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Hepatitis C in prison

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https://www.readbyqxmd.com/read/28426354/-it-goes-on-everywhere-injection-drug-use-in-canadian-federal-prisons
#1
Emily van der Meulen
BACKGROUND: International and Canadian research on in-prison injection drug use has documented the frequency of its occurrence as well as some of the resulting consequences such as increased prevalence of HIV and hepatitis C virus. Access to prison-based harm reduction programing is thus important. OBJECTIVES: The aim of this study was to learn from former prisoner experiences and insights on in-prison injection drug use in order to advance and improve access to harm reduction options, in particular prison-based needle and syringe programs (PNSPs)...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28404202/hepatitis-c-treatment-as-prevention-evidence-feasibility-and-challenges
#2
REVIEW
Behzad Hajarizadeh, Jason Grebely, Marianne Martinello, Gail V Matthews, Andrew R Lloyd, Gregory J Dore
The advent of interferon-free direct-acting antiviral therapy for hepatitis C virus (HCV) infection has heightened discussion of treatment as prevention. Rapid scale-up in many settings, and the prospect of further treatment simplification have extended therapeutic optimism towards HCV elimination. However, questions remain regarding the feasability of HCV treatment as prevention, including real world efficacy of direct-acting antiviral therapy, particularly among people who inject drugs, and whether expanded treatment access will be sufficient to reduce HCV transmission...
December 2016: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28399843/effectiveness-of-needle-and-syringe-programmes-in-people-who-inject-drugs-an-overview-of-systematic-reviews
#3
Ricardo M Fernandes, Maria Cary, Gonçalo Duarte, Gonçalo Jesus, Joana Alarcão, Carla Torre, Suzete Costa, João Costa, António Vaz Carneiro
BACKGROUND: Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID). Our primary objective was to summarize the evidence on the effectiveness of NSP for PWID in reducing blood-borne infection transmission and injecting risk behaviours (IRB). METHODS: We conducted an overview of systematic reviews that included PWID (excluding prisons and consumption rooms), addressed community-based NSP, and provided estimates of the effect regarding incidence/prevalence of Human Immunodeficiency Virus (HIV), Hepatitis C virus (HCV), Hepatitis B virus (HBV) and bacteremia/sepsis, and/or measures of IRB...
April 11, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28257600/modelling-the-impact-of-incarceration-and-prison-based-hepatitis-c-virus-hcv-treatment-on-hcv-transmission-among-people-who-inject-drugs-in-scotland
#4
Jack Stone, Natasha K Martin, Matthew Hickman, Sharon J Hutchinson, Esther Aspinall, Avril Taylor, Alison Munro, Karen Dunleavy, Erica Peters, Peter Bramley, Peter C Hayes, David J Goldberg, Peter Vickerman
BACKGROUND AND AIMS: People who inject drugs (PWID) experience high incarceration rates, and previous incarceration is associated with elevated hepatitis C virus (HCV) transmission risk. In Scotland, national survey data indicate lower HCV incidence in prison than the community (4.3 versus 7.3 per 100 person-years), but a 2.3-fold elevated transmission risk among recently released (< 6 months) PWID. We evaluated the contribution of incarceration to HCV transmission among PWID and the impact of prison-related prevention interventions, including scaling-up direct-acting antivirals (DAAs) in prison...
March 3, 2017: Addiction
https://www.readbyqxmd.com/read/28256027/ongoing-incident-hepatitis-c-virus-infection-among-people-with-a-history-of-injecting-drug-use-in-an-australian-prison-setting-2005-2014-the-hits-p-study
#5
Evan B Cunningham, Behzad Harjarizadeh, Neil A Bretana, Janaki Amin, Brigid Betz-Stablein, Gregory J Dore, Fabio Luciani, Suzy Teutsch, Kate Dolan, Andrew R Lloyd, Jason Grebely
BACKGROUND: Hepatitis C virus (HCV) transmission is high in prisons. This study investigated trends in HCV incidence and associated factors among a cohort of prisoners with a history of injecting drug use in New South Wales, Australia. METHODS: Data were available from the Hepatitis C Incidence and Transmission Study in prisons (HITS-p) from 2005-2014. Temporal trends in HCV incidence were evaluated. Factors associated with time to HCV seroconversion among people with ongoing injecting was assessed using Cox proportional hazards...
