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https://www.readbyqxmd.com/read/29343033/-clinical-features-and-prognosis-of-18-cases-of-primary-lymphocytic-hypophysitis
#1
Q Wei, G Q Yang, Y J Li, L Zang, Y Pei, J Du, W J Gu, J M Ba, Z H Lü, J T Dou, Y M Mu, J M Lu
Objective: To analyze clinical features, prognosis and treatment of lymphocytic hypophysitis (LYH). Methods: The clinical data, treatments and outcomes of 18 cases diagnosed as LYH at Chinese PLA General Hospital between January 2001 and July 2017 was respectively reviewed. Results: Eighteen patients with histology-proven LYH (13 females and 5 males ) were identified. All lymphocytic adenohypophysitis (LAH) were females(n=6), two of whom were associated with pregnancy. Eleven patients (6 females and 5 males) had lymphocytic panhypophysitis (LPH) and one(female) had hypothalamitis...
January 9, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29340628/the-importance-of-umbilical-blood-supply-and-umbilical-delay-in-secondary-abdominoplasty-a-case-report
#2
Fereydoun Don Parsa, Justin Cheng, Michael S Hu, Leslie Kim, Nikki Castel, Alan A Parsa
The umbilicus is an important aesthetic landmark of the abdomen. It possesses a dual blood supply that allows it to survive either on its stalk if the skin surrounding the umbilicus is incised, or through the surrounding subdermal circulation if the stalk is transected. This is an important concept to consider in order to avoid umbilical ischemia and necrosis during abdominoplasty, especially if there is any past surgical history suggesting alteration to its blood supply. This case study depicts this importance and the importance of the use of delay in order to improve perfusion to the umbilicus prior to secondary abdominoplasty...
January 11, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29336227/extracts-from-lupinus-albescens-antioxidant-power-and-antifungal-activity-in-vitro-against-phytopathogenic-fungi
#3
Tássia C Confortin, Izelmar Todero, Juliana F Soares, Luciana Luft, Thiarles Brun, Jéssica E Rabuske, Cicero U Nogueira, Marcio A Mazutti, Giovani L Zabot, Marcus V Tres
Fungi are considered the most damaging microorganisms in agriculture. The indiscriminate use of chemical treatments in agricultural products causes the development of pest resistance and affects human health. An alternative to synthetic fungicides is the use of natural products such as plant extracts for the management of fungal diseases in plants. Extracts from different parts of Lupinus albescens (roots, stalks, leaves, and flowers) were obtained by extraction using supercritical carbon dioxide (CO2) or compressed liquefied petroleum gas (LPG)...
January 16, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29331671/the-molecular-characteristics-of-avian-influenza-viruses-h9n2-derived-from-air-samples-in-live-poultry-markets
#4
Yanheng Wu, Jinsi Lin, Shuhuan Yang, Ying Xie, Man Wang, Xueqin Chen, Yayang Zhu, Le Luo, Wuyang Shi
OBJECTIVE: To study the molecular characteristics of H9N2-subtype avian influenza viruses (AIVs) isolated from air samples collected in live poultry markets (LPMs) and explore their sequence identities with AIVs that caused human infection. METHODS: Weekly surveillance of H9N2-subtype AIVs in the air of LPMs was conducted from 2015 to 2016. H9-positive samples were isolated from chicken embryos. Whole genome sequences of the isolated AIVs were obtained through high-throughput sequencing...
January 10, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29331537/preparation-of-acetylated-nanofibrillated-cellulose-from-corn-stalk-microcrystalline-cellulose-and-its-reinforcing-effect-on-starch-films
#5
Li Cheng, Dongli Zhang, Zhengbiao Gu, Zhaofeng Li, Yan Hong, Caiming Li
Acetylated nanofibrillated cellulose (ANFC) with different degrees of substitution (DS) was prepared from corn-stalk microcrystalline cellulose (MCC) using chemical-mechanical combined processes. The physicochemical properties of nanofibrillated cellulose (NFC) and ANFC were investigated together with the influence of added nanoparticles on the mechanical properties of starch films. The acetylation reaction was monitored by Fourier transform infrared (FT-IR) and titration. Particle size and morphological of NFC and ANFC were studied by atomic force microscope (AFM)...
