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Neuro-endocrine

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https://www.readbyqxmd.com/read/29896129/gut-brain-axis-and-mood-disorder
#1
REVIEW
Lu Liu, Gang Zhu
Humans have over 100 trillion bacteria, highly abundant in the intestinal tract. Evidence suggests that intestinal microbiota is associated with the neuro-endocrine-immune pathways and can be associated with various mood disorders. This review summarizes findings from studies looking into neurobiochemical, neuroendocrine, and neuroimmune system mechanisms of the gut-brain axis to determine the relationship between intestinal microbiota and mood disorders. The effect of prebiotics, probiotics and antibiotics on mood disorders are also discussed, with the aim to propose some new therapeutic strategies for mood disorders...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29869750/laryngeal-basaloid-squamous-cell-carcinoma-with-a-substantial-spindle-cell-component-case-presentation-and-updated-review-of-literature
#2
Deepak Pandiar, Sangeetha K Nayanar, Basavaraj Ankalkoti, Sajith Babu
Basaloid squamous cell carcinoma with spindle cell component is an uncommon aggressive variety of squamous cell carcinoma with only a few reported cases in literature. Histologically a combination of basaloid squamous cell carcinoma and spindle cell squamous cell carcinoma is appreciated and immunohistochemistry serves a role in differentiation from malignant neoplasms of salivary gland or neuro-endocrine origin. Prime treatment modality is combination of surgery and external beam radiotherapy. A case of basaloid squamous cell carcinoma with proliferation of bizarre mesenchymal component is being reported here with an updated literature review...
June 5, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29771216/mindfulness-based-cognitive-hypnotherapy-and-skin-disorders
#3
Philip D Shenefelt
Mindfulness-based cognitive hypnotherapy integrates mindfulness, cognitive-behavioral therapy, and hypnotherapy to improve physical, emotional, mental, and/or spiritual aspects of skin disorders. Meditation, including mindfulness meditation, and hypnosis both utilize trance phenomena to help produce focalization and specific improvements in skin disorders through psycho-neuro-endocrine-immunologic mechanisms. Hypnosis, cognitive hypnotherapy, focused meditation, and mindfulness meditation are discussed with respect to improving various skin disorders including acne, acne excoriée, alopecia areata, atopic dermatitis, congenital ichthyosiform erythroderma, dyshidrotic dermatitis, erythema nodosum, erythromelalgia, furuncles, glossodynia, herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus, neurodermatitis, nummular dermatitis, postherpetic neuralgia, prurigo nodularis, pruritus, psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo...
July 2018: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/29667849/defensive-coping-facilitated-a-smaller-cortisol-to-estradiol-ratio-and-a-higher-hypertension-risk-the-sabpa-study
#4
Leoné Malan, Andrea de Kock, Mark Hamer, Marike Cockeran, Nicolaas Theodor Malan
OBJECTIVES: Taxing psychosocial stress and defensive coping have been associated with hypoactivity in cortisol, a vasoconstrictive agent. Estradiol has vasodilatory properties with cardio- and neuroprotective effects. It can however also induce α1 -adrenergic vasoconstrictive responsiveness. We aimed to determine whether the cortisol-to-estradiol ratio (Cort:E2) may augment α1 -adrenergic responsiveness and hypertension risk when habitually using defensive coping. METHODS: African (n = 168) and Caucasian (n = 207) men and women (46 ± 9 years) were included...
April 18, 2018: Blood Pressure
https://www.readbyqxmd.com/read/29614774/the-brain-intestinal-mucosa-appendix-microbiome-brain-loop
#5
Luis Vitetta, Gemma Vitetta, Sean Hall
The brain and the gut are connected from early fetal life. The mother's exposure to microbial molecules is thought to exert in utero developmental effects on the fetus. These effects could importantly underpin the groundwork for subsequent pathophysiological mechanisms for achieving immunological tolerance and metabolic equilibrium post birth, events that continue through to 3-4 years of age. Furthermore, it is understood that the microbiome promotes cues that instruct the neonate's mucosal tissues and skin in the language of molecular and cellular biology...
