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https://www.readbyqxmd.com/read/28284508/geographical-differences-in-thromboembolic-and-bleeding-risks-in-patients-with-non-valvular-atrial-fibrillation-an-ancillary-analysis-from-the-sportif-trials
#1
Marco Proietti, Gregory Yh Lip
BACKGROUND: Atrial fibrillation (AF) is associated with an increased risk of stroke, and the use of oral anticoagulation reduces stroke and all-cause mortality. Geographical differences may exist in AF risk factors, risk stratification and treatment strategies. METHODS: A post-hoc subgroup analysis derived from randomized controlled trials, the SPORTIF III and V trials, studying differences between European and North American warfarin-assigned non-valvular AF patients...
February 27, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28279600/development-of-a-novel-compound-microbial-agent-for-degradation-of-kitchen-waste
#2
Kaining Zhao, Rui Xu, Ying Zhang, Hao Tang, Chuanbin Zhou, Aixin Cao, Guozhu Zhao, Hui Guo
Large quantities of kitchen waste are produced in modern society and its disposal poses serious environmental and social problems. The aim of this study was to isolate degradative strains from kitchen waste and to develop a novel and effective microbial agent. One hundred and four strains were isolated from kitchen waste and the 84 dominant strains were used to inoculate protein-, starch-, fat- and cellulose-containing media for detecting their degradability. Twelve dominant strains of various species with high degradability (eight bacteria, one actinomycetes and three fungi) were selected to develop a compound microbial agent "YH" and five strains of these species including H7 (Brevibacterium epidermidis), A3 (Paenibacillus polymyxa), E3 (Aspergillus japonicus), F9 (Aspergillus versicolor) and A5 (Penicillium digitatum), were new for kitchen waste degradation...
February 21, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28278490/outcomes-after-oesophageal-perforation-a-retrospective-cohort-study-of-patients-with-different-aetiologies
#3
T T Law, J Yl Chan, D Kk Chan, D Tong, I Yh Wong, F Sy Chan, S Law
INTRODUCTION: The mortality rate after oesophageal perforation is high despite advances in operative and non-operative techniques. In this study, we sought to identify risk factors for hospital mortality. METHODS: We retrospectively examined patients treated for oesophageal perforation in a university teaching hospital in Hong Kong between January 1997 and December 2013. Their demographic and clinical characteristics, aetiology, management strategies, and outcomes were recorded and analysed...
March 10, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28263345/group-b-streptococci-in-sushi-and-sashimi
#4
Tse Hsien Koh, Delphine Yh Cao, Boon Ching Khoo, Lan Huay Ong, Fionicca Teo, Terry Wp Tan
No abstract text is available yet for this article.
February 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28242766/understanding-the-models-of-community-hospital-rehabilitation-activity-mocha-a-mixed-methods-study
#5
John Gladman, John Buckell, John Young, Andrew Smith, Clare Hulme, Satti Saggu, Mary Godfrey, Pam Enderby, Elizabeth Teale, Roberto Longo, Brenda Gannon, Claire Holditch, Heather Eardley, Helen Tucker
INTRODUCTION: To understand the variation in performance between community hospitals, our objectives are: to measure the relative performance (cost efficiency) of rehabilitation services in community hospitals; to identify the characteristics of community hospital rehabilitation that optimise performance; to investigate the current impact of community hospital inpatient rehabilitation for older people on secondary care and the potential impact if community hospital rehabilitation was optimised to best practice nationally; to examine the relationship between the configuration of intermediate care and secondary care bed use; and to develop toolkits for commissioners and community hospital providers to optimise performance...
February 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28240328/hypervalency-secondary-bonding-and-hydrogen-bonding-siblings-under-the-skin
#6
Robert H Crabtree
In hypervalent bonding (HVB), secondary bonding (SB) and hydrogen bonding (HB) a nucleophilic and an electrophilic partner form a new bond that is based on a similar bonding pattern across the whole series of interactions. The electrostatic contribution is reflected in the 'σ hole' model in which a positive patch on E attracts the nucleophilic component. The nucleophile, Y, possesses a corresponding negative patch, resulting in a linear structure YE-X having one strong E-X bond and one weaker, longer YE interaction; this is considered as a SB interaction between Y and E...
March 21, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28237753/tunable-and-purified-luminescence-via-energy-transfer-and-delamination-of-lrh-r-tb-y-composites-with-8-hydroxypyrene-1-3-6-trisulphonate
#7
Feifei Su, Chenyu Liu, Yan Yang, Shulan Ma, Genban Sun, Xiaojing Yang
This work demonstrates tunable and purified luminescence via one-step delamination of HPTS/OS-LRH composites (HPTS is trisodium 8-hydroxy-pyrene-1,3,6-trisulphonate, OS is sodium salt of 1-octane sulfonic acid, LRH is layered rare-earth hydroxide, R=Tb, Y) along with energy transfer. The HPTSxOS1-x-LTbyY1-yH composites presented varied luminescence behavior depending on their physical state. In solid state, dual-color luminescence was observed: blue-dominant emissions (437nm) for HPTSxOS1-x-LTbH, and blue- (437nm) to green-dominant (516nm) luminescence for HPTS0...
