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Congenital heart disease outcomes

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https://www.readbyqxmd.com/read/29922019/retroperitoneal-paraganglioma-in-a-patient-with-fontan-the-hypoxia-connection
#1
Shriprasad R Deshpande, Priyanka Patel, Neill Videlefsky, Dellys M Soler Rodriguez, Rene Romero, Matthew S Clifton
Paragangliomas are rare neuroendocrine tumors where hypoxia-inducible factor plays a critical role in tumorigenesis. It has been suggested that patients with congenital heart disease, in particular, may have cellular environment and relative hypoxia favorable to the development of these neuroendocrine tumors. Here, we present a case of an 11-year-old child with hypoplastic left heart syndrome previously palliated with Fontan procedure, diagnosed with paraganglioma on surveillance imaging. We present the clinical course, intervention, and outcome as well as review the possible contributory mechanisms...
May 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29922015/particle-embolization-of-systemic-to-pulmonary-collateral-artery-networks-in-congenital-heart-disease-technique-and-special-considerations
#2
Sarosh P Batlivala, William E Briscoe, Makram R Ebeid
Systemic-to-pulmonary artery collateral networks commonly develop in patients with single-ventricle physiology and chronic hypoxemia. Although these networks augment pulmonary blood flow, much of the flow is ineffective and contributes to cardiac volume loading. This volume loading can have detrimental effects, especially for single-ventricle patients. Some data suggest that occluding collaterals may improve outcomes after subsequent operations, especially when the volume of collateral flow is significant. Traditional practice has been to coil occlude the feeding vessel...
May 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29922007/population-based-treated-prevalence-risk-factors-and-outcomes-of-bicuspid-aortic-valve-in-a-pediatric-medicaid-cohort
#3
Avnish Tripathi, Yinding Wang, Jeanette M Jerrell
Background: We investigated the treated prevalence of bicuspid aortic valve in a pediatric population with congenital heart disease and its incident complications. Materials and Methods: A 15-year retrospective data set was analyzed. Selection criteria included age ≤17 years, enrollees in the South Carolina State Medicaid program and diagnosed as having bicuspid aortic valve on one or more service visits. Results: The 15-year-treated prevalence of predominantly isolated bicuspid aortic valve was 2% (20/1000) of pediatric congenital heart disease cases, with a non-African American: African-American ratio of 3...
May 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29914284/congenital-heart-defects-the-10-year-experience-at-a-single-center
#4
Emine Aydin, Ebru Aypar, Ahmet Oktem, Ozgur Ozyuncu, Murat Yurdakok, Murat Guvener, Metin Demircin, M Sinan Beksac
OBJECTIVE: We aimed to evaluate congenital heart disease (CHD) cases according to EUROCAT subgroup classification that were diagnosed during the prenatal period in our center. METHODS: CHDs that were prenatally diagnosed using ultrasonography and confirmed by fetal echocardiography were reviewed over a 10-year period. Subgroup classification was finalized at the post-partum period in terms of the EUROCAT guide 1.3. Congenital heart defect subtypes and obstetric outcomes (gestational week at delivery, birth weight, gender, extracardiac structural abnormalities, karyotype results if performed) were analyzed...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29912228/-the-effect-of-the-transition-care-model-on-health-perception-among-adolescents-with-congenital-heart-disease-a-quasi-experimental-study
#5
Serena Francesca Flocco, Rosario Caruso, Federica Dellafiore, Francesco Pittella, Alessandro Giamberti, Angelo Micheletti, Diana Gabriela Negura, Luciane Piazza, Massimo Chessa
BACKGROUND: The multidisciplinary standardized interventions to educate and support patients with congenital heart disease (CHD) are described as "Transition Clinic" (TC). TC represents a key element to deliver care for patients during the transition from childhood to adulthood. So far, there is a lack of empirical evidence regarding the impact of TC models on the improvement of health perception in adolescent patients with CHD (CHD-specific TC model). For this reason, the aim of this study is assess the impact of the TC model on CHD adolescent patients' health perception outcomes...