March 3, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/28165441/intravenous-drugs-abuse-as-the-main-risk-factor-of-increasing-hepatitis-c-infection-prevalence-in-prisoners-in-zenica-bosnia-and-herzegovina
#6
Harun Hodžić, Amel Bajramović, Zarema Obradović, Mersiha Mahmić-Kaknjo
Aim To determine the prevalence of hepatitis C virus infection (HCV) among prisoners in Zenica prison, and to investigate the relation between HCV and risky behaviors: intravenous drugs use (IDU), tattooing, promiscuity. Methods This cross-sectional study conducted at the High Security Penitentiary in Zenica involved 200 convicted persons who gave their consents for the research. Their blood was tested by AraGen Hepatitis C Test. Risky behaviors (IDU, tattooing, promiscuity) were tested by an anonymous self-administered questionnaire...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28158850/hepatitis-c-in-a-prison-in-the-north-east-of-england-what-is-the-economic-impact-of-the-universal-offer-of-testing-and-emergent-medications
#7
Joanne Darke, Tricia Cresswell, Stuart McPherson, Abi Hamoodi
No abstract text is available yet for this article.
December 2, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/28094553/burden-of-hiv-syphilis-and-hepatitis-b-and-c-among-inmates-in-a-prison-state-system-in-mexico
#8
Pablo F Belaunzaran-Zamudio, Juan L Mosqueda-Gomez, Alejando Macias-Hernandez, Sonia Rodríguez-Ramírez, Juan Sierra-Madero, Chris Beyrer
We studied the prevalence of HIV, syphilis, hepatitis B virus (HBV), and hepatitis C virus (HCV) infection and associated risk behaviors in the prison state system of Guanajuato, Mexico between September 2011 and February 2012. Blood samples were drawn from adult inmates in all State prisons who agreed to participate in this cross-sectional study. Data on risk behaviors were collected by using self-administered questionnaires. The prevalence of HIV, syphilis, HBV, and HCV infection was 0.6% [95% confidence interval (CI) = 0...
March 6, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28060860/prevalence-and-incidence-of-hcv-infection-among-prisoners-in-central-brazil
#9
Marco Antonio Moreira Puga, Larissa Melo Bandeira, Mauricio Antonio Pompilio, Julio Croda, Grazielli Rocha de Rezende, Luiz Fernando Paiva Dorisbor, Tayana Serpa Ortiz Tanaka, Gabriela Alves Cesar, Sheila Araújo Teles, Simone Simionatto, Alisson Richard Teixeira Novais, Bruna Nepomuceno, Lisie Souza Castro, Barbara Vieira do Lago, Ana Rita Coimbra Motta-Castro
The aim of this multicenter, cross sectional study was to assess the prevalence, incidence and associated risk factors among incarcerated populations from twelve Brazilian prisons. The total of 3,368 individuals from twelve prisons was randomly recruited between March 2013 and March 2014. Participants were interviewed, and provided blood samples which were tested for antibodies to Hepatitis C (HCV ab). One year after the first investigation, a cohort study was conducted with 1,656 inmates who participated the cross sectional study...
2017: PloS One
https://www.readbyqxmd.com/read/28025726/management-of-hcv-infection-in-the-penitentiary-setting-in-the-direct-acting-antivirals-era-practical-recommendations-from-an-expert-panel
#10
REVIEW
Roberto Ranieri, Giulio Starnini, Sergio Carbonara, Emanuele Pontali, Guido Leo, Antonio Romano, Sandro Panese, Roberto Monarca, Tullio Prestileo, Giorgio Barbarini, Sergio Babudieri
BACKGROUND: The prevalence of HCV infection is higher among prisoners than in the general population. The introduction of HCV direct-acting antivirals (DAA) holds the potential to improve clinical outcomes also in inmates. However, treatment of hepatitis C in inmates has to face several clinical and logistical issues which are peculiar of prison environment. Recommendations on the management of HCV infection specific for the penitentiary setting in the DAA era remain scant. The Italian Society for Penitentiary Medicine and Healthcare has, therefore, issued these recommendations, to provide clinicians with a guide for the comprehensive management of HCV infection in the restriction setting, taking into account its peculiar characteristics...
