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https://www.readbyqxmd.com/read/28203260/yin-cold-or-yang-heat-syndrome-type-of-traditional-chinese-medicine-was-associated-with-the-epidermal-growth-factor-receptor-gene-status-in-non-small-cell-lung-cancer-patients-confirmation-of-a-tcm-concept
#1
Yan-Juan Zhu, Hai-Bo Zhang, Li-Rong Liu, Yi-Hong Liu, Fu-Li Zhang, Jian-Ping Bai, Yong Li, Yan-Chun Qu, Xin Qu, Xian Chen, Yan Li, Shu-Yi Luo, Ai-Hua Ou
Traditional Chinese Medicine (TCM) therapies should be tailored according to the different syndrome types. In order to identify the relationship between the TCM Yin-cold (YC) or Yang-heat (YH) syndrome types and the EGFR gene status, we prospectively studied 310 NSCLC patients. TCM YH or YC was diagnosed by three TCM experts. TCM symptoms and signs were entered into a binary cluster analysis. The relationships between the EGFR gene status, YH or YC syndrome types, and classification by cluster analysis were analyzed using the chi-square test and multivariate logistic regression...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28183811/annexin-ii-binding-immunoglobulins-in-patients-with-lupus-nephritis-and-their-correlation-with-disease-manifestations
#2
Kwok Fan Cheung, Susan Yung, Mel Km Chau, Desmond Yh Yap, Kwok Wah Chan, Cheuk Kwong Lee, Colin So Tang, Tak Mao Chan
Annexin II on mesangial cell surface mediates the binding of anti-dsDNA antibodies and consequent downstream inflammatory and fibrotic processes. We investigated the clinical relevance of circulating annexin II-binding immunoglobulins in patients with severe proliferative lupus nephritis, and renal annexin II expression in relation to progression of nephritis in NZBWF1/J mice. Annexin II-binding immunoglobulins in serum were measured by ELISA. Ultrastructural localization of annexin II was determined by electron microscopy...
February 9, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28183405/prevalence-and-determinants-of-anxiety-and-depression-in-end-stage-renal-disease-esrd-a-comparison-between-esrd-patients-with-and-without-coexisting-diabetes-mellitus
#3
Russell Kl Yoong, Nandakumar Mooppil, Eric Yh Khoo, Stanton P Newman, Vanessa Yw Lee, Augustine Wc Kang, Konstadina Griva
OBJECTIVE: To compare anxiety and/or depressive symptoms between patients with end-stage renal disease with and without comorbid diabetes and identify factors associated with symptoms of distress in this population. METHODS: Data from two studies (conducted between 2010 and 2014) were pooled. A total of 526 patients on hemodialysis (68.8% with diabetes) completed the Hospital Anxiety and Depression Scale (HADS). Elevated symptoms were defined as HADS-Anxiety or HADS-Depression≥8...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28159490/chemohormonal-therapy-in-metastatic-hormone-sensitive-prostate-cancer-sweeney-cj-chen-yh-carducci-m-liu-g-jarrard-df-eisenberger-m-wong-yn-hahn-n-kohli-m-cooney-mm-dreicer-r-vogelzang-nj-picus-j-shevrin-d-hussain-m-garcia-ja-dipaola-rs-department-of-medicine
#4
Eggener Scott
BACKGROUND: Androgen deprivation therapy (ADT) has been the backbone of treatment for metastatic prostate cancer since the 1940s. We assessed whether concomitant treatment with ADT plus docetaxel would result in longer overall survival than that with ADT alone. METHODS: We assigned men with metastatic, hormone-sensitive prostate cancer to receive either ADT plus docetaxel (at a dose of 75mg per square meter of body-surface area every 3wk for 6 cycles) or ADT alone...
