
Yi Chen, Yan Luo, Heather Carleton, Ruth Timme, David Melka, Tim Muruvanda, Charles Wang, George Kastanis, Lee S Katz, Lauren Turner, Angela Fritzinger, Terence Moore, Robert Stones, Joseph Blankenship, Monique Salter, Mickey Parish, Thomas S Hammack, Peter S Evans, Cheryl L Tarr, Marc W Allard, Errol A Strain, Eric W Brown
Epidemiological findings of a listeriosis outbreak in 2013 implicated Hispanic-style cheese produced by Company A, and pulsed-field gel electrophoresis (PFGE) and whole genome sequencing (WGS) were performed on clinical isolates and representative isolates collected from Company A cheese and environmental samples during the investigation. The results strengthened the evidence for cheese as the vehicle. Surveillance sampling and WGS three months later revealed that the equipment purchased by Company B from Company A yielded an environmental isolate highly similar to all outbreak isolates...
May 26, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28549961/preliminary-results-of-aorfix-tm-stent-graft-to-treat-infrarenal-abdominal-aortic-aneurysms-with-severe-proximal-aortic-neck-angulation
#8
Pietro Volpe, Mafalda Massara, Antonino Alberti, Santo Marino, Alberto Volpe, Daniela Mazzaccaro, Silvia Stegher, Giovanni Nano
BACKGROUND: We report a preliminary experience about endovascular aortic repair (EVAR) of infrarenal abdominal aneurysm (iAAA) with severe proximal aortic neck angulation using the Aorfix(TM) stent graft. METHODS: Data of consecutive patients with iAAA with severe proximal neck angulation submitted to endovascular repair between September 2012 and December 2014 in two Italian centres of Vascular and Endovascular Surgery were retrospectively reviewed and outcomes analyzed using the software JMP 5...
May 23, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28549939/scientific-consultation-on-the-safety-and-containment-of-new-poliovirus-strains-for-vaccine-production-clinical-regulatory-testing-and-research-report-of-a-meeting-held-at-nibsc-potters-bar-hertfordshire-uk-6-7th-july-2016
#9
Philip D Minor, Blanche Lane, South Mimms, Potters Bar
When poliomyelitis is totally eradicated from the natural world containment will be vital to prevent its re-emergence. The matter has become pressing as type 2 component of oral polio vaccine was completely withdrawn by May 2016 as wild ty[e 2 was declared eradicated. Work on polioviruses must be contained in accordance with GAPIII (the third version of the Global Action Plan of WHO). Some activities will be essential for years after eradication. Vaccine production and control, surveillance and supportive applied and academic research must all continue...
May 23, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28549882/trends-in-the-use-of-laboratory-tests-for-the-diagnosis-of-clostridium-difficile-infection-and-association-with-incidence-rates-in-quebec-canada-2010-2014
#10
C Bogaty, S Lévesque, C Garenc, C Frenette, D Bolduc, L-A Galarneau, C Lalancette, V Loo, C Tremblay, M Trudeau, J Vachon, M Dionne, J Villeneuve, J Longtin, Y Longtin
BACKGROUND: Several Clostridium difficile infection (CDI) surveillance programs do not specify laboratory strategies to use. We investigated the evolution in testing strategies used across Quebec, Canada, and its association with incidence rates. METHODS: Cross-sectional study of 95 hospitals by surveys conducted in 2010 and in 2013-2014. The association between testing strategies and institutional CDI incidence rates was analyzed via multivariate Poisson regressions...
May 23, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28549877/heat-map-for-data-visualization-in-infection-control-epidemiology-an-application-describing-the-relationship-between-hospital-acquired-infections-simplified-acute-physiological-score-ii-and-length-of-stay-in-adult-intensive-care-units
#11
Robin Ohannessian, Thomas Bénet, Laurent Argaud, Claude Guérin, Céline Guichon, Vincent Piriou, Thomas Rimmelé, Raphaele Girard, Solweig Gerbier-Colomban, Philippe Vanhems
BACKGROUND: Hospital-acquired infections (HAIs) in intensive care units (ICUs) are associated with increased length of stay (LOS). The objective of this study was to graphically describe by heat mapping LOS of patients hospitalized in ICUs related to the occurrence of HAI and severity at admission measured by the Simplified Acute Physiological Score II (SAPSII). METHODS: Adult patients hospitalized in ICUs of Lyon University Hospitals (France) were included in an active standardized surveillance study of HAI from January 1, 1995-December 31, 2012...
May 23, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28549857/low-seroprevalence-of-zika-virus-in-cameroonian-blood-donors
#12
Bouba Gake, Marie A Vernet, Isabelle Leparc-Goffart, Jan Felix Drexler, Ernest A Gould, Pierre Gallian, Xavier de Lamballerie
A Zika virus seroepidemiology study was performed in 1084 blood donors collected from August to October 2015 in six sites of Cameroon representing a large panel of eco-environments. Samples were tested using an anti-NS1 IgG ELISA detection kit and positives were further confirmed by seroneutralization. The observed global seroprevalence was low (around 5%, peaking at 10% and 7.7% in Douala and Bertoua, respectively) with risk factors associated with seropositivity pointing to the existence of a local (peri-)sylvatic cycle of transmission...
May 23, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28549821/effect-of-median-household-income-on-surgical-approach-and-survival-in-renal-cell-carcinoma
#13
Jacob Katsnelson, Rebecca J Barnes, Hunaiz A Patel, Daphne Monie, Theodor Kaufman, Nicholas J Hellenthal
PURPOSE: We sought to determine whether median household income (MHI) independently predicts surgical approach (partial vs. radical nephrectomy) and survival in patients with renal cell carcinoma. METHODS: The U.S. Surveillance Epidemiology and End Results Database (1988-2011) was queried to examine kidney cancer cases and linked to the Area Health Resources File. We correlated surgical approach and survival, both overall and cancer-specific, with tumor stage, age, race, sex, and income data...
