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https://www.readbyqxmd.com/read/29457399/-osseous-bridge-resection-for-the-treatment-of-adult-talocalaneal-coalitions-without-arthritis
#1
Bing Xie, Shuo Yan, Hao Zhang, Yuan-Wei Wang, Jing Tian
OBJECTIVE: To analyze clinical outcomes of osseous-bridge resection for the treatment of adult symptomatic talocalcaneal coalitions without arthritis. METHODS: The clinical data of 12 patients (15 feet) with symptomatic talocalcaneal coalitions without arthtitis from January 2013 to June 2016 were respectively analyzed. All cases were secondary talocalcaneal coalition. There were 9 males (11 feet) and 3 females (4 feet) with a mean (26.6±3.3) years old (ranged, 18 to 33 years old)...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29455511/-treatment-of-gouty-arthritis-of-the-first-metatarsophalangeal-joint-by-masquelet-technique
#2
Cheng-Lin Wang, Jun-Zhong Yang
OBJECTIVE: To study clinical curative effects of a Masquelet technology in the treatment of gouty arthritis in the first metatarsophalangeal joint. METHODS: From February 2012 to May 2016, 7 patients with the gouth arthritis of the first metatarsophalangeal joint were treated by the Masqueket technology. There were 5 males and 2 females, ranging in age from 42 to 58 years old, with an average age of 50 years old. During the regular follow up, the bone healing was assessed by the radiographic imaging, and the orthopaedic foot and ankle Association (AOFAS) ankle function scoring system was used for comprehensive evaluation...
August 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29448824/influence-of-diagnosis-and-other-factors-on-patients-expectations-of-foot-and-ankle-surgery
#3
Elizabeth A Cody, Huong T Do, Jayme C B Koltsov, Carol A Mancuso, Scott J Ellis
BACKGROUND: Many patient factors have been associated with higher or lower expectations of orthopaedic surgery. In foot and ankle surgery, the diverse diagnoses seen may also influence expectations. The aim of this study was to investigate the relationship between diagnosis and patients' preoperative expectations of elective foot and ankle surgery. METHODS: Two hundred seventy-eight patients undergoing elective foot or ankle surgery for 1 of 7 common diagnoses were enrolled in a prospective cohort study...
February 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29447303/arthroscopic-anterior-ankle-decompression-is-successful-in-national-football-league-players
#4
Christopher L McCrum, Justin W Arner, Bryson Lesniak, James P Bradley
Anterior ankle impingement is a frequent cause of pain and disability in athletes with impingement of soft-tissue or osseous structures along the anterior margin of the tibiotalar joint during dorsiflexion. In this study, we hypothesized that arthroscopic decompression of anterior ankle impingement would result in significant, reliable, and durable improvement in pain and range of motion (ROM), and would allow National Football League (NFL) players to return to their preoperative level of play. We reviewed 29 arthroscopic ankle débridements performed by a single surgeon...
January 2018: American Journal of Orthopedics
https://www.readbyqxmd.com/read/29427441/the-utility-of-the-ankle-spect-ct-scan-to-predict-functional-and-clinical-outcomes-in-supramalleolar-osteotomy-patients
#5
Christopher E Gross, William Barfield, Christine Schweizer, Helmut Rasch, Michael T Hirschmann, Beat Hintermann, Markus Knupp
Combined single-photon emission computed tomography and conventional computed tomography (SPECT/CT) is a hybrid imaging modality that shows a combination of metabolic and structural information about the ankle, including arthritis. We hypothesize that uptake in specific locations within the ankle joint can be associated with both clinical outcomes and may help predict which patients will have a successful SMO. Eighty-five pre-operative SMO patients with varus (37), valgus (41), or neutral (7) alignment of the hindfoot were assessed using SPECT/CT...