April 1, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29546369/how-uv-light-touches-the-brain-and-endocrine-system-through-skin-and-why
#6
Andrzej T Slominski, Michal A Zmijewski, Przemyslaw M Plonka, Jerzy P Szaflarski, Ralf Paus
The skin, a self-regulating protective barrier organ, is empowered with sensory and computing capabilities to counteract the environmental stressors to maintain and restore disrupted cutaneous homeostasis. These complex functions are coordinated by a cutaneous neuro-endocrine system that also communicates in a bidirectional fashion with the central nervous, endocrine, and immune systems, all acting in concert to control body homeostasis. Although UV energy has played an important role in the origin and evolution of life, UV absorption by the skin not only triggers mechanisms that defend skin integrity and regulate global homeostasis but also induces skin pathology (e...
May 1, 2018: Endocrinology
https://www.readbyqxmd.com/read/29512793/gastrointestinal-neuro-endocrine-tumors-retrospective-study-of-36-cases
#7
Alia Zehani, Sarra Aloui, Ines Chelly, Slim Haouet, Nidhameddine Kchir
BACKGROUND: Neuroendocrine tumors (NETs) of the gastrointestinal tract are a heterogeneous group of tumors which have different malignant potential and evolution. The World Health Organization (WHO) has set up a new classification of gastrointestinal NETs in 2010. However, it does not evaluate the risk of malignancy for each tumor. AIM: To evaluate the prognostic impact of the WHO classification in 2010 by reclassifying the tumor according to new recommendations and to identify histoprognostic factors to better predict changes...
June 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29477026/a-case-series-of-closed-head-trauma-with-pituitary-stalk-disruption-resulting-in-hypopituitarism
#8
Khuram Khan, Saqib Saeed, Alexius Ramcharan, Sanjiv Gray
INTRODUCTION: Traumatic brain injury (TBI) is one of the main causes of morbidity and mortality in young trauma patients with resultant multi-organ effects. Hypopituitarism following TBI can be debilitating and life threatening. TBI which causes hypopituitarism may be characterized by a single head injury, such as from a motor vehicle accident, or by chronic repetitive head trauma, as seen in combative supports including boxing, kick-boxing, and football. In the majority of cases, a diagnosis of hypopituitarism can be entirely missed resulting in severe neuro-endocrine dysfunction...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29471911/the-neuro-endocrine-immune-relationship-in-pulmonary-and-pleural-tuberculosis-a-better-local-profile-in-pleural-fluid
#9
L D'Attilio, A Díaz, R D V Fernández, B Bongiovanni, N Santucci, G Dídoli, S Lioi, W Gardeñez, J L Naninni, A Del Rey, H Besedovsky, O Bottasso, M L Bay
BACKGROUND: Tuberculosis (TB) is a major health problem worldwide. In TB, the immune and central nervous systems modulate each other. The two main components of this network are the hypothalamic-pituitary-adrenal axis (HPA) and autonomic nervous system (ANS). OBJECTIVE: To elucidate neuro-endocrine-immune (NEI) interactions in pulmonary (PTB) or pleural (PLTB) TB, we analysed the relationship among compounds from these systems. METHODS: We quantified levels of catecholamines, hormones and cytokines in plasma from patients with PTB (n = 46) or PLTB (n = 12) and controls (n = 32), and in the pleural fluid from PLTB patients...
