keyword
MENU ▼
Read by QxMD icon Read
search

Cluster headache

keyword
https://www.readbyqxmd.com/read/28677993/the-pathophysiology-of-episodic-cluster-headache-insights-from-recent-neuroimaging-research
#1
Fu-Chi Yang, Kun-Hsien Chou, Chen-Yuan Kuo, Yung-Yang Lin, Ching-Po Lin, Shuu-Jiun Wang
Background Cluster headache is a disorder characterized by intermittent, severe unilateral head pain accompanied by cranial autonomic symptoms. Most cases of CH are episodic, manifesting as "in-bout" periods of frequent headache separated by month-to-year-long "out-of-bout" periods of remission. Previous imaging studies have implicated the hypothalamus and pain matrix in the pathogenesis of episodic CH. However, the pathophysiology driving the transition between in- and out-of-bout periods remains unclear. Methods The present study provides a narrative review of previous neuroimaging studies on the pathophysiology of episodic CH, addressing alterations in brain structures, metabolism, and structural and functional connectivity occurring between bout periods...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28670718/ketamine-infusion-combined-with-magnesium-as-a-therapy-for-intractable-chronic-cluster-headache-report-of-two-cases
#2
Xavier Moisset, Pierre Clavelou, Michel Lauxerois, Radhouane Dallel, Pascale Picard
BACKGROUND: Chronic cluster headache (CH) is a rare, highly disabling primary headache condition. As NMDA receptors are possibly overactive in CH, NMDA receptor antagonists, such as ketamine, could be of interest in patients with intractable CH. CASE REPORTS: Two Caucasian males, 28 and 45 years-old, with chronic intractable CH, received a single ketamine infusion (0.5 mg/kg over 2 h) combined with magnesium sulfate (3000 mg over 30 min) in an outpatient setting...
July 3, 2017: Headache
https://www.readbyqxmd.com/read/28648089/evidence-of-activation-of-vagal-afferents-by-non-invasive-vagus-nerve-stimulation-an-electrophysiological-study-in-healthy-volunteers
#3
Romain Nonis, Kevin D'Ostilio, Jean Schoenen, Delphine Magis
Background Benefits of cervical non-invasive vagus nerve stimulation (nVNS) devices have been shown in episodic cluster headache and preliminarily suggested in migraine, but direct evidence of vagus nerve activation using such devices is lacking. Vagal somatosensory evoked potentials (vSEPs) associated with vagal afferent activation have been reported for invasive vagus nerve stimulation (iVNS) and non-invasive auricular vagal stimulation. Here, we aimed to show and characterise vSEPs for cervical nVNS. Methods vSEPs were recorded for 12 healthy volunteers who received nVNS over the cervical vagus nerve, bipolar electrode/DS7A stimulation over the inner tragus, and nVNS over the sternocleidomastoid (SCM) muscle...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28644963/self-report-and-subjective-history-in-the-diagnosis-of-painful-neck-conditions-a-systematic-review-of-diagnostic-accuracy-studies
#4
REVIEW
Adam Mizer, Alexa Bachmann, Jessie Gibson, Megan Burrowbridge Donaldson
Rising healthcare costs and inherent risks with over-utilizing diagnostic imaging require a quality subjective examination to improve effectiveness and time management of physical examinations. This systematic review investigates the diagnostic accuracy of subjective history and self-report items to determine if there is significant alteration in the probability of identifying specific painful neck conditions. Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. INCLUSION CRITERIA: 1) Written in the English language 2) Cervical pain with/without referred upper extremity or head pain 3) Subjective history or self-report items 4) Study designs that reported diagnostic statistics or allowed calculation of sensitivities, specificities, diagnostic odds ratios, and likelihood ratios 5) used a reference standard that has a sensitivity or specificity ≥75% or a diagnostic tool that is strongly supported in the literature where this data is not available...
