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osteonecrosis of the femoral head

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https://www.readbyqxmd.com/read/28216761/management-of-osteonecrosis-of-the-femoral-head-a-novel-technique
#1
Ashwani Soni, Ravi K Gupta
No abstract text is available yet for this article.
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28210032/a-histomorphometric-study-of-necrotic-femoral-head-in-rabbits-treated-with-extracorporeal-shock-waves
#2
Huan-Zhi Ma, Dong-Sheng Zhou, Dong Li, Wei Zhang, Bing-Fang Zeng
[Purpose] This study aimed to determine the effectiveness and mechanisms of extracorporeal shock wave therapy in the treatment of femoral head osteonecrosis. [Subjects and Methods] Histomorphometric analysis of necrotic femoral head in rabbits treated with shock waves was performed. Bilateral osteonecrosis of femoral heads was induced with methylprednisolone and lipopolysaccharide in eight rabbits. The left limb (study side) received shock waves to the femoral head. The right limb (control side) received no shock waves...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28207735/long-non-coding-rna-hotair-inhibits-mir-17-5p-to-regulate-osteogenic-differentiation-and-proliferation-in-non-traumatic-osteonecrosis-of-femoral-head
#3
Biaofang Wei, Wei Wei, Baoxiang Zhao, Xiaxia Guo, Song Liu
BACKGROUND AND AIM: The biological functions of non-coding RNAs (ncRNAs) have been widely identified in many human diseases. In the present study, the relationship between long non-coding RNA HOTAIR and microRNA-17-5p (miR-17-5p) and their roles in osteogenic differentiation and proliferation in non-traumatic osteonecrosis of femoral head (ONFH) were investigated. METHODS: The expression levels of HOTAIR and miR-17-5p in the mesenchymal stem cells (MSCs) derived from patients with non-traumatic ONFH and osteoarthritis (OA) were examined by real-time PCR...
2017: PloS One
https://www.readbyqxmd.com/read/28197752/surgical-dislocation-for-pediatric-and-adolescent-hip-deformity-clinical-and-radiographical-results-at-3%C3%A2-years-follow-up
#4
Nicola Guindani, Oliver Eberhardt, Thomas Wirth, Michele F Surace, Francisco F Fernandez
INTRODUCTION: The aim of this study is to evaluate the clinical, radiographic short-term results and complications after surgical hip dislocation in young patients (≤18 years). MATERIALS AND METHODS: Clinical and radiographic outcomes were assessed in patients who underwent a surgical hip dislocation Ganz-type approach between 2008 and 2012. Diagnosis included Legg-Calvé-Perthes disease, slipped capital femoral epiphysis, femoroacetabular impingement, osteonecrosis of the femoral head, multiple hereditary exostoses and pigmented villonodular synovitis...
February 14, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28167850/hip-osteonecrosis-is-associated-with-increased-plasma-il-33-level
#5
Jinhui Ma, Wanshou Guo, Zirong Li, Bailiang Wang, Shirui Li, Peng Wang
The recently discovered IL-33 as an IL-1 cytokine family member has been proved to be specifically released from osteonecrotic bones. We aimed to investigate the potential role of IL-33 in the development of osteonecrosis of femoral head (ONFH). Forty patients diagnosed with ONFH and forty age-, sex-, and body mass index- (BMI-) matched healthy subjects were included in this prospective study between March 2016 and September 2016. A commercially available ELISA kit was used to test the level of plasma IL-33...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28162838/evidence-for-the-use-of-cell-based-therapy-for-the-treatment-of-osteonecrosis-of-the-femoral-head-a-systematic-review-of-the-literature
#6
Nicolas S Piuzzi, Jorge Chahla, John B Schrock, Robert F LaPrade, Cecilia Pascual-Garrido, Michael A Mont, George F Muschler
BACKGROUND: Cell-therapy has been promoted among the therapeutic arsenal that can aid in bone formation and remodeling, in early stages of osteonecrosis of the femoral head (ONFH). The purpose of this systematic review was to assess the evidence supporting the (1) clinical efficacy; (2) structural modifying effect, as evaluated radiographically; (3) revision rates; and (4) safety of cell-therapy for the treatment of ONFH. METHODS: A systematic review was performed including studies with a level-of-evidence of III or higher...
