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https://www.readbyqxmd.com/read/28820095/proposal-of-henriciella-barbarensis-sp-nov-and-henriciella-algicola-sp-nov-stalked-species-of-the-genus-and-emendation-of-the-genus-henriciella
#1
Wolf-Rainer Abraham, Maira Peres de Carvalho, Thais Souto Paula da Costa Neves, Marina Torquato Memoria, Iago Toledo Tartuci, Marc Vancanneyt, John Smit, Manfred Rohde
Two Gram-negative, heterotrophic, aerobic, prosthecated, marine bacteria, designated strains MCS23T and MCS27T, were isolated from seawater samples. NaCl was required for growth. The major polar lipid detected in strain MCS27T was phosphatidylglycerol, whereas those detected in MCS23T were phosphatidylglycerol, sulfoquinovosyl diacylglycerol and 1,2-diacyl-3-α-d-glucuronopyranosyl-sn-glycerol taurineamide. The most abundant cellular fatty acids were C18 : 1ω7 and C16 : 0, hydroxyl-fatty acids were 3-OH C12 : 0 in both strains and 3-OH C11 : 0 in MCS23T...
August 18, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28819044/the-parkinson-s-disease-associated-protein-dj-1-plays-a-positive-nonmitochondrial-role-in-endocytosis-in-dictyostelium-cells
#2
Suwei Chen, Sarah J Annesley, Rasha A F Jasim, Vanessa J Musco, Oana Sanislav, Paul R Fisher
The loss of function of DJ-1 caused by mutations of DJ-1 causes a form of familial Parkinson's Disease (PD). However, the role of DJ-1 in healthy and in PD cells is poorly understood. Even its subcellular localization in mammalian cells is uncertain, both cytosolic and mitochondrial locations having been reported. We show here that DJ-1 is normally located in the cytoplasm in healthy Dictyostelium discoideum cells. With its unique life cycle, straightforward genotype-phenotype relationships, experimental accesibility and genetic tractability, Dictyostelium discoideum offers an attractive model to investigate the roles of PD-associated genes...
August 17, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28817389/congenital-anomalies-of-the-optic-disc-insights-from-optical-coherence-tomography-imaging
#3
Karen W Jeng-Miller, Dean M Cestari, Eric D Gaier
PURPOSE OF REVIEW: Congenital anomalies of the optic nerve are rare but significant causes of visual dysfunction in children and adults. Accurate diagnosis is dependent on a thorough funduscopic examination, but can be enhanced by imaging information garnered from optical coherence tomography (OCT). We review common congenital optic nerve anomalies, including optic disc pit, optic nerve coloboma, morning glory disc anomaly, and hypoplasia of the optic nerve, review their systemic associations, and discuss insights from OCT imaging...
August 16, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28812406/types-of-orbital-osteoma-a-descriptive-analysis
#4
Tayyab Afghani, Hassan Mansoor
AIMS: This study describes different types of orbital osteoma based on clinical per-operative morphology and radiological findings to facilitate communication between ophthalmologists and surgical management for a better patient outcome. MATERIALS AND METHODS: The study was conducted in the Orbit and Oculoplastics Department of Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan, from July 1, 2001 to June 30, 2014. A retrospective analysis of 520 diagnosed orbital tumours who presented to us was carried out and the prevalence of orbital osteoma was determined...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28811881/self-and-intra-morph-incompatibility-and-selection-analysis-of-an-inconspicuous-distylous-herb-growing-on-the-tibetan-plateau-primula-tibetica
#5
Xian-Feng Jiang, Qing-Jun Li
There is discussion over whether pollen limitation exerts selection on floral traits to increase floral display or selects for traits that promote autonomous self-fertilization. Some studies have indicated that pollen limitation does not mediate selection on traits associated with either pollinator attraction or self-fertilization. Primula tibetica is an inconspicuous cross-fertilized plant that may suffer from pollen limitation. We conducted a selection analysis on P. tibetica to investigate whether pollen limitation results in selection for an increased floral display in case the evolution of autonomous self-fertilization has been difficult for this plant...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28811761/incidence-rates-of-major-diseases-of-kiwiberry-in-2015-and-2016
#6
Gyoung Hee Kim, Deok Ryong Kim, Sook-Young Park, Young Sun Lee, Jae Sung Jung, Young Jin Koh
Incidence rates of diseases in kiwiberry orchards were investigated monthly from late June to late September in Gwangyang and Boseong in 2015 and 2016. The impact of postharvest fruit rot was investigated during ripening after harvest. Bacterial canker was only observed on one single tree in 2015, but black rot, powdery mildew, leaf spot and blight, and postharvest fruit rot diseases were problematic throughout the study period in both 2015 and 2016. Incidence rates of the diseases varied with kiwiberry cultivar, region and sampling time...