March 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29440947/psychological-stress-and-breast-cancer-incidence-a-systematic-review
#10
REVIEW
Valentina-Fineta Chiriac, Adriana Baban, Dan L Dumitrascu
Objective: Breast cancer is the world's leading cause of cancer mortality in women. Stress is an imminent risk factor with a documented negative impact on neuro-endocrine and immune system. Numerous epidemiological studies have investigated the link between stress and cancer, reporting contradictory results from no association to a close causal link. The impact of the topic and the lack of conclusion compelled this systematic review. Methods: A systematic review was carried out, including all literature studies from 1966 to 2016, investigating the relationship between stress and the occurrence of breast cancer...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29425971/competition-stage-influences-perceived-performance-but-does-not-affect-rating-of-perceived-exertion-and-salivary-neuro-endocrine-immune-markers-in-elite-young-basketball-players
#11
Ademir Felipe Schultz de Arruda, Marcelo Saldanha Aoki, Ana Carolina Paludo, Gustavo Drago, Alexandre Moreira
This study examined the effects of competition stage on the salivary concentration of testosterone (T), cortisol (C), alpha-amylase (sAA), and IL-1ß cytokine, perceived performance (PP) and session rating of perceived exertion (session-RPE) in elite youth basketball players (age, 15.8 ± 0.8 yrs.; stature, 190.9 ± 7.9 cm; body mass, 90.0 ± 16.9 kg) from two age-categories (U16; n = 7; U17; n = 7). Two winning playoff matches (FM; playing for the championship; 1 for each age-category) and two winning regular stage matches (RM; 1 for each age category, played against opponents ranked 2nd place), were assessed in the current study...
May 1, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29383891/-effects-of-the-acupoint-catgut-embedding-on-nerve-endocrine-immune-network-in-dysmenorrhea-rats
#12
Pan-Bi Chen, Jing Chen, Jin Cui, Xiao-Fang Yang
OBJECTIVE: To explore the underlying mechanism of acupoint catgut embedding in improving primary dysme-norrhea (PD) in rats based on functional activities of the neuro-endocrine-immune (NEI) network. METHODS: Forty female rats were equally randomized into blank control, PD model, medication, and acupoint catgut embedding groups. The PD model was established by subcutaneous injection of estradiol benzoate (0.5 mg/rat on the 1st and 10th d, and 0.2 mg/rat from 2nd to 9th d) and oxytocin (2 U/rat, i.p...
January 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29377285/retrospective-study-on-the-correlation-between-18-fluorodeoxyglucose-uptake-in-positron-emission-tomography-computer-tomography-and-tumour-volume-cytological-activity-as-assessed-with-ki-67-and-glut-1-staining-in-10-cases-of-merkel-cell-carcinoma
#13
LETTER
S Kitamura, T Yanagi, Y Inamura-Takashima, K Imafuku, H Hata, J Uehara, Y Ishida, A Otsuka, K Hirata, H Shimizu
No abstract text is available yet for this article.
January 29, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29333681/myotropic-activity-and-immunolocalization-of-selected-neuropeptides-of-the-burying-beetle-nicrophorus-vespilloides-coleoptera-silphidae
#14
Arkadiusz Urbański, Jan Lubawy, Paweł Marciniak, Grzegorz Rosiński
Burying beetles (Nicrophorus sp.) are necrophagous insects with developed parental care. Genome of Nicrophorus vespilloides has been recently sequenced, which makes them interesting model organism in behavioral ecology. However, we know very little about their physiology, including the functioning of their neuroendocrine system. In this study, one of the physiological activities of proctolin, myosuppressin (Nicve-MS), myoinhibitory peptide (Trica-MIP-5) and the short neuropeptide F (Nicve-sNPF) in N. vespilloides have been investigated...