January 12, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28155827/bilateral-osteonecrosis-of-the-femoral-and-humeral-heads-after-short-term-corticosteroid-therapy-a-case-study
#7
Tarek Ahmed El Gamal, Ahmed El-Bakoury, Amanda Hawkins, Moham Ed AlTayeb Mussa, Tam Er Ahmed Sweed, Sam Eh Samir Ansara
Steroid induced osteonecrosis is a devastating injury that usually requires rebuild of the joint, with the femoral and the humeral head being most commonly affected. Steroid therapy is the most common reported cause of atraumatic osteonecrosis. The Collaborative Osteonecrosis Group Study confirmed that steroids are the primary cause of multi-focal osteonecrosis in 91% of the cases. Osteonecrosis is considered multifocal when three or more joints are involved. We report a rare case of bilateral steroid-induced osteonecrosis of the proximal femora and humeri nine months after a short course of intravenous methylprednisolone for treatment of multiple myeloma...
March 23, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28148658/long-term-outcomes-of-transtrochanteric-rotational-osteotomy-for-non-traumatic-osteonecrosis-of-the-femoral-head
#8
D Morita, Y Hasegawa, T Okura, Y Osawa, N Ishiguro
AIMS: Transtrochanteric rotational osteotomy (TRO) is performed for young patients with non-traumatic osteonecrosis of the femoral head (ONFH) to preserve the hip. We aimed to investigate the long-term outcomes and the risk factors for failure 15 years after this procedure. PATIENTS AND METHODS: This study included 95 patients (111 hips) with a mean age of 40 years (21 to 64) who underwent TRO for ONFH. The mean follow-up was 18.2 years (3 to 26). Kaplan-Meier survivorship analyses were performed with conversion to total hip arthroplasty (THA) and radiological failure due to secondary collapse of the femoral head or osteoarthritic changes as the endpoint...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28144608/the-current-perspectives-of-stem-cell-therapy-in-orthopedic-surgery
#9
REVIEW
Serkan Akpancar, Oner Tatar, Hasan Turgut, Faruk Akyildiz, Safak Ekinci
CONTEXT: Musculoskeletal injuries may be painful, troublesome, life limiting and also one of the global health problems. There has been considerable amount of interest during the past two decades to stem cells and tissue engineering techniques in orthopedic surgery, especially to manage special and compulsive injuries within the musculoskeletal system. EVIDENCE ACQUISITION: The aim of this study was to present a literature review regarding the most recent progress in stem cell procedures and current indications in orthopedics clinical care practice...
December 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/28143470/current-use-of-autologous-adipose-tissue-derived-stromal-vascular-fraction-cells-for-orthopedic-applications
#10
REVIEW
Jaewoo Pak, Jung Hun Lee, Kwang Seung Park, Moonhee Park, Lin-Woo Kang, Sang Hee Lee
Autologous adipose stromal vascular fractions (SVFs) containing adipose tissue-derived stem cells (ASCs) are currently being used in clinical settings for various orthopedic applications for human patients. Due to its potential capability of regenerating cartilage, bone, and tendons, autologous adipose SVFs are being tried in treating patients with osteoarthritis (OA), chondromalacia, meniscus tear, osteonecrosis of the femoral head, and tendon injuries. Here, we have reviewed available human clinical studies with regard to patient applications of autologous adipose SVF containing ASCs, specifically assessing effectiveness and safety in the field of orthopedic disorders...
