keyword
MENU ▼
Read by QxMD icon Read
search

xerosis

keyword
https://www.readbyqxmd.com/read/28214613/the-effectiveness-of-standardized-skin-care-regimens-on-skin-dryness-in-nursing-home-residents-a-randomized-controlled-parallel-group-pragmatic-trial
#1
Elisabeth Hahnel, Ulrike Blume-Peytavi, Carina Trojahn, Gabor Dobos, Andrea Stroux, Natalie Garcia Bartels, Irina Jahnke, Andrea Lichterfeld-Kottner, Heike Neels-Herzmann, Anja Klasen, Jan Kottner
BACKGROUND: Aged residents of institutional long-term care facilities are at high risk for developing skin and tissue diseases. Besides various common skin problems, dry skin (xerosis cutis) is one of the most frequent skin conditions in this setting. OBJECTIVES: To investigate the effectiveness of two structured skin care regimens in comparison to routine skin care on xerosis cutis in nursing home residents. DESIGN: A multi-center, pragmatic, randomized, controlled, investigator blinded study with three parallel groups...
February 7, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28205205/regression-of-cutaneous-xerosis-with-emollient-treatment-in-sub-saharan-african-patients
#2
Franck Boralevi, Alain-Patrice Meledie N'Djong, Pauline Yao Yoboue, Ousmane Faye, Mame Thierno Dieng, Sophie Coniquet, Félix Atadokpede, Pascal Antoine Niamba, Alain Delarue, Christine Cazeau
Emollients have proven effective in improving cutaneous xerosis in various populations; however, no clinical data are available for African patients. The observational study "Xerafrica" was conducted by dermatologists in seven sub-Saharan countries to assess the evolution of xerosis after an 8-week treatment with an emollient. Patients were children above 3 years or adults. Secondary objectives were to assess pruritus, improvement in symptoms, quality of life, satisfaction, and tolerance. An analysis of 185 patients was made...
February 16, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28196317/common-skin-conditions-in-children-noninfectious-rashes
#3
Brian Z Rayala, Dean S Morrell
Cutaneous adverse drug reactions are among the most common noninfectious rashes of childhood. Cutaneous adverse drug reactions are classified as morbilliform, urticarial, bullous, pustular, or psoriasiform. Atopic dermatitis is one of the most common inflammatory cutaneous eruptions, and is characterized by pruritus and flexural distribution. Emollients and topical corticosteroids are first-line therapies. Topical calcineurin inhibitors are second-line, steroid-sparing drugs for certain conditions, such as face and eyelid eczema...
February 2017: FP Essentials
https://www.readbyqxmd.com/read/28191040/moisturisers-for-the-treatment-of-foot-xerosis-a-systematic-review
#4
REVIEW
Justin Parker, Rolf Scharfbillig, Sara Jones
BACKGROUND: Xerosis, literally dryness of the skin, of the foot is a common condition encountered clinically, which can lead to discomfort and predisposition to infection. Currently, there are no evidence-based recommendations on which moisturiser formulations best alleviate xerotic symptoms. The aim of this review was to guide clinical practice in the treatment of primary and diabetes related foot xerosis, by identifying from the existing literature the most effective ingredient or formulation of topical treatments for symptoms of primary foot xerosis in the general population...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28131849/characterization-and-biocompatibility-evaluation-of-cutaneous-formulations-containing-lipid-nanoparticles
#5
F Eiras, M H Amaral, R Silva, E Martins, J M Sousa Lobo, A C Silva
Nanostructured lipid carriers (NLC) are well-known systems that show effectiveness to improve skin hydration, being suggested for cosmetic and dermatological use. Nonetheless, NLC dispersions present low viscosity, which is non-attractive for cutaneous application. To circumvent this drawback, the dispersions can be gelled or incorporated in semisolid systems, increasing the final formulation consistency. In this study, we prepared a hydrogel based on NLC containing vitamin E (HG-NLCVE) and evaluated its suitability for cutaneous application...
