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https://www.readbyqxmd.com/read/29148562/recurrence-of-reported-cdh23-mutations-causing-dfnb12-in-a-special-cohort-of-south-indian-hearing-impaired-assortative-mating-families-an-evaluation
#1
Paridhy Vanniya S, Jayasankaran Chandru, Amritkumar Pavithra, Justin Margret Jeffrey, Murugesan Kalaimathi, Rajagopalan Ramakrishnan, Natarajan P Karthikeyen, Srisailapathy C R Srikumari
Mutations in CDH23 are known to cause autosomal-recessive nonsyndromic hearing loss (DFNB12). Until now, there was only one study describing its frequency in Indian population. We screened for CDH23 mutations to identify prevalent and recurring mutations among South Indian assortative mating hearing-impaired individuals who were identified as non-DFNB1 (GJB2 and GJB6). Whole-exome sequencing was performed in individuals found to be heterozygous for CDH23 to determine whether there was a second pathogenic allele...
November 17, 2017: Annals of Human Genetics
https://www.readbyqxmd.com/read/29146993/height-associated-variants-demonstrate-assortative-mating-in-human-populations
#2
Xiaoyin Li, Susan Redline, Xiang Zhang, Scott Williams, Xiaofeng Zhu
Understanding human mating patterns, which can affect population genetic structure, is important for correctly modeling populations and performing genetic association studies. Prior studies of assortative mating in humans focused on trait similarity among spouses and relatives via phenotypic correlations. Limited research has quantified the genetic consequences of assortative mating. The degree to which the non-random mating influences genetic architecture remains unclear. Here, we studied genetic variants associated with human height to assess the degree of height-related assortative mating in European-American and African-American populations...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29131310/tests-of-fit-of-historically-informed-models-of-african-american-admixture
#3
Jessica M Gross
OBJECTIVES: African American populations in the U.S. formed primarily by mating between Africans and Europeans over the last 500 years. To date, studies of admixture have focused on either a one-time admixture event or continuous input into the African American population from Europeans only. Our goal is to gain a better understanding of the admixture process by examining models that take into account (a) assortative mating by ancestry in the African American population, (b) continuous input from both Europeans and Africans, and (c) historically informed variation in the rate of African migration over time...
November 13, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29109277/gut-microbiomes-and-reproductive-isolation-in-drosophila
#4
Philip T Leftwich, Naomi V E Clarke, Matthew I Hutchings, Tracey Chapman
Experimental studies of the evolution of reproductive isolation (RI) in real time are a powerful way in which to reveal fundamental, early processes that initiate divergence. In a classic speciation experiment, populations of Drosophila pseudoobscura were subjected to divergent dietary selection and evolved significant positive assortative mating by diet. More recently, a direct role for the gut microbiome in determining this type of RI in Drosophila melanogaster has been proposed. Manipulation of the diet, and hence the gut microbiome, was reported to result in immediate assortative mating by diet, which could be eliminated by reducing gut microbes using antibiotics and recreated by adding back Lactobacillus plantarum We suggest that the evolutionary significance of this result is unclear...
November 6, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29063140/biocide-selective-tolc-independent-efflux-pumps-in-enterobacteriaceae
#5
Carmine J Slipski, George G Zhanel, Denice C Bay
Bacterial resistance to biocides used as antiseptics, dyes, and disinfectants is a growing concern in food preparation, agricultural, consumer manufacturing, and health care industries, particularly among Gram-negative Enterobacteriaceae, some of the most common community and healthcare-acquired bacterial pathogens. Biocide resistance is frequently associated with antimicrobial cross-resistance leading to reduced activity and efficacy of both antimicrobials and antiseptics. Multidrug resistant efflux pumps represent an important biocide resistance mechanism in Enterobacteriaceae...
October 23, 2017: Journal of Membrane Biology
https://www.readbyqxmd.com/read/29056455/genetic-coupling-of-female-mate-choice-with-polygenic-ecological-divergence-facilitates-stickleback-speciation
#6
Rachael A Bay, Matthew E Arnegard, Gina L Conte, Jacob Best, Nicole L Bedford, Shaugnessy R McCann, Matthew E Dubin, Yingguang Frank Chan, Felicity C Jones, David M Kingsley, Dolph Schluter, Catherine L Peichel
Ecological speciation with gene flow is widespread in nature [1], but it presents a conundrum: how are associations between traits under divergent natural selection and traits that contribute to assortative mating maintained? Theoretical models suggest that genetic mechanisms inhibiting free recombination between loci underlying these two types of traits (hereafter, "genetic coupling") can facilitate speciation [2-4]. Here, we perform a direct test for genetic coupling by mapping both divergent traits and female mate choice in a classic model of ecological speciation: sympatric benthic and limnetic threespine stickleback (Gasterosteus aculeatus)...
