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https://www.readbyqxmd.com/read/27923216/efficacy-of-a-cellular-bone-allograft-for-foot-and-ankle-arthrodesis-and-revision-nonunion-procedures
#1
Travis J Dekker, Peter White, Samuel B Adams
BACKGROUND: Bone graft substitutes are often required in patients at risk for nonunion, and therefore, an allograft that most closely mimics an autograft is highly sought after. This study explored the utility and efficacy of a cellular bone allograft used for foot and ankle arthrodesis and revision nonunion procedures in a patient population at risk for nonunion. METHODS: An institutional review board-approved retrospective review of consecutive patients who underwent arthrodesis and revision nonunion procedures with a cellular bone allograft was performed at a single academic institution...
October 23, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27919199/predictive-factors-associated-with-the-progression-of-large-joint-destruction-in-patients-with-rheumatoid-arthritis-after-biologic-therapy-a-post-hoc-analysis-using-fdg-pet-ct-and-the-arashi-assessment-of-rheumatoid-arthritis-by-scoring-of-large-joint-destruction
#2
Takahito Suto, Yukio Yonemoto, Koichi Okamura, Chisa Okura, Tetsuya Kaneko, Tsutomu Kobayashi, Masahiro Tachibana, Yoshito Tsushima, Kenji Takagishi
OBJECTIVE: To investigate the associations between large joint damage and findings on fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) using the "assessment of rheumatoid arthritis by scoring of large joint destruction and healing in radiographic imaging (ARASHI)" scoring system. METHODS: A total of 270 large joints (shoulders, elbows, hips, knees, and ankles) in 27 rheumatoid arthritis patients were assessed. FDG-PET/CT was performed at the initiation of biologics...
December 6, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27908492/fragility-fractures-of-the-ankle-in-the-elderly-open-reduction-and-internal-fixation-versus-tibio-talo-calcaneal-nailing-short-term-results-of-a-prospective-randomized-controlled-study
#3
D Georgiannos, V Lampridis, I Bisbinas
INTRODUCTION: The management of ankle fractures in the elderly remains unpredictable, secondary to their various co-morbidities. Although tibiotalocalcaneal (TTC) nailing has been an effective option for ankle arthrodesis due to ankle arthritis or Charcot arthropathy there are few reports regarding the use of TTC nail for the treatment of ankle fractures. PURPOSE: Aim of this study was to compare the results of ORIF versus TTC nailing for the treatment of unstable ankle fractures in the elderly...
November 17, 2016: Injury
https://www.readbyqxmd.com/read/27904705/paclitaxel-suppresses-collagen-induced-arthritis-a-reevaluation
#4
Yi Zhao, Zhi-Fang Chang, Ru Li, Zhan-Guo Li, Xiao-Xia Li, Lin Li
OBJECTIVE: To reevaluate the suppressive effect of paclitaxel (PTX) liposome on collagen-induced arthritis (CIA) in rats and explore its mechanisms. METHODS: Female Lewis rats were immunized with bovine type II collagen (CII) to induce arthritis. The rats with CIA were randomly divided into three groups: 5% GS control group, 2.5 mg/kg PTX treatment group and 1 mg/kg methotrexate (MTX) positive control group. The drugs were administered by intraperitoneal injection on the second day after arthritis onset...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27904594/relationship-between-articular-and-nonarticular-manifestations-in-inflammatory-bowel-diseases
#5
Alimohammad Fatemi, Hourossadat Hashemi Jazi, Mohammad Hasan Emami, Amir Kazemizadeh, Hamid Tavakkoli, Abbas Smiley
BACKGROUND: Musculoskeletal manifestations (MSM) of inflammatory bowel diseases (IBDs) are usually the most frequent extraintestinal manifestations. However, they are not paid enough attention during regular office visits. This cross-sectional study aimed to draw a clinical picture of MSM and their relationships with other findings in patients with IBD. MATERIALS AND METHODS: Patients of our IBD cohort between March 2012 and September 2013 were consecutively evaluated...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27903299/arthroscopic-arthrodesis-for-ankle-arthritis-without-bone-graft
#6
Xiaojun Duan, Liu Yang, Li Yin
BACKGROUND: Ankle arthrodesis is considered by many to be the standard operative treatment for end-stage ankle arthritis. The purpose of this study was to perform a new technique for ankle joint surface and determine the outcome for the union rates of ankle arthroscopic arthrodesis. METHODS: A total of 68 patients with posttraumatic arthritis, primary osteoarthritis, and rheumatoid arthritis were treated by ankle arthroscopic arthrodesis between May 2007 and December 2012...
December 1, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27900440/role-of-methotrexate-chronotherapy-in-collagen-induced-rheumatoid-arthritis-in%C3%A2-rats
#7
X Wang, X Yan, F Wang, F Ge, Z Li
AIM: To explore the circadian rhythm of serum interleukin (IL)-6 in collagen-induced arthritis (CIA) rats and compare the safety and effectiveness of methotrexate (MTX) administered traditionally and via chronotherapy. METHODS: CIA rat models were immunized with bovine type II collagen. Serum IL-6 levels in normal and CIA rats were measured at 2, 6, 10, 14, 18, or 22 h after the light was turned on (HALO). MTX was administered to 6 HALO/18 HALO experimental groups of Wistar rats once daily according to the IL-6 rhythm...