April 2017: Infection
https://www.readbyqxmd.com/read/27922518/hepatitis-c-point-of-care-testing-in-vulnerable-populations-a-human-factors-study
#11
Donna M Zucker, Akshaya Shanmugam
One third of all hepatitis C virus (HCV) cases in the United States are incarcerated in jails and prisons. Hepatitis C virus testing is primarily accomplished through a clinical laboratory, yet point-of-care (POC) testing is less invasive and results are available in 20 minutes compared with up to 3 weeks. The purpose of this article was to describe the findings of a collaborative project between the Colleges of Engineering and Nursing at the University of Massachusetts Amherst in executing a human factors study for HCV antibody testing and screening...
November 2016: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/27921633/healthcare-resources-are-inadequate-to-address-the-burden-of-illness-among-hiv-infected-male-prisoners-in-malaysia
#12
Joseph Bick, Gabriel Culbert, Haider A Al-Darraji, Clayton Koh, Veena Pillai, Adeeba Kamarulzaman, Frederick Altice
Purpose Criminalization of drug use in Malaysia has concentrated people who inject drugs (PWID) and people living with HIV into prisons where health services are minimal and HIV-related mortality is high. Few studies have comprehensively assessed the complex health needs of this population. The paper aims to discuss these issues. Design/methodology/approach From October 2012 through March 2013, 221 sequentially selected HIV-infected male prisoners underwent a comprehensive health assessment that included a structured history, physical examination, and clinically indicated diagnostic studies...
December 19, 2016: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/27858889/correlates-of-infection-and-molecular-characterization-of-blood-borne-hiv-hcv-and-hbv-infections-in-hiv-1-infected-inmates-in-italy-an-observational-cross-sectional-study
#13
MULTICENTER STUDY
Nunzia Sanarico, Stefania D'Amato, Roberto Bruni, Claudia Rovetto, Emanuela Salvi, Patrizia Di Zeo, Paola Chionne, Elisabetta Madonna, Giulio Pisani, Angela Costantino, Michele Equestre, Maria E Tosti, Alessandra Cenci, Maria T Maggiorella, Leonardo Sernicola, Emanuele Pontali, Alfredo Pansera, Rocco Quattrocchi, Sergio Carbonara, Fabio Signorile, Lorenzo Antonio Surace, Guido Federzoni, Elisa Garlassi, Giulio Starnini, Roberto Monarca, Sergio Babudieri, Maria Rapicetta, Maria G Pompa, Anna Caraglia, Barbara Ensoli, Anna R Ciccaglione, Stefano Buttò
Coinfection of blood-borne hepatitis B and hepatitis C viruses (HBV and HCV, respectively) in human immunodeficiency virus type 1 (HIV-1)-positive individuals frequently occurs in inmate population and peculiar viral strains and patterns of virological markers may be observed.Plasma from 69 HIV-1-positive inmates was obtained from 7 clinical centers connected with correctional centers in different towns in Italy. HIV, HBV, and HCV markers were tested by commercial assays. Virus genotyping was carried out by sequencing the protease and reverse transcriptase-encoding region (PR-RT region) for HIV and a region encompassing the NS5B gene for HCV and subsequent phylogenetic analysis...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27815935/are-the-testing-needs-of-key-european-populations-affected-by-hepatitis-b-and-hepatitis-c-being-addressed-a-scoping-review-of-testing-studies-in-europe
#14
REVIEW
Jeffrey V Lazarus, Ida Sperle, Alexander Spina, Jürgen K Rockstroh
AIM: To investigate whether or not key populations affected by hepatitis B and hepatitis C are being tested sufficiently for these diseases throughout the European region. METHODS: We searched MEDLINE and EMBASE for studies on HBV and HCV testing in the 53 Member States of the World Health Organization European Region following PRISMA criteria. RESULTS: 136 English-language studies from 24 countries published between January 2007 and June 2013 were found...
October 31, 2016: Croatian Medical Journal
https://www.readbyqxmd.com/read/27778436/social-capital-strategies-to-enhance-hepatitis-c-treatment-awareness-and-uptake-among-men-in-prison
#15
L Lafferty, C Treloar, J Guthrie, G M Chambers, T Butler
Prisoner populations are characterized by high rates of hepatitis C (HCV), up to thirty times that of the general population in Australia. Within Australian prisons, less than 1% of eligible inmates access treatment. Public health strategies informed by social capital could be important in addressing this inequality in access to HCV treatment. Twenty-eight male inmates participated in qualitative interviews across three correctional centres in New South Wales, Australia. All participants had recently tested as HCV RNA positive or were receiving HCV treatment...