June 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29912067/rbc-exposure-in-pediatric-extracorporeal-membrane-oxygenation-epidemiology-and-factors-associated-with-large-blood-transfusion-volume
#6
Conor P O'Halloran, Peta M A Alexander, Kristofer G Andren, Jessica Mecklosky, Joshua W Salvin, Stephanie Larsen, Jill Zalieckas, Francis Fynn-Thompson, Ravi R Thiagarajan
OBJECTIVES: To quantify and identify factors associated with large RBC exposure in children supported with extracorporeal membrane oxygenation. DESIGN: Retrospective cohort study. SETTING: Single tertiary care children's hospital. PATIENTS: One-hundred twenty-two children supported with extracorporeal membrane oxygenation for greater than 12 hours during January 1, 2015, to December 31, 2016. INTERVENTIONS: None...
June 14, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29911003/bicuspid-aortic-valve-registry-of-the-italian-society-of-echocardiography-and-cardiovascular-imaging-registro-della-valvola-aortica-bicuspide-della-societ%C3%A3-italiana-di-ecocardiografia-e-cardiovascular-imaging-rationale-and-study-design
#7
Rodolfo Citro, Moreno Cecconi, Salvatore La Carrubba, Eduardo Bossone, Francesco Antonini-Canterin, Stefano Nistri, Fabio Chirillo, Ilaria Dentamaro, Michele Bellino, Alfredo Posteraro, Mauro Giorgi, Licia Petrella, Ines Monte, Vincenzo Manuppelli, Antonio Mantero, Scipione Carerj, Frank Benedetto, Paolo Colonna
Background: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%-2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root and/or ascending thoracic aorta, isthmic coarctation, aortic dissection, or wall rupture. Methods: The REgistro della Valvola Aortica Bicuspide della Società Italiana di ECocardiografia e CArdiovascular Imaging is a retrospective (from January 1, 2010)/prospective, multicenter, observational registry, expected to enroll 3000 patients with definitive diagnosis of BAV made by transthoracic and/or transesophageal echocardiography, computed tomography, cardiovascular magnetic resonance, or at surgery...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29910579/bedside-ultrasonography-screening-for-congenital-renal-anomalies-in-children-with-congenital-heart-diseases-undergoing-cardiac-repair
#8
Hussam K Hamadah, Omar Hijazi, Mohammad A Faraji, Mohamed S Kabbani
Introduction: Ultrasound (US) assessment of renal anomalies in children requiring pediatric cardiac surgery is not a standard practice. This study is highlighting the role of bedside US performed by intensivist to detect occult renal anomalies associated with congenital heart disease (CHD). Methods: A cross sectional study for 100 consecutive children with CHD admitted to Pediatric Cardiac Intensive Care Unit (PCICU) in 2015. US of kidneys screening was performed by trained pediatric cardiac intensivists to ascertain the presence of both kidneys in renal fossae without gross anomalies and to investigate if early detection of occult kidney anomaly would have any impact on outcome...
April 2018: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/29905788/extended-use-of-the-wearable-cardioverter-defibrillator-in-patients-at-risk-for-sudden-cardiac-death
#9
Valentina Kutyifa, Katherine Vermilye, Usama A Daimee, Scott McNitt, Helmut Klein, Arthur J Moss
Aims: Data on outcomes in patients using the wearable cardioverter-defibrillator (WCD) > 90 days are limited. We aimed to analyse the clinical course of patients with WCD use ≤90 days vs. WCD use >90 days. Methods and results: We assessed arrhythmia events during WCD use, and ejection fraction (EF) improvement/implantable cardioverter-defibrillator (ICD) implantation at the end of WCD use in patients with WCD use ≤90 days vs. WCD use >90 days enrolled in the WEARIT-II registry, further assessed by disease aetiology (ischaemic vs...