February 17, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28213369/drug-induced-liver-injury-with-oral-anticoagulants-a-threat-or-not
#8
EDITORIAL
Tatjana S Potpara, Gregory Yh Lip
No abstract text is available yet for this article.
February 17, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28203260/yin-cold-or-yang-heat-syndrome-type-of-traditional-chinese-medicine-was-associated-with-the-epidermal-growth-factor-receptor-gene-status-in-non-small-cell-lung-cancer-patients-confirmation-of-a-tcm-concept
#9
Yan-Juan Zhu, Hai-Bo Zhang, Li-Rong Liu, Yi-Hong Liu, Fu-Li Zhang, Jian-Ping Bai, Yong Li, Yan-Chun Qu, Xin Qu, Xian Chen, Yan Li, Shu-Yi Luo, Ai-Hua Ou
Traditional Chinese Medicine (TCM) therapies should be tailored according to the different syndrome types. In order to identify the relationship between the TCM Yin-cold (YC) or Yang-heat (YH) syndrome types and the EGFR gene status, we prospectively studied 310 NSCLC patients. TCM YH or YC was diagnosed by three TCM experts. TCM symptoms and signs were entered into a binary cluster analysis. The relationships between the EGFR gene status, YH or YC syndrome types, and classification by cluster analysis were analyzed using the chi-square test and multivariate logistic regression...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28183811/annexin-ii-binding-immunoglobulins-in-patients-with-lupus-nephritis-and-their-correlation-with-disease-manifestations
#10
Kwok Fan Cheung, Susan Yung, Mel Km Chau, Desmond Yh Yap, Kwok Wah Chan, Cheuk Kwong Lee, Colin So Tang, Tak Mao Chan
Annexin II on mesangial cell surface mediates the binding of anti-dsDNA antibodies and consequent downstream inflammatory and fibrotic processes. We investigated the clinical relevance of circulating annexin II-binding immunoglobulins in patients with severe proliferative lupus nephritis, and renal annexin II expression in relation to progression of nephritis in NZBWF1/J mice. Annexin II-binding immunoglobulins in serum were measured by ELISA. Ultrastructural localization of annexin II was determined by electron microscopy...
February 9, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28183405/prevalence-and-determinants-of-anxiety-and-depression-in-end-stage-renal-disease-esrd-a-comparison-between-esrd-patients-with-and-without-coexisting-diabetes-mellitus
#11
Russell Kl Yoong, Nandakumar Mooppil, Eric Yh Khoo, Stanton P Newman, Vanessa Yw Lee, Augustine Wc Kang, Konstadina Griva
OBJECTIVE: To compare anxiety and/or depressive symptoms between patients with end-stage renal disease with and without comorbid diabetes and identify factors associated with symptoms of distress in this population. METHODS: Data from two studies (conducted between 2010 and 2014) were pooled. A total of 526 patients on hemodialysis (68.8% with diabetes) completed the Hospital Anxiety and Depression Scale (HADS). Elevated symptoms were defined as HADS-Anxiety or HADS-Depression≥8...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28159490/chemohormonal-therapy-in-metastatic-hormone-sensitive-prostate-cancer-sweeney-cj-chen-yh-carducci-m-liu-g-jarrard-df-eisenberger-m-wong-yn-hahn-n-kohli-m-cooney-mm-dreicer-r-vogelzang-nj-picus-j-shevrin-d-hussain-m-garcia-ja-dipaola-rs-department-of-medicine
#12
Eggener Scott
BACKGROUND: Androgen deprivation therapy (ADT) has been the backbone of treatment for metastatic prostate cancer since the 1940s. We assessed whether concomitant treatment with ADT plus docetaxel would result in longer overall survival than that with ADT alone. METHODS: We assigned men with metastatic, hormone-sensitive prostate cancer to receive either ADT plus docetaxel (at a dose of 75mg per square meter of body-surface area every 3wk for 6 cycles) or ADT alone...
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28157170/theoretical-study-of-intramolecular-interactions-in-peri-substituted-naphthalenes-chalcogen-and-hydrogen-bonds
#13
Goar Sánchez-Sanz, Ibon Alkorta, José Elguero
A theoretical study of the peri interactions, both intramolecular hydrogen (HB) and chalcogen bonds (YB), in 1-hydroxy-8YH-naphthalene, 1,4-dihydroxy-5,8-di-YH-naphthalene, and 1,5-dihydroxy-4,8-di-YH-naphthalene, with Y = O, S, and Se was carried out. The systems with a OH:Y hydrogen bond are the most stable ones followed by those with a chalcogen O:Y interaction, those with a YH:O hydrogen bond (Y = S and Se) being the least stable ones. The electron density values at the hydrogen bond critical points indicate that they have partial covalent character...
