Luke Sheridan Rains, Louise Marston, Mark Hinton, Steven Marwaha, Thomas Craig, David Fowler, Michael King, Rumana Z Omar, Paul McCrone, Jonathan Spencer, Joanne Taylor, Sophie Colman, Catherine Harder, Eleanor Gilbert, Amie Randhawa, Kirsty Labuschagne, Charlotte Jones, Theodora Stefanidou, Marina Christoforou, Meghan Craig, John Strang, Tim Weaver, Sonia Johnson
BACKGROUND: Cannabis is the most commonly used illicit substance amongst people with psychosis. Continued cannabis use following the onset of psychosis is associated with poorer functional and clinical outcomes. However, finding effective ways of intervening has been very challenging. We examined the clinical and cost-effectiveness of adjunctive contingency management (CM), which involves incentives for abstinence from cannabis use, in people with a recent diagnosis of psychosis. METHODS: CIRCLE was a pragmatic multi-centre randomised controlled trial...
August 15, 2019: BMC Medicine