February 1, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28157170/theoretical-study-of-intramolecular-interactions-in-peri-substituted-naphthalenes-chalcogen-and-hydrogen-bonds
#5
Goar Sánchez-Sanz, Ibon Alkorta, José Elguero
A theoretical study of the peri interactions, both intramolecular hydrogen (HB) and chalcogen bonds (YB), in 1-hydroxy-8YH-naphthalene, 1,4-dihydroxy-5,8-di-YH-naphthalene, and 1,5-dihydroxy-4,8-di-YH-naphthalene, with Y = O, S, and Se was carried out. The systems with a OH:Y hydrogen bond are the most stable ones followed by those with a chalcogen O:Y interaction, those with a YH:O hydrogen bond (Y = S and Se) being the least stable ones. The electron density values at the hydrogen bond critical points indicate that they have partial covalent character...
February 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28145121/redox-driven-conformational-dynamics-in-a-photosystem-ii-inspired-%C3%AE-hairpin-maquette-determined-through-spectroscopy-and-simulation
#6
Hyea Hwang, Tyler G McCaslin, Anthony Hazel, Cynthia V Pagba, Christina M Nevin, Anna Pavlova, Bridgette A Barry, James C Gumbart
Tyrosine-based radical transfer plays an important role in photosynthesis, respiration, and DNA synthesis. Radical transfer can occur either by electron transfer (ET) or proton coupled electron transfer (PCET), depending on the pH. Reversible conformational changes in the surrounding protein matrix may control reactivity of radical intermediates. De novo designed Peptide A is a synthetic 18 amino-acid β-hairpin, which contains a single tyrosine (Y5) and carries out a kinetically significant PCET reaction between Y5 and a cross-strand histidine (H14)...
February 13, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28130180/optimal-vitamin-d-status-and-its-relationship-with-bone-and-mineral-metabolism-in-hong-kong-chinese
#7
Raymond Yh Leung, Bernard My Cheung, Uyen-Sa Nguyen, Annie Wc Kung, Kathryn Cb Tan, Ching-Lung Cheung
BACKGROUND: Although 25-hydroxyvitamin D (25[OH]D) is commonly used to define vitamin D status, there is no consensus on the cutoff levels for vitamin D deficiency and insufficiency. In this study, we aimed to identify the 25(OH)D threshold that maximally suppressed parathyroid hormone (PTH) in Hong Kong Chinese population. METHODS: The study included 5276 participants (70% female) of the Hong Kong Osteoporosis Study aged 20 or above who had total 25(OH)D measured...
January 24, 2017: Bone
https://www.readbyqxmd.com/read/28062884/extended-spectrum-beta-lactamase-producing-enterobacteriaceae-in-retail-chicken-meat-in-singapore
#8
Eugene Jz Lim, Si Xian Ho, Delphine Yh Cao, Quek Choon Lau, Tse Hsien Koh, Li Yang Hsu
No abstract text is available yet for this article.
December 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28058849/cha2ds2-vasc-score-risk-factors-as-predictors-of-stroke-after-acute-coronary-syndrome-can-we-really-be-sure-there-is-no-atrial-fibrillation
#9
Michał Mazurek, Gregory Yh Lip
No abstract text is available yet for this article.
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28035052/screening-for-retinopathy-of-prematurity-and-treatment-outcome-in-a-tertiary-hospital-in-hong-kong
#10
L Pl Iu, C Hy Lai, M Cy Fan, I Yh Wong, J Sm Lai
INTRODUCTION: Studies on the prevalence and severity of retinopathy of prematurity in the local population are scarce. This study aimed to evaluate the prevalence, screening, and treatment outcome of retinopathy of prematurity in a tertiary hospital in Hong Kong. METHODS: This cross-sectional study with internal comparison was conducted at Queen Mary Hospital, Hong Kong. The study evaluated 89 premature infants who were born at the hospital and were screened for retinopathy of prematurity, in accordance with the 2008 British Guidelines, between January 2013 and December 2013...
December 30, 2016: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28029424/the-utility-of-a-country-specific-bartonella-henselae-antigen-in-an-igm-indirect-fluorescent-antibody-assay-for-the-improved-diagnosis-of-cat-scratch-disease
#11
Hidehiro Tsuneoka, Masashi Yanagihara, Ayano Tanimoto, Nobuko Tokuda, Ken-Ichiro Otsuyama, Junzo Nojima, Kiyoshi Ichihara
Bartonella henselae strains genetically differ among nations. The utility of Japanese-specific YH-01 strain was investigated in developing indirect fluorescence antibody assay (IFA) for IgM in comparison with conventional IFA employing Houston-1 strain by testing 100 Japanese patients suspected of cat scratch disease. The country-specific IFA greatly improved the accuracy of diagnosis.
