Benjamin Terfa Igbo, Christina Jentsch, Annett Linge, Ioana Plesca, Yalçin Kuzay, Steffen Löck, Mani Sankari Kumaravadivel, Susanne Doms, Liane Stolz-Kieslich, Daniela Pollack, Sascha Brückmann, Hannes Tittlbach, Jürgen Weitz, Daniela Aust, Rudi Apolle, Marc Schmitz, Esther G C Troost
OBJECTIVE: In the era of image-guided adaptive radiotherapy, definition of the clinical target volume (CTV) is a challenge in various solid tumors, including esophageal cancer (EC). Many tumor microenvironmental factors, e.g., tumor cell proliferation or cancer stem cells, are hypothesized to be involved in microscopic tumor extension (MTE). Therefore, this study assessed the expression of FAK, ILK, CD44, HIF-1α, and Ki67 in EC patients after neoadjuvant radiochemotherapy followed by tumor resection (NRCHT+R) and correlated these markers with the MTE...
May 10, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]