June 8, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28644256/cluster-like-headache-secondary-to-focal-cervical-myelitis
#5
Dong-Eun Kim, Ji-Yun Park, Hyeonuk Ha, Geum-Jin Yoon, Bang-Hoon Cho, Seung-Han Lee
BACKGROUND: Cluster headache (CH) is characterized by attacks of severe periorbital pain associated with autonomic symptoms. As with other forms of primary headache, structural lesions should be excluded, particularly if the headache presents with an atypical pattern. CASE: We report a 41-year-old woman who had no previous history of primary headache and showed a poor response to medication for CH. The patient was finally diagnosed as secondary headache with CH feature due to focal myelitis at the cervical level of the spinal cord...
July 2017: Neurologist
https://www.readbyqxmd.com/read/28644160/calcitonin-gene-related-peptide-targeted-therapies-for-migraine-and-cluster-headache-a-review
#6
Nathaniel M Schuster, Alan M Rapoport
Calcitonin gene-related peptide (CGRP) is a signaling neuropeptide released from activated trigeminal sensory afferents in headache and facial pain disorders. There are a handful of CGRP-targeted therapies currently in phase 3 studies for migraine acute treatment or prevention. Currently, 4 monoclonal antibodies targeting either the CGRP ligand or receptor are being studied for migraine prevention: ALD403 (eptinezumab), AMG 334 (erenumab), LY2951742 (galcanezumab), and TEV-48125 (fremanezumab). Meanwhile, 1 small-molecule CGRP receptor antagonist (ubrogepant, MK-1602) is currently in phase 3 studies for the acute treatment of migraine...
July 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28641450/musculoskeletal-dysfunction-in-migraine-patients
#7
Kerstin Luedtke, Wiebke Starke, Arne May
Objective The aim of this project was to evaluate the prevalence and pattern of musculoskeletal dysfunctions in migraine patients using a rigorous methodological approach and validating an international consensus cluster of headache assessment tests. Methods A physiotherapist, blinded towards the diagnosis, examined 138 migraine patients (frequent episodic and chronic), recruited at a specialised headache clinic, and 73 age and gender matched healthy controls following a standardised protocol. Eleven tests, previously identified in an international consensus procedure, were used to evaluate cervical and thoracic musculoskeletal dysfunctions...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28640138/an-unusual-presentation-of-multiple-myeloma-with-unilateral-sudden-vision-loss-a-case-report
#8
Pei-Wen Wu, Ta-Jen Lee, Jim-Ray Chen, Chien-Chia Huang
RATIONALE: Plasma cell neoplasms are categorized by neoplastic proliferation of a single clone of plasma cells which produce a monoclonal immunoglobulin. Plasma cell neoplasms can present as a solitary plasmacytoma or as multiple myeloma. Both of them can progress to multiple myeloma. Once a diagnosis of plasmacytoma has been made, thorough examinations should be carried out for identifying the disease entity. PATIENT CONCERNS AND DIAGNOSES: Herein, we describe an extraordinary rare case of multiple myeloma with initial presentation of a left sphenoid neoplasm resulting in left-sided headache and rapid deterioration of visual acuity...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28616776/evidence-towards-rna-binding-motif-rnp1-rrm-protein-3-rbm3-as-a-potential-biomarker-of-lithium-response-in-bipolar-disorder-patients
#9
Eleni Merkouri Papadima, Paola Niola, Carla Melis, Claudia Pisanu, Donatella Congiu, Cristiana Cruceanu, Juan Pablo Lopez, Gustavo Turecki, Raffaella Ardau, Giovanni Severino, Caterina Chillotti, Maria Del Zompo, Alessio Squassina
Lithium has been used for more than six decades for the management of bipolar disorder (BD). In a previous transcriptomic study, we showed that patients affected by either BD or cluster headache, both disorders characterized by circadian disturbances and response to lithium in a subgroup of patients, have higher expression of the RNA binding motif (RNP1, RRM) protein 3 (RBM3) gene compared to controls. To investigate whether RBM3 could represent a biomarker of lithium response, we screened raw microarray expression data from lymphoblastoid cell lines (LCLs) derived from 20 BD patients, responders or non-responders to lithium...