January 25, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28120350/efficacy-of-a-rhealba-%C3%A2-oat-extract-based-emollient-on-chronic-pruritus-in-elderly-french-outpatients
#6
J Theunis, H Chaussade, O Bourgeois, V Mengeaud
BACKGROUND: Chronic pruritus, defined as itch persisting more than 6 weeks, is a debilitating problem that affects one in four elderly adults. Emollients are recommended for the management of pruritus, but evidence of efficacy is scarce. OBJECTIVE: Assess the efficacy of a Rhealba(®) Oat Extract-based emollient in the management of chronic pruritus in elderly outpatients. METHODS: This was a randomized, mono-centric, open-label, cross-over study in adults ≥60 years of age with xerosis associated with chronic pruritus...
February 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28112767/nutritional-status-and-habitual-dietary-intake-are-associated-with-frail-skin-conditions-in-community-dwelling-older-people
#7
S Iizaka, S Nagata, H Sanada
OBJECTIVE: Prevention of frail skin is important in older people because frail skin is associated with a risk of injury in this population. In this study, we investigated the association of nutritional status and habitual dietary intake with skin conditions in community-dwelling older people. DESIGN: Cross-sectional study. SETTING: Three community settings in Japan from autumn to winter. PARTICIPANTS: Older people aged ≥65 years without care-need certification (n=118)...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28095570/efficacy-of-a-skin-condition-adapted-solution-for-xerosis-and-itch-relief-associated-with-aging
#8
Ramsin Joseph Yadgar, Adam J Friedman
In recent decades, the stratum corneum (SC), has been recognized for its multifunctional role in maintaining the homeostasis of the human epidermal barrier. A better understanding of the SC's ability to act as its own biosensor in detecting dysfunction and integrating restorative actions can help identify the origin of certain skin conditions. A more holistic understanding of the morphological changes of the SC during the natural aging process and how it deviates in disease states can help bring about new treatment strategies...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28078772/skin-cleansing-and-emolliating-for-older-people-a-quasi-experimental-pilot-study
#9
Jill Brooks, Fiona Cowdell, Steven J Ersser, Eric D Gardiner
AIMS: The aims of this study were to (i) assess the effect of low-cost hygiene and emollient regimens on the skin barrier function (SBF) of people aged >65 year with xerosis (dry skin) on their lower legs; (ii) to assess the utility of portable measures of skin barrier function in terms of stratum corneum hydration (SCH) and transepidermal water loss (TEWL) in community settings; and iii) to provide evidence for a randomised controlled trial on the treatment of adults in a resource-poor country with dry skin on their lower legs which causes and exacerbates the skin disease podoconiosis (non-filarial elephantiasis)...
January 12, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/28065683/cutaneous-features-of-myotonic-dystrophy-types-1-and-2-implication-of-premature-aging-and-vitamin-d-homeostasis
#10
Elena Campione, Annalisa Botta, Monia Di Prete, Emanuele Rastelli, Manuela Gibellini, Antonio Petrucci, Sergio Bernardini, Giuseppe Novelli, Luca Bianchi, Augusto Orlandi, Roberto Massa, Chiara Terracciano
Skin changes have been described in myotonic dystrophy type 1 (DM1). However, whether and in which way skin is a target of specific disease alterations in DM1 and DM2 has not been yet clarified. This study aims to explore cutaneous features of DM1 and DM2 patients. Skin examination was performed in 60 DM1, 15 DM2, and 103 control, unselected patients by means of dermoscopy. It revealed quantitative and qualitative abnormalities of nevi and typical signs of premature aging in both DM1 and DM2 patients, with a significantly higher frequency of dysplastic nevi, alopecia, xerosis and seborrheic dermatitis...