May 23, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28549732/metachronous-colon-polyps-in-younger-versus-older-adults-a-case-control-study
#14
Sajan Jiv Singh Nagpal, Dhruvika Mukhija, Madhusudhan Sanaka, Rocio Lopez, Carol A Burke
BACKGROUND AND AIMS: The incidence of colorectal cancer (CRC) in the United States has decreased substantially in individuals aged 50 and older. Contrariwise, it is increasing in young adults. The polyp characteristics on baseline and follow-up colonoscopy in young adults are not well characterized. We describe the polyp characteristics on baseline and follow-up colonoscopy in adults < 40 years and determined factors associated with the occurrence of metachronous, advanced neoplasia or high risk (HR) polyp features...
May 23, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28549714/the-enigmatic-role-of-viruses-in-multiple-sclerosis-molecular-mimicry-or-disturbed-immune-surveillance
#15
REVIEW
Jens Geginat, Moira Paroni, Massimiliano Pagani, Daniela Galimberti, Raffaele De Francesco, Elio Scarpini, Sergio Abrignani
Multiple sclerosis (MS) is a T cell driven autoimmune disease of the central nervous system (CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote MS remains unclear. However, there is increasing evidence that the CNS is continuously surveyed by virus-specific T cells, which protect against reactivating neurotropic viruses. Here, we discuss how viral infections could lead to the breakdown of self-tolerance in genetically predisposed individuals, and how the reactivations of viruses in the CNS could induce the recruitment of both autoaggressive and virus-specific T cell subsets, causing relapses and progressive disability...
May 23, 2017: Trends in Immunology
https://www.readbyqxmd.com/read/28549606/variable-performance-of-four-commercial-chromogenic-media-for-detection-of-methicillin-resistant-staphylococcus-aureus-isolates-harbouring-mecc
#16
Céline Dupieux, Camille Kolenda, Anders Rhod Larsen, Bruno Pichon, Mark Holmes, Michèle Bes, Christopher Teale, Elizabeth Dickson, Robert Hill, Robert Skov, Angela Kearns, Frédéric Laurent
In this study, the performances of four methicillin-resistant Staphylococcus aureus (MRSA) chromogenic screening media were compared for detecting mecC-positive MRSA. Using 111 clinical isolates representative of the various mecC-MRSA clones in Europe, chromID(®) MRSA (bioMérieux) and Brilliance(TM) MRSA 2 (Oxoid Ltd.) showed higher sensitivity (99.1% and 97.3%, respectively) than BBL(TM) CHROMagar(®) MRSA II (BD Diagnostics) and MRSASelect(TM) (Bio-Rad) (79.3% and 63.1%, respectively) (P < 0.0001). These findings have important implications for effective public health diagnostics and epidemiological surveillance of MRSA...
May 23, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28549522/pathobiology-of-human-papillomaviruses-in-human-immunodeficiency-virus-infected-persons
#17
REVIEW
Uma Krishnamurti, Elizabeth R Unger
There is a complex interrelationship between human papillomaviruses (HPV) and human immunodeficiency viruses (HIV) that has been recognized from the start of the HIV epidemic. Cervical cancer was used as a surveillance indicator for acquired immunodeficiency syndrome (AIDS) before definitive identification of the viral etiology of either condition were known. Careful epidemiologic studies combined with clinical and laboratory measures of HPV, HPV-associated disease, and HIV have helped us understand many aspects of the relationship between these two virus groups; however, questions remain...
April 6, 2017: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/28549514/validation-of-surgical-site-infection-surveillance-data-in-colon-procedures-reported-to-the-connecticut-department-of-public-health
#18
Lauren A Backman, Evelyn Carusillo, Laurie N D'aquila, Richard Melchreit, Renee Fekieta
A validation study of 692 patients undergoing colon surgery during the fourth quarter of 2012 identified 102 surgical site infections, of which 34% were not reported to the National Healthcare Safety Network. Possible reasons for underreporting included the misinterpretation of the National Healthcare Safety Network surgical site infection definition and variations in case-finding methods. Colon procedure denominator data were also reviewed to determine inaccuracies. Error rates were highest for implant presence (34%), endoscope use (32%), and procedure duration (33%)...
June 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28549513/assessment-of-the-accuracy-and-consistency-in-the-application-of-standardized-surveillance-definitions-a-summary-of-the-american-journal-of-infection-control-and-national-healthcare-safety-network-case-studies-2010-2016
#19
Marc-Oliver Wright, Katherine Allen-Bridson, Joan N Hebden
BACKGROUND: The Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) surveillance definitions are the most widely used criteria for health care-associated infection (HAI) surveillance. NHSN participants agree to conduct surveillance in accordance with the NHSN protocol and criteria. To assess the application of these standardized surveillance specifications and offer infection preventionists (IPs) opportunities for ongoing education, a series of case studies, with questions related to NHSN definitions and criteria were published...
June 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28549512/infection-prevention-workforce-potential-benefits-to-educational-diversity
#20
Sara M Reese, Heather M Gilmartin
BACKGROUND: Nurses have historically occupied the infection preventionist (IP) role. As the knowledge and skills needed to advance the field expand, professionals from public health and the laboratory sciences have become IPs. Our study describes the characteristics of current IPs and assesses for relationships between background, certification, experience, and type of work performed. METHODS: The data were drawn from an existing dataset collected in the conduct of the Association for Professionals in Infection Control and Epidemiology (APIC) MegaSurvey...
June 1, 2017: American Journal of Infection Control
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