February 10, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29424171/-retrograde-interlocked-intramedullary-nailing-with-tibia-bone-graft-fusion-for-the-treatment-of-end-stage-ankle-arthritis
#6
Zhong-Yu Hao, Ping Pei, Lin Liu, Yu-Xin Song
OBJECTIVE: To explore clinical outcomes of retrograde interlocked intramedullary nailing with tibia bone graft fusion in treating end-stage ankle arthritis. METHODS: From November 2014 to April 2016, 22 patients with end-stage ankle arthritis were treated with retrograde interlocked intramedullary nailing with tibia bone graft fusion, including 9 males and 13 females aged from 30 to 65 years old with an average of 48.5 years old. Seven patients had obvious varus deformity, and other 15 patients' appearance were normal...
June 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29422084/anti-cd11b-antibody-treatment-suppresses-the-osteoclast-generation-inflammatory-cell-infiltration-and-autoantibody-production-in-arthritis-prone-fc%C3%AE-riib-deficient-mice
#7
Mareki Ohtsuji, Qingshun Lin, Hideki Okazaki, Kazuko Takahashi, Hirofumi Amano, Hideo Yagita, Hiroyuki Nishimura, Sachiko Hirose
BACKGROUND: Previously we established an arthritis-prone FcγRIIB-deficient mouse strain (designated KO1). Anti-mouse CD11b mAb (5C6) has been reported to inhibit the recruitment of peripheral CD11b + myelomonocytic cells from the blood to the inflammatory site. These cells include neutrophils and monocytes, both of which play important roles in the development of arthritis. Here we treated KO1 mice with 5C6 mAb in order to study its effect on arthritis development. METHODS: To evaluate the disease-preventive effect of 5C6, 4-month-old preclinical KO1 mice were divided into three groups: the first treated with 5C6 for 6 months, the second treated with normal rat IgG for 6 months, as a control, and the third left untreated...
February 8, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29422077/adiponectin-aggravates-bone-erosion-by-promoting-osteopontin-production-in-synovial-tissue-of-rheumatoid-arthritis
#8
Jie Qian, Lingxiao Xu, Xiaoxuan Sun, Yani Wang, Wenhua Xuan, Qian Zhang, Pengfei Zhao, Qin Wu, Rui Liu, Nan Che, Fang Wang, Wenfeng Tan, Miaojia Zhang
BACKGROUND: We have previously reported that adiponectin (AD), an adipokine that is secreted by adipocytes, correlates well with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD in promoting joint destruction remains unclear. Osteopontin (OPN) is required for osteoclast recruitment. We hypothesized that AD exacerbates bone erosion by inducing OPN expression in synovial tissue. This study aimed to evaluate a novel role for AD in RA. METHODS: The serum levels of AD and OPN were determined in 38 patients with RA, 40 patients with osteoarthritis (OA), and 20 healthy controls using enzyme-linked immunosorbent assay (ELISA)...
February 8, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29417781/-surgical-treatment-for-talar-neck-fracture-of-hawkins-iii-iv-type-with-compression-hollow-screws-combined-with-external-fixator
#9
Xian-Xun Wang, Chang-Tao Wan, Li Yu
OBJECTIVE: To investigate the clinical effects of compression hollow screws combined with external fixator in treating talar neck fracture of Hawkins III, IV type. METHODS: From March 2010 to August 2014, 15 patients with talar neck fractures of Hawkins III, IV type were treated by open reduction and compression hollow screws fixation complicated with external fixator fixation. Including 9 males and 6 females, aged from 17 to 65 years old with an average of 37.5 years old...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29409277/the-current-standard-of-foot-and-ankle-fellowship-in-the-uk
#10
R Brown, P Akimau, J Hsuan, T Williams
BACKGROUND: The aim of this study was to evaluate the current standards of Fellowship training in Foot and Ankle Surgery Fellowship in the UK. METHODS: Thirteen UK post-FRCS (Tr&Orth) or equivalent Fellows completed a questionnaire detailing their outpatient, surgical, teaching and research experience, along with documenting their supervision and terms of employment. RESULTS: A Fellow attended a mean of 2.5 (0.5-4) clinics and 3.84 (2-7) theatre sessions per week...
