Zhongzhou Yang, Kanru Cai, Yuqi Liao, Wei-Chen Wu, Li Xing, Minxuan Hu, Jiali Ren, Jieyun Zhang, Xiuyun Zhu, Ke Yuan, Shunyao Wang, Hui Huang, Chunhui Yang, Mingxia Zhang, Mang Shi, Hongzhou Lu
Between 7 December 2022 and 28 February 2023, China experienced a new wave of COVID-19 that swept across the entire country and resulted in an increasing amount of respiratory infections and hospitalizations. The purpose of this study is to reveal the intensity and composition of coinfecting microbial agents. In total, 196 inpatients were recruited from The Third People's Hospital of Shenzhen, and 169 respiratory and 73 blood samples were collected for metagenomic next-generation sequencing. The total "Infectome" was characterized and compared across different groups defined by the SARS-CoV-2 detection status, age groups, and severity of disease...
February 29, 2024: Pathogens