November 29, 2016: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/27900266/ankle-arthrodesis-a-systematic-approach-and-review-of-the-literature
#8
REVIEW
Youichi Yasui, Charles P Hannon, Dexter Seow, John G Kennedy
Ankle arthrodesis is a common treatment used for patients with end-stage ankle arthritis (ESAA). The surgical goal of ankle arthrodesis is to obtain bony union between the tibia and talus with adequate alignment [slight valgus (0°-5°)], neutral dorsiflexion, and slight external rotation positions) in order to provide a pain-free plantigrade foot for weightbearing activities. There are many variations in operative technique including deferring approaches (open or arthroscopic) and differing fixation methods (internal or external fixation)...
November 18, 2016: World Journal of Orthopedics
https://www.readbyqxmd.com/read/27888847/mr-imaging-of-the-diabetic-foot
#9
REVIEW
Eoghan McCarthy, William B Morrison, Adam C Zoga
Abnormalities of the peripheral nervous, vascular, and immune systems contribute to the development of numerous foot and ankle pathologies in the diabetic population. Although radiographs remain the most practical first-line imaging tool, magnetic resonance (MR) is the tertiary imaging modality of choice, allowing for optimal assessment of bone and soft tissue abnormalities. MR allows for the accurate distinction between osteomyelitis/septic arthritis and neuropathic osteoarthropathy. Furthermore, it provides an excellent presurgical anatomic road map of involved tissues and devitalized skin to ensure successful limited amputations when required...
February 2017: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/27886683/complications-of-pediatric-foot-and-ankle-fractures
#10
REVIEW
Jaime R Denning
Ankle fractures account for 5% and foot fractures account for approximately 8% of fractures in children. Some complications are evident early in the treatment or natural history of foot and ankle fractures. Other complications do not become apparent until weeks, months, or years after the original fracture. The incidence of long-term sequelae like posttraumatic arthritis from childhood foot and ankle fractures is poorly studied because decades or lifelong follow-up has frequently not been accomplished. This article discusses a variety of complications associated with foot and ankle fractures in children or the treatment of these injuries...
January 2017: Orthopedic Clinics of North America
https://www.readbyqxmd.com/read/27872167/the-use-of-osteotomies-in-the-treatment-of-asymmetric-ankle-joint-arthritis
#11
REVIEW
Markus Knupp
No abstract text is available yet for this article.
November 20, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27871417/large-bm-intra-articular-allograft
#12
REVIEW
Joan R Williams, Michael E Brage
Posttraumatic tibiotalar arthritis is a challenging problem in young, active patients. Many of these patients do not want to pursue ankle arthrodesis after they fail conservative treatment measures, as they wish to preserve joint motion. Osteochondral shell allograft arthroplasty has been described as a reasonable alternative for treating these patients. The procedure itself is technically demanding; however, with improvements in surgical technique and adequate preoperative patient counseling, it provides improvement in ankle function and has good outcomes for most patients at long-term follow-up...
December 2016: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/27865316/soft-tissue-reconstruction-pyramid-for-the-diabetic-charcot-foot
#13
REVIEW
Claire M Capobianco, Thomas Zgonis
Foot and ankle ulcerations in patients with diabetic Charcot neuroarthropathy (DCN) occur frequently and can be challenging to address surgically when conservative care fails. Patients with acute or chronic diabetic foot ulcers (DFU) are at continued risk for development of osteomyelitis, septic arthritis, gas gangrene, and potential lower extremity amputation. Concurrent vasculopathy and peripheral neuropathy as well as uncontrolled medical comorbidities complicate the treatment approach. In addition, pathomechanical forces left untreated may contribute to DFU recurrence in this patient population...
January 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/27860135/joint-lavage-followed-by-viscosupplementation-and-triamcinolone-in-patients-with-severe-haemophilic-arthropathy-objective-functional-results
#14
M U Rezende, F R Andrusaitis, R T Silva, E Okazaki, J D A Carneiro, G C Campos, A F Pailo, R Frucchi, T Pasqualin, P R Villaça
INTRODUCTION: Viscosupplementation can improve function in haemophilia patients. Viscosupplementation results can be improved by prior joint lavage and triamcinolone administration. AIM: To objectively assess whether viscosupplementation and associated triamcinolone use in patients with severe haemophilic arthropathy following joint lavage improves force and balance and reduces bleeding events. METHODS: Fourteen patients with haemophilic knee arthritis with and without the involvement of other joints underwent joint lavage and subsequent injections of Hylan G-F20 and triamcinolone into all affected joints...
