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Lasers in dermatology

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https://www.readbyqxmd.com/read/27904832/frontal-fibrosing-alopecia-treatment-options
#1
Raymond Fertig, Antonella Tosti
Frontal fibrosing alopecia (FFA) is a rare dermatologic disease that causes scarring and hair loss and is increasing in prevalence worldwide. FFA patients typically present with hair loss in the frontal scalp region and eyebrows which may be associated with sensations of itching or burning. FFA is a clinically distinct variant of lichen planopilaris (LPP) that affects predominantly postmenopausal women, although men and premenopausal women may also be affected. Early diagnosis and prompt treatment are necessary to prevent definitive scarring and permanent hair loss...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27885523/a-review-of-the-mechanism-of-action-of-lasers-and-photodynamic-therapy-for-onychomycosis
#2
REVIEW
Anil Kumar Bhatta, Uma Keyal, Xiuli Wang, Emese Gellén
Onychomycosis is one of the most common diseases in the field of dermatology. It refers to the fungal infection of the nail plate or nail bed with high incidence in the general population. The available treatment options for onychomycosis have limited use due to side effects, drug interactions, and contraindications, which necessitates the application of an alternative treatment for onychomycosis. In the recent years, lasers and photodynamic therapy (PDT) have been recognized as alternative treatment options...
November 24, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27858846/the-efficacy-of-fractional-carbon-dioxide-co2-laser-combined-with-luliconazole-1-cream-for-the-treatment-of-onychomycosis-a-randomized-controlled-trial
#3
Bing Rong Zhou, Yan Lu, Felicia Permatasari, He Huang, Jin Li, Juan Liu, Jia An Zhang, Dan Luo, Yang Xu
BACKGROUND: To evaluate the efficacy of fractional carbon dioxide (CO2) laser combined with luliconazole 1% cream for the treatment of onychomycosis and to compare it with that of fractional CO2 laser alone. METHODS: This was a randomized, parallel group, 2-arm, positive-controlled, single-center, superiority trial with a 1:2 allocation ratio. Sixty patients with clinical and mycological diagnosis of onychomycosis were enrolled from the Dermatology Department of the First Affiliated Hospital of Nanjing Medical University in Nanjing, China from March 2015 to May 2015...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27805958/trial-designs-and-characteristics-in-laser-studies-in-dermatology-a-systematic-review
#4
Marie Grabas, Monica Dinulescu, Catherine Droitcourt, Alain Dupuy
BACKGROUND: Lasers are increasingly used in Dermatology. Clinical studies are among the best means to assess their efficacy. OBJECTIVE: To obtain an overview of therapeutic laser studies in the field of Dermatology, the authors conducted a systematic review to describe the types of study published over the past 25 years, and their reporting in the abstracts. METHODS: The authors selected interventional studies that evaluated laser treatment on human subjects with skin diseases...
October 25, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27786580/postinflammatory-hyperpigmentation-associated-with-treatment-of-solar-lentigines-using-a-q-switched-532-nm-nd-yag-laser-a-multicenter-survey
#5
Hyun Ji Kang, Jung Im Na, Jong Hee Lee, Mi Ryung Roh, Joo Yeon Ko, Sung Eun Chang
PURPOSE: To characterize the risk factors of Korean patients for postinflammatory hyperpigmentation (PIH) during treatment of solar lentigines using a Q-switched 532-nm Nd: YAG (QS 532 NY) laser. MATERIALS AND METHODS: The present retrospective multicenter study was conducted at the dermatology clinics of five tertiary hospitals in Korea. Between October 2007 and January 2013, 516 patients were enrolled and reviewed for clinical features and factors associated with PIH...
November 15, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27688445/three-hundred-patients-treated-with-ultrapulsed-980-nm-diode-laser-for-skin-disorders
#6
Uwe Wollina
The use of lasers in skin diseases is quite common. In contrast to other laser types, medical literature about 980 nm ultrapulsed diode laser is sparse in dermatology. Herein, we report the use of ultrapulsed diode 980 nm laser in 300 patients with vascular lesions, cysts and pseudocysts, infectious disease, and malignant tumors. This laser is a versatile tool with excellent safety and efficacy in the hands of the experienced user.
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27668924/improving-health-related-quality-of-life-in-wounded-warriors-the-promising-benefits-of-laser-hair-removal-to-the-residual-limb-prosthetic-interface
#7
Nathanial R Miletta, Sang Kim, Amanda Lezanski-Gujda, Anthony M Rossi, Jason D Marquart
BACKGROUND: Wounded warriors with lower limb amputations using prosthetics commonly develop dermatologic complaints at the residual limb-prosthetic interface, which impact their health-related quality of life (HRQOL). To optimize this interface, military dermatologists routinely treat the subset of issues related to the pilosebaceous unit with laser hair removal (LHR). OBJECTIVE: To characterize the impact of residual limb skin conditions on HRQOL in wounded warriors using lower limb prosthetics before and after treatment with LHR...