June 14, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28589641/the-yield-of-head-computed-tomography-in-patients-with-new-onset-of-transient-headaches
#10
Niamh Hammond, Annemarei Ranta
BACKGROUND: Headache is a common patient complaint. The threshold for brain imaging in headache is debated, especially when the headache is transient, although even if the headache has resolved at presentation a sentinel bleed heralding a subarachnoid haemorrhage (SAH) often remains a concern. AIMS: To assess the yield of computed tomography (CT) head scan referrals for patients with transient headache symptoms. METHODS: This study looked at six months of CT results assessing for brain pathology with a particular focus on subarachnoid haemorrhage...
June 7, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28583000/suicide-in-primary-headaches-in-48-countries-a-physician-survey-based-study
#11
Jose Maria Trejo-Gabriel-Galan, Irene Aicua-Rapún, Esther Cubo-Delgado, Carmen Velasco-Bernal
Aim To investigate the relationship between primary headache types and accomplished or attempted suicide in countries from all world regions. Methods Data were obtained using a questionnaire about suicide due to headache in a face-to-face interview with 203 physicians with expertise in headaches. They came from 48 countries, and from all continents. Results Primary headaches cause one suicide per 1,000,000 population each year (1% of the suicide rate due to all causes). Cluster headache and migraines account for 70-80% of them...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28581025/clinical-characteristics-and-treatment-patterns-among-patients-diagnosed-with-cluster-headache-in-u-s-healthcare-claims-data
#12
Casey K Choong, Janet H Ford, Allen W Nyhuis, Shivang G Joshi, Rebecca L Robinson, Sheena K Aurora, James M Martinez
OBJECTIVE: To characterize demographics, clinical characteristics, and treatment patterns of patients with cluster headache (CH). BACKGROUND: CH is an uncommon trigeminal autonomic cephalalgia with limited evidence-based treatment options. Patients suffer from extremely painful unilateral headache attacks and autonomic symptoms with episodic and chronic cycles. DESIGN/METHODS: This retrospective analysis used insurance claims from Truven Health Analytics MarketScan(®) research databases from 2009 to 2014...
June 5, 2017: Headache
https://www.readbyqxmd.com/read/28578604/does-palliative-chemotherapy-provide-a-palliative-effect-on-symptoms-in-late-palliative-stages-an-interview-study-with-oncologists
#13
Peter Strang, Jenny Bergqvist
BACKGROUND: The possible chemotherapy effects on symptoms in late stages of palliative chemotherapy are seldom registered in clinical practice or investigated as primary outcomes. The aim was therefore to study physicians' opinions and experiences about chemotherapy effects on symptoms. MATERIAL AND METHODS: Thirty-five physicians (mainly oncologists) with variation as regards age, gender and experience were included in a qualitative study with semi-structured interviews...
June 3, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28549263/prevalence-reasons-perceived-effects-and-correlates-of-medical-marijuana-use-a-review
#14
REVIEW
Ji-Yeun Park, Li-Tzy Wu
BACKGROUND: The use of marijuana for medical purposes is now legal in some U.S. states and other jurisdictions, such as Canada, and Israel. Despite the widespread legalization of medical marijuana globally, there is limited information on patterns and correlates of medical marijuana use (MMU). We conducted a literature review to assess prevalence, reasons, perceived effects, and correlates of MMU among adolescents and adults. METHODS: We searched peer-reviewed articles in English between January 1996 and August 2016 from several databases (PubMed, Google Scholar, Embase, CINAHL, and PsycINFO) using different combinations of keywords...