November 6, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29053357/the-roles-of-sexual-and-viability-selection-in-the-evolution-of-incomplete-reproductive-isolation-from-allopatry-to-sympatry
#7
Olivier Cotto, Maria R Servedio
In recent years, theoretical models have introduced the concept that ongoing hybridization between "good" species can occur because incomplete reproductive isolation can be a selected optimum. They furthermore show that positive frequency-dependent sexual selection, which is naturally generated by some of the underlying processes that lead to assortative mating, plays a key role in the evolution of incomplete reproductive isolation. This occurs, however, through different mechanisms in sympatric versus allopatric scenarios...
November 2017: American Naturalist
https://www.readbyqxmd.com/read/29040605/negative-assortative-mating-in-the-white-throated-sparrow
#8
Philip W Hedrick, Elaina M Tuttle, Rusty A Gonser
Non-random mating based on phenotype has been observed in a number of organisms, but a very high proportion of these examples are of assortative mating. The strongest example of negative-assortative mating is for white-striped versus tan-striped crown in the white-throated sparrow, where about 98% of the observed pairings (mated pairs or social pairs) are between mates with different phenotypes and the correlation between mating types is -0.964. Although non-random mating has been explored theoretically for decades, these models have generally not focused on specific well-documented examples...
October 10, 2017: Journal of Heredity
https://www.readbyqxmd.com/read/29035717/concordance-of-health-states-in-couples-analysis-of-self-reported-nurse-administered-and-blood-based-biomarker-data-in-the-uk-understanding-society-panel
#9
Apostolos Davillas, Stephen Pudney
We use self-reported health measures, nurse-administered measurements and blood-based biomarkers to examine the concordance between health states of partners in marital/cohabiting relationships in the UK. A model of cumulative health exposures is used to interpret the empirical pattern of between-partner health correlation in relation to elapsed relationship duration, allowing us to distinguish non-causal correlation due to assortative mating from potentially causal effects of shared lifestyle and environmental factors...
September 29, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/29035692/the-development-of-chronic-physical-aggression-a-bio-psycho-social-model-for-the-next-generation-of-preventive-interventions
#10
Richard E Tremblay, Frank Vitaro, Sylvana M Côté
This review describes a bio-psycho-social approach to understanding and preventing the development of chronic physical aggression. The debate on the developmental origins of aggression has historically opposed genetic and environmental mechanisms. Recent studies have shown that the frequency of physical aggression peaks in early childhood and then decreases until old age. Molecular genetic studies and twin studies have confirmed important genetic influences. However, recent epigenetic studies have highlighted the important role of environments in gene expression and brain development...
October 16, 2017: Annual Review of Psychology
https://www.readbyqxmd.com/read/28987006/effects-of-assortative-mate-choice-on-the-genomic-and-morphological-structure-of-a-hybrid-zone-between-two-bird-subspecies
#11
Georgy A Semenov, Elizabeth S C Scordato, David R Khaydarov, Chris C R Smith, Nolan C Kane, Rebecca J Safran
Phenotypic differentiation plays an important role in the formation and maintenance of reproductive barriers. In some cases, variation in a few key aspects of phenotype can promote and maintain divergence; hence, the identification of these traits and their associations with patterns of genomic divergence is crucial for understanding the patterns and processes of population differentiation. We studied hybridization between the alba and personata subspecies of the white wagtail (Motacilla alba), and quantified divergence and introgression of multiple morphological traits and 19,437 SNP loci on a 3,000 km transect...
October 7, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28980247/estimating-heritability-from-nuclear-family-and-pedigree-data
#12
Murielle Bochud
Heritability is a measure of familial resemblance. Estimating the heritability of a trait could be one of the first steps in the gene mapping process. This chapter describes how to estimate heritability for quantitative traits from nuclear and pedigree data using the ASSOC program in the Statistical Analysis in Genetic Epidemiology (S.A.G.E.) software package. Estimating heritability rests on the assumption that the total phenotypic variance of a quantitative trait can be partitioned into independent genetic and environmental components...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28973863/assortative-mating-and-persistent-reproductive-isolation-in-hybrids
#13
Molly Schumer, Daniel L Powell, Pablo J Delclós, Mattie Squire, Rongfeng Cui, Peter Andolfatto, Gil G Rosenthal
The emergence of new species is driven by the establishment of mechanisms that limit gene flow between populations. A major challenge is reconciling the theoretical and empirical importance of assortative mating in speciation with the ease with which it can fail. Swordtail fish have an evolutionary history of hybridization and fragile prezygotic isolating mechanisms. Hybridization between two swordtail species likely arose via pollution-mediated breakdown of assortative mating in the 1990s. Here we track unusual genetic patterns in one hybrid population over the past decade using whole-genome sequencing...
October 10, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28902471/narrow-hybrid-zones-in-spite-of-very-low-population-differentiation-in-neutral-markers-in-an-island-bird-species-complex
#14
Boris Delahaie, Josselin Cornuault, Charline Masson, Joris A M Bertrand, Yann X C Bourgeois, Borja Milá, Christophe Thébaud
Patterns of phenotypic and genic frequencies across hybrid zones provide insight into the origin and evolution of reproductive isolation. The Reunion grey white-eye, Zosterops borbonicus, exhibits parapatrically distributed plumage colour forms across the lowlands of the small volcanic island of Reunion (Mascarene archipelago). These forms meet and hybridise in regions that are natural barriers to dispersal (rivers, lava fields). Here, we investigated the relationship among patterns of differentiation at neutral genetic (microsatellite) markers, phenotypic traits (morphology and plumage colour) and niche characteristics across three independent hybrid zones...