January 10, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29330299/effects-of-allelic-variations-in-the-human-myxovirus-resistance-protein-a-on-its-antiviral-activity
#6
Laura Graf, Alexej Dick, Franziska Sendker, Emanuel Barth, Manja Marz, Oliver Daumke, Georg Kochs
Only a minority of patients infected with seasonal influenza A viruses exhibits a severe or fatal outcome of infection, but the reasons for this inter-individual variability in influenza susceptibility are unclear. To gain further insights into the molecular mechanisms underlying this variability, we investigated naturally occurring allelic variations of the myxovirus resistance 1 (MX1) gene coding for the influenza restriction factor MxA. The interferon-induced dynamin-like GTPase consists of an N-terminal GTPase domain, a bundle signaling element, and a C-terminal stalk responsible for oligomerization and viral target recognition...
January 12, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29325745/chitosan-nanoparticles-cellulose-nanocrystals-nanocomposites-as-a-carrier-system-for-the-controlled-release-of-repaglinide
#7
Wafaa S Abo Elseoud, Mohammad L Hassan, Magdy W Sabaa, Mona Basha, Enas A Hassan, Shaimaa M Fadel
The aim of the present work was to study the use of cellulose nanocrystals (CNC) and chitosan nanoparticles (CHNP) for developing controlled-release drug delivery system of the anti-hyperglycemic drug Repaglinide (RPG). CNC was isolated from palm fruit stalks by sulfuric acid hydrolysis; the dimensions of the isolated nanocrystals were 86-237 nm in length and 5-7 nm in width. Simple and economic method was used for the fabrication of controlled release drug delivery system from CNC and CHNP loaded with RPG drug via ionic gelation of chitosan in the presence of CNC and RPG...
January 8, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29324225/the-marburgvirus-neutralizing-human-monoclonal-antibody-mr191-targets-a-conserved-site-to-block-virus-receptor-binding
#8
Liam B King, Marnie L Fusco, Andrew I Flyak, Philipp A Ilinykh, Kai Huang, Bronwyn Gunn, Robert N Kirchdoerfer, Kathryn M Hastie, Amandeep K Sangha, Jens Meiler, Galit Alter, Alexander Bukreyev, James E Crowe, Erica Ollmann Saphire
Since their first identification 50 years ago, marburgviruses have emerged several times, with 83%-90% lethality in the largest outbreaks. Although no vaccines or therapeutics are available for human use, the human antibody MR191 provides complete protection in non-human primates when delivered several days after inoculation of a lethal marburgvirus dose. The detailed neutralization mechanism of MR191 remains outstanding. Here we present a 3.2 Å crystal structure of MR191 complexed with a trimeric marburgvirus surface glycoprotein (GP)...
January 10, 2018: Cell Host & Microbe
https://www.readbyqxmd.com/read/29324085/hyperparasitism-of-an-avian-ectoparasitic-hippoboscid-fly-ornithomya-anchineuria-by-the-mite-myialges-cf-borealis-in-alberta-canada
#9
Cameron P Goater, Jayden Dyck, Heather Proctor, Kevin Floate
Hippoboscid flies (Diptera: Hippoboscidae) include species that are ectoparasites of birds in the Northern Hemisphere, but little is known regarding their taxonomy, parasites, avian host associations, or geographical distribution in North America. In late August of 2013 and 2014, we collected hippoboscid flies from live birds trapped in mist nets as part of a banding study in Cypress Hills Interprovincial Park in southeastern Alberta, Canada. A total of 113 birds comprising 9 species was examined in 2013. Of these, 18 individuals were infested with 1-3 Ornithomya anchineuria Speiser (n = 22 flies; prevalence = 15...