November 16, 2016: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28004308/cutaneous-side-effects-and-transepidermal-water-loss-to-gefitinib-a-study-of-11-patients
#11
Franky Chandra, Dendi Sandiono, Unwati Sugiri, Oki Suwarsa, Hendra Gunawan
INTRODUCTION: Cutaneous side effects caused by epidermal growth factor receptor (EGFR) inhibitors occurred in 45-100% of patients which may lead to therapy modification or interruption. This study aimed to evaluate cutaneous side effects and transepidermal water loss (TEWL) values in non-small cell lung carcinoma (NSCLC) patients who received gefitinib EGFR inhibitor. METHODS: A descriptive observational study with cross-sectional design and a consecutive sampling method was conducted from 1 February to 4 March 2016...
December 21, 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/28003921/bullous-dermatosis-in-an-end-stage-renal-disease-patient-a-case-report-and-literature-review
#12
Zeenat Yousuf Bhat, Marwan Abu Minshar, Nashat Imran, Andrew Thompson, Yahya Osman Malik
Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis...
2016: Case Reports in Nephrology
https://www.readbyqxmd.com/read/27997725/efficacy-of-an-emollient-cream-in-the-treatment-of-xerosis-in-diabetic-foot-a-double-blind-randomized-vehicle-controlled-clinical-trial
#13
J Martini, C Huertas, V Turlier, C Saint-Martory, A Delarue
BACKGROUND: Peripheral neuronal impairment compromises foot health in diabetic patients. Clinically, xerosis is the most common mild complication, but it should not be underestimated. An effective treatment must be able to restore the cutaneous barrier and prevent water loss, to maintain adequate hydration and protection. OBJECTIVE: This study aimed to assess the efficacy of an emollient cream on foot xerosis in diabetic patients. METHODS: This is a prospective, multicenter, randomized, double-blind contralateral vehicle-controlled study in 57 diabetic patients...
December 20, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27984271/effects-of-colloidal-oatmeal-lotion-on-symptoms-of-dermatologic-toxicities-induced-by-epidermal-growth-factor-receptor-inhibitors
#14
Ya-Ting Ke, Chia-Chi Kuo
OBJECTIVE: The common adverse effects associated with targeted therapy for cancer, such as epidermal growth factor receptor inhibitors (EGFRIs), are dermatologic toxicities that cause the patient physical discomfort and affect treatment. Colloidal oatmeal lotion (COL) has been proven to help prevent dermatitis and xerosis. Evidence of its effect on EGFRI-induced dermatologic toxicities, however, is limited. The purpose of this study was to explore the effect of COL on EGFRI-induced dermatologic toxicities...
January 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/27911432/-eye-lid-hygiene-in-chronic-allergic-blepharoconjunctivitis-patients-before-laser-refractive-surgery
#15
S V Yanchenko, A V Malyshev, S N Sakhnov, N V Fedotova, O Yu Orekhova
AIM: To evaluate the effectiveness of eyelid hygiene in patients with chronic allergic blepharoconjunctivitis (ABC) as a part of their preparation for laser refractive surgery. MATERIAL AND METHODS: The study involved 32 patients (12 males and 20 females aged 25-42 years) with refractive errors, namely, compound myopic astigmatism (23 patients) and hyperopic astigmatism (9 patients) suffering from chronic ABC and secondary dry eye syndrome (DES). All the patients initially received a standard treatment for ABC and DES, that is olopatodin hydrochloride instillations - 1 mg/ml 2 times daily, preservative-free hyaluronic acid preparation - 1 mg/ml 3 times daily, and polyacrylic acid and dexpanthenol gel at night for one month...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27879948/efficacy-and-local-tolerability-of-different-spray-products-in-the-treatment-of-mild-to-moderate-acne-of-the-back-and-chest-a-controlled-3-arm-assessor-blinded-prospective-trial
#16
Ada Lo Schiavo, Rosa V Puca, Francesca Romano, Massimo Milani
BACKGROUND: A spray formulation containing 2 vitamin-A derivatives (hydroxypinacolone retinoate and retinol) carried in glycospheres (RetinSphere®) combined with an antimicrobial peptide (BIOPEP-15), salicylic acid and vitamin E (BR) has been recently developed for the treatment of truncal acne. We evaluated clinical efficacy of BR in comparison with two commonly used sprays, containing triethylcitrate and ethylinoleate (AK) and containing betaine, glycine and salicylic acid 2% (SP)...