August 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/28811312/myosin-ii-is-not-required-for-drosophila-tracheal-branch-elongation-and-cell-intercalation
#7
Amanda Ochoa-Espinosa, Stefan Harmansa, Emmanuel Caussinus, Markus Affolter
The Drosophila tracheal system consists of an interconnected network of monolayered epithelial tubes that ensures oxygen transport in the larval and adult body. During tracheal dorsal branch (DB) development, individual DBs elongate as a cluster of cells, led by tip cells at the front and trailing cells in the rear. Branch elongation is accompanied by extensive cell intercalation and cell lengthening of the trailing stalk cells. Although cell intercalation is governed by Myosin II (MyoII)-dependent forces during tissue elongation in the Drosophila embryo that lead to germ-band extension, it remained unclear whether MyoII plays a similar active role during tracheal branch elongation and intercalation...
August 15, 2017: Development
https://www.readbyqxmd.com/read/28810859/the-presence-of-ovarian-cysts-in-a-captive-antillean-manatee-trichechus-manatus-manatus-l-1758
#8
Karolina Goździewska-Harłajczuk, Joanna Klećkowska-Nawrot, Stanisław Dzimira
BACKGROUND: Several pathological changes associated with reproductive systems of marine mammals have been reported in primary literature. However, no such records exist regarding ovarian cysts in the Antillean manatee (Trichechus manatus manatus L. 1758). CASE PRESENTATION: A nulliparous female Antillean manatee, held in captivity at the Wroclaw Zoological Garden, died in April 2015. The animal was 370 cm long from nose to tail and weighed 670 kg. The width of manatee's fluke was 80 cm...
August 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28808938/advances-in-vaccines-to-prevent-viral-respiratory-illnesses-in-children
#9
Aleisha J Anderson, Tom L Snelling, Hannah C Moore, Christopher C Blyth
Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens. Acute lower respiratory infection (ALRI) of both bacterial and viral aetiology continues to impact global child health. Key bacterial pathogens including Streptococcus pneumoniae and Haemophilus influenza type b are specifically targeted with current vaccination programmes, while at present there are less effective strategies for the prevention of viral disease...
August 14, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28807912/safety-and-efficacy-of-mhaa4549a-a-broadly-neutralizing-monoclonal-antibody-in-a-human-influenza-a-challenge-model-a-phase-2-randomized-trial
#10
Jacqueline M McBride, Jeremy J Lim, Tracy Burgess, Rong Deng, Michael A Derby, Mauricio Maia, Priscilla Horn, Omer Siddiqui, Daniel Sheinson, Haiyin Chen-Harris, Elizabeth M Newton, Dimitri Fillos, Denise Nazzal, Carrie M Rosenberger, Maikke B Ohlson, Rob Lambkin-Williams, Hosnieh Fathi, Jeffrey M Harris, Jorge A Tavel
BACKGROUND: MHAA4549A, a human monoclonal antibody targeting the hemagglutinin stalk region of influenza A virus (IAV), is being developed as a therapeutic for patients hospitalized with severe IAV infection. Safety and efficacy of MHAA4549A were assessed in a randomized, double-blind, placebo-controlled, dose-ranging study in a human IAV-challenge model. METHODS: One hundred healthy volunteers were inoculated with A/Wisconsin/67/2005 (H3N2) IAV and, 24-36 hours later, administered a single intravenous dose of either placebo, MHAA4549A (400, 1200, or 3600 mg) or a standard oral dose of oseltamivir...