October 11, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27990565/characterization-of-apple-stem-grooving-virus-and-apple-chlorotic-leaf-spot-virus-identified-in-a-crab-apple-tree
#12
Yongqiang Li, Congliang Deng, Yong Bian, Xiaoli Zhao, Qi Zhou
Apple stem grooving virus (ASGV), apple chlorotic leaf spot virus (ACLSV), and prunus necrotic ringspot virus (PNRSV) were identified in a crab apple tree by small RNA deep sequencing. The complete genome sequence of ACLSV isolate BJ (ACLSV-BJ) was 7554 nucleotides and shared 67.0%-83.0% nucleotide sequence identity with other ACLSV isolates. A phylogenetic tree based on the complete genome sequence of all available ACLSV isolates showed that ACLSV-BJ clustered with the isolates SY01 from hawthorn, MO5 from apple, and JB, KMS and YH from pear...
December 18, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27968874/time-since-migration-and-breastfeeding-duration-among-mainland-chinese-immigrant-women-a-two-phase-prospective-cohort-study
#13
Kris Y W Lok, Dorothy L Bai, Noel Pt Chan, Janet Yh Wong, Marie Tarrant
BACKGROUND: Substantial breastfeeding disparities exist among various ethnic and racial groups, and between mainland Chinese immigrants and native born Chinese women. However, few studies have addressed the effect of migration on mainland Chinese immigrants or the effect of time since migration on breastfeeding practices. Hong Kong, SAR, China, provides a unique opportunity since immigrants are from one country and share the same race and ethnic origin. Thus, the aim of this study was to examine the effect of time since migration on the breastfeeding practices of native Hong Kong-born and mainland Chinese immigrant mothers in Hong Kong...
October 2016: Lancet
https://www.readbyqxmd.com/read/27920402/posterior-facet-talocalcaneal-non-osseous-coalition-an-uncommon-but-easily-missed-cause-of-hindfoot-pain
#14
A Yh Tsang, Y Y Cheuk, A Ws Au-Yeung
No abstract text is available yet for this article.
December 2016: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/27920261/effects-of-repetitive-transcranial-magnetic-stimulation-combined-with-sensory-cueing-on-unilateral-neglect-in-subacute-patients-with-right-hemispheric-stroke-a-randomized-controlled-study
#15
Nicole Yh Yang, Kenneth Nk Fong, Cecilia Wp Li-Tsang, D Zhou
OBJECTIVE: To compare the effects of rTMS combined with sensory cueing, rTMS alone, and conventional rehabilitation on unilateral neglect, hemiplegic arm functions and performance of activities of daily living. DESIGN: A single-blinded randomized controlled trial. SETTING: A convalescent hospital. SUBJECTS: Sixty inpatients with left unilateral neglect after stroke. INTERVENTIONS: Patients were randomly assigned to three groups: rTMS combined with sensory cueing, rTMS, and conventional rehabilitation alone...
December 5, 2016: Clinical Rehabilitation
https://www.readbyqxmd.com/read/27913171/effects-of-hydraulic-retention-time-hrt-on-denitrification-using-waste-activated-sludge-thermal-hydrolysis-liquid-and-acidogenic-liquid-as-carbon-sources
#16
Yiding Guo, Liang Guo, Mei Sun, Yangguo Zhao, Mengchun Gao, Zonglian She
Waste activated sludge (WAS) internal carbon source can efficiently and economically enhance denitrification, and hydraulic retention time (HRT) is one of the most important operational parameters for denitrification. The effects of HRT on denitrification were investigated with WAS thermal hydrolysis liquid and acidogenic liquid as carbon sources in this study. The optimal HRT was 12h for thermal hydrolysis liquid and 8h for acidogenic liquid, with NO3(-)-N removal efficiency of 91.0% and 97.6%, respectively...