January 11, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29322554/transcription-factor-foxc1-is-involved-in-anterior-part-of-cranial-base-formation
#10
Nandar Mya, Toshiko Furutera, Shigeru Okuhara, Tsutomu Kume, Masaki Takechi, Sachiko Iseki
The cranial base is a structure mainly formed through endochondral ossification, and integrated into the craniofacial complex acting as an underlying platform for developing brain. Foxc1 is an indispensable regulator during intramembranous and endochondral ossification. In this study, we found that the spontaneous loss of Foxc1 function mouse (congenital hydrocephalous), Foxc1ch/ch , showed the anterior cranial base defects including unossified presphenoid and lack of middle part of the basisphenoid bone. Consistently, hypoplastic presphenoid primordial cartilage (basal portion of the trabecular cartilage) and lack of the middle part of basisphenoid primordial cartilage (the hypophyseal cartilage) were observed at earlier developmental stage...
January 11, 2018: Congenital Anomalies
https://www.readbyqxmd.com/read/29320922/co-emergence-of-specialized-endothelial-cells-from-embryonic-stem-cells
#11
Nicole Madfis, Zhiqiang Lin, Ashwath Kumar, Simone A Douglas, Manu O Platt, Yuhong Fan, Kara E McCloskey
A well-formed and robust vasculature is critical to the health of most organ systems in the body. However, the endothelial cells (ECs) forming the vasculature can exhibit a number of distinct functional subphenotypes like arterial or venous ECs, as well as angiogenic tip and stalk ECs. Here, we investigate the in vitro differentiation of EC subphenotypes from embryonic stem cells (ESCs) using. Using our staged induction methods and chemically-defined mediums, highly angiogenic EC subpopulations, as well as, less proliferative and less migratory EC subpopulations are derived...
January 10, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29317365/intraoperative-mri-guided-biopsy-in-the-diagnosis-of-suprasellar-langerhans-cell-histiocytosis
#12
Kate T Carroll, Bryson C Lochte, James Y Chen, Vivian S Snyder, Bob S Carter, Clark C Chen
Magnetic resonance imaging (MRI)-guided biopsy is an emerging diagnostic technique that holds great promise for otherwise difficult to access neuroanatomy. Here we describe MRI-guided biopsy of a suprasellar lesion located posterior and superior to the pituitary stalk. The approach was successfully implemented in a 38-year-old woman who had developed progressive visual deterioration. Intra-operative MRI revealed the need for trajectory adjustment due to an unintended, minor deviation in the burr hole entry point, demonstrating the benefit of an MRI-guided approach...
January 6, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29306508/a-virus-like-particle-vaccine-candidate-for-influenza-a-virus-based-on-multiple-conserved-antigens-presented-on-hepatitis-b-tandem-core-particles
#13
Alejandro Ramirez, Stephen Morris, Sophie Maucourant, Isabella D'Ascanio, Vincenzo Crescente, I-Na Lu, Sophie Farinelle, Claude P Muller, Michael Whelan, William Rosenberg
Existing Influenza A virus (IAV) vaccines target variable parts of the virus that may change between seasons. Vaccine design relies on predicting the predominant circulating influenza strains but when there is a mismatch between vaccine and circulating strains, efficacy is sub-optimal. Furthermore, current approaches provide limited protection against emerging influenza strains that may cause pandemics. One solution is to design vaccines that target conserved protein domains of influenza, which remain largely unchanged over time and are likely to be found in emergent variants...