June 10, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409205/clinical-characteristics-and-surgical-experience-of-type-iii-wagstaffe-fractures-pay-attention-to-concomitant-chondral-injury-of-the-talus
#11
Ming Zhang, Yun-Feng Chen, Lei Wang, Fan Li, Hai-Feng Wei, Zhong-Min Shi
BACKGROUND: The purpose of this study was to investigate clinical characteristics and surgical management of Type III Wagstaffe fracture. METHODS: From August 2012 to July 2015, 13 patients with Type III Wagstaffe fractures were surgically treated. During operation, the cartilage of joint surface was explored. Wagstaffe fragment was fixed with cannulated screw or suture, Chaput fragment was fixed with cannulated screw or plate, and Cotton test was performed to evaluate the stability of syndesmosis during the operation...
April 27, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409199/treatment-of-first-metatarsophalangeal-joint-arthritis-using-hemiarthroplasty-with-a-synthetic-cartilage-implant-or-arthrodesis-a-comparison-of-operative-and-recovery-time
#12
Mark Glazebrook, Alastair S E Younger, Timothy R Daniels, Dishan Singh, Chris Blundell, Gwyneth de Vries, Ian L D Le, Dominic Nielsen, M Elizabeth Pedersen, Anthony Sakellariou, Matthew Solan, Guy Wansbrough, Judith F Baumhauer
BACKGROUND: First metatarsophalangeal joint (MTPJ1) hemiarthroplasty using a novel synthetic cartilage implant was as effective and safe as MTPJ1 arthrodesis in a randomized clinical trial. We retrospectively evaluated operative time and recovery period for implant hemiarthroplasty (n=152) and MTPJ1 arthrodesis (n=50). METHODS: Perioperative data were assessed for operative and anaesthesia times. Recovery and return to function were prospectively assessed with the Foot and Ankle Ability Measure (FAAM) Sports and Activities of Daily Living (ADL) subscales and SF-36 Physical Functioning (PF) subscore...
May 29, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409171/comparing-30-day-all-cause-readmission-rates-between-tibiotalar-fusion-and-total-ankle-replacement
#13
Robert K Merrill, Rocco M Ferrandino, Ryan Hoffman, Anthony Ndu, Gene W Shaffer
BACKGROUND: End-stage ankle arthritis is a debilitating condition that negatively impacts patient quality of life. Tibiotalar fusion and total ankle replacement are treatment options for managing ankle arthritis. Few studies have examined short term readmission rates of these two procedures. The objective of this study was compare all-cause 30-day readmission rates between patients undergoing tibiotalar fusion vs. total ankle replacement. METHODS: This study queried the Nationwide Readmission Database (NRD) from 2013-2014 and used international classification of disease, 9th revision (ICD-9) procedure codes to identify all patients who underwent a tibiotalar fusion or a total ankle replacement...
January 12, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29401630/tetrandrine-attenuates-the-bone-erosion-in-collagen-induced-arthritis-rats-by-inhibiting-osteoclastogenesis-via-spleen-tyrosine-kinase
#14
Yugai Jia, Yumeng Miao, Mengfan Yue, Mei Shu, Zhifeng Wei, Yue Dai
Tetrandrine, a bisbenzylisoquinoline alkaloid, was previously demonstrated to attenuate inflammation and cartilage destruction in the ankles of mice with collagen-induced arthritis (CIA). Here, we explored the underlying mechanism by which tetrandrine prevented arthritis-induced bone erosion by focusing on the differentiation and function of osteoclasts. We found that daily administration of tetrandrine (30 mg/kg) markedly reduced the bone damage and decreased the number of osteoclasts in CIA rats. In vitro, tetrandrine inhibited receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis at the early stage and reduced the expressions of osteoclast-related marker genes...
January 30, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29395553/arthroscopic-ankle-arthrodesis-a-2-15%C3%A2-year-follow-up-study
#15
Christopher Robert Jones, Eric Wong, Gregory R Applegate, Richard D Ferkel
PURPOSE: The purpose of our study was to determine the results of arthroscopic ankle arthrodesis (AAA) and how the procedure affects adjoining joints and functional scores. METHODS: Between 1993 and 2013, 116 patients (120 ankles) underwent AAA. Nineteen ankles were lost to follow-up due to death, insufficient radiographic studies, or inability to contact, resulting in 97 patients (101 ankles). Mean age at surgery was 61.1 years (range, 35.8-79.6 years); mean follow-up was 86 months (range, 24-247 months)...
