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https://www.readbyqxmd.com/read/28329903/-headache-treatment
#1
Hans Christoph Diener, Dagny Holle-Lee, Steffen Nägel, Charly Gaul
A precondition for the successful treatment of headaches is the correct headache diagnosis. Triptans are effective for attack treatment of migraine and cluster headache. However, there are not effective for the treatment of tension-type headache. For the prevention of frequent episodic migraine betablockers, flunarizine, topiramate and amitriptyline are recommended. For the prevention of chronic migraine evidence is only available for onabotulinumtoxinA and topiramate. For prophylactic treatment of tension-type headaches tricyclic antidepressants are used...
March 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28329901/-pathophysiology-of-headaches
#2
Charly Gaul, Karl Meßlinger, Dagny Holle-Lee, Lars Neeb
Pathophysiological concepts of primary headache diseases have been developed significantly in the last decades. Nevertheless pathophysiology of single diseases is unexplained. Migraine headache arises from activation and sensibilization of trigeminal nociceptors, essential processes are located at the meninges and the meningeal vessels. Calcitonin gene-related peptide (CGRP) seems to have essential importance concerning migraine and cluster headache. Mechanisms leading to peripheral and central sensitization are relevant in chronification of migraine and tension-type headache...
March 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28320419/cerebellar-ependymoma-with-overlapping-features-of-clear-cell-and-tanycytic-variants-mimicking-hemangioblastoma-a-case-report-and-literature-review
#3
Xiu-Peng Zhang, Yang Liu, Di Zhang, Qin Zheng, Chen Wang, Liang Wang, Qing-Chang Li, Xue-Shan Qiu, En-Hua Wang
BACKGROUND: Imaging and histology of clear-cell ependymoma and cerebellum-based hemangioblastoma are similar; distinguishing between them is a diagnostic challenge. CASE PRESENTATION: A 62-year-old Chinese woman presented with an intermittent headache of 8 years' duration. Computed tomography and magnetic resonance imaging revealed a mass in the cerebellum. Neurological imaging suggested hemangioblastoma (HB). Histologically, the tumor included cellular and paucicellular areas, in which cells were arranged in nests or diffusely distributed; and a highly vascular area, in which tumor cells were arranged in clusters and separated by capillaries...
March 20, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28295636/t-cell-lymphoblastic-lymphoma-leukemia-within-an-adrenocorticotropic-hormone-and-thyroid-stimulating-hormone-positive-pituitary-adenoma-a-cytohistological-correlation-emphasizing-importance-of-intra-operative-squash-smear
#4
Rakesh K Gupta, Ravindra K Saran, Arvind K Srivastava, Anita Jagetia, Lalit Garg, Mehar C Sharma
We present a rare case of primary pituitary T cell lymphoma/leukemia (T-LBL) in association with adrenocorticotropic hormone (ACTH) and thyroid stimulating hormone (TSH) expressing pituitary adenoma in a 55-year-old woman highlighting the importance of intra-operative squash smears examination. The patient presented with complaints of headache, diminution of vision and recent onset altered sensorium. MRI revealed a mass lesion in the sellar-suprasellar region with non-visualization of pituitary gland separately, extending to involve adjacent structures diagnosed as invasive pituitary macroadenoma...
March 13, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28295284/diffuse-large-b-cell-lymphoma-of-the-nasopharynx-presenting-with-cluster-like-headache
#5
Adrian Budhram, Andrew Leung, Nikhil Sangle, Alexander V Khaw
No abstract text is available yet for this article.
March 13, 2017: Headache
https://www.readbyqxmd.com/read/28286178/vagus-nerve-stimulation-suppresses-acute-noxious-activation-of-trigeminocervical-neurons-in-animal-models-of-primary-headache
#6
Simon Akerman, Bruce Simon, Marcela Romero-Reyes
Vagus nerve stimulation (VNS) has been reported to be effective in the abortive treatment of both migraine and cluster headache. Using validated animal models of acute dural-intracranial (migraine-like) and trigeminal-autonomic (cluster-like) head pain we tested whether VNS suppresses ongoing and nociceptive-evoked firing of trigeminocervical neurons to explain its abortive effects in migraine and cluster headache. Unilateral VNS was applied invasively via hook electrodes placed on the vagus nerve. A single dose of ipsilateral or contralateral VNS, to trigeminal recording and dural-stimulating side, suppressed ongoing spontaneous and noxious dural-evoked trigeminocervical neuronal firing...