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29899389/calcitriol-trend-following-pediatric-cardiac-surgery-and-association-with-clinical-outcome
#10
Nina Acharya, Dermot R Doherty, Nick Barrowman, Gyaandeo Maharajh, Tara Girolamo, Katie O'Hearn, J Dayre McNally
BACKGROUND: Consistent with accepted practice in stable ambulatory populations, the majority of ICU research has evaluated vitamin D status using a single blood 25-hydroxyvitamin D (25(OH)D) level. Only a limited number of ICU studies have measured the active hormone, 1,25-dihydroxyvitamin D (calcitriol) and none have used change in calcitriol levels to evaluate axis functioning. The objective of this study was to describe the impact of Congenital Heart Disease (CHD) surgery on calcitriol levels and evaluate the relationship between change in postoperative levels and clinical course...
June 13, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29897470/concomitant-arrhythmia-surgery-in-patients-with-congenital-heart-disease
#11
Tanwier T T K Ramdjan, Elisabeth M J P Mouws, Charles Kik, Jolien W Roos-Hesselink, Ad J J C Bogers, Natasja M S de Groot
OBJECTIVES: Atrial tachyarrhythmia, including atrial fibrillation (AF), atrial flutter (AFL) and intra-atrial reentrant tachycardia (IART), occur frequently in patients with congenital heart disease (CHD), who may undergo multiple surgical procedures throughout life. However, data on the effectiveness of concomitant arrhythmia surgery in CHD patients are scarce. METHODS: Outcome of concomitant arrhythmia surgery for AF or AFL/IART was examined in 66 successive patients [31 men (47%); age at surgery: 56 ± 14 (24-78) years] with various CHD...
June 11, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29891239/prevalence-and-prognostic-significance-of-pulmonary-artery-aneurysms-in-adults-with-congenital-heart-disease
#12
Pastora Gallego, María José Rodríguez-Puras, Pilar Serrano Gotarredona, Israel Valverde, Begoña Manso, Antonio González-Calle, Alejandro Adsuar, Jose M Cubero, Luis Díaz de la Llera, Antonio Ordoñez, Amir-Reza Hosseinpour
BACKGROUND: Prevalence and prognostic significance of pulmonary artery (PA) dilatation in congenital heart disease (CHD) have never been studied systematically. METHODS: Chest X-rays of 1192 consecutive adults with CHD were reviewed. Major diameter of the PA was determined by imaging techniques in those with PA dilatation. A value >29 mm was considered abnormal. Data on anatomy, hemodynamics, residual lesions and outcomes were retrospectively collected. RESULTS: Overall prevalence of PA dilatation was 18%...
June 2, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29886666/-techniques-and-experience-which-improve-the-surgical-outcomes-of-critical-and-complex-congenital-heart-disease-in-neonates
#13
Y Pan, B Jia
Objective: To discuss the experience of early surgical intervention to critical and complex congenital heart diseases (CHD) in neonates. Methods: A retrospective study of clinical records of patients with congenital heart diseases underwent surgical intervention in one single pediatric cardiac center was performed. From January 2009 to December 2017, 841 critical and complex CHD neonates were identified at Department of Cardiovascular Surgery, Children's Hospital of Fudan University, of which 6.5% were premature...
June 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29882346/efficacy-of-prophylactic-dexmedetomidine-in-preventing-postoperative-junctional-ectopic-tachycardia-in-pediatric-cardiac-surgery-patients-a-systematic-review-and-meta-analysis
#14
REVIEW
Laxmi V Ghimire, Fu-Sheng Chou
BACKGROUND: Junctional ectopic tachycardia is a serious tachyarrhythmic complication following pediatric cardiac surgery. It is difficult to manage and is associated with significant morbidity and mortality. Conventional nonpharmacological and pharmacological measures have shown limited effects. Dexmedetomidine is an α2 agonist which has recently been shown in multiple studies to be effective. AIMS: The aim of this systematic review with meta-analysis was to evaluate the efficacy of prophylactic dexmedetomidine administration in the prevention of junctional ectopic tachycardia in pediatric patients following cardiac surgeries...