May 16, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28547735/the-burden-of-headache-disorders-in-ethiopia-national-estimates-from-a-population-based-door-to-door-survey
#15
Mehila Zebenigus, Redda Tekle-Haimanot, Dawit K Worku, Hallie Thomas, Timothy J Steiner
BACKGROUND: Headache disorders are the third-highest cause of disability worldwide, with migraine and medication-overuse headache (MOH) the major contributors. In Ethiopia we have shown these disorders to be highly prevalent: migraine 17.7%, TTH 20.6%, probable MOH (pMOH) 0.7%, any headache yesterday (HY) 6.4%. To inform local health policy, we now estimate disability and other burdens attributable to headache in this country. METHODS: In a cross-sectional survey using cluster-randomized sampling, we visited households unannounced in four diverse regions (urban and rural) of Ethiopia...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28544265/lasting-improvement-of-medication-overuse-headache-after-brief-intervention-a-long-term-follow-up-in-primary-care
#16
E S Kristoffersen, J Straand, M B Russell, C Lundqvist
BACKGROUND AND PURPOSE: Withdrawal therapy improves the headache situation for many patients with medication-overuse headache (MOH), but relapses are common. The objective was to assess the long-term effectiveness of a general practitioner conducted brief intervention (BI) for MOH. METHODS: Sixty MOH patients initially participating in a blinded cluster-randomized controlled trial evaluating BI versus business as usual (BAU) were followed up for 16 months. Follow-up was open after 6 months...
May 23, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28542727/tics-in-tacs-a-step-into-an-avalanche-systematic-literature-review-and-conclusions
#17
Christian Wöber
BACKGROUND: Trigeminal autonomic cephalalgias (TACs) comprise cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache attacks, and hemicrania continua. In some cases, trigeminal neuralgia (TN, "tic douloureux") or TN-like pain may co-occur with TACs. AIM: This article will review the co-occurrence and overlap of TACs and tics in order to contribute to a better understanding of the issue and an improved management of the patients. METHODS: For performing a systematic literature review Pubmed was searched using a total of ten terms...
May 19, 2017: Headache
https://www.readbyqxmd.com/read/28540017/cluster-headache-associated-with-secondary-unilateral-blepharospasm-a-case-report-and-review-of-the-literature
#18
Abbas Bagheri, Minoo Mohammadi, Ghader Harooni, Keyvan Khosravifard, Mohadeseh Feizi, Shahin Yazdani
PURPOSE: Cluster headache is one of the most serious types of headache that is accompanied by autonomic parasympathetic symptoms. Its association with hemifacial spasm in the same side had been rarely reported. The aim of this report is describing a case with this association and treatment strategies. CASE REPORT: Here we report a 37-year-old female with cluster headache associated with secondary unilateral blepharospasm that was successfully treated with combination therapy including botulinum toxin injection...
April 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28539654/quasispecies-composition-and-evolution-of-a-typical-zika-virus-clinical-isolate-from-suriname
#19
Sander van Boheemen, Ali Tas, S Yahya Anvar, Rebecca van Grootveld, Irina C Albulescu, Martijn P Bauer, Mariet C Feltkamp, Peter J Bredenbeek, Martijn J van Hemert
The arthropod-borne Zika virus (ZIKV) is currently causing a major international public health threat in the Americas. This study describes the isolation of ZIKV from the plasma of a 29-year-old female traveler that developed typical symptoms, like rash, fever and headache upon return from Suriname. The complete genome sequence including the 5' and 3' untranslated regions was determined and phylogenetic analysis showed the isolate clustering within the Asian lineage, close to other viruses that have recently been isolated in the Americas...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28527063/the-role-of-anti-cgrp-antibodies-in-the-pathophysiology-of-primary-headaches
#20
Piero Barbanti, Cinzia Aurilia, Luisa Fofi, Gabriella Egeo, Patrizia Ferroni
Calcitonin gene-related peptide (CGRP), a potent vasodilator and pain-signaling neuropeptide, is a validated therapeutic target for migraine and cluster headache. Four anti-CGRP monoclonal antibodies (mAbs) have been developed, representing the first specific, mechanism-based, migraine prophylactic treatment. CGRP mAbs demonstrated good efficacy coupled to excellent tolerability and safety in 5 phase II clinical trials. Notably, CGRP mAbs induced complete migraine remission in a patients' subset. To date, more than 20 phase III trials using CGRP mAbs for of episodic and chronic migraine and cluster headache prevention are ongoing...
May 2017: Neurological Sciences
keyword
keyword
7957
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"