September 13, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28857165/no-mutual-mate-choice-for-quality-in-zebra-finches-time-to-question-a-widely-held-assumption
#15
Daiping Wang, Wolfgang Forstmeier, Bart Kempenaers
Studies of mate choice typically assume that individuals prefer high quality mates and select them based on condition-dependent indicator traits. In species with biparental care, mutual mate choice is expected to result in assortative mating for quality. When assortment is not perfect, the lower quality pair members are expected to compensate by increased parental investment to secure their partner (positive differential allocation). This framework has been assumed to hold for monogamous species like the zebra finch (Taeniopygia guttata), but progress has been hampered by the difficulty to define individual quality...
November 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28817654/investigating-spousal-concordance-of-diabetes-through-statistical-analysis-and-data-mining
#16
Jong-Yi Wang, Chiu-Shong Liu, Chi-Hsuan Lung, Ya-Tun Yang, Ming-Hung Lin
OBJECTIVE: Spousal clustering of diabetes merits attention. Whether old-age vulnerability or a shared family environment determines the concordance of diabetes is also uncertain. This study investigated the spousal concordance of diabetes and compared the risk of diabetes concordance between couples and noncouples by using nationally representative data. METHODS: A total of 22,572 individuals identified from the 2002-2013 National Health Insurance Research Database of Taiwan constituted 5,643 couples and 5,643 noncouples through 1:1 dual propensity score matching (PSM)...
2017: PloS One
https://www.readbyqxmd.com/read/28812238/women-s-progress-for-men-s-gain-gender-specific-changes-in-the-return-to-education-as-measured-by-family-standard-of-living-1990-to-2009-2011
#17
ChangHwan Kim, Arthur Sakamoto
This study investigates gender-specific changes in the total financial return to education among persons of prime working ages (35-44 years) using U.S. Census data from 1990 and 2000, and the 2009-2011 American Community Survey. We define the total financial return to education as the family standard of living as measured by family income adjusted for family size. Our results indicate that women experienced significant progress in educational attainment and labor market outcomes over this time period. Ironically, married women's progress in education and personal earnings has led to greater improvement in the family standard of living for married men than for women themselves...
October 2017: Demography
https://www.readbyqxmd.com/read/28810861/the-implementation-of-long-lasting-insecticidal-bed-nets-has-differential-effects-on-the-genetic-structure-of-the-african-malaria-vectors-in-the-anopheles-gambiae-complex-in-dielmo-senegal
#18
Seynabou Sougoufara, Cheikh Sokhna, Nafissatou Diagne, Souleymane Doucouré, Pape MBacké Sembène, Myriam Harry
BACKGROUND: Mosquitoes belonging to the Anopheles gambiae complex are the main vectors of malaria in sub-Saharan Africa. Among these, An. gambiae, Anopheles coluzzii and Anopheles arabiensis are the most efficient vectors and are largely distributed in sympatric locations. However, these species present ecological and behavioural differences that impact their vectorial capacity and complicate vector-control efforts, mainly based on long-lasting insecticidal bed nets (LLINs) and indoor residual spraying (IRS)...
August 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28805044/nm%C3%AF-improved-re-implementation-of-nm-a-software-for-estimating-gene-dispersal-and-mating-patterns
#19
Igor J Chybicki
This paper introduces the NMπ computer program designed for estimation of plant mating system and seed and pollen dispersal kernels. NMπ is a re-implementation of the NM+ program and provides new features such as support for multi-core processors, explicit treatment of dioecy, the possibility of incorporating uniparentally cytoplasmic markers, the possibility of assessing assortative mating due to phenotypic similarity and inference about offspring genealogies. The probability model of parentage (the neighborhood model) accounts for missing data and genotyping errors, which can be estimated along with regular parameters of the mating system...
August 14, 2017: Molecular Ecology Resources
https://www.readbyqxmd.com/read/28797137/stay-at-home-strategy-brings-fitness-benefits-to-migrants
#20
James J Gilroy
In Focus: Lok, T., Veldhoen, L., Overdijk, O., Tinbergen, J. M., & Piersma, T. (2017). An age-dependent fitness cost of migration? Old trans-Saharan migrating spoonbills breed later than those staying in Europe, and late breeders have lower recruitment. Journal of Animal Ecology, 86, 998-1009. In Focus: Grist, H., Daunt, F., Wanless, S., Burthe, S. J., Newell, M. A., Harris, M. P., & Reid, J. M. (2017). Reproductive performance of resident and migrant males, females and pairs in a partially migratory bird. Journal of Animal Ecology, 86, 1010-1021...
September 2017: Journal of Animal Ecology
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