October 24, 2016: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/27776593/epidemiological-study-of-hepatitis-b-virus-among-prisoners-with-active-tuberculosis-in-central-brazil
#16
L M M Iglecias, M A M Puga, M A Pompílio, S A Teles, J Croda, L A Lima, B V Lago, R M B Martins, A R C Motta-Castro
BACKGROUND: Due to environmental and social conditions inherent to incarceration, tuberculosis (TB) and hepatitis B virus (HBV) are major diseases among prison inmates. OBJECTIVE: To determine overall and occult HBV infection (OBI) prevalence rates, risk factors and genotype distribution among inmates with active TB. STUDY DESIGN: A cross-sectional study was conducted among 216 inmates with active TB recruited at the largest prisons in Campo Grande, Mato Grosso do Sul, Central Brazil...
November 2016: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/27774690/a-nurse-led-intervention-improved-blood-borne-virus-testing-and-vaccination-in-victorian-prisons
#17
Rebecca J Winter, Bethany White, Stuart A Kinner, Mark Stoové, Rebecca Guy, Margaret E Hellard
OBJECTIVES: Testing is the first step in treatment and care for blood-borne viruses (BBVs) and sexually transmitted infections (STIs). As new treatments for viral hepatitis emerge, it is important to document effective models for BBV/STI testing. A nurse-led intervention was implemented across three prisons in Victoria to improve BBV/STI testing. We evaluated the impact of the intervention on BBV/STI testing rates and hepatitis B (HBV) vaccination for reception prisoners. METHODS: BBV/STI testing and HBV vaccination data were collected from the medical files of 100 consecutive reception prisoners at three prisons (n=300) prior to and after the intervention was implemented...
December 2016: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/27755143/syphilis-hepatitis-c-and-hiv-in-eastern-europe
#18
Heather Bailey, Anna Turkova, Claire Thorne
PURPOSE OF REVIEW: Eastern Europe and Central Asia (EECA) has experienced large-scale epidemics of syphilis, hepatitis C virus (HCV) and HIV over the past few decades. Here, we review recent evidence on the epidemiology of and the response to these intersecting epidemics. RECENT FINDINGS: The HIV epidemic in EECA continues to expand, with new infections increasing by more than 50% between 2010 and 2015. HCV is now in the top 10 causes of death in EECA, with Russia accounting for more than half of the global burden of HCV infections, but access to direct-acting antivirals remains a major obstacle for control of the epidemic...
February 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/27702964/new-hepatitis-c-drugs-are-very-costly-and-unavailable-to-many-state-prisoners
#19
Adam L Beckman, Alyssa Bilinski, Ryan Boyko, George M Camp, A T Wall, Joseph K Lim, Emily A Wang, R Douglas Bruce, Gregg S Gonsalves
Prisoners bear much of the burden of the hepatitis C epidemic in the United States. Yet little is known about the scope and cost of treating hepatitis C in state prisons-particularly since the release of direct-acting antiviral medications. In the forty-one states whose departments of corrections reported data, 106,266 inmates (10 percent of their prisoners) were known to have hepatitis C on or about January 1, 2015. Only 949 (0.89 percent) of those inmates were being treated. Prices for a twelve-week course of direct-acting antivirals such as sofosbuvir and the combination drug ledipasvir/sofosbuvir varied widely as of September 30, 2015 ($43,418-$84,000 and $44,421-$94,500, respectively)...
October 1, 2016: Health Affairs
https://www.readbyqxmd.com/read/27694729/hbv-and-hcv-serological-monitoring-among-injection-drugs-users-in-opiate-substitution-treatment-in-bosnia-and-herzegovina
#20
Sinisa Skocibusic, Marko Martinac, Jurica Arapovic, Svjetlana Grgic, Jadranka Nikolic, Dino Hasanagic, Milenko Bevanda, Jelena Ravlija
INTRODUCTION: Use of intravenous heroin carries a risk of serious medical conditions, including acquiring blood-borne infections. Therefore, hepatitis B virus (HBV) and hepatitis C virus (HCV) infection represent a threat for people who inject drugs (PWID). The objectives of this study were to determine the extent and characteristics of risk factors for acquiring HBV and HCV infection in PWID included in opiate substitution treatment in the southern part of Bosnia and Herzegovina (B&H)...
September 30, 2016: Journal of Infection in Developing Countries
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