June 7, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29882315/percutaneous-endoscopic-gastrostomy-vs-surgical-gastrostomy-in-infants-with-congenital-heart-disease
#15
Lisa M Einhorn, Brad M Taicher, Nathaniel H Greene, Leon J Reinstein, Edmund H Jooste, Michael J Campbell, Kelly A Machovec
BACKGROUND: Infants with congenital heart disease often require feeding tube placement to supplement oral intake. Gastrostomy tubes may be placed by either surgical or percutaneous endoscopic methods, but there is currently no data comparing outcomes of these procedures in this population. AIMS: The aim of our retrospective study was to investigate the perioperative outcomes between the 2 groups to determine if there are clinically significant differences. METHODS: We reviewed the charts of all infants with congenital heart disease at a single academic institution having isolated surgical or percutaneous endoscopic gastrostomy tube placement from January 2011 to December 2015...
June 7, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29876506/-will-she-live-a-long-happy-life-parents-concerns-for-their-children-with-fontan-circulation
#16
Karin du Plessis, Rebecca Peters, Ingrid King, Kirsty Robertson, Jonathan Mackley, Rachel Maree, Tracy Stanley, Louise Pickford, Brian Rose, Matthew Orchard, Helen Stewart, Yves d'Udekem
Background: Families of children at the worst end of the congenital heart disease endure a significant burden which is often not clearly delineated in the clinical literature. We examined the greatest concerns of parents whose children have a Fontan circulation. Methods: Parents ( N  = 107) of children in the Australian and New Zealand Fontan Registry completed online surveys with open-ended and closed questions. A qualitative method approach incorporating thematic analyses was used...
March 2018: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29871471/feeding-dysfunctions-and-failure-to-thrive-in-neonates-with-congenital-heart-diseases
#17
Giovanna Mangili, Elena Garzoli, Youcef Sadou
Congenital heart disease (CHD) is the most common neonatal congenital malformation. The variety and severity of clinical presentation depend on the cardiac structures involved and their functional impact. The management of newborns with CHD requires a multidisciplinary approach, in which the nutritional aspect plays an important role. An adequate caloric intake during either preand post-surgical period, in fact, improves the outcome of these patients. In addition, the failure to thrive of these children in childhood has been related to long-term cognitive delay (attention deficit disorders, aggressive behaviour and poor social and emotional development)...
May 23, 2018: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/29868521/measuring-near-infrared-spectroscopy-derived-cerebral-autoregulation-in-neonates-from-research-tool-toward-bedside-multimodal-monitoring
#18
REVIEW
Liesbeth Thewissen, Alexander Caicedo, Petra Lemmers, Frank Van Bel, Sabine Van Huffel, Gunnar Naulaers
Introduction: Cerebral autoregulation (CAR), the ability of the human body to maintain cerebral blood flow (CBF) in a wide range of perfusion pressures, can be calculated by describing the relation between arterial blood pressure (ABP) and cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS). In literature, disturbed CAR is described in different patient groups, using multiple measurement techniques and mathematical models. Furthermore, it is unclear to what extent cerebral pathology and outcome can be explained by impaired CAR...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29862662/risk-factor-analysis-for-mortality-among-infants-requiring-tracheostomy
#19
Abigail R Strang, Jenna W Briddell, Patrick C Barth, Udayan K Shah, Aaron Chidekel
INTRODUCTION: An increasing number of tracheostomies are performed in infants with complex comorbidities including bronchopulmonary dysplasia (BPD) and congenital heart disease (CHD). With this shift in indications, there is an urgent need to characterize outcomes in this population. METHODS: This 5-year retrospective chart review assessed rates of 12-month mortality in infants who were ≤12 months of age at the time of tracheostomy at a tertiary care pediatric hospital and risk factors associated with death...
June 3, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29858197/supporting-optimal-neurodevelopmental-outcomes-in-infants-and-children-with-congenital-heart-disease
#20
Jennifer K Peterson
Improved survival has led to increased recognition of developmental delays in infants and children with congenital heart disease. Risk factors for developmental delays in congenital heart disease survivors may not be modifiable; therefore, it is important that lifesaving, high-technology critical care interventions be combined with nursing interventions that are also developmentally supportive. Implementing developmental care in a pediatric cardiac intensive care unit requires change implementation strategies and widespread support from all levels of health care professionals...
June 2018: Critical Care Nurse
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