November 23, 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27875703/prevalence-and-characterization-of-neonatal-skin-disorders-in-the-first-72h-of-life
#17
Flávia Pereira Reginatto, Damie DeVilla, Fernanda M Muller, Juliano Peruzzo, Letícia P Peres, Raquel B Steglich, Tania F Cestari
OBJECTIVE: To determine the prevalence of neonatal dermatological findings and analyze whether there is an association between these findings and neonatal and pregnancy characteristics and seasonality. METHODS: Newborns from three maternity hospitals in a Brazilian capital city were randomly selected to undergo dermatological assessment by dermatologists. RESULTS: 2938 neonates aged up to three days of life were randomly selected, of whom 309 were excluded due to Intensive Care Unit admission...
November 19, 2016: Jornal de Pediatria
https://www.readbyqxmd.com/read/27871086/the-influence-of-two-different-foam-creams-on-skin-barrier-repair-of-foot-xerosis-a-prospective-double-blind-randomised-placebo-controlled-intra-individual-study
#18
Dorothee Daehnhardt, Stephan Daehnhardt-Pfeiffer, Judith Schulte-Walter, Thomas Neubourg, Eckhard Hanisch, Christel Schmetz, Marion Breuer, Regina Fölster-Holst
BACKGROUND/AIMS: Dry skin, or xerosis, is a common condition and a key feature of skin diseases like atopic dermatitis (AD) and ichthyosis vulgaris. Foot xerosis may exist without underlying disease and could be related to very mild forms of AD or ichthyosis vulgaris. The synthesis of important skin lipids (cholesterol, free fatty acids and ceramides) is reduced in xerosis and AD, and reduced lipid synthesis is responsible for a lack of lipids and enzymes in the skin barrier. This slows down reorganisation of the lipid lamellae in the stratum corneum (SC)...
2016: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/27846299/hyperglycemia-induces-skin-barrier-dysfunctions-with-impairment-of-epidermal-integrity-in-non-wounded-skin-of-type-1-diabetic-mice
#19
Junko Okano, Hideto Kojima, Miwako Katagi, Takahiko Nakagawa, Yuki Nakae, Tomoya Terashima, Takeshi Kurakane, Mamoru Kubota, Hiroshi Maegawa, Jun Udagawa
Diabetes causes skin complications, including xerosis and foot ulcers. Ulcers complicated by infections exacerbate skin conditions, and in severe cases, limb/toe amputations are required to prevent the development of sepsis. Here, we hypothesize that hyperglycemia induces skin barrier dysfunction with alterations of epidermal integrity. The effects of hyperglycemia on the epidermis were examined in streptozotocin-induced diabetic mice with/without insulin therapy. The results showed that dye leakages were prominent, and transepidermal water loss after tape stripping was exacerbated in diabetic mice...
2016: PloS One
https://www.readbyqxmd.com/read/27824277/novel-bioactive-from-lactobacillus-brevis-dsm17250-to-stimulate-the-growth-of-staphylococcus-epidermidis-a-pilot-study
#20
C Holz, J Benning, M Schaudt, A Heilmann, J Schultchen, D Goelling, C Lang
Commensal skin microbiota plays an important role in both influencing the immune response of the skin and acting as a barrier against colonisation of potentially pathogenic microorganisms and overgrowth of opportunistic pathogens. Staphylococcus epidermidis is a key constituent of the normal microbiota on human skin. It balances the inflammatory response after skin injury and produces antimicrobial molecules that selectively inhibit skin pathogens. Here we describe Lactobacillus brevis DSM17250 that was identified among hundreds of Lactobacillus strains to exhibit an anti-inflammatory effect in human keratinocytes in vitro and specific stimulatory impact on the growth of S...
November 8, 2016: Beneficial Microbes
keyword
keyword
79498
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"