January 3, 2018: Vaccine
https://www.readbyqxmd.com/read/29305582/publisher-correction-natural-and-directed-antigenic-drift-of-the-h1-influenza-virus-hemagglutinin-stalk-domain
#14
Christopher S Anderson, Sandra Ortega, Francisco A Chaves, Amelia M Clark, Hongmei Yang, David J Topham, Marta L DeDiego
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
January 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29300013/structure-of-the-glucagon-receptor-in-complex-with-a-glucagon-analogue
#15
Haonan Zhang, Anna Qiao, Linlin Yang, Ned Van Eps, Klaus S Frederiksen, Dehua Yang, Antao Dai, Xiaoqing Cai, Hui Zhang, Cuiying Yi, Can Cao, Lingli He, Huaiyu Yang, Jesper Lau, Oliver P Ernst, Michael A Hanson, Raymond C Stevens, Ming-Wei Wang, Steffen Reedtz-Runge, Hualiang Jiang, Qiang Zhao, Beili Wu
Class B G-protein-coupled receptors (GPCRs), which consist of an extracellular domain (ECD) and a transmembrane domain (TMD), respond to secretin peptides to play a key part in hormonal homeostasis, and are important therapeutic targets for a variety of diseases. Previous work has suggested that peptide ligands bind to class B GPCRs according to a two-domain binding model, in which the C-terminal region of the peptide targets the ECD and the N-terminal region of the peptide binds to the TMD binding pocket. Recently, three structures of class B GPCRs in complex with peptide ligands have been solved...
January 3, 2018: Nature
https://www.readbyqxmd.com/read/29295036/adverse-consequences-to-assisting-victims-of-campus-violence-initial-investigations-among-college-students
#16
Alison Krauss, Ernest N Jouriles, Kristen Yule, John H Grych, Kelli S Sargent, Victoria L Banyard
Despite growing interest in the use of bystander education programs to address the problems of sexual and relationship violence on college campuses, little knowledge exists on adverse consequences experienced by students intervening as a bystander. The current study examined the prevalence and correlates of adverse consequences of bystander intervention in two samples of first-year college students. In Study 1, 281 students completed a measure of negative consequences experienced when acting as a bystander to help someone at risk of sexual assault, relationship abuse, or stalking...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29294957/assessing-the-link-between-intimate-partner-violence-and-postrelationship-stalking-a-gender-inclusive-study
#17
Svenja Senkans, Troy E McEwan, James R P Ogloff
The link between intimate partner violence (IPV) during a relationship and postrelationship stalking (PRS) is poorly understood. The vast majority of relevant studies focus either on male perpetration or female victimization and use highly selective samples. The current study aimed to illuminate the link between IPV and PRS perpetration and victimization, respectively. To this end, heterosexual male and female university students ( n = 422) retrospectively self-reported on IPV during their most conflicted relationship and a wide range of pursuit behavior after the dissolution of this romantic relationship...
October 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29294903/intimate-partner-violence-and-women-s-mental-health-the-mediating-role-of-coping-strategies-among-women-seeking-help-from-the-police
#18
Cecilia Mengo, Eusebius Small, Beverly Black
Many variables explain the link between intimate partner violence (IPV) and its impact on women's mental health. This proposition is mostly from samples drawn from battered women's shelters, batterer intervention programs (BIPs), emergency rooms, and medical clinics. We know little about the psychological well-being of women who report abuse to police departments. This study used data from case records of women who experience IPV and sought help from a city police station located in the southwest United States...
September 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29294898/power-and-inequality-intimate-partner-violence-against-bisexual-and-non-monosexual-women-in-the-united-states
#19
Bethany M Coston
While just over one in three heterosexual women will experience intimate partner violence (IPV) in her lifetime, 61% of bisexual women and 78% of non-monosexual women will. Combining previous research and theories on power, social resources, binegativity, and gender-based violence, this article analyzes the role of power and inequality in non-monosexual women's IPV victimization. Using data from the National Intimate Partner and Sexual Violence Survey, this article first examines rates of IPV victimization for statistically significant differences between monosexual (e...
August 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29294863/the-intersection-of-gender-identity-and-violence-victimization-experienced-by-transgender-college-students
#20
Stacey B Griner, Cheryl A Vamos, Erika L Thompson, Rachel Logan, Coralia Vázquez-Otero, Ellen M Daley
College students disproportionately experience victimization, stalking, and relationship violence when compared with other groups. Few studies explore victimization by the gender identity of college students, including those who identify as transgender. The purpose of this study is to explore the rates of violence experienced by transgender students compared with male and female college students. This study utilized the National College Health Assessment-II (NCHA-II) and included data from students ( n = 82,538) across fall 2011, 2012, and 2013...
August 1, 2017: Journal of Interpersonal Violence
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