February 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28145121/redox-driven-conformational-dynamics-in-a-photosystem-ii-inspired-%C3%AE-hairpin-maquette-determined-through-spectroscopy-and-simulation
#14
Hyea Hwang, Tyler G McCaslin, Anthony Hazel, Cynthia V Pagba, Christina M Nevin, Anna Pavlova, Bridgette A Barry, James C Gumbart
Tyrosine-based radical transfer plays an important role in photosynthesis, respiration, and DNA synthesis. Radical transfer can occur either by electron transfer (ET) or proton coupled electron transfer (PCET), depending on the pH. Reversible conformational changes in the surrounding protein matrix may control reactivity of radical intermediates. De novo designed Peptide A is a synthetic 18 amino-acid β-hairpin, which contains a single tyrosine (Y5) and carries out a kinetically significant PCET reaction between Y5 and a cross-strand histidine (H14)...
February 13, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28130180/optimal-vitamin-d-status-and-its-relationship-with-bone-and-mineral-metabolism-in-hong-kong-chinese
#15
Raymond Yh Leung, Bernard My Cheung, Uyen-Sa Nguyen, Annie Wc Kung, Kathryn Cb Tan, Ching-Lung Cheung
BACKGROUND: Although 25-hydroxyvitamin D (25[OH]D) is commonly used to define vitamin D status, there is no consensus on the cutoff levels for vitamin D deficiency and insufficiency. In this study, we aimed to identify the 25(OH)D threshold that maximally suppressed parathyroid hormone (PTH) in Hong Kong Chinese population. METHODS: The study included 5276 participants (70% female) of the Hong Kong Osteoporosis Study aged 20 or above who had total 25(OH)D measured...
January 24, 2017: Bone
https://www.readbyqxmd.com/read/28062884/extended-spectrum-beta-lactamase-producing-enterobacteriaceae-in-retail-chicken-meat-in-singapore
#16
LETTER
Eugene Jz Lim, Si Xian Ho, Delphine Yh Cao, Quek Choon Lau, Tse Hsien Koh, Li Yang Hsu
No abstract text is available yet for this article.
December 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28058849/cha2ds2-vasc-score-risk-factors-as-predictors-of-stroke-after-acute-coronary-syndrome-can-we-really-be-sure-there-is-no-atrial-fibrillation
#17
Michał Mazurek, Gregory Yh Lip
No abstract text is available yet for this article.
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28035052/screening-for-retinopathy-of-prematurity-and-treatment-outcome-in-a-tertiary-hospital-in-hong-kong
#18
L Pl Iu, C Hy Lai, M Cy Fan, I Yh Wong, J Sm Lai
INTRODUCTION: Studies on the prevalence and severity of retinopathy of prematurity in the local population are scarce. This study aimed to evaluate the prevalence, screening, and treatment outcome of retinopathy of prematurity in a tertiary hospital in Hong Kong. METHODS: This cross-sectional study with internal comparison was conducted at Queen Mary Hospital, Hong Kong. The study evaluated 89 premature infants who were born at the hospital and were screened for retinopathy of prematurity, in accordance with the 2008 British Guidelines, between January 2013 and December 2013...
December 30, 2016: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28029424/the-utility-of-a-country-specific-bartonella-henselae-antigen-in-an-igm-indirect-fluorescent-antibody-assay-for-the-improved-diagnosis-of-cat-scratch-disease
#19
Hidehiro Tsuneoka, Masashi Yanagihara, Ayano Tanimoto, Nobuko Tokuda, Ken-Ichiro Otsuyama, Junzo Nojima, Kiyoshi Ichihara
Bartonella henselae strains genetically differ among nations. The utility of Japanese-specific YH-01 strain was investigated in developing indirect fluorescence antibody assay (IFA) for IgM in comparison with conventional IFA employing Houston-1 strain by testing 100 Japanese patients suspected of cat scratch disease. The country-specific IFA greatly improved the accuracy of diagnosis.
October 11, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27990565/characterization-of-apple-stem-grooving-virus-and-apple-chlorotic-leaf-spot-virus-identified-in-a-crab-apple-tree
#20
Yongqiang Li, Congliang Deng, Yong Bian, Xiaoli Zhao, Qi Zhou
Apple stem grooving virus (ASGV), apple chlorotic leaf spot virus (ACLSV), and prunus necrotic ringspot virus (PNRSV) were identified in a crab apple tree by small RNA deep sequencing. The complete genome sequence of ACLSV isolate BJ (ACLSV-BJ) was 7554 nucleotides and shared 67.0%-83.0% nucleotide sequence identity with other ACLSV isolates. A phylogenetic tree based on the complete genome sequence of all available ACLSV isolates showed that ACLSV-BJ clustered with the isolates SY01 from hawthorn, MO5 from apple, and JB, KMS and YH from pear...
April 2017: Archives of Virology
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