August 14, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28807344/pituicytoma-review-of-commonalities-and-distinguishing-features-among-ttf-1-positive-tumors-of-the-central-nervous-system
#11
REVIEW
Siba El Hussein, Cristina Vincentelli
Pituicytoma is a rare low-grade glial neoplasm that originates in the distribution of the neurohypophysis, including the posterior pituitary lobe and infundibular stalk. The tumor cells resemble pituicytes, which are specialized glial cells of the neurohypophysis. Pituicytoma can be misdiagnosed pre-operatively as a pituitary adenoma due to overlapping clinical and neuroimaging features between these two entities. Pituicytoma can also mimic other neoplasms of the sellar and parasellar regions microscopically - meningioma, schwannoma and pilocytic astrocytoma - and shares immunohistochemical expression of TTF-1 with spindle cell oncocytoma and granular cell tumor of the sellar region, suggesting a common histogenesis...
August 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28802798/most-common-sites-on-mri-of-intracranial-neoplastic-leptomeningeal-disease
#12
J Matthew Debnam, Rory R Mayer, T Linda Chi, Leena Ketonen, Jeffrey S Weinberg, Wei Wei, Morris D Groves, Nandita Guha-Thakurta
Neoplastic leptomeningeal disease (LMD) represents infiltration of the leptomeninges by tumor cells. Knowledge of the frequencies of locations of LMD on MRI may assist in early detection, help elucidate the process of leptomeningeal spread of cancer and understand how LMD affects the central nervous system. Our goal was to identify intracranial sites of neoplastic LMD predilection on MRI in patients with cytologically-proven LMD. The presence of FLAIR signal hyperintensity and T1-weighted post-contrast enhancement in the sulci of the supratentorial compartment and cerebellum and enhancement of the cranial nerves (CNs), basal cisterns, pituitary stalk, and ependymal surface of the lateral ventricles, as well as the presence of parenchymal metastasis were recorded...
August 9, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28801768/the-influence-of-particle-size-and-feedstock-of-biochar-on-the-accumulation-of-cd-zn-pb-and-as-by-brassica-chinensis-l
#13
Ruilun Zheng, Cui Li, Guoxin Sun, Zubin Xie, Jie Chen, Juying Wu, Qinghai Wang
Biochar produced from rice straw (RC) and maize stalk (MC) was amended to the heavy metal-contaminated soil to investigate the effects of different biochar feedstock and particle size (fine, moderate, coarse) on the accumulation of Cd, Zn, Pb, and As in Brassica chinensis L. (Chinese cabbage). The concentrations of Cd, Zn, and Pb in shoot were decreased by up to 57, 75, and 63%, respectively, after biochar addition (4%). Only MC decreased As concentration in B. chinensis L. shoots by up to 61%. Biochar treatments significantly decreased NH4NO3-extractable concentrations of Cd, Zn, and Pb in soil by 47-62, 33-66, and 38-71%, respectively, yet increased that of As by up to 147%...
August 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28799759/extraction-of-glucuronoarabinoxylan-from-quinoa-stalks-chenopodium-quinoa-willd-and-evaluation-of-xylooligosaccharides-produced-by-gh10-and-gh11-xylanases
#14
Daniel Martin Salas-Veizaga, Rodrigo Villagomez, Javier A Linares-Pastén, Cristhian Álvaro Carrasco, Maria Teresa Álvarez, Patrick Adlercreutz, Eva Nordberg-Karlsson
Byproducts from quinoa are not yet well explored sources of hemicellulose or products thereof. In this work, xylan from milled quinoa stalks was retrieved to 66% recovery by akaline extraction using 0.5 M NaOH at 80°C, followed by ethanol precipitation. The isolated polymer eluted as a single peak in SEC with a molecular weight >700 kDa. Analysis by FT-IR and NMR, combined with acid hydrolysis to monomers, showed that the polymer was built of a backbone of β-(1,4) linked xylose residues that were substituted by 4-O-methylglucuronic acids, arabinose and galactose in an approximate molar ratio of 114:23:5:1...
August 11, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28797976/physiological-mechanisms-of-water-and-electrolyte-disturbances-following-transsphenoidal-pituitary-surgery
#15
Evan T Blair, John S Clemmer, H Louis Harkey, Robert L Hester, W Andrew Pruett
BACKGROUND: Disturbances in water and electrolyte homeostasis are common following transsphenoidal surgery. These disorders are variable and unpredictable, increasing patient risk and complicating postsurgical treatment. Clinically, it is generally accepted that damage to the pituitary is the etiology, but the mechanisms behind the response variability and underlying pathophysiology remains unknown. OBJECTIVE: To test the hypothesis that changing the degree of damage to the pituitary stalk produces a spectrum of water and electrolyte disturbance along which all presentations of postsurgical water and electrolyte disturbances can be identified...