March 9, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28276744/the-cohen-hoberman-inventory-of-physical-symptoms-factor-structure-and-preliminary-tests-of-reliability-and-validity-in-the-general-population
#7
Sarah F Allen, Mark A Wetherell, Michael A Smith
OBJECTIVE: The present study aimed to investigate the factor structure and psychometric properties of the Cohen-Hoberman inventory of physical symptoms (CHIPS). Construct and discriminant validity were examined by assessing associations between factors and subjective health complaints (SHC) inventory subscales in addition to measures of pain sensitivity, perceived stress and psychological distress. DESIGN: A cross-sectional online survey was conducted with 535 healthy individuals from the general population (80...
February 17, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28271496/genetics-of-migraine-insights-into-the-molecular-basis-of-migraine-disorders
#8
REVIEW
Heidi G Sutherland, Lyn R Griffiths
Migraine is a complex, debilitating neurovascular disorder, typically characterized by recurring, incapacitating attacks of severe headache often accompanied by nausea and neurological disturbances. It has a strong genetic basis demonstrated by rare migraine disorders caused by mutations in single genes (monogenic), as well as familial clustering of common migraine which is associated with polymorphisms in many genes (polygenic). Hemiplegic migraine is a dominantly inherited, severe form of migraine with associated motor weakness...
March 8, 2017: Headache
https://www.readbyqxmd.com/read/28271333/non-invasive-neuromodulation-in-primary-headaches
#9
REVIEW
Sarah Miller, Manjit Matharu
PURPOSE OF REVIEW: There is growing interest in neuromodulation for primary headache conditions. Invasive modalities such as occipital nerve stimulation, deep brain stimulation and sphenopalatine ganglion stimulation are reserved for the most severe and intractable patients. Non-invasive options such as vagal nerve stimulation (nVNS), supraorbital nerve stimulation (nSONS) and transcranial magnetic nerve stimulation (TMS) have all emerged as potentially useful headache treatments. This review examines the evidence base for non-invasive neuromodulation in trigeminal autonomic cephalalgias and migraine...
March 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28267062/allodynia-in-cluster-headache
#10
Leopoldine A Wilbrink, Mark A Louter, Onno Pm Teernstra, Erik W van Zwet, Frank Jpm Huygen, Joost Haan, Michel D Ferrari, Gisela M Terwindt
Cutaneous allodynia is an established marker for central sensitization in migraine. There is debate whether cutaneous allodynia may also occur in cluster headache, another episodic headache disorder. Here we examined the presence and severity of allodynia in a large well-defined nation-wide population of people with cluster headache.Using validated questionnaires we assessed, cross-sectionally, ictal allodynia and comorbid depression and migraine in the nation-wide "Leiden University Cluster headache neuro-Analysis" (LUCA) study...
March 4, 2017: Pain
https://www.readbyqxmd.com/read/28209309/cluster-headache-and-macroprolactinoma-case-report-of-a-rare-but-potential-important-causality
#11
Lukas Andereggen, Marie-Luise Mono, Frauke Kellner-Weldon, Emanuel Christ
While headache is not an uncommon symptom in patients suffering from pituitary adenomas, cluster headache (CH) has rarely been reported in such cases. Headache associated with hyperprolactinemia has been reported to be responsive to dopamine agonists (DA agonists) in many patients. We report on a patient with refractory CH secondary to a macroprolactinoma who showed immediate and permanent clinical and radiologic recovery following medical treatment with DA agonists. Measurement of prolactin levels in addition to cranial magnetic resonance imaging might be considered in patients with refractory CH, until the significance of this potential causality becomes clearer...
February 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28202701/chronobiology-differs-between-men-and-women-with-cluster-headache-clinical-phenotype-does-not
#12
Nunu Lund, Mads Barloese, Anja Petersen, Bryan Haddock, Rigmor Jensen
OBJECTIVE: To describe differences between the sexes in the phenotype of cluster headache (CH) in a large, well-characterized clinical CH population. METHODS: Patients from the Danish CH survey aged 18-65 years, diagnosed with CH according to International Classification of Headache Disorders, second edition, completed questionnaires and structured interviews. RESULTS: A total of 351 patients with CH participated, with a male:female ratio of 2:1...
March 14, 2017: Neurology
https://www.readbyqxmd.com/read/28202697/comment-sex-specific-differences-in-cluster-headache-not-a-males-only-disorder
#13
Tim P Jürgens
No abstract text is available yet for this article.