January 31, 2017: Journal of Biomedical Science
https://www.readbyqxmd.com/read/28134048/surgical-treatment-for-pipkin-type-iv-femoral-head-fracture
#11
Yi-Hsun Yu, Yung-Heng Hsu, Ying-Chao Chou, I-Chuan Tseng, Chun-Yi Su, Chi-Chung Wu
PURPOSE: Pipkin type IV femoral head (FH) fracture was thought as poor prognosis. There were several surgical approaches and treatments for this difficult fracture. However, there was no one treatment superior to another. We reviewed a serious of patients with Pipkin type IV FH fracture underwent surgery via a modified Gibson approach. METHODS: We reviewed a consecutive series of nine patients with Pipkin type IV FH fracture under surgery via a modified Gibson approach between 2012 and 2013...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28127740/inverted-femoral-head-graft-versus-standard-core-decompression-in-nontraumatic-hip-osteonecrosis-at-minimum-3-years-follow-up
#12
Asser A Sallam, Mohamed A Imam, Khaled S Salama, Osman A Mohamed
PURPOSE: Numerous salvage surgeries were popularised to halt the progression of hip osteonecrosis (ON). We aimed to compare the clinico-radiological outcomes of inverted femoral head graft (IFHG) versus standard core decompression (SCD) in treatment of nontraumatic hip ON at pre-arthritic stage. METHODS: A case review was performed at a minimum 3 years follow-up of 61 patients (71 hips; mean age 32.96 (19-50) years; mean follow-up 7.86 (3-14) years; mean body mass index 28...
January 24, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28121934/extracorporeal-shockwave-therapy-in-osteonecrosis-of-femoral-head-a-systematic-review-of-now-available-clinical-evidences
#13
Qingyu Zhang, Lihua Liu, Wei Sun, Fuqiang Gao, Liming Cheng, Zirong Li
BACKGROUND: Osteonecrosis is an incapacitating disorder with high morbidity. Though extracorporeal shockwave therapy (ESWT) provides a noninvasive treatment option, controversial subjects still exist about its effectiveness, indications, and mechanism of action. METHODS: An electronic databases search was performed using PubMed, Embase, and the Cochrane library to collect clinical trials, case reports, and cases series on this topic and then useful data were extracted and appraised by experienced clinicians...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28108757/degeneration-of-articular-cartilage-in-osteonecrosis-of-the-femoral-head-begins-at-the-necrotic-region-after-collapse-a-preliminary-study-using-t1-rho-mri
#14
Kazuhiko Sonoda, Goro Motomura, Satoshi Kawanami, Yukihisa Takayama, Hiroshi Honda, Takuaki Yamamoto, Yasuharu Nakashima
OBJECTIVE: The purpose of this study is to evaluate the role of collapse on the degeneration of articular cartilage in patients with osteonecrosis of the femoral head (ONFH). MATERIALS AND METHODS: Sixteen hips in 12 patients (four men, eight women; mean age, 34.8 years) with a history of systemic corticosteroid treatment were studied using T1 rho magnetic resonance imaging (MRI). Six hips had collapsed ONFH, five had non-collapsed ONFH, and five had no osteonecrosis (controls)...
January 21, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28106675/treatment-of-slipped-capital-femoral-epiphysis-with-the-modified-dunn-procedure-a-multicenter-study
#15
Masquijo J Javier, Allende Victoria, D'Elia Martín, Miranda Gabriela, Fernández Claudio A
INTRODUCTION: Treatment of moderate to severe slipped capital femoral epiphysis (SCFE) is controversial. Over the last years, 3 institutions in Argentina adopted the modified Dunn procedure for capital realignment in selected cases of SCFE. Our aim in this study was to evaluate the clinical outcome and the rate of complications of patients who had undergone surgical hip dislocation and capital realignment. METHODS: A multicenter retrospective cohort study of patients who received the modified Dunn procedure from January 2009 to 2013 was performed...