August 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28794931/improved-production-of-kojic-acid-by-mutagenesis-of-aspergillus-flavus-hak1-and-aspergillus-oryzae-hak2-and-their-potential-antioxidant-activity
#16
Hala A M Ammar, Saeid M Ezzat, Asmaa M Houseny
Two wild-type (WT) Aspergillus strains, A. flavus HAk1 and A. oryzae HAk2, were selected for kojic acid (KA) biosynthesis. Malt extract sucrose culture medium (MES) was the best culture medium for maximum production of KA. The maximum production of KA has been estimated at pH 4 after 7 days of incubation at 30 °C. Overproduction of KA was attained by mutagenesis of both A. flavus HAk1 and A. oryzae HAk2 through their exposer to different doses of gamma irradiation. The mutant strains (MT) A. flavus HAk1-M2 and A...
October 2017: 3 Biotech
https://www.readbyqxmd.com/read/28791597/biochar-increased-photosynthetic-and-accessory-pigments-in-tomato-solanum-lycopersicum-l-plants-by-reducing-cadmium-concentration-under-various-irrigation-waters
#17
Muhammad Abid, Subhan Danish, Muhammad Zafar-Ul-Hye, Muhammad Shaaban, Muhammad Mutahir Iqbal, Abdur Rehim, Muhammad Farooq Qayyum, Muhammad Nadir Naqqash
Fresh surface water supplies are gradually becoming insufficient in arid and semi-arid regions of the world. Thus, farmers in these areas are being forced to use poor quality sewage water. Irrigating vegetable crops with sewage water having high metal concentration may affect growth and biochemical processes of plants. Biochar (BC) can sorb these metals and may reduce their toxic effects on plants. Thus, a greenhouse experiment was conducted to study the influence of cotton stalks derived biochar (CSDB) at control (0%) and 1%; ground water (GW; 0...
August 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28777992/physico-chemical-pretreatment-and-enzymatic-hydrolysis-of-cotton-stalk-for-ethanol-production-by-saccharomyces-cerevisiae
#18
Anita Singh, Somvir Bajar, Narsi R Bishnoi
The aim of this work was to study the physico-chemical pretreatment and enzymatic hydrolysis of cotton stalk for ethanol production by Saccharomyces cerevisiae. Firstly, factors affecting pretreatment were screened out by Plackett-Burman design (PBD) and most significant factors were further optimized by Box-Behnken design (BBD). As shown by experimental study, most significant factors were FeCl3 concentration (FC), irradiation time (IT) and substrate concentration (SC) affecting pretreatment of cotton stalk among all studied factors...
July 23, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28776642/diagnosis-of-monogenic-liver-diseases-in-childhood-by-next-generation-sequencing
#19
Amelie Stalke, Britta Skawran, Bernd Auber, Thomas Illig, Brigitte Schlegelberger, Norman Junge, Imeke Goldschmidt, Christoph Leiskau, Nils von Neuhoff, Ulrich Baumann, Eva-Doreen Pfister
Next-Generation Sequencing (NGS) has opened up novel diagnostic opportunities for children with unidentified, but suspected inherited diseases. We describe our single-center experience with NGS diagnostics in standard clinical scenarios in pediatric hepatology. We investigated 135 children with suspected inherited hepatopathies, where initially no causative pathogenic variant had been identified, with an amplicon-based NGS panel of 21 genes associated with acute and chronic hepatopathies. In 23 of these patients we detected pathogenic or likely pathogenic variants in ten different genes...
August 4, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28775260/phytoextraction-of-cadmium-contaminated-soil-and-potential-of-regenerated-tobacco-biomass-for-recovery-of-cadmium
#20
Yang Yang, Yichen Ge, Hongyuan Zeng, Xihong Zhou, Liang Peng, Qingru Zeng
The aim of this study was to estimate the influence of regenerated tobacco on the extraction of Cd from two acidic soils as well as to address the problem of how to deal with contaminated leaves following phytoextraction. Results showed that a coppicing tobacco led to a decline in Cd concentration in regenerated leaves and stalks when plants were grown in pots, but increased concentrations in regenerated lower and middle leaves when plants were grown under field conditions. The highest recorded bioconcentration factors in Chaling and Guanxi soil were 37...
August 3, 2017: Scientific Reports
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