January 25, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29389250/scandinavian-total-ankle-replacement-15-year-follow-up
#16
Ariel Palanca, Roger A Mann, Jeffrey A Mann, Andrew Haskell
BACKGROUND: Over the past decade, total ankle arthroplasty (TAA) has become a mainstay in the treatment of end-stage ankle arthritis. Currently in its fourth generation, the Scandanavian Total Ankle Replacement (STAR) is the only 3-piece mobile bearing ankle prosthesis available in the United States. Our current study reports implant survivorship at 15 years and patient outcomes for a subset of these survivors available for study. METHODS: Eighty-four TAAs were performed between 1998 and 2000...
February 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29382005/successful-treatment-of-pachydermoperiostosis-patients-with-etoricoxib-aescin-and-arthroscopic-synovectomy-two-case-reports
#17
Hengyan Zhang, Bo Yang
RATIONALE: Pachydermoperiostosis (PDP) is a rare hereditary disorder that affects the skin and bones. PDP is characterized by periostosis, digital clubbing, and pachydermia. Previous studies demonstrated that increased prostaglandin E2 (PGE2) levels resulting from defective protein degradation pathways play a crucial role in PDP pathogenesis, and males were more commonly and severely affected than females. Moreover, nearly all PDP patients suffer from refractory arthralgia. Although several different treatment modalities are used for PDP, therapy for this disease remains challenging...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29381085/gum-acacia-stabilized-silver-nanoparticles-based-nano-cargo-for-enhanced-anti-arthritic-potentials-of-hesperidin-in-adjuvant-induced-arthritic-rats
#18
Komal Rao, Sabahat Aziz, Talat Roome, Anam Razzak, Bushra Sikandar, Khawar Saeed Jamali, Muhammad Imran, Tooba Jabri, Muhammad Raza Shah
Nanomedicines anticipate drug delivery to inflamed tissues in rheumatoid arthritis (RA) with greater efficacy and lesser side effects. This study investigates the anti-arthritic potentials of Hesperidin (HP) loaded in gum acacia (GA) stabilized green silver nanoparticles (AgNPs). Synthesized GA-AgNPs were characterized through UV-vis spectrophotometer, zetasizer and atomic force microscope (AFM). The HP and its loaded NPs were tested for RA in Complete Freund's adjuvant (CFA) induced arthritis model. GA-AgNPs were found in nano-range size with negative charge, spherical shape and loaded increased HP amount...
January 30, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29380927/increased-hyperpolarized-1-13-c-lactate-production-in-a-model-of-joint-inflammation-is-not-accompanied-by-tissue-acidosis-as-assessed-using-hyperpolarized-13-c-labelled-bicarbonate
#19
Alan J Wright, Zoé M A Husson, De-En Hu, Gerard Callejo, Kevin M Brindle, Ewan St John Smith
Arthritic conditions are a major source of chronic pain. Furthering our understanding of disease mechanisms creates the opportunity to develop more targeted therapeutics. In rheumatoid arthritis (RA), measurements of pH in human synovial fluid suggest that acidosis occurs, but that this is highly variable between individuals. Here we sought to determine if tissue acidosis occurs in a widely used rodent arthritis model: complete Freund's adjuvant (CFA)-induced inflammation. CFA robustly evoked paw and ankle swelling, concomitant with worsening clinical scores over time...
January 30, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29366342/long-term-follow-up-of-revision-osteochondral-allograft-transplantation-of-the-ankle
#20
Florian Gaul, Luís E P Tírico, Julie C McCauley, William D Bugbee
BACKGROUND: Osteochondral allograft (OCA) transplantation is a useful alternative for treatment of posttraumatic ankle arthritis in young patients but has a relatively high failure rate and further procedures are often required. The purpose of this study was to evaluate outcomes of patients who underwent revision OCA transplantation of the ankle after failed primary OCA transplantation. METHODS: Twenty patients underwent revision OCA transplantation of the ankle between 1988 and 2015...
January 1, 2018: Foot & Ankle International
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