October 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27645917/penetration-of-630nm-laser-and-5-aminolevulinic-acid-in-tissue-with-intralesional-photodynamic-therapy
#8
María Jesús Suárez Valladares, Manuel Ángel Rodríguez Prieto, Ricard Serra Llusà
Photodynamic therapy is a common treatment in dermatology for several diseases, its main limitation is the penetration of photosensitizer and light in the tissue. However intralesional photodynamic therapy is a new technique where the photosensitizer and sometimes a 630nm laser beam are applied inside the lesión, so it allows achieve deeper penetration. It has been used to treat basal cell carcinoma, hidradenitis suppurativa or keloids.
September 16, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27640402/objective-severity-does-not-capture-the-impact-of-rosacea-acne-scarring-and-photoaging-in-patients-seeking-laser-therapy
#9
C L Thomas, B Kim, J Lam, S Richards, A See, S Kalouche, R D Paver, P Fernández Peñas
BACKGROUND: Measures of quality of life (QOL) and patient satisfaction are of great importance in dermatology, as both impact upon treatment adherence and health outcomes. Patients' assessment of QOL often differs from their doctors' predictions and their assessments of skin disease severity do not correlate with patients' own perceptions. The development of laser technology has facilitated successful treatment of many skin conditions, but studies on patient satisfaction are lacking. OBJECTIVES: Our aim was to determine the extent of discordance between patient and dermatologist-assessed disease severity and assess the impact of acne scarring, rosacea and photoaging on QOL...
September 18, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27631010/nonconventional-use-of-flash-lamp-pulsed-dye-laser-in-dermatology
#10
Steven Nisticò, Piero Campolmi, Silvia Moretti, Ester Del Duca, Nicola Bruscino, Rossana Conti, Andrea Bassi, Giovanni Cannarozzo
Flash-lamp pulsed-dye laser (FPDL) is a nonablative technology, typically used in vascular malformation therapy due to its specificity for hemoglobin. FPDL treatments were performed in a large group of patients with persistent and/or recalcitrant different dermatological lesions with cutaneous microvessel involvement. In particular, 149 patients (73 males and 76 females) were treated. They were affected by the following dermatological disorders: angiokeratoma circumscriptum, genital and extragenital viral warts, striae rubrae, basal cell carcinoma, Kaposi's sarcoma, angiolymphoid hyperplasia, and Jessner-Kanof disease...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27624669/non-ablative-fractional-laser-to-facilitate-transdermal-delivery
#11
Sindhu S Ganti, Ajay K Banga
The advances in laser technology have led to its rapidly expanding applications in dermatology. This study aims at the novel use of a non-ablative fractional laser to enhance transdermal permeation of diclofenac sodium and sumatriptan succinate. The effects of the laser on skin were characterized visually with dye binding, scanning electron microscopy, pore permeability index, and histology. In vitro transdermal permeation of drugs through laser treated and untreated human dermatomed skin was analyzed over 24 h and quantified by HPLC...
November 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27623742/laser-thermal-therapy-monitoring-using-complex-differential-variance-in-optical-coherence-tomography
#12
William C Y Lo, Néstor Uribe-Patarroyo, Ahhyun S Nam, Martin Villiger, Benjamin J Vakoc, Brett E Bouma
Conventional thermal therapy monitoring techniques based on temperature are often invasive, limited by point sampling, and are indirect measures of tissue injury, while techniques such as magnetic resonance and ultrasound thermometry are limited by their spatial resolution.  The visualization of the thermal coagulation zone at high spatial resolution is particularly critical to the precise delivery of thermal energy to epithelial lesions. In this work, an integrated thulium laser thermal therapy monitoring system was developed based on complex differential variance (CDV), which enables the 2D visualization of the dynamics of the thermal coagulation process at high spatial and temporal resolution with an optical frequency domain imaging system...
September 14, 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27622266/preventing-identifying-and-managing-cosmetic-procedure-complications-part-2-lasers-and-chemical-peels
#13
Megan Brown
Part 1 of this series highlighted some of the potential complications that have been associated with soft tissue augmentation and botulinum toxin injections. In part 2, tips for how dermatology residents may prevent, identify, and manage complications from lasers and chemical peels for optimal patient outcomes are provided.
August 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/27622163/spondylodiscitis-and-bacteremia-due-to-staphylococcus-hyicus-in-an-immunocompetent-man
#14
Maud Foissac, Maria Lekaditi, Bouchra Loutfi, Agnès Ehrhart, Frédéric-Antoine Dauchy
INTRODUCTION: Staphylococcus hyicus is a coagulase-variable Staphylococcus spp. well-known by veterinarians since it is the major agent of a severe cutaneous infection in piglets called exudative epidermitis. In other species the symptoms of infection are quite different. Human cases are uncommon but seem to occur more frequently after repeated contacts with farm animals. CASE REPORT: We report the case of a 58-year-old man suffering from debilitating subacute lumbar pain, in whom diagnosis of infectious spondylodiscitis was based on spine MRI and positive microbiological results...