January 18, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28106233/a-novel-digital-templating-methodology-for-arthroplasty-experience-from-patients-with-osteonecrosis-of-the-femoral-head
#16
Ning Dong, Chen Yang, Shu-Qiang Li, Yu-Hang Gao, Jian-Guo Liu, Xin Qi
PURPOSE: To assess the accuracy of a novel digital templating methodology for total hip arthroplasty (THA) in patients with osteonecrosis of the femoral head (ONFH). METHODS: A retrospective study was carried out on 77 hips in 58 patients who had undergone uncemented THA for ONFH. Preoperative radiographs were templated using a 2-step procedure: (i) calculation of basic cup and stem sizes based on the anatomical morphology; (ii) adjustment of the basic sizes to account for variables such as femoral external rotation, osteoporotic changes in the femur, osteosclerotic changes in the acetabulum, and the type of stem...
January 20, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28103867/efficacy-of-teriparatide-in-the-treatment-of-nontraumatic-osteonecrosis-of-the-femoral-head-a-retrospective-comparative-study-with-alendronate
#17
Ryuta Arai, Daisuke Takahashi, Masahiro Inoue, Tohru Irie, Tsuyoshi Asano, Takuya Konno, Mohamad Alaa Terkawi, Tomohiro Onodera, Eiji Kondo, Norimasa Iwasaki
BACKGROUND: Collapse of the femoral head associated with nontraumatic osteonecrosis (NOFH) is one of the most common causes of disability in young adult patients. Excessive bone resorption by osteoclast coincident with the suppression of osteogenesis are believed to be responsible for collapse progression. Alendronate that inhibits bone resorption by inducing osteoclast apoptosis has been traditionally used for treating NOFH; however, several reports documented serious complications by the use of this drug...
January 19, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28092922/the-effectiveness-of-free-vascularized-fibular-flaps-in-osteonecrosis-of-the-femoral-head-and-neck-a-systematic-review
#18
Cassandra A Ligh, Jonas A Nelson, John P Fischer, Stephen J Kovach, L Scott Levin
Background Free vascularized fibular flaps (FVFFs) are accepted surgical options to treat osteonecrosis of the femoral head and neck (ONFHN) to prevent conversion to total hip replacement (THR), yet many studies are single institution cohorts, with little generalizability. Purpose The purpose of this study was to perform a systematic review examining the comparative effectiveness of FVFF to treat ONFHN, particularly preventing conversion to a THR and improving hip function/symptoms. Methods We searched PubMed and EMBASE databases using femoral head, free fibula, and femoral neck keywords...
January 16, 2017: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/28089085/the-timing-of-bone-spect-to-predict-osteonecrosis-after-internal-fixation-of-femur-neck-fractures
#19
Ji Wan Kim, Jin-Sook Ryu, Sora Baek, Seong-Eun Byun, Jae Suk Chang
BACKGROUND: Bone SPECT can be used after a femur neck fracture to assess the circulation of the femoral head in the immediate postoperative period because the blood supply is one of the major factors affecting bone uptake of radiotracer on bone scintigraphy. The purpose of our present study was to investigate whether osteonecrosis of the femoral head (OFH) after internal fixation of femoral neck fracture could be predicted by early and late bone SPECT. METHODS: This retrospective cohort study enrolled 44 patients (33 women; mean age, 66...
January 6, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28060181/predicting-periarticular-infection-in-children-with-septic-arthritis-of-the-hip-regionally-derived-criteria-may-not-apply-to-all-populations
#20
Christian A Refakis, Alexandre Arkader, Keith D Baldwin, David A Spiegel, Wudbhav N Sankar
BACKGROUND: The management of septic arthritis of the hip in children can be complicated by the presence of additional coexisting periarticular infections (PAIs). Criteria predicting the presence of PAI have recently been proposed by Rosenfeld and colleagues with the goal of using magnetic resonance imaging (MRI) efficiently in the workup of septic arthritis. The purpose of this study was to determine the applicability of recently published predictive criteria for PAI (developed in the Southwestern United States using a variety of joints) to septic arthritis of the hip treated at a large Northeastern tertiary care center...
January 5, 2017: Journal of Pediatric Orthopedics
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