March 14, 2017: Neurology
https://www.readbyqxmd.com/read/28197844/effects-of-non-invasive-vagus-nerve-stimulation-on-attack-frequency-over-time-and-expanded-response-rates-in-patients-with-chronic-cluster-headache-a-post-hoc-analysis-of-the-randomised-controlled-preva-study
#14
Charly Gaul, Delphine Magis, Eric Liebler, Andreas Straube
BACKGROUND: In the PREVention and Acute treatment of chronic cluster headache (PREVA) study, attack frequency reductions from baseline were significantly more pronounced with non-invasive vagus nerve stimulation plus standard of care (nVNS + SoC) than with SoC alone. Given the intensely painful and frequent nature of chronic cluster headache attacks, additional patient-centric outcomes, including the time to and level of therapeutic response, were evaluated in a post hoc analysis of the PREVA study...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28168240/cracked-tooth-syndrome-mimicking-trigeminal-autonomic-cephalalgia-a-report-of-four-cases
#15
Noboru Noma, Kohei Shimizu, Kosuke Watanabe, Andrew Young, Yoshiki Imamura, Junad Khan
BACKGROUND: This report describes four cases of cracked tooth syndrome secondary to traumatic occlusion that mimicked trigeminal autonomic cephalalgias. All patients were referred by general practitioners to the Orofacial Pain Clinic at Nihon University Dental School for assessment of atypical facial pain. CLINICAL PRESENTATION: Case 1: A 51-year-old woman presented with severe pain in the maxillary and mandibular left molars. Case 2: A 47-year-old woman presented with sharp, shooting pain in the maxillary left molars, which radiated to the temple and periorbital region...
February 6, 2017: Quintessence International
https://www.readbyqxmd.com/read/28168134/ocular-inflammatory-disease-as-a-predictor-for-in-hospital-mortality-in-patients-hospitalized-with-disseminated-tuberculosis
#16
Salil Mehta
AIM: To ascertain whether the presence of ocular inflammatory disease is a predictor for death in patients hospitalized with disseminated tuberculosis. METHODS: This is an IRB-approved retrospective study of patients admitted with a diagnosis of disseminated tuberculosis within a seven-year period (2002-2009). The following data was collected from each record: age, sex, details of previous surgeries or therapy, the findings of anterior segment examination, the findings of dilated indirect ophthalmoscopy, systemic findings, investigations done, treatment rendered, and final status (died or discharged)...
January 5, 2017: Curēus
https://www.readbyqxmd.com/read/28152528/post-operative-cluster-headache-following-carotid-endarterectomy
#17
Thijs H T Dirkx, Peter J Koehler
BACKGROUND: Secondary cluster headache following carotid endarterectomy (CEA) is a rare condition and may help us understand the pathophysiology of primary cluster headache. SUMMARY: We describe 2 patients diagnosed with cluster headache, fulfilling the ICHD-IIIB criteria, following CEA. Neither of the patients had headache prior to surgery. They both responded to treatment with oxygen and verapamil. Recent medical literature does not describe any definite cases of cluster headache following CEA...
2017: European Neurology
https://www.readbyqxmd.com/read/28145655/clinical-features-of-cluster-headache-patients-in-korea
#18
Heui Soo Moon, Jeong Wook Park, Kwang Soo Lee, Chin Sang Chung, Byung Kun Kim, Jae Moon Kim, Jong Hee Sohn, Min Kyung Chu, Kyungmi Oh, Soo Jin Cho
Cluster headache (CH) is a rare underdiagnosed primary headache disorder with very severe unilateral pain and autonomic symptoms. Clinical characteristics of Korean patients with CH have not yet been reported. We analyzed the clinical features of CH patients from 11 university hospitals in Korea. Among a total of 200 patients with CH, only 1 patient had chronic CH. The average age of CH patients was 38.1 ± 8.9 years (range 19-60 years) and the average age of onset was 30.7 ± 10.3 years (range 10-57 years)...
March 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28144808/volume-gain-of-periaqueductal-gray-in-medication-overuse-headache
#19
Zhiye Chen, Xiaoyan Chen, Mengqi Liu, Shuangfeng Liu, Lin Ma, Shengyuan Yu
BACKGROUND: Periaqueductal gray (PAG) is a substantial descending pain modulatory center, and previous voxel-based morphometry study confirmed the clusters with increased volume in PAG region in medication-overuse headache (MOH). The aim of this study is to investigate altered PAG volume in MOH using an automated PAG segment method to measure the true PAG volume. METHODS: High resolution three-dimensional T1-weighted fast spoiled gradient recalled echo MR images were obtained from 22 patients with MOH and 22 normal controls (NC)...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28128461/cluster-headache-and-other-tacs-pathophysiology-and-neurostimulation-options
#20
Miguel Ja Láinez, Edelmira Guillamón
BACKGROUND: The trigeminal autonomic cephalalgias (TACs) are highly disabling primary headache disorders. There are several issues that remain unresolved in the understanding of the pathophysiology of the TACs, although activation of the trigeminal-autonomic reflex and ipsilateral hypothalamic activation both play a central role. The discovery of the central role of the hypothalamus led to its use as a therapeutic target. After the good results obtained with hypothalamic stimulation, other peripheral neuromodulation targets were tried in the management of refractory cluster headache (CH) and other TACs...
February 2017: Headache
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