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Pomi-t

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https://www.readbyqxmd.com/read/26898239/phytotherapeutic-interventions-in-the-management-of-biochemically-recurrent-prostate-cancer-a-systematic-review-of-randomised-trials
#1
REVIEW
Margaret Diana van Die, Kerry M Bone, Jon Emery, Scott G Williams, Marie V Pirotta, Channing J Paller
OBJECTIVE: To evaluate the evidence from randomised trials for the efficacy and safety of phytotherapeutic interventions in the management of biochemically recurrent (BCR) prostate cancer, indicated by prostate-specific antigen (PSA) progression, numbers progressing to/time to initiation of androgen-deprivation therapy or salvage therapy. PATIENTS AND METHODS: MEDLINE (Ovid), EMBASE (Ovid), AMED (Ovid), CINAHL (EBSCO) and the Cochrane Library databases were searched...
April 2016: BJU International
https://www.readbyqxmd.com/read/24614693/a-double-blind-placebo-controlled-randomised-trial-evaluating-the-effect-of-a-polyphenol-rich-whole-food-supplement-on-psa-progression-in-men-with-prostate-cancer-the-u-k-ncrn-pomi-t-study
#2
RANDOMIZED CONTROLLED TRIAL
R Thomas, M Williams, H Sharma, A Chaudry, P Bellamy
BACKGROUND: Polyphenol-rich foods such as pomegranate, green tea, broccoli and turmeric have demonstrated anti-neoplastic effects in laboratory models involving angiogenesis, apoptosis and proliferation. Although some have been investigated in small, phase II studies, this combination has never been evaluated within an adequately powered randomised controlled trial. METHODS: In total, 199 men, average age 74 years, with localised prostate cancer, 60% managed with primary active surveillance (AS) or 40% with watchful waiting (WW) following previous interventions, were randomised (2:1) to receive an oral capsule containing a blend of pomegranate, green tea, broccoli and turmeric, or an identical placebo for 6 months...
June 2014: Prostate Cancer and Prostatic Diseases
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