November 16, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27857500/inter-observer-variability-and-its-correlation-to-experience-in-measurement-of-lower-limb-mechanical-axis-on-long-leg-radiographs
#15
Raju Vaishya, Vipul Vijay, Vikas P Birla, Amit Kumar Agarwal
INTRODUCTION: Restoration of mechanical axis (MA) is one of the most important aims of treatment of knee arthritis. The measurement of MA is often done on hip knee ankle (HKA) radiographs (LLR), but its measurement is often difficult and variable. We studied to check if inter-observer variability in the measurement of MA is dependent on the experience of the observer. MATERIALS AND METHODS: 48 patients (70 knees) underwent measurement of MA on HKA radiographs. The measurement was done by five observers of different experience...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/27852383/-surgery-of-ipsilateral-hawkins-%C3%A2-talus-neck-and-ankle-joint-fractures-via-internal-and-lateral-approaches-with-herbert-screws
#16
P Zhang, Q R Dong, Z Y Wang, B Chen, J H Wan, L Wang
Objective: To explore the manual operation skills of operative treatment of ipsilateral Hawkins Ⅲ talus neck and ankle joint fractures via internal and lateral approaches with Herbert screws, and to study the clinical results. Method: From Jan 2009 to Dec 2014, the clinical data of 13 patients with ipsilateral Hawkins Ⅲ talus neck and ankle joint fractres via internal and lateral approaches with Herbert screws were retrospectively analyzed in our department.There were 10 males and 3 female, ranging in age from 20 to 60 years with an average age of 31...
November 8, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27851983/osteopontin-inhibition-of-mir-129-3p-enhances-il-17-expression-and-monocyte-migration-in-rheumatoid-arthritis
#17
Chun-Hao Tsai, Shan-Chi Liu, Yu-Han Wang, Chen-Ming Su, Chien-Chung Huang, Chin-Jung Hsu, Chih-Hsin Tang
BACKGROUND: Osteopontin (OPN) is an important proinflammatory cytokine in rheumatoid arthritis (RA). Levels of OPN have been shown to be significantly correlated with interleukin-17 (IL-17) production and expression of Th17 cells in the synovial fluid of RA patients. Here, we investigated the role of OPN in monocyte migration, IL-17 production and osteoblasts. METHODS: OPN and IL-17 expression profiles in osteoarthritis (OA) and RA synovial fluid were determined by enzyme-linked immunosorbent assay (ELISA)...
November 13, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27846748/beneficial-effects-of-natural-eggshell-membrane-nem-on-multiple-indices-of-arthritis-in-collagen-induced-arthritic-rats
#18
Karen J Wedekind, Kevin J Ruff, Cindy A Atwell, Joseph L Evans, Alison M Bendele
OBJECTIVES: This study was performed to evaluate the potential efficacy of natural eggshell membrane (NEM) in collagen-induced arthritic rats, a well-established rodent model of inflammation and rheumatoid arthritis. METHODS: Rats with developing type II collagen-induced arthritis (CIA) were treated once daily by oral gavage on study days -14 to 17 with vehicle or NEM (52 mg/kg body weight). Rats were euthanized on study day 17. Efficacy was assessed by daily ankle caliper measurements, ankle diameter expressed as area under the curve (AUCd0-17), and histopathologic evaluation of ankles and knees...
November 16, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27830485/lateral-compartment-osteophytes-are-not-associated-with-lateral-compartment-cartilage-degeneration-in-arthritic-varus-knees
#19
Wenzel Waldstein, Maximilian F Kasparek, Martin Faschingbauer, Reinhard Windhager, Friedrich Boettner
BACKGROUND: Progression of arthritis in the lateral compartment is one of the main failure modes of unicompartmental knee arthroplasty (UKA). The decision regarding whether to perform a medial UKA sometimes is made based on whether lateral-compartment osteophytes are visible on plain radiographs obtained before surgery, but it is not clear whether the presence of lateral-compartment osteophytes signifies that the cartilage in the lateral compartment is arthritic. QUESTIONS/PURPOSES: (1) Is the presence of lateral compartment osteophytes associated with biomechanical properties of lateral-compartment cartilage, and (2) are osteophytes in the lateral compartment associated with particular histologic features of cartilage in the lateral compartment? METHODS: Between May 2010 and January 2012, we performed 201 TKAs for varus osteoarthritis confirmed on standardized AP hip-to-ankle standing radiographs...
November 9, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27824657/effect-of-footwear-on-joint-pain-and-function-in-older-adults-with-lower-extremity-osteoarthritis
#20
Amy Wagner, Sarah Luna
BACKGROUND AND PURPOSE: Lower extremity osteoarthritis (OA) is a common condition among older adults; given the risks of surgical and pharmaceutical interventions, conservative, lower-cost management options such as footwear warrant further investigation. This systematic review investigated the effects of footwear, including shoe inserts, in reducing lower extremity joint pain and improving gait, mobility, and quality of life in older adults with OA. METHODS: The CINAHL, SPORTDiscus, PubMed, RECAL, and Web of Knowledge databases were searched for publications from January 1990 to September 2014, using the terms "footwear," "shoes," "gait," "pain," and "older adult...
November 7, 2016: Journal of Geriatric Physical Therapy
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