September 2016: Germs
https://www.readbyqxmd.com/read/27616192/a-randomized-clinical-trial-on-the-comparison-between-hair-shaving-and-snipping-prior-to-laser-hair-removal-sessions-in-women-suffering-from-hirsutism
#15
Robabeh Alijanpour, Fatemeh Aliakbarpour
BACKGROUND AND OBJECTIVES: Hirsutism or excess hair growth is a common dermatological problem in females, affecting up to 10% of females worldwide. We aimed this study to compare the two hair-shortening methods shaving vs. snipping among hirsute women regarding the outcome of the therapy and also the paradoxical hypertrichosis phenomenon (terminal hair regrowth) 6 months after the final therapy session. MATERIALS AND METHODS: In this study, 129 premenopausal women affected by hirsutism were randomly divided into two study groups according to hair-shortening method: shaving as group A (66 patients) and hair shortening by scissor as group B (63 patients)...
September 11, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27594596/combination-of-fractional-qsrl-and-ipl-for-melasma-treatment-in-chinese-population
#16
La-Ga Tong, Yan Wu, Bin Wang, Xue-Gang Xu, Han-Deng Tu, Hong-Duo Chen, Yuan-Hong Li
BACKGROUND: Melasma is the most common and distressing pigmentary disorder presenting to dermatology clinics. Various treatment protocols for melasma have been suggested in the previous literature and applied in various clinical settings. However, no satisfactory therapy has been widely accepted. OBJECTIVE: To evaluate the efficiency and safety of a combination treatment with fractional Q-switched ruby laser (QSRL) and intense pulsed light (IPL) for melasma in Chinese population...
November 18, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27592504/fractional-radiofrequency-treatment-in-acne-scars-systematic-review-of-current-evidence
#17
E Forbat, F Al-Niaimi
Fractional radiofrequency (FRF) is renowned for its use in cosmetic dermatology, with regard to the treatment of rhytides, striae, scarring and cellulite. We have systemically analysed its evidence for the use of FRF in acne scars. Our search identified 15 articles, one single-blinded randomised controlled trial, two split-face trials and thirteen prospective clinical studies, mostly single-centred. Case reports were excluded. In total 362 patients were treated. The longest follow-up was for 210 days, and on average the follow-up was for three months, varying between one and seven months...
October 13, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27563635/the-comparison-between-modified-kligman-formulation-versus-kligman-formulation-and-intense-pulsed-light-in-the-treatment-of-the-post-burn-hyperpigmentation
#18
Amir Hossein Siadat, Fariba Iraji, Reza Bahrami, Mohammad Ali Nilfroushzadeh, Ali Asilian, Sheila Shariat, Zahra Nikyar, Safura Bokaie
BACKGROUND: Post inflammatory hyperpigmentation (PIH) is a common problem occurs following many dermatologic diseases and medical interventions. Different modalities including topical agents, lasers and intense pulsed light (IPL) are suggested for treatment of the post-burn PIH. In the current study, we evaluated the efficacy of IPL plus modified Kligman cream (MODIFIED KLIGMAN CREAM) versus MODIFIED KLIGMAN CREAM alone in the treatment of the post-burn PIH. MATERIALS AND METHODS: This was a randomized, non-blinded clinical trial...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27538097/treatment-of-vitiligo-with-308-nm-excimer-laser-our-experience-from-a-two-year-follow-up-of-979-chinese-patients
#19
Y Fa, Y Lin, X J Chi, W H Shi, J L Wang, X Guo, J H Geng, H X Liu, F R Zhang
BACKGROUND: The 308-nm excimer laser had been proved to be a time-efficient and potent therapeutic alternative for the management of vitiligo. Different results had been reported in different ethnic populations. OBJECTIVE: To investigate the efficacy and related contributing factors of 308-nm excimer laser in Chinese vitiligo patients. METHODS: A total of 979 Chinese patients (3478 lesions) with progressive-stage vitiligo who had received 308-nm excimer laser treatment were recruited from the vitiligo clinic of Shandong Provincial Hospital of Dermatology &Venereology from 2012 to 2014...
August 18, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27513585/ingenol-mebutate-treatment-in-a-patient-with-gorlin-syndrome
#20
Marco Stieger, Robert E Hunger
BACKGROUND: Gorlin syndrome, also known as the basal cell nevus syndrome (OMIM #109400), is a rare autosomal-dominant genetic disease. The disease, which shows mutation of the patched receptor gene (PTCH1) of the sonic hedgehog pathway, is characterized by developing multiple basal cell carcinomas (BCCs) in adolescent patients. Other clinical features include mandibular keratocysts, palmar and plantar pits, skeletal abnormalities and malformations central nervous system and genital tract...
2016: Dermatology: International Journal for Clinical and Investigative Dermatology
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