January 2017: Bioresource Technology
https://www.readbyqxmd.com/read/27912736/citrus-junos-tanaka-peel-ameliorates-hepatic-lipid-accumulation-in-hepg2-cells-and-in-mice-fed-a-high-cholesterol-diet
#17
Eun Ju Shin, Jae Ho Park, Mi Jeong Sung, Min-Yu Chung, Jin-Taek Hwang
BACKGROUND: Citrus junos Tanaka (yuja), a yellow-coloured citrus fruit has traditionally been consumed in Korea, Japan, and China and has been found effective in preventing certain diseases. However, the inhibitory effect of yuja on hepatic lipid accumulation has not been clearly elucidated thus far. METHODS: The inhibitory effect of yuja on hepatic lipid accumulation was investigated in both cell culture and mouse models. We investigated the inhibitory effect of ethanol extract of yuja peel (YE) using HepG2 cells...
December 3, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27909151/cerebrovascular-disease-associated-risk-factors-and-antithrombotic-therapy-in-a-population-screening-cohort-insights-from-the-belgian-heart-rhythm-week-programme
#18
Marco Proietti, Georges H Mairesse, Peter Goethals, Christophe Scavee, Johan Vijgen, Ivan Blankoff, Yves Vandekerckhove, Gregory Yh Lip
BACKGROUND: Cerebrovascular disease confers a major healthcare burden worldwide and is a major cause of death and disability. Several well-established risk factors, such as atrial fibrillation (AF), are associated with cerebrovascular disease and antithrombotic therapy reduces risk. DESIGN: This study was a subgroup analysis from the Belgian Heart Rhythm Week, a nationwide AF awareness programme. METHODS: We studied subjects screened between 2012 and 2014 with available data on clinical risk factors and antithrombotic treatment...
December 1, 2016: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/27855103/hyaluronic-acid-binding-sperm-selection-for-assisted-reproduction-treatment-habselect-study-protocol-for-a-multicentre-randomised-controlled-trial
#19
K D Witt, L Beresford, S Bhattacharya, K Brian, A Coomarasamy, R Hooper, J Kirkman-Brown, Y Khalaf, S E Lewis, A Pacey, S Pavitt, R West, D Miller
INTRODUCTION: The selection of a sperm with good genomic integrity is an important consideration for improving intracytoplasmic sperm injection (ICSI) outcome. Current convention selects sperm by vigour and morphology, but preliminary evidence suggests selection based on hyaluronic acid binding may be beneficial. The aim of the Hyaluronic Acid Binding Sperm Selection (HABSelect) trial is to determine the efficacy of hyaluronic acid (HA)-selection of sperm versus conventionally selected sperm prior to ICSI on live birth rate (LBR)...
October 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27815537/pre-participation-cardiovascular-evaluation-for-athletic-participants-to-prevent-sudden-death-position-paper-from-the-ehra-and-the-eacpr-branches-of-the-esc-endorsed-by-aphrs-hrs-and-solaece
#20
Lluís Mont, Antonio Pelliccia, Sanjay Sharma, Alessandro Biffi, Mats Borjesson, Josep Brugada Terradellas, Francois Carré, Eduard Guasch, Hein Heidbuchel, André La Gerche, Rachel Lampert, William McKenna, Michail Papadakis, Silvia G Priori, Mauricio Scanavacca, Paul Thompson, Christian Sticherling, Sami Viskin, Mathew Wilson, Domenico Corrado, Gregory Yh Lip, Bulent Gorenek, Carina Blomström Lundqvist, Bela Merkely, Gerhard Hindricks, Antonio Hernández-Madrid, Deirdre Lane, Guiseppe Boriani, Calambur Narasimhan, Manlio F Marquez, David Haines, Judith Mackall, Pedro Manuel Marques-Vidal, Ugo Corra, Martin Halle, Monica Tiberi, Josef Niebauer, Massimo Piepoli
No abstract text is available yet for this article.
January 2017: European Journal of Preventive Cardiology
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