January 15, 2018: Insect Science
https://www.readbyqxmd.com/read/29322004/thoughts-modulate-the-expression-of-inflammatory-genes-and-may-improve-the-coronary-blood-flow-in-patients-after-a-myocardial-infarction
#15
Carlo Dal Lin, Mariela Marinova, Giorgio Rubino, Elisabetta Gola, Alessandra Brocca, Giorgia Pantano, Laura Brugnolo, Cristiano Sarais, Umberto Cucchini, Biancarosa Volpe, Chiara Cavalli, Maura Bellio, Emilia Fiorello, Sofia Scali, Mario Plebani, Sabino Iliceto, Francesco Tona
Background: Mental stress is one of the main risk factors for cardiovascular disease. Meditation and music listening are two techniques that are able to counteract it through the activation of specific brain areas, eliciting the so-called Relaxing Response (RR). Epidemiological evidence reveals that the RR practice has a beneficial prognostic impact on patients after myocardial infarction. We aimed to study the possible molecular mechanisms of RR underlying these findings. Methods: We enrolled 30 consecutive patients after myocardial infarction and 10 healthy controls...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29299757/benign-tumors-of-the-pancreas-radical-surgery-versus-parenchyma-sparing-local-resection-the-challenge-facing-surgeons
#16
EDITORIAL
Hans G Beger
Pancreaticoduodenectomy and left-sided pancreatectomy are the surgical treatment standards for tumors of the pancreas. Surgeons, who are requested to treat patients with benign tumors, using standard oncological resections, face the challenge of sacrificing pancreatic and extra-pancreatic tissue. Tumor enucleation, pancreatic middle segment resection and local, duodenum-preserving pancreatic head resections are surgical procedures increasingly used as alternative treatment modalities compared to classical pancreatic resections...
March 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29163364/telomere-length-in-preterm-infants-a-promising-biomarker-of-early-adversity-and-care-in-the-neonatal-intensive-care-unit
#17
Livio Provenzi, Giunia Scotto di Minico, Roberto Giorda, Rosario Montirosso
Preterm infants present an immature neurobehavioral profile at birth, even in absence of severe brain injuries and perinatal complications. As such, they require a long-lasting hospitalization in the Neonatal Intensive Care Unit (NICU), which is thought to grant at-risk newborns' survival, but still entails a number of physical, painful, and socio-emotional stressors. Hence, preterm birth and NICU stay represent an early adverse experience, which has been linked to detrimental consequences for neurological, neuro-endocrinal, behavioral, and socio-emotional development, as well as to disease later in life...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29142191/immune-neuroendocrine-interactions-evolution-ecology-and-susceptibility-to-illness
#18
Johanna M C Blom, Enzo Ottaviani
The integration between immune and neuroendocrine systems is crucial for maintaining homeostasis from invertebrates to humans. In the first, the phagocytic cell, i.e., the immunocyte, is the main actor, while in the latter, the principle player is the lymphocyte. Immunocytes are characterized by the presence of pro-opiomelanocortin (POMC) peptides, CRH, and other molecules that display a significant similarity to their mammalian counterparts regarding their functions, as both are mainly involved in fundamental functions such as immune (chemotaxis, phagocytosis, cytotoxicity, etc...
November 16, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29124696/psycho-neuro-endocrine-immunology-a-psychobiological-concept
#19
REVIEW
Katlein França, Torello M Lotti
Psycho-Neuro-Endocrine-Immunology (P.N.E.I.) is a scientific field of study that investigates the link between bidirectional communications among the nervous system, the endocrine system, and the immune system and the correlations of this cross-talk with physical health. The P.N.E.I. innovative medical approach represents a paradigm shift from a strictly biomedical view of health and disease taken as hermetically sealed compartments to a more interdisciplinary one. The key element of P.N.E.I. approach is represented by the concept of bidirectional cross-talk between the psychoneuroendocrine and immune systems...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098879/regulation-of-circulating-chromogranin-b-levels-in-heart-failure
#20
Felix M Heidrich, Carolin Melz, Mimi S Buechau, Christian Pfluecke, Silvio Quick, Uwe Speiser, David M Poitz, Antje Augstein, Tobias Ruf, Nadine K Wässnig, Akram Youssef, Ruth H Strasser, Stephan Wiedemann
BACKGROUND: Chromogranin B (CGB) regulates B-type natriuretic peptide (BNP) production. Circulating CGB levels are elevated in heart failure (HF) animal models and HF patients, but also increase in healthy individuals in response to physical activity. Therefore, CGB seems to integrate information from myocardial stress and systemic neuro-endocrine activation. Substantial gaps remain in our understanding of CGB regulation in HF. METHODS AND RESULTS: We conducted a retrospective registry study including 372 patients...
February 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
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